Clozapine and prazosin slow the rhythm of head movements during focused stereotypy induced by d-amphetamine in rats

Psychopharmacology

Volumn 192, Issue 2, 2007, Pages 219-230

  Fowler, Stephen C ^a   Pinkston, Jonathan W ^a   Vorontsova, Elena ^a  

^a UNIVERSITY OF KANSAS   (United States)

Author keywords

10 Hz rhythm; Antipsychotic; Clozapine; d Amphetamine; Force plate actometer; Prazosin; Rat; Rhythmic head movements; Spectral analysis; Stereotypy

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; CLOZAPINE; DEXAMPHETAMINE; PRAZOSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG TOLERANCE; HEAD MOVEMENT; MALE; MOTOR DYSFUNCTION; NONHUMAN; PRIORITY JOURNAL; RAT; STEREOTYPY;

ADRENERGIC ALPHA-ANTAGONISTS; ANALYSIS OF VARIANCE; ANIMALS; ANTIPSYCHOTIC AGENTS; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM STIMULANTS; CLOZAPINE; DEXTROAMPHETAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG TOLERANCE; HEAD MOVEMENTS; MALE; PRAZOSIN; RATS; RATS, SPRAGUE-DAWLEY; SPECTRUM ANALYSIS; STEREOTYPED BEHAVIOR;

EID: 34247576344     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-007-0705-3     Document Type: Article

References (34)

