메뉴 건너뛰기




Volumn 13, Issue 5, 2010, Pages 574-581

Polymyxins and their novel derivatives

Author keywords

[No Author keywords available]

Indexed keywords

CB 182804; CLARITHROMYCIN; COLISTIN; NAB 7061; NAB 739; NAB 740; NAB 741; NAB 752; POLYMYXIN B; POLYMYXIN DERIVATIVE; RIFAMPICIN; UNCLASSIFIED DRUG;

EID: 77957816982     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mib.2010.09.002     Document Type: Review
Times cited : (83)

References (66)
  • 2
    • 59449088862 scopus 로고    scopus 로고
    • Antibiotic-resistant bugs in the 21st century-a clinical super-challenge
    • Arias C.A., Murray B.E. Antibiotic-resistant bugs in the 21st century-a clinical super-challenge. New Engl J Med 2009, 360:439-443.
    • (2009) New Engl J Med , vol.360 , pp. 439-443
    • Arias, C.A.1    Murray, B.E.2
  • 3
    • 36448983944 scopus 로고    scopus 로고
    • Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review
    • Zawascki A.P., Goldani L.Z., Li J., Nation R.L. Polymyxin B for the treatment of multidrug-resistant pathogens: a critical review. J Antibiot Chemother 2007, 60:1206-1215.
    • (2007) J Antibiot Chemother , vol.60 , pp. 1206-1215
    • Zawascki, A.P.1    Goldani, L.Z.2    Li, J.3    Nation, R.L.4
  • 5
    • 70350528719 scopus 로고    scopus 로고
    • Colistin in the 21st century
    • Nation R.L., Li J. Colistin in the 21st century. Curr Opin Infect Dis 2009, 22:535-543.
    • (2009) Curr Opin Infect Dis , vol.22 , pp. 535-543
    • Nation, R.L.1    Li, J.2
  • 6
    • 33845903833 scopus 로고    scopus 로고
    • Drugs for bad bugs: confronting the challenges of antibacterial discovery
    • Payne D.J., Gwynn M.N., Holmes D.J., Pompliano D.L. Drugs for bad bugs: confronting the challenges of antibacterial discovery. Nat Rev 2007, 6:29-40.
    • (2007) Nat Rev , vol.6 , pp. 29-40
    • Payne, D.J.1    Gwynn, M.N.2    Holmes, D.J.3    Pompliano, D.L.4
  • 8
    • 69949174478 scopus 로고    scopus 로고
    • Has the era of untreatable infections arrived?
    • Livermore D. Has the era of untreatable infections arrived?. J Antimicrob Chemother 2009, 64(Suppl. 1):i29-i36.
    • (2009) J Antimicrob Chemother , vol.64 , Issue.SUPPL. 1
    • Livermore, D.1
  • 9
    • 77952298917 scopus 로고    scopus 로고
    • Hospital-acquired infections due to Gram-negative bacteria
    • Peleg A.Y., Hooper D.C. Hospital-acquired infections due to Gram-negative bacteria. New Engl J Med 2010, 362:1804-1813.
    • (2010) New Engl J Med , vol.362 , pp. 1804-1813
    • Peleg, A.Y.1    Hooper, D.C.2
  • 10
    • 77955917495 scopus 로고    scopus 로고
    • Emergence of a new antibiotic resistance mechanism in India, Pakistan and the UK: a molecular, biological, and epidemiological study
    • published online August 11, 2010
    • Kumarasamy K.K., Toleman M.A., Walsh T., Bagaria J., Butt F., Balakrishnan R., Chaudhary U., Doumith M., Giske c.G., Irfan S., et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan and the UK: a molecular, biological, and epidemiological study. Lancet Infect Dis 2010, published online August 11, 2010. 10.1016/S1473-3099(10)70143-2.
    • (2010) Lancet Infect Dis
    • Kumarasamy, K.K.1    Toleman, M.A.2    Walsh, T.3    Bagaria, J.4    Butt, F.5    Balakrishnan, R.6    Chaudhary, U.7    Doumith, M.8    Giske, C.9    Irfan, S.10
  • 11
    • 74549179120 scopus 로고    scopus 로고
    • The emerging threat of acquired carbapenemases in Gram-negative bacteria
    • Cornaglia G., Rossolini G.M. The emerging threat of acquired carbapenemases in Gram-negative bacteria. Clin Microbiol Infect 2010, 16:99-101.
