D-ring substituted 1,2,3-triazolyl 20-keto pregnenanes as potential anticancer agents: Synthesis and biological evaluation

Steroids

Volumn 75, Issue 12, 2010, Pages 801-804

  Banday, Abid H ^a,b   Shameem, Shameem A ^a   Gupta, B D ^b   Kumar, H M Sampath ^b  

^a Islamia College of Science and Commerce   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

Author keywords

Click chemistry; Pregnenolone; Triazoles

Indexed keywords

1 (3 HYDROXY 10,13 DIMETHYL 2,3,4,7,8,9,10,11,12,13,14,15,16,17 TETRADECAHYD RO 1H CYCLOPENTA[A]PHENANTHREN 17 YL) 2 (4 PHENOXYMETHYL[1,2,3]TRIAZOL 1 YL)ETHANONE; 2 [4 (3 CHLORO PHENOXY) [1,2,3]TRIAZOL 1 YL] 1 (3 HYDROXY 10 13 DIMETHYL 2,3,4,7,8,9,10,11,12,13,14,15,16,17 TETRADECAHYDRO 1H CYCLOPENTA[A]PHENANTHREN 17 YL)ETHANONE; 2 [4 (4 ACETYL PHENOXY) [1,2,3]TRIAZOL 1 YL] 1 (3 HYDROXY 10 13 DIMETHYL 2,3,4,7,8,9,10,11,12,13,14,15,16,17 TETRADECAHYDRO 1H CYCLOPENTA[A]PHENANTHREN 17 YL)ETHANONE; ANTINEOPLASTIC AGENT; PREGNENOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CENTRAL NERVOUS SYSTEM TUMOR; COLON CANCER; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; LIVER CANCER; LUNG CANCER; MELTING POINT; ONE POT SYNTHESIS; PROSTATE CANCER;

ACETYLENE; ANTINEOPLASTIC AGENTS; AZIDES; CATALYSIS; CELL LINE, TUMOR; COPPER; HUMANS; INHIBITORY CONCENTRATION 50; PREGNENES; STEREOISOMERISM; SUBSTRATE SPECIFICITY; TRIAZOLES;

EID: 77955926541     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2010.02.015     Document Type: Article

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