Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: Towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes

European Journal of Immunology

Volumn 29, Issue 3, 1999, Pages 973-985

  Scotet, Emmanuel ^a   Peyrat, Marie Alix ^a   Saulquin, Xavier ^a   Retiere, Christelle ^a   Couedel, Christelle ^a   Davodeau, François ^a   Dulphy, Nicolas ^b   Toubert, Antoine ^b   Bignon, Jean Denis ^c   Lim, Annick ^d   Vie, Henri ^a   Hallet, Marie Martine ^a   Liblau, Roland ^e   Weber, Michel ^f   Berthelot, Jean Marie ^f   Houssaint, Elisabeth ^a   Bonneville, Marc ^a  

^a INSTITUT DE BIOLOGIE   (France)

^b SAINT LOUIS HOSPITAL   (France)

^c Ctr Regionaux de Transfus Sanguine   (France)

^d INSTITUT PASTEUR   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^f Centre Hospitalier Régional   (France)

Author keywords

Arthritis; Autoimmunity; Herpes virus; Multiple sclerosis; T cell

Indexed keywords

CD8 ANTIGEN;

ADULT; AGED; ANIMAL CELL; ANKYLOSING SPONDYLITIS; ANTIVIRAL ACTIVITY; ARTICLE; AUTOIMMUNE DISEASE; CELLULAR IMMUNITY; CLINICAL ARTICLE; CONTROLLED STUDY; ENCEPHALITIS; FEMALE; HERPES VIRUS; HUMAN; HUMAN CELL; HUMAN CYTOMEGALOVIRUS; INFLAMMATION; LYMPHOCYTE CLONE; MALE; MULTIPLE SCLEROSIS; NONHUMAN; OSTEOARTHRITIS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; PSORIATIC ARTHRITIS; REITER SYNDROME; RHEUMATOID ARTHRITIS; T LYMPHOCYTE; UVEITIS;

EID: 0032985551     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1521-4141(199903)29:03<973::aid-immu973>3.0.co;2-p     Document Type: Article

References (39)

