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Volumn 21, Issue 5, 2008, Pages 611-620

Autocrine stimulation of human hepatocytes triggers late DNA synthesis and stabilizes long-term differentiation in vitro

Author keywords

Autocrine stimulation; c Met; Cytokeratins; Hepatocytes; Interleukin 6

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; CYTOKERATIN 18; CYTOKERATIN 19; HUMAN ALBUMIN; INTERLEUKIN 6; SCATTER FACTOR; SCATTER FACTOR RECEPTOR; ALBUMINOID; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBRINOGEN; KERATIN;

EID: 46449134674     PISSN: 11073756     EISSN: None     Source Type: Journal    
DOI: 10.3892/ijmm.21.5.611     Document Type: Article
Times cited : (2)

References (38)
  • 1
    • 33645926676 scopus 로고    scopus 로고
    • Three-dimensional culture of porcine fetal liver cells for a bioartificial liver
    • Ehashi T, Ohshima N and Miyoshi H: Three-dimensional culture of porcine fetal liver cells for a bioartificial liver. J Biomed Mater Res A 77: 90-96, 2006.
    • (2006) J Biomed Mater Res A , vol.77 , pp. 90-96
    • Ehashi, T.1    Ohshima, N.2    Miyoshi, H.3
  • 2
    • 32444435766 scopus 로고    scopus 로고
    • Propagation and functional characterization of serum-free cultured porcine hepatocytes for downstream applications
    • Schneider C, Aurich H, Wenkel R and Christ B: Propagation and functional characterization of serum-free cultured porcine hepatocytes for downstream applications. Cell Tissue Res 323: 433-442, 2006.
    • (2006) Cell Tissue Res , vol.323 , pp. 433-442
    • Schneider, C.1    Aurich, H.2    Wenkel, R.3    Christ, B.4
  • 4
    • 29744467490 scopus 로고    scopus 로고
    • Which are the right cells to be used in a bioartificial liver?
    • Chamuleau. RA, Deurholt T and Hoekstra R: Which are the right cells to be used in a bioartificial liver? Metab Brain Dis 20: 327-335, 2005.
    • (2005) Metab Brain Dis , vol.20 , pp. 327-335
    • Chamuleau, R.A.1    Deurholt, T.2    Hoekstra, R.3
  • 8
    • 8844254689 scopus 로고    scopus 로고
    • Hepatic tissue engineering for adjunct and temporary liver support: Critical technologies
    • Chan C, Berthiaume F, Nath BD, Tilles AW, Toner M and Yarmush ML: Hepatic tissue engineering for adjunct and temporary liver support: critical technologies. Liver Transpl 10: 1331-1342, 2004.
    • (2004) Liver Transpl , vol.10 , pp. 1331-1342
    • Chan, C.1    Berthiaume, F.2    Nath, B.D.3    Tilles, A.W.4    Toner, M.5    Yarmush, M.L.6
  • 10
    • 33644946812 scopus 로고    scopus 로고
    • c-Met responsiveness of isolated hepatocytes evaluated in an in vitro de-differentiation model
    • Boost KA, Kim HJ, Engl T, Oppermann E, Jonas D, Oertl A and Blaheta RA: c-Met responsiveness of isolated hepatocytes evaluated in an in vitro de-differentiation model. Int J Mol Med 17: 475-482, 2006.
    • (2006) Int J Mol Med , vol.17 , pp. 475-482
    • Boost, K.A.1    Kim, H.J.2    Engl, T.3    Oppermann, E.4    Jonas, D.5    Oertl, A.6    Blaheta, R.A.7
  • 11
    • 85047174321 scopus 로고    scopus 로고
    • Controlled and reversible induction of differentiation and activation of adult human hepatocytes by a biphasic culture technique
    • Auth MK, Hilgard P, Markus BH, Bechstein WO and Blaheta RA: Controlled and reversible induction of differentiation and activation of adult human hepatocytes by a biphasic culture technique. World J Gastroenterol 11: 2090-2097, 2005.
    • (2005) World J Gastroenterol , vol.11 , pp. 2090-2097
    • Auth, M.K.1    Hilgard, P.2    Markus, B.H.3    Bechstein, W.O.4    Blaheta, R.A.5
  • 12
    • 0031961443 scopus 로고    scopus 로고
    • Blaheta RA, Kronenberger B, Woitaschek D, Auth MK, Scholz M, Weber S, Schuldes H, Encke A and Markus BH: Dedifferentiation of human hepatocytes by extracellular matrix proteins in vitro: quantitative and qualitative investigation of cytokeratin 7, 8, 18, 19 and vimentin filaments. J Hepatol 28: 677-690, 1998.
