메뉴 건너뛰기




Volumn 78, Issue 10, 2010, Pages 4374-4383

CD4+ T cells and antibody are required for optimal major outer membrane protein vaccine-induced immunity to Chlamydia muridarum genital infection

Author keywords

[No Author keywords available]

Indexed keywords

CPG 1826; IMMUNOLOGICAL ADJUVANT; IMMUNOSTIMULATING AGENT; MONTANIDE ISA 720; OUTER MEMBRANE PROTEIN; OVALBUMIN; UNCLASSIFIED DRUG;

EID: 77957736718     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00622-10     Document Type: Article
Times cited : (89)

References (73)
  • 1
    • 67650671886 scopus 로고    scopus 로고
    • The protective role of antibody responses during Mycobacterium tuberculosis infection
    • Abebe, F., and G. Bjune. 2009. The protective role of antibody responses during Mycobacterium tuberculosis infection. Clin. Exp. Immunol. 157:235-243.
    • (2009) Clin. Exp. Immunol. , vol.157 , pp. 235-243
    • Abebe, F.1    Bjune, G.2
  • 3
    • 0019462336 scopus 로고
    • A new animal model for the study of Chlamydia trachomatis genital infections: Infection of mice with the agent of mouse pneumonitis
    • Barron, A. L., H. J. White, R. G. Rank, B. L. Soloff, and E. B. Moses. 1981. A new animal model for the study of Chlamydia trachomatis genital infections: infection of mice with the agent of mouse pneumonitis. J. Infect. Dis. 143:63-66.
    • (1981) J. Infect. Dis. , vol.143 , pp. 63-66
    • Barron, A.L.1    White, H.J.2    Rank, R.G.3    Soloff, B.L.4    Moses, E.B.5
  • 4
    • 75449119622 scopus 로고
    • The immunology of the trachoma agent with a preliminary report on field trials on vaccine
    • Bell, S. D., Jr., R. L. Nichols, and N. A. Haddad. 1963. The immunology of the trachoma agent with a preliminary report on field trials on vaccine. Invest. Ophthalmol. 2:471-481.
    • (1963) Invest. Ophthalmol. , vol.2 , pp. 471-481
    • Bell Jr., S.D.1    Nichols, R.L.2    Haddad, N.A.3
  • 5
    • 0842326199 scopus 로고    scopus 로고
    • Transcutaneous immunization with combined cholera toxin and CpG adjuvant protects against Chlamydia muridarum genital tract infection
    • Berry, L. J., D. K. Hickey, K. A. Skelding, S. Bao, A. M. Rendina, P. M. Hansbro, C. M. Gockel, and K. W. Beagley. 2004. Transcutaneous immunization with combined cholera toxin and CpG adjuvant protects against Chlamydia muridarum genital tract infection. Infect. Immun. 72:1019-1028.
    • (2004) Infect. Immun. , vol.72 , pp. 1019-1028
    • Berry, L.J.1    Hickey, D.K.2    Skelding, K.A.3    Bao, S.4    Rendina, A.M.5    Hansbro, P.M.6    Gockel, C.M.7    Beagley, K.W.8
  • 6
    • 12844264196 scopus 로고    scopus 로고
    • Antibody-mediated immunomodulation: A strategy to improve host responses against microbial antigens
    • Brady, L. J. 2005. Antibody-mediated immunomodulation: a strategy to improve host responses against microbial antigens. Infect. Immun. 73:671-678.
    • (2005) Infect. Immun. , vol.73 , pp. 671-678
    • Brady, L.J.1
  • 7
    • 13444301093 scopus 로고    scopus 로고
    • Immunology of Chlamydia infection: Implications for a Chlamydia trachomatis vaccine
    • Brunham, R. C., and J. Rey-Ladino. 2005. Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine. Nat. Rev. Immunol. 5:149-161.
    • (2005) Nat. Rev. Immunol. , vol.5 , pp. 149-161
    • Brunham, R.C.1    Rey-Ladino, J.2
  • 8
    • 0034085540 scopus 로고    scopus 로고
    • The potential for vaccine development against chlamydial infection and disease
    • Brunham, R. C., D. J. Zhang, X. Yang, and G. McClarty. 2000. The potential for vaccine development against chlamydial infection and disease. J. Infect. Dis. 181(Suppl. 3):S538-S543.
    • (2000) J. Infect. Dis. , vol.181 , Issue.SUPPL. 3
