Adhesion of synchronized human hematopoietic progenitor cells to fibronectin and vascular cell adhesion molecule-1 fluctuates reversibly during cell cycle transit in ex vivo culture

Blood

Volumn 100, Issue 8, 2002, Pages 2744-2752

  Huygen, Sandra ^a,b   Giet, Olivier ^a,b   Artisien, Vincent ^a,b   Stefano, Ivano Di ^a,b   Beguin, Yves ^a,b   Gothot, André ^a,b  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b FUND FOR SCIENTIFIC RESEARCH   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA4 INTEGRIN; ALPHA5 INTEGRIN; CD34 ANTIGEN; FIBRONECTIN; LIGAND; NEUTRALIZING ANTIBODY; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BIOASSAY; CELL ADHESION; CELL CULTURE; CELL CYCLE; CELL CYCLE S PHASE; CELL MIGRATION; CELL SYNCHRONIZATION; CONTROLLED STUDY; HEMATOPOIESIS; HUMAN; HUMAN CELL; MITOGENESIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; STEM CELL; UMBILICAL CORD BLOOD;

EID: 0037108192     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.V100.8.2744     Document Type: Article

References (43)

1. Morrison SJ, Wright DE, Weissman IL. Cyclophosphamide/granulocyte colony-stimulating factor induces hematopoietic stem cells to proliferate prior to mobilization. Proc Natl Acad Sci U S A, 1997;94:1908-1913.
2. Wright DE, Cheshier SH, Wagers AJ, Randall TD, Christensen JL, Weissman IL. Cyclophosphamide/granulocyte colony-stimulating factor causes selective mobilization of bone marrow hematopoietic stem cells into the blood after M phase of the cell cycle. Blood. 2001;97:2278-2285.
3. Roberts AW, Metcalf D. Noncycling state of peripheral blood progenitor cells mobilized by granulocyte colony-stimulating factor and other cytokines. Blood. 1995;86:1600-1605.
4. Uchida N, He D, Friera A, et al. The unexpected G0/G1 cell cycle status of mobilized hematopoietic stem cells from the peripheral blood. Blood. 1997;89:465-472.
5. Gothot A, Pyatt R, McMahel J, Rice S, Srour EF, Functional heterogeneity of human CD34+ cells isolated in subcompartments of the G0/G1 phase of the cell cycle. Blood. 1997;90:4384-4393.
6. Gothot A, van der Loo JCM, Clapp DW, Srour EF, Cell cycle-related changes in repopulating capacity of human mobilized peripheral blood CD34+ cells in NOD/SCID mice. Blood. 1998;92:2641-2649.
7. Glimm H, Oh IH, Eaves CJ. Human hematopoietic stem cells stimulated to proliferate in vitro lose engraftment potential during their S/G(2)/M transit and do not reenter G(0). Blood. 2000;96: 4185-4193.
8. Habibian HK, Peters SO, Hsieh CC, et al. The fluctuating phenotype of the lymphohematopoietic stem cell with cell cycle transit. J Exp Med. 1998;188:393-398.
9. Nilsson SK, Debatis ME, Dooner MS, Madri JA, Quesenberry PJ, Becker PS. Immunofluorescence characterization of key extracellular matrix proteins in murine bone marrow in situ. J Histochem Cytochem. 1998;46:371-377.
10. Nilsson SK, Johnston HM, Coverdale JA. Spatial localization of transplanted hemopoietic stem cells: inferences for the localization of stem cell niches. Blood. 2001;97:2293-2299.
11. Williams DA, Rios M, Stephens C, Patel VP. Fibronectin and VLA-4 in haematopoietic stem cell-microenvironment interactions. Nature. 1991;352: 438-441.
12. Prosper F, Stroncek D, McCarthy JB, Verfaillie CM. Mobilization and homing of peripheral blood progenitors is related to reversible downregulation of α4β1 integrin expression and function. J Clin Invest. 1998;101:2456-2467.
13. van der Loo JC, Xiao X, McMillin D, Hashino K, Kato I, Williams DA. VLA-5 is expressed by mouse and human long-term repopulating hematopoietic cells and mediates adhesion to extracellular matrix protein fibronectin. J Clin Invest, 1998;102:1051-1061.
14. Peled A, Kollet O, Ponomaryov T, et al. The chemokine SDF-1 activates the integrins LFA-1, VLA-4, and VLA-5 on immature human CD34(+) cells: role in transendothelial/stromal migration and engraftment of NOD/SCID mice. Blood. 2000;95:3289-3296.
15. Jiang Y, Prosper F, Verfaillie CM, Opposing effects of engagement of integrins and stimulation of cytokine receptors on cell cycle progression of normal human hematopoietic progenitors. Blood. 2000;95:846-854.
16. Schofield KP, Humphries MJ, de Wynter E, Testa N, Gallagher JT. The effect of α4β1-integrin binding sequences of fibronectin on growth of cells from human hematopoietic progenitors. Blood. 1998;91:3230-3238.
17. Becker PS, Nilsson SK, Li Z, et al. Adhesion receptor expression by hematopoietic cell lines and murine progenitors: modulation by cytokines and cell cycle status. Exp Hematol. 1999;27:533-541.
18. Levesque JP, Leavesley DI, Niutta S, Vadas M, Simmons PJ. Cytokines increase human hematopoletic cell adhesiveness by activation of very late antigen (VLA)-4 and VLA-5 integrins. J Exp Med. 1995;181:1805-1815.
19. Kovach NL, Lin N, Yednock T, Harlan JM, Broudy VC. Stem cell factor modulates avidity of α 4 β 1 and α 5 β 1 integrins expressed on hematopoietic cell lines. Blood. 1995;85:159-167.