1. Andreasen NC, Nopoulos P, O'Leary DS, Miller DD, Wassink T, Flaum M (1999) Defining the phenotype of schizophrenia: cognitive dysmetria and its neural mechanisms. Biol Psychiatry 46:908-920
2. Auclair A, Cotecchia S, Golinski J, Tassin J-P (2002) D-amphetamine fails to increase extracellular dopamine levels in mice lacking α1b-adrenergic receptors: relationship between functional and nonfunctional dopamine release. J Neurosci 22:9150-9154
3. Bakshi VP, Geyer MA (1997) Phencyclidine-induced deficits in prepulse inhibition of startle are blocked by prazosin, an alpha-1 noradrenergic antagonist. J Pharmacol Exp Ther 283:666-674
4. Baldessarini RJ, Centorrino F, Flood JG, Volpicelli SA, Huston-Lyons D, Cohen BM (1993) Tissue concentration of clozapine and its metabolites in the rat. Neuropsychopharmacology 9:117-124
5. Bonuccelli U, Ceravolo R, Salvetti S, D'Avino C, DelDotto P, Rossi G, Murri L (1997) Clozapine in Parkinson's disease tremor. Effects of acute and chronic administration. Neurology 49:1587-1590
6. Canales JJ, Graybiel AM (2000) A measure of striatal function predicts motor stereotypy. Nat Neurosci 3:377-383
7. Ceravolo R, Salvetti S, Piccini P, Lucetti C, Gambaccini G, Bonuccelli U (1999) Acute and chronic effects of clozapine in essential tremor. Mov Disord 14:468-472
8. Coward DM (1993) The pharmacology of clozapine-like, atypical antipsychotics. In: Barnes T (ed) Antipsychotic drugs and their side effects. Academic, New York, pp 27-44
9. Das S, Fowler SC (1995) Acute and subchronic effects of clozapine on licking in rats: tolerance to disruptive effects on number of licks, but no tolerance to rhythm slowing. Psychopharmacology (Berl) 120:249-255
10. Das S, Fowler SC (1996) Similarity of clozapine's and olanzapine's acute effects on rats' lapping behavior. Psychopharmacology 123:374-378
11. Ellinwood EH, Cohen S (1971) D-amphetamine abuse. Science 171:420-421
12. Fowler SC, Birkestrand BR, Chen R, Moss SJ, Vorontsova, E, Wang G, Zarcone TJ (2001) A force-plate actometer for quantitating rodent behaviors: illustrative data on locomotion, rotation, spatial patterning, stereotypies and tremor. J Neurosci Methods 107:107-124
13. Fowler SC, Birkestrand B, Chen R, Vorontsova E, Zarcone TJ (2003) Behavioral sensitization to d-amphetamine in rats: changes in the rhythm of head movements during focused stereotypies. Psychopharmacology 170:167-177
14. Fowler SC, McKerchar TL, Zarcone TJ (2005a) Response dynamics: Measurement of the force and rhythm of motor responses in laboratory animals. In: LeDoux M (ed) Animal models of movement disorders. Academic, San Diego, CA, pp 73-100
15. Fowler SC, McKerchar TL, Zarcone TJ (2005b) Motor effects of typical and atypical antipsychotic drugs in rodents. In: LeDoux M (ed) Animal models of movement disorders. Academic, San Diego, CA, pp 735-744
16. Gabbay H, Lev-Tov A (2004) Alpha-1 adrenoceptor agonists generate a "fast" NMDA receptor-independent motor rhythm in the neonatal rat spinal cord. J Neurophysiol 92:997-1010
17. Kuczenski R, Segal DS (1999) Sensitization of d-amphetamine- induced stereotypy during the acute response. J Pharmacol Exp Ther 288:699-709
18. Leucht S, Wahlbeck K, Hamann J, Kissling W (2003) New generation antipsychotics versus low-potency conventional antipsychotics: a systematic review and meta-analysis. Lancet 361:1581-1589
19. Leysen JE, Janssen PM, Schotte A, Luyten WH, Megens AA (1993) Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors. Psychopharmacology (Berl) 112(1 Suppl):S40-S54
20. Lieberman JA (1998) Maximizing clozapine therapy: managing side effects. J Clin Psychiatry 59(Suppl 3):38-43
21. Owens MJ, Risch SC (1995) Atypical antipsychotics. In: Schatzberg AF, Nemeroff CB (eds) Textbook of psychopharmacology. American Psychiatric, Washington, DC, pp 263-280
22. Prus AJ, Philbin SD, Pehrson AL, Porter JH (2006) Discriminative properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle. Behav Pharmacol 17:185-194
23. Rebec GV, White IM, Puotz JK (1997) Responses in neurons in dorsal striatum during d-amphetamine-induced focused stereotypy. Psychopharmacology (Berl) 130:434-351
24. Robertson A, MacDonald C (1984) Atypical Neuroleptics clozapine and thioridazine enhance d-amphetamine-induced stereotypy. Pharmacol Biochem Behav 21:97-101
25. Robinson TE, Becker JB (1986) Enduring changes in brain and behavior produced by chronic d-amphetamine administration: a review and evaluation of animal models of d-amphetamine psychosis. Brain Res 396:157-198
26. Schiorring E (1971) D-amphetamine induced selective stimulation of certain behaviour items with concurrent inhibition of others in an open-field test with rats. Behaviour 39:1-17
27. Schotte A, Janssen PF, Gommeren W, Luyten WH, Van Gompel P, Lesage AS, De Loore K, Leysen JE (1996) Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding. Psychopharmacology (Berl) 124:57-73
28. A receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochem Res 25:1587-1601
29. Stanford JA, Fowler SC (1997) Subchronic effects of clozapine and haloperidol on rats' forelimb force and duration during a press-while-licking task. Psychopharmacology (Berl) 130:249-253
30. Stille G, Lauener H, Eichenberger E (1971) The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine (clozapine). Farmaco [Prat] 26:603-625
31. Sun W, Ginovart N, Ko F, Seeman P, Kapur S (2003) In vivo evidence for dopamine-mediated internalization of D2-receptors after d-amphetamine: differential findings with [3H]raclopride versus [3H]spiperone. Mol Pharmacol 63:456-462
32. Tessel RE, Barrett JE (1986) Antagonism of the behavioral effects of cocaine and d-amphetamine by prazosin. Psychopharmacology (Berl) 90:436-440
33. Vanderschuren, JLMJ, Beemster P, Schoffelmeer ANM (2003) On the role of noradrenaline in psychostimulant-induced psychomotor activity and sensitization. Psychopharmacology 169:176-185
34. Varvel SA, Vann RE,Wise LE, Philibin SD, Porter JH (2002) Effects of antipsychotic drugs on operant responding after acute and repeated administration. Psychopharmacology (Berl) 160:182-191