Pharmacological inhibition of EGFR signaling enhances G-CSF-induced hematopoietic stem cell mobilization

Nature Medicine

Volumn 16, Issue 10, 2010, Pages 1141-1146

  Ryan, Marnie A ^a   Nattamai, Kalpana J ^a   Xing, Ellen ^a   Schleimer, David ^a   Daria, Deidre ^a,b   Sengupta, Amitava ^a   Köhler, Anja ^c   Liu, Wei ^a   Gunzer, Matthias ^c   Jansen, Michael ^a   Ratner, Nancy ^a   Le Cras, Timothy D ^d   Waterstrat, Amanda ^e   Van Zant, Gary ^f   Cancelas, Jose A ^a,g   Zheng, Yi ^a   Geiger, Hartmut ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF ULM   (Germany)

^c OTTO VON GUERICKE UNIVERSITY   (Germany)

^d CCHMC   (United States)

^e EASTERN KENTUCKY UNIVERSITY   (United States)

^f UNIVERSITY OF KENTUCKY   (United States)

^g UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; ALPHA5 INTEGRIN; BETACELLULIN; CD45 ANTIGEN; CELL SURFACE MARKER; CHEMOKINE RECEPTOR CXCR4; DIPEPTIDYL PEPTIDASE IV; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; ERLOTINIB; GRANULOCYTE COLONY STIMULATING FACTOR; HEPARIN BINDING EPIDERMAL GROWTH FACTOR; HERMES ANTIGEN; MESSENGER RNA; POLYINOSINIC POLYCYTIDYLIC ACID; PROTEIN CDC42; RAC1 PROTEIN; RAC2 PROTEIN; STROMAL CELL DERIVED FACTOR 1; SYNAPTOPHYSIN; TRANSFORMING GROWTH FACTOR ALPHA; VASCULAR CELL ADHESION MOLECULE 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW CELL; C57BL 6 MOUSE; CELL ADHESION; CELL CYCLE; CELL TRANSPLANTATION; CHIMERA; COLONY FORMING CELL; CONGENIC STRAIN; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; FLOW CYTOMETRY; GENE EXPRESSION; GENE MUTATION; HEMATOPOIETIC STEM CELL; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; KNOCKOUT MOUSE; MESENCHYMAL STEM CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STEM CELL MOBILIZATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; DBA MOUSE; PHYSIOLOGY;

ANIMALS; CDC42 GTP-BINDING PROTEIN; EPIDERMAL GROWTH FACTOR; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; MICE; MICE, INBRED C57BL; MICE, INBRED DBA; RECEPTOR, EPIDERMAL GROWTH FACTOR; SIGNAL TRANSDUCTION;

MUS;

EID: 77957762029     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm.2217     Document Type: Article

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