    • Blaheta RA, Kronenberger B, Woitaschek D, Auth MK, Scholz M, Weber S, Schuldes H, Encke A and Markus BH: Dedifferentiation of human hepatocytes by extracellular matrix proteins in vitro: quantitative and qualitative investigation of cytokeratin 7, 8, 18, 19 and vimentin filaments. J Hepatol 28: 677-690, 1998.
  • 14
    • 33745533559 scopus 로고    scopus 로고
    • Liver stem cells and their implication in hepato-cellular and cholangiocarcinoma
    • Roskams T: Liver stem cells and their implication in hepato-cellular and cholangiocarcinoma. Oncogene 25: 3818-3822, 2006.
    • (2006) Oncogene , vol.25 , pp. 3818-3822
    • Roskams, T.1
  • 16
    • 0029928703 scopus 로고    scopus 로고
    • Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium
    • Block GD, Locker J, Bowen WC, Petersen BE, Katyal S, Strom SC, Riley T, Howard TA and Michalopoulos GK: Population expansion, clonal growth, and specific differentiation patterns in primary cultures of hepatocytes induced by HGF/SF, EGF and TGF alpha in a chemically defined (HGM) medium. J Cell Biol 132: 1133-1149, 1996.
    • (1996) J Cell Biol , vol.132 , pp. 1133-1149
    • Block, G.D.1    Locker, J.2    Bowen, W.C.3    Petersen, B.E.4    Katyal, S.5    Strom, S.C.6    Riley, T.7    Howard, T.A.8    Michalopoulos, G.K.9
  • 17
    • 0032899212 scopus 로고    scopus 로고
    • Morphogenetic events in mixed cultures of rat hepatocytes and nonparenchymal cells maintained in biological matrices in the presence of hepatocyte growth factor and epidermal growth factor
    • Michalopoulos GM, Bowen WC, Zajac VE, Beer-Stolz D, Watkins S, Kostrubsky V and Strom SC: Morphogenetic events in mixed cultures of rat hepatocytes and nonparenchymal cells maintained in biological matrices in the presence of hepatocyte growth factor and epidermal growth factor. Hepatology 29: 90-100, 1999.
    • (1999) Hepatology , vol.29 , pp. 90-100
    • Michalopoulos, G.M.1    Bowen, W.C.2    Zajac, V.E.3    Beer-Stolz, D.4    Watkins, S.5    Kostrubsky, V.6    Strom, S.C.7
  • 18
    • 0029872054 scopus 로고    scopus 로고
    • Hepatocytic cells form bile duct-like structures within a three-dimensional collagen gel matrix
    • Nishikawa Y, Tokusashi Y, Kadohama T, Nishimori H and Ogawa K: Hepatocytic cells form bile duct-like structures within a three-dimensional collagen gel matrix. Exp Cell Res 223: 357-371, 1996.
    • (1996) Exp Cell Res , vol.223 , pp. 357-371
    • Nishikawa, Y.1    Tokusashi, Y.2    Kadohama, T.3    Nishimori, H.4    Ogawa, K.5
  • 19
    • 0031910343 scopus 로고    scopus 로고
    • Human hepatocyte growth factor down-regulates the expression of cytochrome P450 isoenzymes in human hepatocytes in primary culture
    • Donato MT, Gomez-Lechon MJ, Jover R, Nakamura T and Castell JV: Human hepatocyte growth factor down-regulates the expression of cytochrome P450 isoenzymes in human hepatocytes in primary culture. J Pharmacol Exp Ther 284: 760-767, 1998.
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 760-767
    • Donato, M.T.1    Gomez-Lechon, M.J.2    Jover, R.3    Nakamura, T.4    Castell, J.V.5
  • 20
    • 0029905271 scopus 로고    scopus 로고
    • The hepatocyte growth factor regulates the synthesis of acute-phase proteins in human hepatocytes: Divergent effect on interleukin-6-stimulated genes
    • Guillen MI, Gomez-Lechon MJ, Nakamura T and Castell JV: The hepatocyte growth factor regulates the synthesis of acute-phase proteins in human hepatocytes: divergent effect on interleukin-6-stimulated genes. Hepatology 23: 1345-1352, 1996.
