Novel mechanism of regulation of the non-receptor protein tyrosine kinase Csk: Insights from NMR mapping studies and site-directed mutagenesis

Journal of Molecular Biology

Volumn 314, Issue 1, 2001, Pages 129-138

  Shekhtman, Alexander ^a   Ghose, Ranajeet ^a   Wang, Dongxia ^b   Cole, Philip A ^b   Cowburn, David ^a,c  

^a ROCKEFELLER UNIVERSITY   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NEW YORK STRUCTURAL BIOLOGY CENTER   (United States)

Author keywords

Heteronuclear NMR; Protein tyrosine kinase; SH3 domain; Src family kinases

Indexed keywords

PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE CSK; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME REGULATION; ENZYME STRUCTURE; GENE MAPPING; MULTIGENE FAMILY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTON NUCLEAR MAGNETIC RESONANCE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

EID: 0035900556     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2001.5126     Document Type: Article

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