N-terminal modifications of Polymyxin B nonapeptide and their effect on antibacterial activity

Peptides

Volumn 22, Issue 10, 2001, Pages 1675-1681

  Tsubery, Haim ^a,b   Ofek, Itzhak ^b   Cohen, Sofia ^b   Fridkin, Mati ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

Antibacterial peptide; Lipopolysaccharide; Polymyxin B; Polymyxin B nonapeptide

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; NOVOBIOCIN; POLYMYXIN B NONAPEPTIDE; POLYMYXIN DERIVATIVE; POLYPEPTIDE ANTIBIOTIC AGENT;

AMINO TERMINAL SEQUENCE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL OUTER MEMBRANE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; DRUG PENETRATION; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; HYDROPHOBICITY; MALE; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; STRUCTURE ACTIVITY RELATION;

AMINO ACID MOTIFS; ANIMALS; ANTI-BACTERIAL AGENTS; BINDING SITES; CELLS, CULTURED; GRAM-NEGATIVE BACTERIA; INTERLEUKIN-6; LIPOPOLYSACCHARIDES; MALE; MICE; MICROBIAL SENSITIVITY TESTS; POLYMYXIN B; TUMOR NECROSIS FACTOR-ALPHA;

NEGIBACTERIA;

EID: 0034817854     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00503-4     Document Type: Article

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