    • Brunham, R.C.1    Zhang, D.J.2    Yang, X.3    McClarty, G.4
  • 9
    • 0028967628 scopus 로고
    • Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis
    • Cain, T. K., and R. G. Rank. 1995. Local Th1-like responses are induced by intravaginal infection of mice with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect. Immun. 63:1784-1789.
    • (1995) Infect. Immun. , vol.63 , pp. 1784-1789
    • Cain, T.K.1    Rank, R.G.2
  • 10
    • 0019514724 scopus 로고
    • Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis
    • Caldwell, H. D., J. Kromhout, and J. Schachter. 1981. Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis. Infect. Immun. 31:1161-1176.
    • (1981) Infect. Immun. , vol.31 , pp. 1161-1176
    • Caldwell, H.D.1    Kromhout, J.2    Schachter, J.3
  • 11
    • 0042766764 scopus 로고    scopus 로고
    • Antibody-mediated immunity against intracellular pathogens: Two-dimensional thinking comes full circle
    • Casadevall, A. 2003. Antibody-mediated immunity against intracellular pathogens: two-dimensional thinking comes full circle. Infect. Immun. 71: 4225-4228.
    • (2003) Infect. Immun. , vol.71 , pp. 4225-4228
    • Casadevall, A.1
  • 12
    • 0031916168 scopus 로고    scopus 로고
    • Antibody-mediated protection against intracellular pathogens
    • Casadevall, A. 1998. Antibody-mediated protection against intracellular pathogens. Trends Microbiol. 6:102-107.
    • (1998) Trends Microbiol. , vol.6 , pp. 102-107
    • Casadevall, A.1
  • 13
    • 7044231869 scopus 로고    scopus 로고
    • New concepts in antibody-mediated immunity
    • Casadevall, A., and L. A. Pirofski. 2004. New concepts in antibody-mediated immunity. Infect. Immun. 72:6191-6196.
    • (2004) Infect. Immun. , vol.72 , pp. 6191-6196
    • Casadevall, A.1    Pirofski, L.A.2
  • 14
    • 77949898564 scopus 로고    scopus 로고
    • CDC. Centers for Disease Control and Prevention, Atlanta, GA
    • CDC. 2009. Sexually transmitted disease surveillance, 2008. Centers for Disease Control and Prevention, Atlanta, GA.
    • (2009) Sexually Transmitted Disease Surveillance, 2008
  • 16
    • 34247163593 scopus 로고    scopus 로고
    • Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection
    • Cong, Y., M. Jupelli, M. N. Guentzel, G. Zhong, A. K. Murthy, and B. P. Arulanandam. 2007. Intranasal immunization with chlamydial protease-like activity factor and CpG deoxynucleotides enhances protective immunity against genital Chlamydia muridarum infection. Vaccine 25:3773-3780.
    • (2007) Vaccine , vol.25 , pp. 3773-3780
    • Cong, Y.1    Jupelli, M.2    Guentzel, M.N.3    Zhong, G.4    Murthy, A.K.5    Arulanandam, B.P.6
  • 17
    • 0028845224 scopus 로고
    • Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection
    • Cotter, T. W., Q. Meng, Z.-L. Shen, Y.-X. Zhang, H. Su, and H. D. Caldwell. 1995. Protective efficacy of major outer membrane protein-specific immunoglobulin A (IgA) and IgG monoclonal antibodies in a murine model of Chlamydia trachomatis genital tract infection. Infect. Immun. 63:4704-4714.
    • (1995) Infect. Immun. , vol.63 , pp. 4704-4714
    • Cotter, T.W.1    Meng, Q.2    Shen, Z.-L.3    Zhang, Y.-X.4    Su, H.5    Caldwell, H.D.6
  • 18
    • 0030988438 scopus 로고    scopus 로고
    • Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice
    • Cotter, T. W., K. H. Ramsey, G. S. Miranpuri, C. E. Poulsen, and G. I. Byrne. 1997. Dissemination of Chlamydia trachomatis chronic genital tract infection in gamma interferon gene knockout mice. Infect. Immun. 65:2145-2152.
    • (1997) Infect. Immun. , vol.65 , pp. 2145-2152
    • Cotter, T.W.1    Ramsey, K.H.2    Miranpuri, G.S.3    Poulsen, C.E.4    Byrne, G.I.5
  • 20