    • (2010) Clin Microbiol Infect , vol.16 , pp. 99-101
    • Cornaglia, G.1    Rossolini, G.M.2
  • 13
    • 42949084616 scopus 로고    scopus 로고
    • Detection of methyltransferases conferring high-level resistance to aminoglycosides in Enterobacteriaceae from Europe, North America, and Latin America
    • Fritsche T.R., Castanheira M., Miller G.H., Jones R.N., Armstrong E.S. Detection of methyltransferases conferring high-level resistance to aminoglycosides in Enterobacteriaceae from Europe, North America, and Latin America. Antimicrob Agents Chemother 2008, 52:1843-1845.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1843-1845
    • Fritsche, T.R.1    Castanheira, M.2    Miller, G.H.3    Jones, R.N.4    Armstrong, E.S.5
  • 14
    • 77957782230 scopus 로고    scopus 로고
    • Activity of ACHN-490 and other aminoglycosides vs. carbapenem-resistant Enterobacteriaceae isolated in the United Kingdom
    • Mushtaq S., Warner M., Zhang J.-C., Maharjan S., Doumith M., Woodford N., Livermore D. Activity of ACHN-490 and other aminoglycosides vs. carbapenem-resistant Enterobacteriaceae isolated in the United Kingdom. Clin Microbiol Infect 2010, 16(Suppl. 2):S85.
    • (2010) Clin Microbiol Infect , vol.16 , Issue.SUPPL. 2
    • Mushtaq, S.1    Warner, M.2    Zhang, J.-C.3    Maharjan, S.4    Doumith, M.5    Woodford, N.6    Livermore, D.7
  • 15
    • 70349751622 scopus 로고    scopus 로고
    • Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update
    • Blair J.M.A., Piddock L.J.V. Structure, function and inhibition of RND efflux pumps in Gram-negative bacteria: an update. Curr Opin Microbiol 2009, 12:512-519.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 512-519
    • Blair, J.M.A.1    Piddock, L.J.V.2
  • 17
    • 74249108028 scopus 로고    scopus 로고
    • Three decades of β-lactamase inhibitors
    • Drawz S.M., Bonomo R.A. Three decades of β-lactamase inhibitors. Clin Microbiol Rev 2010, 23:160-201.
    • (2010) Clin Microbiol Rev , vol.23 , pp. 160-201
    • Drawz, S.M.1    Bonomo, R.A.2
  • 18
    • 77952614275 scopus 로고    scopus 로고
    • In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant Gram-negative bacilli
    • Page M.G.P., Dantier C., Desarbre E. In vitro properties of BAL30072, a novel siderophore sulfactam with activity against multiresistant Gram-negative bacilli. Antimicrob Agents Chemother 2010, 54:2291-2302.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 2291-2302
    • Page, M.G.P.1    Dantier, C.2    Desarbre, E.3
  • 21
    • 34447560960 scopus 로고    scopus 로고
    • Toxicity of polymyxins: a systematic review of the evidence from old and recent studies
    • Falagas M.E., Kasiakou S.K. Toxicity of polymyxins: a systematic review of the evidence from old and recent studies. Crit Care 2006, 10:R27.
    • (2006) Crit Care , vol.10
    • Falagas, M.E.1    Kasiakou, S.K.2
  • 23
    • 0026802197 scopus 로고
    • Agents that increase the permeability of the outer membrane
    • Vaara M. Agents that increase the permeability of the outer membrane. Microbiol Rev 1992, 56:395-411.
    • (1992) Microbiol Rev , vol.56 , pp. 395-411
    • Vaara, M.1
  • 24
    • 0040777048 scopus 로고    scopus 로고
    • The functional association of polymyxin B with bacterial lipopolysaccharide is stereospecific: studies on polymyxin B nonapeptide
    • Tsubery H., Ofek I., Cohen S., Fridkin M. The functional association of polymyxin B with bacterial lipopolysaccharide is stereospecific: studies on polymyxin B nonapeptide. Biochemistry 2000, 39:11838-11844.
