Cross-reactivity of herpesvirus-specific CD8 T cell lines toward allogeneic class I MHC molecules

PLoS ONE

Volumn 5, Issue 8, 2010, Pages

  Morice, Alexis ^a   Charreau, Beatrice ^b   Neveu, Berangere ^a   Brouard, Sophie ^a,b,c   Soulillou, Jean Paul ^a,b,c   Bonneville, Marc ^a   Houssaint, Elisabeth ^a   Degauque, Nicolas ^a,b,c  

^a UNIVERSITÉ DE NANTES   (France)

^b INSERM   (France)

^c NANTES UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; CYTOMEGALOVIRUS ANTIGEN PP65; EPITOPE; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; IMMEDIATE EARLY PROTEIN BZLF1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PROTEIN BMLF1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VIRUS PROTEIN; HLA ANTIGEN;

ALLELE; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; CD8+ T LYMPHOCYTE; CELL SPECIFICITY; CELL STRAIN COS7; CONTROLLED STUDY; CROSS REACTION; CYTOKINE PRODUCTION; CYTOTOXICITY; ENDOTHELIUM CELL; EPSTEIN BARR VIRUS; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNOMAGNETIC SEPARATION; LYMPHOBLASTOID CELL LINE; LYMPHOID CELL LINE; NONHUMAN; VIRUS CELL TRANSFORMATION; AMINO ACID SEQUENCE; ANIMAL; CELL LINE; CELL STRAIN COS1; CERCOPITHECUS; CHEMISTRY; CYTOMEGALOVIRUS; GENE EXPRESSION REGULATION; IMMUNOLOGY; METABOLISM; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; SPECIES DIFFERENCE;

HERPESVIRIDAE; HUMAN HERPESVIRUS 4; HUMAN HERPESVIRUS 5;

AMINO ACID SEQUENCE; ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; CROSS REACTIONS; CYTOMEGALOVIRUS; ENDOTHELIAL CELLS; EPITOPES; GENE EXPRESSION REGULATION; HERPESVIRUS 4, HUMAN; HLA ANTIGENS; HUMANS; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, QUATERNARY; SPECIES SPECIFICITY;

EID: 77957861661     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0012120     Document Type: Article

References (46)

