Mediator of DNA damage checkpoint 1 (MDC1) contributes to high NaCL-induced activation of the osmoprotective transcription factor TonEBP/OREBP

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Kunin, Margarita ^a,b   Dmitrieva, Natalia I ^a   Gallazzini, Morgan ^a   Shen, Rong Fong ^a,c   Wang, Guanghui ^a   Burg, Maurice B ^a   Ferraris, Joan D ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b SHEBA MEDICAL CENTER   (Israel)

^c NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATM PROTEIN; CELL PROTEIN; MEDIATOR OF DNA DAMAGE CHECKPOINT 1; OSMOTIC RESPONSE ELEMENT BINDING PROTEIN; SMALL INTERFERING RNA; SODIUM CHLORIDE; TONICITY RESPONSIVE ENHANCER BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; DNA BINDING PROTEIN; MDC1 PROTEIN, HUMAN; NUCLEAR PROTEIN; PROTEIN SERINE THREONINE KINASE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR NFAT; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; CELL NUCLEUS; CELL STRAIN HEK293; CONTROLLED STUDY; DNA DAMAGE; DNA STRAND BREAKAGE; GENE SILENCING; GENETIC TRANSCRIPTION; IMMUNOPRECIPITATION; MASS SPECTROMETRY; OSMOTIC STRESS; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; TRANSACTIVATION; WESTERN BLOTTING; ACTIVE TRANSPORT; AMINO ACID SEQUENCE; CELL LINE; CHEMISTRY; CYTOPLASM; DOSE RESPONSE; DRUG EFFECT; GENETICS; HUMAN; IMMUNOBLOTTING; METABOLISM; MOLECULAR GENETICS; SOLUBILITY;

ACTIVE TRANSPORT, CELL NUCLEUS; AMINO ACID SEQUENCE; CELL CYCLE PROTEINS; CELL LINE; CELL NUCLEUS; CYTOPLASM; DNA DAMAGE; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMMUNOBLOTTING; MASS SPECTROMETRY; MOLECULAR SEQUENCE DATA; NFATC TRANSCRIPTION FACTORS; NUCLEAR PROTEINS; PROTEIN-SERINE-THREONINE KINASES; SODIUM CHLORIDE; SOLUBILITY; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEINS;

EID: 77957868397     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012108     Document Type: Article

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