Hypoxia and reoxygenation of primary human hepatocytes induce proteome changes of glucose metabolism, oxidative protection and peroxisomal function

International Journal of Molecular Medicine

Volumn 26, Issue 4, 2010, Pages 577-584

  Strey, Christoph W ^a   Gestrich, Johannes ^a   Beckhaus, Tobias ^a   Marquez Pinilla, Rosa Maria ^a   Oppermann, Elsie ^a   Mönch, Christian ^a   Lambris, John D ^b   Karas, Michael ^a   Bechstein, Wolf O ^a  

^a GOETHE UNIVERSITY   (Germany)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Cell culture; Human hepatocytes; Hypoxia reoxygenation; Mass spectrometry; Two dimensional gel electrophoresis

Indexed keywords

(S) 2 HYDROXY ACID OXIDASE; CARBAMOYL PHOSPHATE SYNTHASE; CATALASE ISOFORM 2; F1 ATP SYNTHASE ALPHA SUBUNIT 1; FRUCTOSE BISPHOSPHATASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GALACTOSE 1 PHOSPHATE URIDYLYLTRANSFERASE; GLUCOSE; GLUTATHIONE TRANSFERASE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEAT SHOCK PROTEIN 70 PROTEIN 5; HYDROXYACID OXIDASE 1; LIPOCORTIN 2; PEROXIREDOXIN; PEROXIREDOXIN 2; PEROXIREDOXIN 3; PHOSPHOENOLPYRUVATE CARBOXYKINASE (GTP); PHOSPHOGLYCERATE KINASE; PROTEOME; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATE SYNTHASE; THIOREDOXIN PEROXIDASE; THIOSULFATE SULFURTRANSFERASE; UNCLASSIFIED DRUG;

ADAPTATION; ADULT; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GLUCOSE METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER FUNCTION; LIVER ISCHEMIA; LIVER PROTECTION; LIVER SURGERY; LIVER TRANSPLANTATION; MALE; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; OXIDATION; OXIDATIVE STRESS; PEROXISOME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEOMICS; REOXYGENATION; TWO DIMENSIONAL ELECTROPHORESIS;

AGED; CELL HYPOXIA; CELLS, CULTURED; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FEMALE; GLUCOSE; HEPATOCYTES; HUMANS; LACTATE DEHYDROGENASES; MALE; MIDDLE AGED; OXIDATIVE STRESS; OXYGEN; PEROXISOMES; PROTEOME; PROTEOMICS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 77957858844     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000502     Document Type: Article

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