1. Cainelli F, Vento S (2002) Infections and solid organ transplant rejection: a cause-and-effect relationship? Lancet Infect Dis 2: 539-549.
2. Razonable RR, Paya CV (2003) Herpesvirus infections in transplant recipients: current challenges in the clinical management of cytomegalovirus and Epstein-Barr virus infections. Herpes 10: 60-65.
3. Soderberg-Naucler C, Emery VC (2001) Viral infections and their impact on chronic renal allograft dysfunction. Transplantation 71: SS24-30.
4. Streblow DN, Orloff SL, Nelson JA (2007) Acceleration of allograft failure by cytomegalovirus. Curr Opin Immunol 19: 577-582.
5. Hodson EM, Jones CA, Webster AC, Strippoli GF, Barclay PG, et al. (2005) Antiviral medications to prevent cytomegalovirus disease and early death in recipients of solid-organ transplants: a systematic review of randomised controlled trials. Lancet 365: 2105-2115.
6. Gerth UC, Moss PA, Bell JI, McMichael AJ (1995) T-cell receptor usage of major histocompatibility complex class I restricted peptide-specific T-lymphocytes. Ann N Y Acad Sci 756: 12-18.
7. Grunewald J, Wigzell H (1999) T cell receptors in health and disease. Introduction. Springer Semin Immunopathol 21: 1-4.
8. Hislop AD, Gudgeon NH, Callan MF, Fazou C, Hasegawa H, et al. (2001) EBV-specific CD8+ T cell memory: relationships between epitope specificity, cell phenotype, and immediate effector function. J Immunol 167: 2019- 2029.
9. Sylwester AW, Mitchell BL, Edgar JB, Taormina C, Pelte C, et al. (2005) Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects. J Exp Med 202: 673-685.
10. Tan LC, Gudgeon N, Annels NE, Hansasuta P, O'Callaghan CA, et al. (1999) A re-evaluation of the frequency of CD8+ T cells specific for EBV in healthy virus carriers. J Immunol 162: 1827-1835.
11. Lanzavecchia A, Sallusto F (2000) Dynamics of T lymphocyte responses: intermediates, effectors, and memory cells. Science 290: 92-97.
12. Burrows SR, Khanna R, Burrows JM, Moss DJ (1994) An alloresponse in humans is dominated by cytotoxic T lymphocytes (CTL) cross-reactive with a single Epstein-Barr virus CTL epitope: implications for graft-versus-host disease. J Exp Med 179: 1155-1161.
13. Burrows SR, Khanna R, Silins SL, Moss DJ (1999) The influence of antiviral T-cell responses on the alloreactive repertoire. Immunol Today 20: 203-207.
14. Burrows SR, Silins SL, Khanna R, Burrows JM, Rischmueller M, et al. (1997) Cross-reactive memory T cells for Epstein-Barr virus augment the alloresponse to common human leukocyte antigens: degenerate recognition of major histocompatibility complex-bound peptide by T cells and its role in alloreactivity. Eur J Immunol 27: 1726-1736.
15. Gamadia LE, Remmerswaal EB, Surachno S, Lardy NM, Wertheim-van Dillen PM, et al. (2004) Cross-reactivity of cytomegalovirus-specific CD8+ T cells to allo-major histocompatibility complex class I molecules. Transplantation 77: 1879-1885.
16. Koelle DM, Chen HB, McClurkan CM, Petersdorf EW (2002) Herpes simplex virus type 2-specific CD8 cytotoxic T lymphocyte cross-reactivity against prevalent HLA class I alleles. Blood 99: 3844-3847.
17. Wills MR, Carmichael AJ, Mynard K, Jin X, Weekes MP, et al. (1996) The human cytotoxic T-lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T-cell receptor usage of pp65-specific CTL. J Virol 70: 7569-7579.
18. Khanna R, Burrows SR, Moss DJ (1995) Immune regulation in Epstein-Barr virus-associated diseases. Microbiol Rev 59: 387-405.
19. Saulquin X, Ibisch C, Peyrat MA, Scotet E, Hourmant M, et al. (2000) A global appraisal of immunodominant CD8 T cell responses to Epstein-Barr virus and cytomegalovirus by bulk screening. Eur J Immunol 30: 2531-2539.
20. Scotet E, Peyrat MA, Saulquin X, Retiere C, Couedel C, et al. (1999) Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes. Eur J Immunol 29: 973-985.
21. Steven NM, Leese AM, Annels NE, Lee SP, Rickinson AB (1996) Epitope focusing in the primary cytotoxic T cell response to Epstein-Barr virus and its relationship to T cell memory. J Exp Med 184: 1801-1813.
22. Steven NM, Annels NE, Kumar A, Leese AM, Kurilla MG, et al. (1997) Immediate early and early lytic cycle proteins are frequent targets of the Epstein-Barr virus-induced cytotoxic T cell response. J Exp Med 185: 1605-1617.
23. Miles JJ, Elhassen D, Borg NA, Silins SL, Tynan FE, et al. (2005) CTL recognition of a bulged viral peptide involves biased TCR selection. J Immunol 175: 3826-3834.