    • (1996) Hepatology , vol.23 , pp. 1345-1352
    • Guillen, M.I.1    Gomez-Lechon, M.J.2    Nakamura, T.3    Castell, J.V.4
  • 21
    • 0032535560 scopus 로고    scopus 로고
    • Liver regeneration and alpha-fetoprotein messenger RNA expression in the retrorsine model for hepatocyte transplantation
    • Dabeva MD, Laconi E, Oren R, Petkov PM, Hurston E and Shafritz DA: Liver regeneration and alpha-fetoprotein messenger RNA expression in the retrorsine model for hepatocyte transplantation. Cancer Res 58: 5825-5834, 1998.
    • (1998) Cancer Res , vol.58 , pp. 5825-5834
    • Dabeva, M.D.1    Laconi, E.2    Oren, R.3    Petkov, P.M.4    Hurston, E.5    Shafritz, D.A.6
  • 22
    • 0024213059 scopus 로고
    • The development of the intrahepatic bile ducts in man: A keratin-immunohistochemical study
    • Van Eyken P, Sciot R, Callea. F, Van der Steen K, Moerman P and Desmet VJ: The development of the intrahepatic bile ducts in man: a keratin-immunohistochemical study. Hepatology 8: 1586-1595, 1988.
    • (1988) Hepatology , vol.8 , pp. 1586-1595
    • Van Eyken, P.1    Sciot, R.2    Callea, F.3    Van der Steen, K.4    Moerman, P.5    Desmet, V.J.6
  • 25
    • 33646839459 scopus 로고    scopus 로고
    • Contact inhibition of hepatocyte growth regulated by functional association of the c-Met/ hepatocyte growth factor receptor and LAR protein-tyrosine phosphatase
    • Machide M, Hashigasako A, Matsumoto K and Nakamura T: Contact inhibition of hepatocyte growth regulated by functional association of the c-Met/ hepatocyte growth factor receptor and LAR protein-tyrosine phosphatase. J Biol Chem 281: 8765-8772, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 8765-8772
    • Machide, M.1    Hashigasako, A.2    Matsumoto, K.3    Nakamura, T.4
  • 26
    • 2342544903 scopus 로고    scopus 로고
    • Phosphorylation of hepatocyte growth factor receptor and epidermal growth factor receptor of human hepatocytes can be maintained in a (3D) collagen sandwich culture system
    • Engl T, Boost KA, Leckel K, Beecken WD, Jonas D, Oppermann E, Auth MK, Schaudt A, Bechstein WO and Blaheta RA: Phosphorylation of hepatocyte growth factor receptor and epidermal growth factor receptor of human hepatocytes can be maintained in a (3D) collagen sandwich culture system. Toxicol In Vitro 18: 527-532, 2004.
    • (2004) Toxicol In Vitro , vol.18 , pp. 527-532
    • Engl, T.1    Boost, K.A.2    Leckel, K.3    Beecken, W.D.4    Jonas, D.5    Oppermann, E.6    Auth, M.K.7    Schaudt, A.8    Bechstein, W.O.9    Blaheta, R.A.10
  • 27
    • 6344263492 scopus 로고    scopus 로고
    • Interleukin-6 augments hepatocyte growth factor-induced liver regeneration; involvement of STAT3 activation
    • Kaido T, Oe H and Imamura M: Interleukin-6 augments hepatocyte growth factor-induced liver regeneration; involvement of STAT3 activation. Hepatogastroenterology 51: 1667-1670, 2004.
    • (2004) Hepatogastroenterology , vol.51 , pp. 1667-1670
    • Kaido, T.1    Oe, H.2    Imamura, M.3
  • 28
    • 33646887377 scopus 로고    scopus 로고
    • Hepatic sinusoidal endothelial cells promote hepatocyte proliferation early after partial hepatectomy in rats
    • Ping C, Xiaoling D, Jin Z, Jiahong D, Jiming D and Lin Z: Hepatic sinusoidal endothelial cells promote hepatocyte proliferation early after partial hepatectomy in rats. Arch Med Res 37: 576-583, 2006.
    • (2006) Arch Med Res , vol.37 , pp. 576-583
    • Ping, C.1    Xiaoling, D.2    Jin, Z.3    Jiahong, D.4    Jiming, D.5    Lin, Z.6
  • 29
    • 27844465896 scopus 로고    scopus 로고
    • IL-6 modulates hepatocyte proliferation via induction of HGF/p21cip1: Regulation by SOCS3
    • Sun R, Jaruga B, Kulkami S, Sun H and Gao B: IL-6 modulates hepatocyte proliferation via induction of HGF/p21cip1: regulation by SOCS3. Biochem Biophys Res Commun 338: 1943-1949, 2005.