    • (2000) Biochemistry , vol.39 , pp. 11838-11844
    • Tsubery, H.1    Ofek, I.2    Cohen, S.3    Fridkin, M.4
  • 26
    • 50249139019 scopus 로고    scopus 로고
    • Parenteral polymyxin B use in patients with multidrug-resistant Gram-negative bacteremia and urinary tract infections: a retrospective case series
    • Pastewski A.A., Caruso P., Parris A.R., Dizon R., Kopec R., Sharma S., Mayer S., Ghitan M., Chapnick E.K. Parenteral polymyxin B use in patients with multidrug-resistant Gram-negative bacteremia and urinary tract infections: a retrospective case series. Ann Pharmacother 2008, 42:1177-1187.
    • (2008) Ann Pharmacother , vol.42 , pp. 1177-1187
    • Pastewski, A.A.1    Caruso, P.2    Parris, A.R.3    Dizon, R.4    Kopec, R.5    Sharma, S.6    Mayer, S.7    Ghitan, M.8    Chapnick, E.K.9
  • 28
    • 66949120361 scopus 로고    scopus 로고
    • Nephrotoxicity of colistin: new insight into an old antibiotic
    • Falagas M.E., Rafailidis P.I. Nephrotoxicity of colistin: new insight into an old antibiotic. Clin Infect Dis 2009, 48:1729-1731.
    • (2009) Clin Infect Dis , vol.48 , pp. 1729-1731
    • Falagas, M.E.1    Rafailidis, P.I.2
  • 29
    • 4744348954 scopus 로고    scopus 로고
    • Molecular aspects of renal handling of aminoglycosides and strategies for preventing the nephrotoxicity
    • Nagai J., Takano M. Molecular aspects of renal handling of aminoglycosides and strategies for preventing the nephrotoxicity. Drug Metab Pharmacokin 2004, 19:159-170.
    • (2004) Drug Metab Pharmacokin , vol.19 , pp. 159-170
    • Nagai, J.1    Takano, M.2
  • 33
    • 77953706297 scopus 로고    scopus 로고
    • Susceptibility of carbapenemase-producing strains of Klebsiella pneumoniae and Escherichia coli to the direct antibacterial activity of NAB739 and to the synergistic activity of NAB7061 with rifampin and clarithromycin
    • Vaara M., Siikanen O., Apajalahti J., Frimodt-Møller N., Vaara T. Susceptibility of carbapenemase-producing strains of Klebsiella pneumoniae and Escherichia coli to the direct antibacterial activity of NAB739 and to the synergistic activity of NAB7061 with rifampin and clarithromycin. J Antimicrob Chemother 2010, 65:942-945.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 942-945
    • Vaara, M.1    Siikanen, O.2    Apajalahti, J.3    Frimodt-Møller, N.4    Vaara, T.5
  • 34
    • 77953707737 scopus 로고    scopus 로고
    • Novel polymyxin derivatives are effective in treating experimental Escherichia coli peritoneal infection in mice
    • Vingsbo Lundberg C., Vaara T., Frimodt-Møller N., Vaara M. Novel polymyxin derivatives are effective in treating experimental Escherichia coli peritoneal infection in mice. J Antimicrob Chemother 2010, 65:981-985.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 981-985
    • Vingsbo Lundberg, C.1    Vaara, T.2    Frimodt-Møller, N.3    Vaara, M.4
  • 35
    • 77955345521 scopus 로고    scopus 로고
    • A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane
    • Vaara M., Siikanen O., Apajalahti J., Fox J., Frimodt-Moeller J., He H., Poydyal A., Li J., Nation R.L., Vaara T. A novel polymyxin derivative that lacks the fatty acid tail and carries only three positive charges has strong synergism with agents excluded by the intact outer membrane. Antimicrob Agents Chemother 2010, 54:3341-3346.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 3341-3346
    • Vaara, M.1    Siikanen, O.2    Apajalahti, J.3    Fox, J.4    Frimodt-Moeller, J.5    He, H.6    Poydyal, A.7    Li, J.8    Nation, R.L.9    Vaara, T.10
  • 36
    • 0034817854 scopus 로고    scopus 로고
    • N-terminal modifications of polymyxin B nonapeptide and their effect on antibacterial activity
    • Tsubery H., Ofek I., Cohen S., Fridkin M. N-terminal modifications of polymyxin B nonapeptide and their effect on antibacterial activity. Peptides 2001, 22:1675-1681.
