Mechanism, origin, and evolution of anoxia tolerance in animals

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology

Volumn 130, Issue 4, 2001, Pages 435-459

  Hochachka, P W ^a   Lutz, P L ^b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Channel arrest; Hypometabolism; Hypoxia inducible factor 1 (HIF 1); Hypoxia sensing; Hypoxic brain; Hypoxic hepatocyte; Mitochondrial biogenesis; Protein synthesis; Spike arrest

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLYCOLYTIC ENZYME; HEMOPROTEIN; HYPOXIA INDUCIBLE FACTOR 1; ION CHANNEL; TRANSCRIPTION FACTOR SP3;

ANIMAL CELL; ANOXIA; BIOGENESIS; CONFERENCE PAPER; DEFENSE MECHANISM; DOWN REGULATION; ENZYME REGULATION; ENZYME REPRESSION; GENE ACTIVATION; GENE EXPRESSION; HYPOXIA; ION TRANSPORT; LIVER CELL; MITOCHONDRIAL MEMBRANE; NONHUMAN; OXYGEN CONSUMPTION; PHYLOGENY; POLYSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; STEADY STATE; TURTLE;

ANIMALIA; PISCES; TESTUDINES;

EID: 0034751813     PISSN: 10964959     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1096-4959(01)00408-0     Document Type: Conference Paper

References (100)