    • 60049093592 scopus 로고    scopus 로고
    • A Vibrio cholerae ghost-based subunit vaccine induces cross-protective chlamydial immunity that is enhanced by CTA2B, the nontoxic derivative of cholera toxin
    • Ekong, E. E., D. N. Okenu, J. Mania-Pramanik, Q. He, J. U. Igietseme, G. A. Ananaba, D. Lyn, C. Black, and F. O. Eko. 2009. A Vibrio cholerae ghost-based subunit vaccine induces cross-protective chlamydial immunity that is enhanced by CTA2B, the nontoxic derivative of cholera toxin. FEMS Immunol. Med. Microbiol. 55:280-291.
    • (2009) FEMS Immunol. Med. Microbiol. , vol.55 , pp. 280-291
    • Ekong, E.E.1    Okenu, D.N.2    Mania-Pramanik, J.3    He, Q.4    Igietseme, J.U.5    Ananaba, G.A.6    Lyn, D.7    Black, C.8    Eko, F.O.9
  • 22
    • 48849101099 scopus 로고    scopus 로고
    • Chlamydia trachomatis infection: Host immune responses and potential vaccines
    • Hafner, L., K. Beagley, and P. Timms. 2008. Chlamydia trachomatis infection: host immune responses and potential vaccines. Mucosal Immunol. 1:116-130.
    • (2008) Mucosal Immunol. , vol.1 , pp. 116-130
    • Hafner, L.1    Beagley, K.2    Timms, P.3
  • 23
    • 50949133667 scopus 로고    scopus 로고
    • Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model
    • Hansen, J., K. T. Jensen, F. Follmann, E. M. Agger, M. Theisen, and P. Andersen. 2008. Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model. J. Infect. Dis. 198:758-767.
    • (2008) J. Infect. Dis. , vol.198 , pp. 758-767
    • Hansen, J.1    Jensen, K.T.2    Follmann, F.3    Agger, E.M.4    Theisen, M.5    Andersen, P.6
  • 25
    • 4944224144 scopus 로고    scopus 로고
    • Intranasal immunization with C. muridarum major outer membrane protein (MOMP) and cholera toxin elicits local production of neutralizing IgA in the prostate
    • Hickey, D. K., R. C. Jones, S. Bao, A. E. Blake, K. A. Skelding, L. J. Berry, and K. W. Beagley. 2004. Intranasal immunization with C. muridarum major outer membrane protein (MOMP) and cholera toxin elicits local production of neutralizing IgA in the prostate. Vaccine 22:4306-4315.
    • (2004) Vaccine , vol.22 , pp. 4306-4315
    • Hickey, D.K.1    Jones, R.C.2    Bao, S.3    Blake, A.E.4    Skelding, K.A.5    Berry, L.J.6    Beagley, K.W.7
  • 27
    • 0032830635 scopus 로고    scopus 로고
    • Role of gamma interferon in controlling murine chlamydial genital tract infection
    • Ito, J. I., and J. M. Lyons. 1999. Role of gamma interferon in controlling murine chlamydial genital tract infection. Infect. Immun. 67:5518-5521.
    • (1999) Infect. Immun. , vol.67 , pp. 5518-5521
    • Ito, J.I.1    Lyons, J.M.2
  • 28
    • 0031020913 scopus 로고    scopus 로고
    • Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response
    • Johansson, M., K. Schon, M. Ward, and N. Lycke. 1997. Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response. Infect. Immun. 65:1032-1044.
    • (1997) Infect. Immun. , vol.65 , pp. 1032-1044
    • Johansson, M.1    Schon, K.2    Ward, M.3    Lycke, N.4
  • 29
    • 67649201737 scopus 로고    scopus 로고
    • Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: Implication for a trachoma transmission-blocking vaccine
    • Kari, L., W. M. Whitmire, D. D. Crane, N. Reveneau, J. H. Carlson, M. M. Goheen, E. M. Peterson, S. Pal, L. M. de la Maza, and H. D. Caldwell. 2009. Chlamydia trachomatis native major outer membrane protein induces partial protection in nonhuman primates: implication for a trachoma transmission- blocking vaccine. J. Immunol. 182:8063-8070.
    • (2009) J. Immunol. , vol.182 , pp. 8063-8070
    • Kari, L.1    Whitmire, W.M.2    Crane, D.D.3    Reveneau, N.4    Carlson, J.H.5    Goheen, M.M.6    Peterson, E.M.7    Pal, S.8    De La Maza, L.M.9    Caldwell, H.D.10