    • (2001) Peptides , vol.22 , pp. 1675-1681
    • Tsubery, H.1    Ofek, I.2    Cohen, S.3    Fridkin, M.4
  • 37
    • 73949154997 scopus 로고    scopus 로고
    • Pharmacokinetics of novel antimicrobial cationic peptides NAB7061 and NAB739 in rats following intravenous administration
    • Ali F.E., Cao G., Poydal A., Vaara T., Nation R.L., Vaara M., Li J. Pharmacokinetics of novel antimicrobial cationic peptides NAB7061 and NAB739 in rats following intravenous administration. J Antimicrob Chemother 2009, 64:1067-1070.
    • (2009) J Antimicrob Chemother , vol.64 , pp. 1067-1070
    • Ali, F.E.1    Cao, G.2    Poydal, A.3    Vaara, T.4    Nation, R.L.5    Vaara, M.6    Li, J.7
  • 38
    • 77957781502 scopus 로고    scopus 로고
    • U.S. Patent Application Publication US2008/0287345.
    • Vaara M, Vaara T: U.S. Patent Application Publication US2008/0287345.
    • Vaara, M.1    Vaara, T.2
  • 39
    • 0021246002 scopus 로고
    • An outer membrane-disorganizing peptide PMBN sensitizes E. coli strains to serum bactericidal action
    • Vaara M., Viljanen P., Vaara T., Mäkelä P. An outer membrane-disorganizing peptide PMBN sensitizes E. coli strains to serum bactericidal action. J Immunol 1984, 132:2582-2589.
    • (1984) J Immunol , vol.132 , pp. 2582-2589
    • Vaara, M.1    Viljanen, P.2    Vaara, T.3    Mäkelä, P.4
  • 40
    • 0033929412 scopus 로고    scopus 로고
    • Targeting lipopolysaccharides by the nontoxic polymyxin B nonapeptide sensitizes resistant Escherichia coli to the bactericidal effect of human neutrophils
    • Rose F., Heuer K.U., Sibelius U., Hombach-Klonisch S., Kiss L., Seeger W., Grimminger F. Targeting lipopolysaccharides by the nontoxic polymyxin B nonapeptide sensitizes resistant Escherichia coli to the bactericidal effect of human neutrophils. J Infect Dis 2000, 182:191-199.
    • (2000) J Infect Dis , vol.182 , pp. 191-199
    • Rose, F.1    Heuer, K.U.2    Sibelius, U.3    Hombach-Klonisch, S.4    Kiss, L.5    Seeger, W.6    Grimminger, F.7
  • 41
  • 42
    • 70349496543 scopus 로고    scopus 로고
    • New approaches in peptide antibiotics
    • Vaara M. New approaches in peptide antibiotics. Curr Opin Pharmacol 2009, 9:571-576.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 571-576
    • Vaara, M.1
  • 43
    • 0018365677 scopus 로고
    • Decreased binding of polymyxin by polymyxin-resistant mutants of Salmonella typhimurium
    • Vaara M., Vaara T., Sarvas M. Decreased binding of polymyxin by polymyxin-resistant mutants of Salmonella typhimurium. J Bacteriol 1979, 139:664-667.
    • (1979) J Bacteriol , vol.139 , pp. 664-667
    • Vaara, M.1    Vaara, T.2    Sarvas, M.3
  • 44
    • 77949346087 scopus 로고    scopus 로고
    • Structure-activity relationships of polymyxin antibiotics
    • Velkov T., Thompson P.E., Nation R.L., Li J. Structure-activity relationships of polymyxin antibiotics. J Med Chem 2010, 53:1898-1916.