24. Weekes MP, Wills MR, Mynard K, Carmichael AJ, Sissons JG (1999) The memory cytotoxic T-lymphocyte (CTL) response to human cytomegalovirus infection contains individual peptide-specific CTL clones that have undergone extensive expansion in vivo. J Virol 73: 2099-2108.
25. Trautmann L, Rimbert M, Echasserieau K, Saulquin X, Neveu B, et al. (2005) Selection of T cell clones expressing high-affinity public TCRs within Human cytomegalovirus-specific CD8 T cell responses. J Immunol 175: 6123-6132.
26. Amir AL, D'Orsogna LJA, Roelen DL, van Loenen MM, Hagedoorn RS, et al. (2010) Allo-HLA reactivity of virus-specific memory T-cells is common. Blood 115: 3146-3157.
27. Heemskerk MB, Roelen DL, Dankers MK, van Rood JJ, Claas FH, et al. (2005) Allogeneic MHC class I molecules with numerous sequence differences do not elicit a CTL response. Hum Immunol 66: 969-976.
28. Maruya E, Takemoto S, Terasaki PI (1993) HLA matching: identification of permissible HLA mismatches. Clin Transpl. pp 511-520.
29. Kawase T, Morishima Y, Matsuo K, Kashiwase K, Inoko H, et al. (2007) High-risk HLA allele mismatch combinations responsible for severe acute graft-versus-host disease and implication for its molecular mechanism. Blood 110: 2235-2241.
30. Moya-Quiles MR, Muro M, Torio A, Sanchez-Bueno F, Miras M, et al. (2003) Human leukocyte antigen-C in short- and long-term liver graft acceptance. Liver Transpl 9: 218-227.
31. Finn OJ, Debruyne LA, Bishop DK (1996) T cell receptor (TCR) repertoire in alloimmune responses. Int Rev Immunol 13: 187-207.
32. Gaschet J, Denis C, Milpied N, Hallet MM, Romagne F, et al. (1995) Alterations of T cell repertoire after bone marrow transplantation: characterization of over-represented subsets. Bone Marrow Transplant 16: 427-435.
33. Argaet VP, Schmidt CW, Burrows SR, Silins SL, Kurilla MG, et al. (1994) Dominant selection of an invariant T cell antigen receptor in response to persistent infection by Epstein-Barr virus. J Exp Med 180: 2335-2340.
34. Doxiadis II, Smits JM, Schreuder GM, Persijn GG, van Houwelingen HC, et al. (1996) Association between specific HLA combinations and probability of kidney allograft loss: the taboo concept. Lancet 348: 850-853.
35. Epperson DE, Pober JS (1994) Antigen-presenting function of human endothelial cells. Direct activation of resting CD8 T cells. J Immunol 153: 5402-5412.
36. Pober JS, Orosz CG, Rose ML, Savage CO (1996) Can graft endothelial cells initiate a host anti-graft immune response? Transplantation 61: 343-349.
37. Suarez Y, Shepherd BR, Rao DA, Pober JS (2007) Alloimmunity to human endothelial cells derived from cord blood progenitors. J Immunol 179: 7488-7496.
38. Kreisel D, Krupnick AS, Gelman AE, Engels FH, Popma SH, et al. (2002) Non-hematopoietic allograft cells directly activate CD8+ T cells and trigger acute rejection: an alternative mechanism of allorecognition. Nat Med 8: 233-239.
39. Davodeau F, Peyrat MA, Hallet MM, Gaschet J, Houde I, et al. (1993) Close correlation between Daudi and mycobacterial antigen recognition by human gamma delta T cells and expression of V9JPC1 gamma/V2DJC delta-encoded T cell receptors. J Immunol 151: 1214-1223.
40. Le Bas-Bernardet S, Hourmant M, Coupel S, Bignon JD, Soulillou JP, et al. (2003) Non-HLA-type endothelial cell reactive alloantibodies in pre-transplant sera of kidney recipients trigger apoptosis. Am J Transplant 3: 167-177.
41. Bodinier M, Peyrat MA, Tournay C, Davodeau F, Romagne F, et al. (2000) Efficient detection and immunomagnetic sorting of specific T cells using multimers of MHC class I and peptide with reduced CD8 binding. Nat Med 6: 707-710.
42. Neveu B, Echasserieau K, Hill T, Kuus-Reichel K, Houssaint E, et al. (2006) Impact of CD8-MHC class I interaction in detection and sorting efficiencies of antigen-specific T cells using MHC class I/peptide multimers: contribution of pMHC valency. Int Immunol 18: 1139-1145.
43. David-Ameline J, Lim A, Davodeau F, Peyrat MA, Berthelot JM, et al. (1996) Selection of T cells reactive against autologous B lymphoblastoid cells during chronic rheumatoid arthritis. J Immunol 157: 4697-4706.
44. Espevik T, Nissen-Meyer J (1986) A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/tumor necrosis factor from human monocytes. J Immunol Methods 95: 99-105.
45. Brichard V, Van Pel A, Wolfel T, Wolfel C, De Plaen E, et al. (1993) The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J Exp Med 178: 489-495.
46. Landais E, Morice A, Long HM, Haigh TA, Charreau B, et al. (2006) EBV-specific CD4+ T cell clones exhibit vigorous allogeneic responses. J Immunol 177: 1427-1433.