1. Air-breathing fishes: Metabolic biochemistry of the first diving vertebrates
2. Promoter analysis of the human succinate dehydrogenase iron-protein gene: Both nuclear respiratory factors NRF1 and NRF2 are required
3. Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin-producing cells
4. Anaerobiosis and the toxicity of cyanide in turtles
5. Induction of stress proteins in cultured myogenic cells: Molecular signals for the activation of heat shock transcription during ischemia
6. 2+ concentrations
7. Surviving hypoxia without really dying
8. Oxyconformity in the intertidal worm Sipunculus nudus: The mitochondrial background and energetic consequences
9. +-ATPase and constant membrane potential in hepatocytes: Support for channel arrest
10. Microcalorimetric measurement of reversible metabolic suppression induced by anoxia in isolated hepatocytes
11. Erythropointen: A model system for studying oxygen-dependent gene regulation
12. Relationships between aerobic and anaerobic energy production in turtle brain in situ
13. The physiology of diving in a north-temperate and three tropical turtle species
14. Oncogenic alterations of metabolism
15. Hypoxia regulates b-enolase and pyruvate kinase-M promoters by modulating Sp1/Sp3 binding to a conserved GC element
16. Anoxic CNS membrane: Mechanisms of collapse and stabilization
17. Channel arrest: Implications from membrane resistance in turtle neurons
18. Reduced ionic conductance in turtle brain
19. A microcalorimetric study of turtle cortical slices: Insights into brain metabolic depression
20. Erythropoietin: Oxygen-dependent control of erythropoiesis and its failure in renal disease
21. Electroencephalogram activity in the anoxic turtle brain
22. Oxygen-regulated control elements in the phosphoglycerate kinase l and lactate dehydrogenase A genes: Similarities with the erythropoietin 3′ enhancer
23. Hypoxic regulation of lactate dehydrogenase A. Interaction between hypoxia-inducible factor 1 and cAMP response elements
24. Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1
25. Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours
26. Biochemical principles of metabolic suppression
27. Metabolic dormancy in aquatic invertebrates
28. Downregulation of cellular metabolism during environmental stress: Mechanisms and implications
29. Defense strategies against hypoxia and hypothermia
30. Adaptability of metabolic efficiencies under chronic hypoxia in man
31. Roles of the smallest metabolite - The hydrogen ion as a metabolite intermediate and a metabolic regulator
32. Oxygen - A key regulatory metabolite in metabolic defense against hypoxia
33. Pinniped diving response mechanism and evolution: A window on the paradigm of comparative biochemistry and physiology
34. Unifying theory of hypoxia tolerance: Molecular/metabolic defense and rescue mechanisms for surviving oxygen lack
35. 2-dependent degradation domain via the ubiquitin-proteasome pathway
36. +-ATPase activity in two anoxia-tolerant vertebrates: Crucian carp and freshwater turtle
37. 2 sensing
38. Targeting of HIF-alpha to the von Hippel-Lindau ubiquitylation complex by O-2-regulated prolyl hydroxylation
39. Regulation of the hypoxia-inducible transcription factor 1-alpha by the ubiquitin-proteasome pathway
40. Modulation of the glucagon-dependent activation of the PEPCK gene by oxygen in rat hepatocyte cultures
41. A ferro-heme protein senses oxygen levels which modulate the glucagon dependent activation of the PEPCK gene in rat hepatocyte cultures
42. Acute depression of mitochondrial protein synthesis during anoxia: Contributions of oxygen sensing, matrix acidification, and redox state
43. Hypoxia is a strong inducer of vascular endothelial growth factor mRNA expression in the heart
44. Protein turnover during metabolic arrest in turtle hepatocytes: Role and energy dependence of proteolysis
45. A heme protein-based oxygen-sensing mechanism controls the expression and suppression of multiple proteins in anoxia-tolerant turtle hepatocytes
46. Response of protein synthesis to anoxia and recovery in anoxia-tolerant hepatocyte
47. The effects of biogenic stress and redox balance on the expression of genes critical to mitochondrial function
48. The role of mitochondria in the salvage and the injury of the ischemic myocardium
49. Mechanisms for anoxic survival in the anoxic vertebrate brain
50. A receptor during anoxia in the turtle brain
51. Maintenance of adenosine A1 receptor function during long-term anoxia in the turtle brain
52. Diverse strategies for anoxic brain survival - Glycolysis on or off
53. Strategies for dealing with variations in gas tensions - Vertebrates and invertebrates
54. Living without oxygen: Turtle brain as a model of anaerobic metabolism
55. Cerebral resistance to anoxia in the marine turtle
56. Inducible operation of the erythropoietin 3′ enhancer in multiple cell lines: Evidence for a widespread oxygen-sensing mechanism
57. Low extracellular dopamine levels are maintained in the anoxic turtle brain
58. The diving response and its surprising evolutionary path in seals and sea lions
59. Hypoxic coordinate regulation of mitochondrial enzymes in mammalian cells
60. The identification of heme oxygenase as a major hypoxic stress protein in Chinese hamster ovary cells
61. Neurotransmitters and anoxia resistance: Comparative physiological and evolutionary perspectives
62. Role for adenosine in 'channel arrest' in the anoxic turtle brain
63. +-ATP channel activation provides transient protection in anoxic turtle brain
64. Down-regulation of sodium channels during anoxia: A putative survival strategy of turtle brain
65. 2
66. High levels of ascorbic acid, not glutathione, in the CNS of anoxia-tolerant reptiles contrasted with levels in anoxia-intolerant species
67. Coordinate regulation of glycolysis by hypoxia in mammalian cells
68. Regulation of the mitochondrial ATPase in situ in cardiac muscle: Role of the inhibitor subunit
69. Nuclear respiratory factors and the pathways of nuclear-mitochondrial interactions
70. Nuclear control of respiratory chaine expression in mammalian cells
71. The Pasteur effect in facultative anaerobic metazoa
72. Hypoxia response elements in the aldolase A, enolase 1, and lactate dehydrogenase A gene promoters contain essential binding sites for hypoxia-inducible factor-1
73. Tests of turtle phylogeny: Molecular, morphological, and paleontological approaches
74. Maintaining coupled metabolism and membrane function in anoxic brain: A comparison between the turtle and rat
75. Characterization of a hypoxia-inducible factor (HIF-1 alpha) from rainbow trout - Accumulation of protein occurs at normal venous oxygen tension
76. Mitochondria as ATP consumers: Cellular treason in anoxia
77. Metabolic rate depression and biochemical adaptation in anaerobiosis, hibernation, and estivation
78. Ecology and physiology of hibernation and overwintering among freshwater fishes, turtles, and snakes
79. The physiology of hibernation among painted turtles: The eastern painted turtle, Chrysemys picta picta
80. Surviving low oxygen levels: Lessons from fishes of the Amazon
81. Assessment of translational regulation by run-off translation of polysomes in vitro
82. Structural effects of intracellular amino acids during ATP depletion
83. Hypoxia-inducible factor 1 is a basic helix-loop-helix PAS heterodimer regulated by cellular oxygen tension
84. Regulation of tissue-specific isozyme genes: Coordinate response to oxygen availability in myogenic cells
85. Coordinate reciprocal trends in glycolytic and mitochondrial transcript accumulations during the in vitro differentiation of human myoblasts
86. Induction and nuclear accumulation of fos and jun proto-oncogenes in hypoxia cardiac myocytes
87. Regulation of fos and jun immediate-early genes by redox or metabolic stress in cardiac myocytes
88. A glycolytic pathway to apoptosis of hypoxic cardiac myocytes
89. Oxygen(es) and the hypoxia-inducible factor 1
90. Electrical stimulation of neonatal cardiomyocytes results in the sequential activation of nuclear genes governing mitochondrial proliferation and differentiation
91. How Do Cells Sense Oxygen?