The transcription factor AP-1 is required for EGF-induced activation of Rho-like GTPases, cytoskeletal rearrangements, motility, and in vitro invasion of A431 cells

Journal of Cell Biology

Volumn 143, Issue 4, 1998, Pages 1087-1099

  Malliri, Angeliki ^a   Symons, Marc ^b,e   Hennigan, Robert F ^a,c   Hurlstone, Adam F L ^a   Lamb, Richard F ^a,d   Wheeler, Tricia ^a   Ozanne, Bradford W ^a  

^a BEATSON INSTITUTE FOR CANCER RESEARCH   (United Kingdom)

^b ONYX PHARMACEUTICALS   (United States)

^c UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

^e PICOWER INST FOR MEDICAL RESEARCH   (United States)

Author keywords

AP 1; EGFR; Invasion; Motility; Rho like GTPases

Indexed keywords

ACTIN; EPIDERMAL GROWTH FACTOR; GUANOSINE TRIPHOSPHATASE; RHO FACTOR; TRANSCRIPTION FACTOR AP 1;

ACTIN POLYMERIZATION; ARTICLE; CELL INVASION; CELL MOTILITY; CYTOSKELETON; DROSOPHILA; ENZYME ACTIVATION; GENE REARRANGEMENT; HUMAN; HUMAN CELL; MEMBRANE BINDING; PRIORITY JOURNAL; TRANSCRIPTION REGULATION;

ACTINS; CELL LINE, TRANSFORMED; CELL SIZE; CYTOSKELETON; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION; GTP PHOSPHOHYDROLASES; GTPASE-ACTIVATING PROTEINS; KERATINOCYTES; KIDNEY; MUTAGENESIS; PROTEINS; PROTO-ONCOGENE PROTEINS C-JUN; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSFECTION;

EID: 0032539001     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.143.4.1087     Document Type: Article

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