Expression of HSP 70 as a potential prognostic marker for acute rejection in human liver transplantation

Transplant International

Volumn 11, Issue 2, 1998, Pages 89-94

  Flohé, Sascha ^a   Speidel, Nicola ^a   Flach, Regina ^a   Lange, Reinhard ^a   Erhard, Jochen ^a   Schade, F Ulrich ^a  

^a UNIVERSITY HOSPITAL ESSEN   (Germany)

Author keywords

Heat shock protein 70, acute rejection, liver transplantation Rejection, acute, heat shock protein 70; Livertransplantation, heat shock protein 70, rejection, cold preservation; PCR

Indexed keywords

HEAT SHOCK PROTEIN 70; MARKER; MESSENGER RNA;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; EARLY DIAGNOSIS; GRAFT REJECTION; HUMAN; HUMAN TISSUE; LIVER BIOPSY; LIVER PRESERVATION; LIVER TRANSPLANTATION; MESSENGER RNA SYNTHESIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; RETROSPECTIVE STUDY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADULT; BIOLOGICAL MARKERS; BIOPSY; FEMALE; GRAFT REJECTION; HSP70 HEAT-SHOCK PROTEINS; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; LIVER TRANSPLANTATION; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; PROGNOSIS; RNA, MESSENGER;

EID: 0031914064     PISSN: 09340874     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001470050110     Document Type: Article

References (21)

1. Bishop GA, Rokahr KL, Napoli J, McCaughan GW (1993) Intragraft cytokine mRNA levels in human liver allograft rejection analyzed by reverse transcription and semiquantitative polymerase chain reaction amplification. Transpl Immunol 1: 253-261
2. Colletti LM, Remick DG, Burtch GD, Kunkel SL, Stricter RM, Campbell DA Jr (1990) Role of tumor necrosis factor-alpha in the pathophysiologic alterations after hepatic ischemia/reperfusion injury in the rat. J Clin Invest 85: 1936-1943
3. Currie RW, Tanguay RM, Kingma JG Jr (1993) Heat-shock response and limitation of tissue necrosis during occlusion/ reperfusion in rabbit hearts Circulation 87: 963-971
4. Dworniczak B, Mirault ME (1987) Structure and expression of a human gene coding for a 71 kD heat shock "cognate" protein. Nucleic Acids Res 15: 5181-5197
5. Geiger T, Andus T, Klapproth J, Hirano T, Kishimoto T, Heinrich PC (1988) Induction of rat acute-phase proteins by interleukin 6 in vivo. Eur J Immunol 18: 717-721
6. Howard TK, Klintmalm GB, Cofer JB, Husberg BS, Goldstein RM, Gonwa TA (1990) The influence of preservation injury on rejection in the hepatic transplant recipient. Transplantation 49: 103-107
7. Hutter MM, Sievers RE, Barbosa V, Wolfe CL (1994) Heat-shock protein induction in rat hearts. A direct correlation between the amount of heat-shock protein induced and the degree of myocardial protection. Circulation 89: 355-360
8. Kemnitz J (1991) The histopathological classification of liver allograft rejection. In: Engemann R, Hamelmann H (eds) Experimental and clinical liver transplantation. Elsevier, Amsterdam, New York. Oxford, pp 9-14
9. Le Moine O, Marchant A, Durand F, Ickx B, Pradier O, Belghiti J, Abramowicz D, Gelin M, Goldman M, Deviere J (1994) Systemic release of interleukin-10 during orthotopk liver transplantation. Hepatology 20: 889-892
10. Marber MS, Mestril R, Chi SH, Sayen MR, Yellon DM, Dillmann WH (1995) Overexpression of the rat inducible 70-kD heat stress protein in a transgenic mouse increases the resistance of the heart to ischemic injury. J Clin Invest 95: 1446-1456
11. McCurry KR, Campbell DA Jr, Scales WE, Warren JS, Remick DG (1993) Tumor necrosis factor, interleukin 6, and the acute phase response following hepatic ischemia/reperfusion. J Surg Res 55: 49-54
12. Myrmel T, McCully JD, Malikin L, Krukenkamp IB, Levitsky S (1994) Heat-shock protein 70 mRNA is induced by anaerobic metabolism in rat hearts. Circulation 90: 299-305
13. Ohzato H, Monden M, Yoshizaki K, Gotoh M, Kanai T, Umeshita K, Tono T, Nishimoto N, Kishimoto T, Mori T (1993) Serum interleukin-6 levels as an indicator of acute rejection after liver transplantation in cynomologous monkeys. Surg Today 23: 521-527
14. Schiaffonati L, Cairo G, Tacchini L, Pappalardo C, Gatti S, Piazzini Albani A, Bernelli Zazzera A (1993) Protein synthesis and gene expression in transplanted and postischemic livers. Transplantation 55: 977-982
15. Schmid J, Weissman C (1987) Induction of mRNA for a serine protease and a beta-thromboglobulin like protein in mitogen stimulated human leukocytes, J Immunol 139: 250-257
16. Sun JZ, Tang XL, Knowlton AA, Park SW, Qiu Y, Bolii R (1995) Late preconditioning against myocardial stunning. An endogenous protective mechanism that confers resistance to postischemic dysfunction 24 h after brief ischemia in conscious pigs. J Clin Invest 95: 388-403
17. Tacchini L, Pogliaghi G, Radice L, Anzon E, Bernelli Zazzera A (1995) Differential activation of heat-shock and oxidation-specific stress genes in chemically induced oxidative stress. Biochem J 309: 453-459
18. Tilg H, Ceska M, Vogel W, Herold M, Margreiter R, Huber C (1992) Interleukin-8 serum concentrations after liver transplantation. Transplantation 53: 800-803
19. Umeshita K, Monden M, Tono T, Hasuike Y, Kanai T, Gotoh M, Mon T, Seu P, Shaked A, Busuttil RW (1992) Interleukin-6 in bile as a marker of allograft rejection following liver transplantation in man. Transplant Proc 24: 1462-1464
20. Zhang YH, Takahashi K, Jiang GZ, Zhang XM, Kawai M, Fukada M, Yokochi T (1994) In vivo production of heat shock protein in mouse peritoneal macrophages by administration of lipopolysaccharide. Infect Immun 62: 4140-4144
21. Zilberstein A, Ruggieri R, Korn JH, Revel M (1986) Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines. EMBO J 5: 2529-2537