    • (2010) J Med Chem , vol.53 , pp. 1898-1916
    • Velkov, T.1    Thompson, P.E.2    Nation, R.L.3    Li, J.4
  • 46
    • 65349101100 scopus 로고    scopus 로고
    • Development of des-fatty acyl-polymyxin B decapeptide analogs with Pseudomonas aeruginosa-specific antimicrobial activity
    • Katsuma N., Sato Y., Ohki K., Okimura K., Ohnishi K., Sakura N. Development of des-fatty acyl-polymyxin B decapeptide analogs with Pseudomonas aeruginosa-specific antimicrobial activity. Chem Pharm Bull 2009, 57:332-336.
    • (2009) Chem Pharm Bull , vol.57 , pp. 332-336
    • Katsuma, N.1    Sato, Y.2    Ohki, K.3    Okimura, K.4    Ohnishi, K.5    Sakura, N.6
  • 47
    • 76649119425 scopus 로고    scopus 로고
    • Structure-activity relationships of bacterial outer-membrane permeabilizers based on polymyxin B heptapeptides
    • Urakawa H., Yamada K., Komagoe K., Ando S., Oku H., Katsu T., Matsuo I. Structure-activity relationships of bacterial outer-membrane permeabilizers based on polymyxin B heptapeptides. Bioorg Med Chem Lett 2010, 20:1771-1775.
    • (2010) Bioorg Med Chem Lett , vol.20 , pp. 1771-1775
    • Urakawa, H.1    Yamada, K.2    Komagoe, K.3    Ando, S.4    Oku, H.5    Katsu, T.6    Matsuo, I.7
  • 51
    • 70350279543 scopus 로고    scopus 로고
    • In vitro activity of colistin (polymyxin E) against 3,480 isolates of Gram-negative bacilli obtained from patients in Canadian hospitals in the CANWARD study, 2007-2008
    • Walkty A., DeCorby M., Nichol K., Karlowsky J.A., Hoban D.J., Zhanel G.G. In vitro activity of colistin (polymyxin E) against 3,480 isolates of Gram-negative bacilli obtained from patients in Canadian hospitals in the CANWARD study, 2007-2008. Antimicrob Agents Chemother 2009, 53:4924-4926.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 4924-4926
    • Walkty, A.1    DeCorby, M.2    Nichol, K.3    Karlowsky, J.A.4    Hoban, D.J.5    Zhanel, G.G.6
  • 52
    • 84879282675 scopus 로고
    • Characterization of the lipopolysaccharide from the polymyxin-resistant pmrA mutants of Salmonella typhimurium
    • Vaara M., Vaara T., Jensen M., Helander I., Nurminen M., Rietschel E., Mäkelä P. Characterization of the lipopolysaccharide from the polymyxin-resistant pmrA mutants of Salmonella typhimurium. FEBS Lett 1981, 129:145-149.
    • (1981) FEBS Lett , vol.129 , pp. 145-149
    • Vaara, M.1    Vaara, T.2    Jensen, M.3    Helander, I.4    Nurminen, M.5    Rietschel, E.6    Mäkelä, P.7
  • 53
    • 0028263473 scopus 로고
    • Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR study
    • Helander I., Kilpeläinen I., Vaara M. Increased substitution of phosphate groups in lipopolysaccharides and lipid A of the polymyxin-resistant pmrA mutants of Salmonella typhimurium: a 31P-NMR study. Mol Microbiol 1994, 11:481-487.
    • (1994) Mol Microbiol , vol.11 , pp. 481-487
    • Helander, I.1    Kilpeläinen, I.2    Vaara, M.3
  • 54
    • 0029010091 scopus 로고
    • Lipopolysaccharides of polymyxin B-resistant mutants of Escherichia coli are extensively substituted by 2-aminoethyl pyrophosphate and contain aminoarabinose in lipid A
    • Nummila K., Kilpeläinen I., Zähringer U., Vaara M., Helander I. Lipopolysaccharides of polymyxin B-resistant mutants of Escherichia coli are extensively substituted by 2-aminoethyl pyrophosphate and contain aminoarabinose in lipid A. Mol Microbiol 1995, 16:271-278.
    • (1995) Mol Microbiol , vol.16 , pp. 271-278
    • Nummila, K.1    Kilpeläinen, I.2    Zähringer, U.3    Vaara, M.4    Helander, I.5
  • 56
    • 0033584935 scopus 로고    scopus 로고
    • Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa
    • Ernst R.K., Yi E.C., Guo L., Lim K.B., Burns J.L., Hackett M., Miller S.I. Specific lipopolysaccharide found in cystic fibrosis airway Pseudomonas aeruginosa. Science 1999, 286:1561-1565.