1. Harris, E. D., Rheumatoid arthritis: pathophysiology and implications for therapy. N. Engl. J. Med. 1990. 322: 1277-1289.
2. Phillips, P. E., Viral arthritis. Curr. Opin. Rheumatol. 1997. 9: 337-344.
3. Sieper, J. and Kingsley, G., Recent advances in the pathogenesis of reactive arthritis. Immunol. Today 1996. 17: 160-163.
4. Venables, P. J. W., Epstein-Barr virus infection and autoimmunity in rheumatoid arthritis. Ann. Rheum. Dis. 1988. 47: 265-269.
5. Rhodes, G., Rumpold, H., Kurki, P., Patrick, K. M., Carson, D. A. and Vaughan, J. H., Autoantibodies in infectious mononucleosis have specificity for the glycine-alanine repeating region of the Epstein-Barr virus nuclear antigen. J. Exp. Med. 1987. 165: 1026-1040.
6. Fox, R. I., Sportsman, R., Rhodes, G. H., Luke, J., Pearson, G. and Vaughan, J. H., Rheumatoid arthritis synovial membrane contains a 62,000-molecular-weight protein that shares an antigenic epitope with the Epstein-Barr virus encoded EBNA-1 antigen. J. Clin. Invest. 1986. 77: 1539-1547.
7. Alspaugh, M. A., Henle, G., Lennette, E. T. and Henle, W., Elevated levels of antibodies to Epstein-Barr virus antigens in sera and synovial fluids of patients with rheu~matoid arthritis. J. Clin. Invest. 1981. 67: 1134-1140.
8. Venables, P. J. W., Antibodies to EBV-encoded proteins in rheumatoid arthritis. In Smolen, E., Kalden, J. and Maini, R. N. (Eds.) Rheumatoid Arthritis. Springer Verlag, Berlin 1992, pp. 281-295.
9. Lotz, M. and Roudier, J., Epstein-Barr virus and rheumatoid arthritis. In Smolen, E., Kalden, J. and Maini, R. N. (Eds.) Rheumatoid arthritis. Springer Verlag, Berlin 1992, pp 257-280.
10. Fox, R. I., Luppi, M., Pisa, P. and Kang, H. I., Potential role of Epstein-Barr virus in Sjögren's syndrome and rheumatoid arthritis. J. Rheumatol. 1992. 19: 18-24.
11. Zhang, L., Nikkari, S. and Skurnik, M., Detection of herpes viruses by polymerase chain reaction in lymphocytes from patients with rheumatoid arthritis. Arthritis Rheum. 1993. 36: 1080-1086.
12. Brousset, P., Caulier, M., Cantagrel, A., Dromer, C., Mazières, B. and Delsol, G., Absence of Epstein-Barr virus carrying cells in synovial membranes and subcutaneous nodules of patients with rheumatoid arthritis. Ann. Rheum. Dis. 1993. 52: 608-609.
13. Newkirk, M. M., Watanabe-Duffy, K. N., Leclerc, J., Lambert, N. and Shiroky, J. B., Detection of cytomegalovirus, Epstein-Barr virus and Herpes virus-6 in patients with rheumatoid arthritis with or without Sjögren's syndrome. Br. J. Rheumatol. 1994. 33: 317-322.
14. David-Ameline, J., Lim, A., Davodeau, F., Peyrat, M. A., Berthelot, J. M., Semana, G., Pannetier, C., Gaschet, J., Vié, H., Even, J. and Bonneville, M., Selection of T cells reactive against autologous B lymphoblastoid cells during chronic rheumatoid arthritis. J. Immunol. 1996. 157: 4697-4706.
15. Scotet, E., David-Ameline, J., Peyrat, M. A., Moreau-Aubry, A., Pinczon, D., Lim, A., Even, J., Semana, G., Berthelot, J. M., Breathnach, R., Bonneville, M. and Houssaint, E., T cell response to Epstein-Barr virus transactivators in chronic rheumatoid arthritis. J. Exp. Med. 1996. 184: 1791-1800.
16. Brichard, V., van Pel, A., Wölfel, T., Wölfel, C., De Plaen, E., Lethé, B., Coulie, P. and Boon, T., The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas. J. Exp. Med. 1993. 178: 489-495.
17. Seed, B. and Aruffo, A., Molecular cloning of the CD2 antigen, the T cell erythrocyte receptor, by a rapid immunoselection procedure. Proc. Natl. Acad. Sci. USA 1987. 84: 3365-3369.
18. Mocarski, E. S., Cytomegaloviruses and their replication. In Fields, B. N., Knipe, D. M., Howley, P. M. et al. (Eds) Fields Virology. Raven Press, Philadelphia 1996, pp 2447-2492.
19. Wiertz, E. J. H., Tortorella, D., Bogyo, M., Yu, J., Mothes, W., Jones, T. R., Rapoport, T. A. and Ploegh, H. L., Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction. Nature 1996. 384: 432-438.
20. Wiertz, E. J. H., Jones, T. R., Sun, L., Bogyo, M., Geuze, H. J. and Ploegh, H. L., The human cytomegalovirus US11 gene product dislocates MHC class I heavy chains from the endoplasmic reticulum to the cytosol. Cell 1996. 84: 769-779.
21. Hengel, H., Koopmann, J. O., Flohr, T., Muranyi, W., Goulmy, E., Hammerling, G. J., Koszinowski, U. H. and Momburg, F., A viral ER-resisent glycoprotein inactivates the MHC-encoded peptide transporter. Immunity 1997. 6: 623-632.