20. Cui L, Ramsfjell V, Borge OJ, Veiby OP, Lok S, Jacobsen SE. Thrombopoietin promotes adhesion of primitive human hemopoietic cells to fibronectin and vascular cell adhesion molecule-1: role of activation of very late antigen (VLA)-4 and VLA-5. J Immunol. 1997;159:1961-1969.
21. Giblin PA, Hwang ST, Katsumoto TR, Rosen SD. Ligation of L-selectin on T lymphocytes activates β1 integrins and promotes adhesion to fibronectin. J Immunol. 1997;159:3498-3507.
22. Lichterfeld M, Martin S, Burkly L, Haas R, Kronenwett R. Mobilization of CD34+ haematopoietic stem cells is associated with a functional inactivation of the integrin very late antigen 4. Br J Haematol. 2000;110:71-81.
23. Vermeulen M, Le Pesteur F, Gagnerault MC, Mary JY, Sainteny F, Lepault F. Role of adhesion molecules in the homing and mobilization of murine hematopoietic stem and progenitor cells. Blood. 1998;92:894-900.
24. Papayannopoulou T, Nakamoto B. Peripheralization of hemopoietic progenitors in primates treated with anti-VLA4 integrin. Proc Natl Acad Sci U S A. 1993;90:9374-9378.
25. Papayannopoulou T, Craddock C, Nakamoto B, Priestley GV, Wolf NS. The VLA4/VCAM-1 adhesion pathway defines contrasting mechanisms of lodgement of transplanted murine hemopoietic progenitors between bone marrow and spleen. Proc Natl Acad Sci U S A. 1995;92:9647-9651.
26. Pruijt JFM, van Kooyk Y, Figdor CG, Willemze R, Fibbe WE. Murine hematopoietic progenitor cells with colony-forming or radioprotective capacity lack expression of the β2-integrin LFA-1. Blood. 1999;93:107-112.
27. Itoh K, Tezuka H, Sakoda H, et al. Reproducible establishment of hemopoietic supportive stromal cell lines from murine bone marrow. Exp Hematol. 1989;17:145-153.
28. Reddy GP, Tiarks CY, Pang L, Wuu J, Hsieh CC, Quesenberry PJ. Cell cycle analysis and synchronization of pluripotent hematopoietic progenitor stem cells. Blood. 1997;90:2293-2299.
29. Petzer AL, Zandstra PW, Piret JM, Eaves CJ. Differential cytokine effects on primitive CD34+CD38- human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin. J Exp Med. 1996;183:2551-2558.
30. Jo DY, Rafii S, Hamada T, Moore MA. Chemotaxis of primitive hematopoietic cells in response to stromal cell-derived factor-1. J Clin Invest. 2000;105:101-111.
31. Giet O, Huygen S, Beguin Y, Gothot A. Cell cycle activation of hematopoietic progenitor cells increases very late antigen-5-mediated adhesion to fibronectin. Exp Hematol. 2001;29:515-524.
32. Wayner EA, Garcia-Pardo A, Humphries MJ, McDonald JA, Carter WG. Identification and characterization of the T lymphocyte adhesion receptor for an alternative cell attachment domain (CS-1) in plasma fibronectin. J Cell Biol. 1989;109:1321-1330.
33. Pierschbacher MD, Hayman EG, Ruoslahti E. Location of the cell-attachment site in fibronectin with monoclonal antibodies and proteolytic fragments of the molecule. Cell. 1981;26:259-267.
34. De Vos L, Van Gansen P. Cell morphology, cell filaments and cell death during in vitro ageing: aphidicolin and serum deprivation effects on mouse diploid fibroblasts (a correlated scanning electron microscope and immunocytochemical study). Scan Electron Microsc. 1982;(pt 4):1559-1564.
35. Van Gansen P, Siebertz B, Capone B, Malherbe L. Relationships between cytoplasmic microtubular complex, DNA synthesis and cell morphology in mouse embryonic fibroblasts (effects of age, serum deprivation, aphidicolin, cytochalasin B and colchicine). Biol Cell. 1984;52:161-174.
36. Verfaillie CM, McCarthy JB, McGlave PB. Differentiation of primitive human multipotent hematopoietic progenitors into single lineage clonogenic progenitors is accompanied by alterations in their interaction with fibronectin. J Exp Med. 1991;174: 693-703.
37. Quesenberry P, Habibian H, Dooner M, et al. Physical and physiological plasticity of hematopoietic stem cells. Blood Cells Mol Dis. 2001;27: 934-937.
38. Van der Sluijs JP, Baert MR, Ploemacher RE. Differential adherence of murine hematopoietic stem cell subsets to fibronectin. Exp Hematol. 1994;22: 1236-1243.
39. Elices MJ, Osborn L, Takada Y, et al. VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/fibronectin binding site. Cell. 1990;60:577-584.
40. Jetmore A, Plett PA, Tong X, et al. Homing efficiency, cell cycle kinetics, and survival of quiescent and cycling human CD34(+) cells transplanted into conditioned NOD/SCID recipients. Blood. 2002;99:1585-1593.
41. Arroyo AG, Yang JT, Rayburn H, Hynes RO. α4 integrins regulate the proliferation/differentiation balance of multilineage hematopoietic progenitors in vivo. Immunity. 1999;11:555-566.
42. Liu S, Thomas SM, Woodside DG, et al. Binding of paxillin to α4 integrins modifies integrin-dependent biological responses. Nature. 1999;402:676-681.
43. Giancotti FG. Complexity and specificity of integrin signalling. Nat Cell Biol. 2000;2:E13-E14.