    • (1999) Science , vol.286 , pp. 1561-1565
    • Ernst, R.K.1    Yi, E.C.2    Guo, L.3    Lim, K.B.4    Burns, J.L.5    Hackett, M.6    Miller, S.I.7
  • 57
    • 0346655236 scopus 로고    scopus 로고
    • PmrA, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A
    • Moskowitz S.M., Ernst R.K., Miller S.I. PmrA, a two-component regulatory system of Pseudomonas aeruginosa that modulates resistance to cationic antimicrobial peptides and addition of aminoarabinose to lipid A. J Bacteriol 2004, 186:575-579.
    • (2004) J Bacteriol , vol.186 , pp. 575-579
    • Moskowitz, S.M.1    Ernst, R.K.2    Miller, S.I.3
  • 59
    • 44649203366 scopus 로고    scopus 로고
    • The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more
    • Gunn J.S. The Salmonella PmrAB regulon: lipopolysaccharide modifications, antimicrobial peptide resistance and more. Trends Microbiol 2008, 16:284-290.
    • (2008) Trends Microbiol , vol.16 , pp. 284-290
    • Gunn, J.S.1
  • 60
    • 66149088136 scopus 로고    scopus 로고
    • Decreased susceptibility to polymyxin B during treatment for carbapenem-resistant Klebsiella pneumoniae infection
    • Lee J., Patel G., Huprikar S., Calfee D.P., Jenkins S.G. Decreased susceptibility to polymyxin B during treatment for carbapenem-resistant Klebsiella pneumoniae infection. Antimicrob Agents Chemother 2009, 47:1611-1612.
    • (2009) Antimicrob Agents Chemother , vol.47 , pp. 1611-1612
    • Lee, J.1    Patel, G.2    Huprikar, S.3    Calfee, D.P.4    Jenkins, S.G.5
  • 62
    • 0019855368 scopus 로고
    • Increased outer membrane resistance to ethylenediamine tetraacetate and cations in novel lipid A mutants
    • Vaara M. Increased outer membrane resistance to ethylenediamine tetraacetate and cations in novel lipid A mutants. J Bacteriol 1981, 148:426-434.
    • (1981) J Bacteriol , vol.148 , pp. 426-434
    • Vaara, M.1
  • 63
    • 31344459012 scopus 로고    scopus 로고
    • A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid
    • Froelich J.M., Tran K., Wall D. A pmrA constitutive mutant sensitizes Escherichia coli to deoxycholic acid. J Bacteriol 2006, 188:1180-1183.
    • (2006) J Bacteriol , vol.188 , pp. 1180-1183
    • Froelich, J.M.1    Tran, K.2    Wall, D.3
  • 64
    • 34548273967 scopus 로고    scopus 로고
    • Antibiograms of multidrug-resistant clinical Acinetobacter baumannii: promising therapeutic options for treatment of infection with colistin-resistant strains
    • Li J., Nation R.L., Owen R.J., Wong S., Spelman D., Franklin C. Antibiograms of multidrug-resistant clinical Acinetobacter baumannii: promising therapeutic options for treatment of infection with colistin-resistant strains. Clin Infect Dis 2007, 45:594-598.
    • (2007) Clin Infect Dis , vol.45 , pp. 594-598
    • Li, J.1    Nation, R.L.2    Owen, R.J.3    Wong, S.4    Spelman, D.5    Franklin, C.6
  • 65
    • 35048828537 scopus 로고    scopus 로고
    • PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica Serovar Typhimurium
    • Murata T., Tseng W., Guina T., Miller S.I., Nikaido H. PhoPQ-mediated regulation produces a more robust permeability barrier in the outer membrane of Salmonella enterica Serovar Typhimurium. J Bacteriol 2007, 189:7213-7222.
    • (2007) J Bacteriol , vol.189 , pp. 7213-7222
    • Murata, T.1    Tseng, W.2    Guina, T.3    Miller, S.I.4    Nikaido, H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.