Structural elements and allosteric mechanisms governing regulation and catalysis of CSK-family kinases and their inhibition of Src-family kinases

Growth Factors

Volumn 28, Issue 5, 2010, Pages 329-350

  Ia, Kim K ^a   Mills, Ryan D ^a   Hossain, Mohammed I ^a   Chan, Khai Chew ^a   Jarasrassamee, Boonyarin ^a   Jorissen, Robert N ^b   Cheng, Heung Chin ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b ROYAL MELBOURNE HOSPITAL   (Australia)

Author keywords

Allosteric regulation; Catalysis; CHK; CSK; Protein kinase; Src family kinases

Indexed keywords

ADENOSINE TRIPHOSPHATE; PEPTIDE YY; PROTEIN SH2; PROTEIN SH3; PROTEIN TYROSINE KINASE;

ALLOSTERISM; ALPHA HELIX; BINDING AFFINITY; BIOCATALYSIS; CHEMICAL ANALYSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; MOLECULAR EVOLUTION; MOLECULAR INTERACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN ISOLATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; CATALYSIS; HUMANS; MOLECULAR SEQUENCE DATA; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS; SRC-FAMILY KINASES; SUBSTRATE SPECIFICITY;

EID: 77957763100     PISSN: 08977194     EISSN: 10292292     Source Type: Journal    
DOI: 10.3109/08977194.2010.484424     Document Type: Review

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