22. Borysiewicz, L. K., Hickling, J. K., Graham, S., Sinclair, J., Cranage, M. P., Smith, G. L. and Patrick Sissons, J. G., Human cytomegalovirus-specific cytotoxic T cells. J. Exp. Med. 1988. 168: 919-931.
23. Riddell, S. R., Rabin, M., Geballe, A. P., Britt, W. J. and Greenberg, P.D., Class I MHC-restricted cytotoxic T lymphocyte recognition of cells infected with human cytomegalovirus does not require endogenous viral gene expression. J. Immunol. 1991. 146: 2795-2804.
24. Wills, M. R., Carmichael, A. J., Mynard, K., Jin, X., Weekes, M. P., Plachter, B. and Patrick-Simmons, J. G., The human cytotoxic T lymphocyte (CTL) response to cytomegalovirus is dominated by structural protein pp65: frequency, specificity, and T cell receptor usage of pp65-specific CTL. J. Virol. 1996. 70: 7569-7579.
25. Vié, H., Chevalier, S., Garand, R., Moisan, J. P., Praloran, V., Devilder, M. C., Moreau, J. F. and Soulillou, J. P., Clonal expansion of lymphocytes bearing the gamma/delta receptor in a patient with a large granular lymphocyte disorder. Blood 1989. 74: 285-296.
26. Liao, H. X. and Haynes, B. F., Role of adhesion molecules in the pathogenesis of rheumatoid arthritis. Rheum. Dis. Clin. North Am. 1995. 21: 715-740.
27. Mickey, W. F., Hsu, B. L. and Kimura, H., T lymphocyte entry into the central nervous system. J. Neurosci. Res. 1991. 28: 254-260.
28. Koide, J., Takada, K., Sugiura, M., Sekine, H., Ito, T., Saito, K., Mori, S., Takeuchi, T., Uchida, S. and Abe, T., Spontaneous establishment of an Epstein-Barr virus-infected fibroblast line from the synovial tissue of a rheumatoid arthritis patient. J. Virol. 1997. 71: 2478-2481.
29. Soderberg-Naucler, C., Fisch, K. N. and Nelson, J. A., Reactivation of latent human cytomegalovirus by allogeneic stimulation of blood cells from healthy donors. Cell 1997. 91: 119-126.
30. Koopman, W. J., The future of biologics in the treatment of rheumatoid arthritis. Sem. Arthritis Rheum. 1994. 23: 50-67.
31. Jokinen, E. I., Mottonen, T. T., Hannonen, P. J., Makela, M. and Arvilommi, H. S., Prediction of severe rheumatoid arthritis using Epstein-Barr virus. Br, J. Rheumatol. 1994. 33: 917-922.
32. Arnett, F. C., Edworthy, S. M., Bloch, D. A., McShane, D. J., Fries, J. F., Cooper, N. S., Healey, L. A., Kaplan, S. R., Liang, M. H., Luthra, H. S., Medsger, T. A., Mitchell, D. M., Neustadt, D. H., Pinals, R. S., Schaller, J. G., Sharp, J. T., Wilder, R. L. and Hunder, G. G., The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum. 1988. 31: 315-324.
33. Dougados, M., Linden, S., Juhlin, R., Huitfeldt, B., Amor, B., Calin, A., Cats, A., Dijkmans, B., Olivieri, I., Pasero, G., Veys, E. and Zeidler, H., The european spondylarthropathy study group preliminary criteria for the classification of spondylarthropathy. Arthritis Rheum. 1991. 34: 1218-1227.
34. Tonks, S., Marsh, S. G. E., Bunce, M., Moses, J. H., Krausa, P., Sadler, A. M., Petronzelli, F. and Bodmer, J. G., HLA class I DNA typing study. In Charron, D. (Ed). Genetic diversity of HLA: functional and medical implication. Vol I. EDK, Paris 1997, pp 199-215.
35. Cereb, N., Maye, P., Lee, S., Kong, Y. and Yang, S. Y., Locus-specific amplification of HLA class I genes from genomic DNA: locus-specific sequences in the first and third introns of HLA-A, -B and -C alleles. Tissue Antigens 1995. 45: 1-11.
36. Buyse, I., Decorte, R., Baens, M., Cuppens, H., Semana, G., Edmonds, M. P., Marynen, P. and Cassiman, J. J., Rapid DNA typing of class II HLA antigens using the polymerase chain reaction and reverse dot blot hybridization. Tissue Antigens 1993. 41: 1-14.
37. Davodeau, F., Peyrat, M. A., Gaschet, J., Hallet, M. M., Triebel, F., Vié, H., Kabelitz, D. and Bonneville, M., Surface expression of functional T cell receptor chains formed by interlocus recombination on human T lymphocytes. J. Exp. Med. 1994. 180: 1685-1694.
38. Davodeau, F., Peyrat, M. A., Houde, I., Hallet, M. M., Vié, H. and Bonneville, M., Peripheral selection of antigen receptor junctional features in a major human γδ T cell subset. Eur. J. Immunol. 1993. 23: 804-808.
39. Espevik, T. and Nissen-Meyer, J., A highly sensitive cell line, WEHI 164 clone 13, for measuring cytotoxic factor/ tumor necrosis factor from human monocytes. J. Immunol. Methods 1986. 95: 99-105.