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Journal of Computer-Aided Molecular Design

Volumn 14, Issue 8, 2000, Pages 769-786

A pharmacophore model for dopamine D4 receptor antagonists

(3) Bostrom J a Gundertofte, K b Liljefors, T a

Author keywords

Bioactive conformation; Conformational analysis; D2 D4 selectivity; Dopamine D2; Dopamine D4; Enantioselectivity; Pharmacophore model; Solvation energies

Indexed keywords

AMINES; CONFORMATIONS; ELECTRONIC PROPERTIES; NEUROPHYSIOLOGY; PHARMACODYNAMICS;

BIOACTIVE CONFORMATION; CONFORMATIONAL ANALYSIS; D2/D4 SELECTIVITY; DOPAMINE; DOPAMINE D2; DOPAMINE D4; PHARMACOPHORE MODELS; RECEPTOR ANTAGONISTS; SOLVATION ENERGY;

ENANTIOSELECTIVITY;

CLOROTEPINE; DOPAMINE 2 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE RECEPTOR BLOCKING AGENT; TEFLUDAZINE;

ARTICLE; BINDING AFFINITY; CONFORMATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG SELECTIVITY; DRUG STRUCTURE; ENANTIOMER; ENERGY; MOLECULAR MODEL; PHARMACOPHORE; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 0033670977 PISSN: 0920654X EISSN: None Source Type: Journal
DOI: 10.1023/A:1008198026843 Document Type: Article

Times cited : (21)

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