    • (2005) Biochem Biophys Res Commun , vol.338 , pp. 1943-1949
    • Sun, R.1    Jaruga, B.2    Kulkami, S.3    Sun, H.4    Gao, B.5
  • 30
    • 0034234736 scopus 로고    scopus 로고
    • Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: Comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells
    • Yokomuro S, Tsuji H, Lunz JG III, Sakamoto T, Ezure T, Murase N and Demetris AJ: Growth control of human biliary epithelial cells by interleukin 6, hepatocyte growth factor, transforming growth factor beta1, and activin A: comparison of a cholangiocarcinoma cell line with primary cultures of non-neoplastic biliary epithelial cells. Hepatology 32: 26-35, 2000.
    • (2000) Hepatology , vol.32 , pp. 26-35
    • Yokomuro, S.1    Tsuji, H.2    Lunz III, J.G.3    Sakamoto, T.4    Ezure, T.5    Murase, N.6    Demetris, A.J.7
  • 31
    • 0026556132 scopus 로고
    • Increase in interleukin 6 (IL-6) and IL-6 receptor expression in a human multiple myeloma cell line, U-266, during long-term in vitro culture and the development of a possible autocrine IL-6 loop
    • Jernberg-Wiklund H, Pettersson M, Carlsson M and Nilsson K: Increase in interleukin 6 (IL-6) and IL-6 receptor expression in a human multiple myeloma cell line, U-266, during long-term in vitro culture and the development of a possible autocrine IL-6 loop. Leukemia 6: 310-318, 1992.
    • (1992) Leukemia , vol.6 , pp. 310-318
    • Jernberg-Wiklund, H.1    Pettersson, M.2    Carlsson, M.3    Nilsson, K.4
  • 33
    • 33645848942 scopus 로고    scopus 로고
    • Regulation of hepatocyte cell cycle progression and differentiation by type I collagen structure
    • Hansen LK, Wilhelm J and Fassett JT: Regulation of hepatocyte cell cycle progression and differentiation by type I collagen structure. Curr Top Dev Biol 72: 205-236, 2006.
    • (2006) Curr Top Dev Biol , vol.72 , pp. 205-236
    • Hansen, L.K.1    Wilhelm, J.2    Fassett, J.T.3
  • 34
    • 0027429163 scopus 로고
    • Damage to neurons in culture following medium change: Role of glutamine and extracellular generation of glutamate
    • Driscoll BF, Deibler GE, Law MJ and Crane AM: Damage to neurons in culture following medium change: role of glutamine and extracellular generation of glutamate. J Neurochem 61: 1795-1800, 1993.
    • (1993) J Neurochem , vol.61 , pp. 1795-1800
    • Driscoll, B.F.1    Deibler, G.E.2    Law, M.J.3    Crane, A.M.4
  • 36
    • 0036052861 scopus 로고    scopus 로고
    • Renewal of the culture medium induces a temporary decrease in the gap junctional communication accompanied by degradation and re-establishment of gap junctions in the V79-4 Chinese hamster cell line
    • Vitek J, Oborilova E, Mazura P and Benesova M: Renewal of the culture medium induces a temporary decrease in the gap junctional communication accompanied by degradation and re-establishment of gap junctions in the V79-4 Chinese hamster cell line. Folia Biol (Praha) 48: 108-113, 2002.
    • (2002) Folia Biol (Praha) , vol.48 , pp. 108-113
    • Vitek, J.1    Oborilova, E.2    Mazura, P.3    Benesova, M.4
  • 37
    • 0030281572 scopus 로고    scopus 로고
    • Effect of medium renewal during culture in two different culture systems on development to blastocysts from in vitro produced early bovine embryos
    • Fukui Y, Lee ES and Araki N: Effect of medium renewal during culture in two different culture systems on development to blastocysts from in vitro produced early bovine embryos. J Anim Sci 74: 2752-2758, 1996.
    • (1996) J Anim Sci , vol.74 , pp. 2752-2758
    • Fukui, Y.1    Lee, E.S.2    Araki, N.3
  • 38
    • 0027080816 scopus 로고
    • Differentiation and dedifferentiation of the human monocytic leukemia cell line, U937
    • Hosoya H and Marunouchi T: Differentiation and dedifferentiation of the human monocytic leukemia cell line, U937. Cell Struct Funct 17: 263-269, 1992.
    • (1992) Cell Struct Funct , vol.17 , pp. 263-269
    • Hosoya, H.1    Marunouchi, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.