  • 30
    • 4944232957 scopus 로고    scopus 로고
    • Immune response to the Chlamydia trachomatis outer membrane protein PorB
    • Kawa, D. E., J. Schachter, and R. S. Stephens. 2004. Immune response to the Chlamydia trachomatis outer membrane protein PorB. Vaccine 22:4282-4286.
    • (2004) Vaccine , vol.22 , pp. 4282-4286
    • Kawa, D.E.1    Schachter, J.2    Stephens, R.S.3
  • 31
    • 52049121249 scopus 로고    scopus 로고
    • Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis
    • Kirimanjeswara, G. S., S. Olmos, C. S. Bakshi, and D. W. Metzger. 2008. Humoral and cell-mediated immunity to the intracellular pathogen Francisella tularensis. Immunol. Rev. 225:244-255.
    • (2008) Immunol. Rev. , vol.225 , pp. 244-255
    • Kirimanjeswara, G.S.1    Olmos, S.2    Bakshi, C.S.3    Metzger, D.W.4
  • 32
    • 0025852445 scopus 로고
    • A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene
    • Kitamura, D., J. Roes, R. Kuhn, and K. Rajewsky. 1991. A B cell-deficient mouse by targeted disruption of the membrane exon of the immunoglobulin μ chain gene. Nature 350:423-426.
    • (1991) Nature , vol.350 , pp. 423-426
    • Kitamura, D.1    Roes, J.2    Kuhn, R.3    Rajewsky, K.4
  • 33
    • 38049088066 scopus 로고    scopus 로고
    • Induction of cross-serovar protection against genital chlamydial infection by a targeted multisubunit vaccination approach
    • Li, W., M. N. Guentzel, J. Seshu, G. Zhong, A. K. Murthy, and B. P. Arulanandam. 2007. Induction of cross-serovar protection against genital chlamydial infection by a targeted multisubunit vaccination approach. Clin. Vaccine Immunol. 14:1537-1544.
    • (2007) Clin. Vaccine Immunol. , vol.14 , pp. 1537-1544
    • Li, W.1    Guentzel, M.N.2    Seshu, J.3    Zhong, G.4    Murthy, A.K.5    Arulanandam, B.P.6
  • 34
    • 0022360537 scopus 로고
    • Neutralization of Chlamydia trachomatis cell culture infection by serovar-specific monoclonal antibodies
    • Lucero, M. E., and C.-C. Kuo. 1985. Neutralization of Chlamydia trachomatis cell culture infection by serovar-specific monoclonal antibodies. Infect. Immun. 50:595-597.
    • (1985) Infect. Immun. , vol.50 , pp. 595-597
    • Lucero, M.E.1    Kuo, C.-C.2
  • 36
    • 0024443148 scopus 로고
    • Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes
    • Morgado, M. G., P. Cam, C. Gris-Liebe, P. A. Cazenave, and E. Jouvin-Marche. 1989. Further evidence that BALB/c and C57BL/6 gamma 2a genes originate from two distinct isotypes. EMBO J. 8:3245-3251.
    • (1989) EMBO J. , vol.8 , pp. 3245-3251
    • Morgado, M.G.1    Cam, P.2    Gris-Liebe, C.3    Cazenave, P.A.4    Jouvin-Marche, E.5
  • 37
    • 0028805751 scopus 로고
    • Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection
    • Morrison, R. P., K. Feilzer, and D. B. Tumas. 1995. Gene knockout mice establish a primary protective role for major histocompatibility complex class II-restricted responses in Chlamydia trachomatis genital tract infection. Infect. Immun. 63:4661-4668.
    • (1995) Infect. Immun. , vol.63 , pp. 4661-4668
    • Morrison, R.P.1    Feilzer, K.2    Tumas, D.B.3
  • 38
    • 28244490589 scopus 로고    scopus 로고
    • A predominant role for antibody in acquired immunity to chlamydial genital tract reinfection
    • Morrison, S. G., and R. P. Morrison. 2005. A predominant role for antibody in acquired immunity to chlamydial genital tract reinfection. J. Immunol. 175:7536-7542.
    • (2005) J. Immunol. , vol.175 , pp. 7536-7542
    • Morrison, S.G.1    Morrison, R.P.2
  • 39
    • 0034114441 scopus 로고    scopus 로고
    • In situ analysis of the evolution of the primary immune response in murine Chlamydia trachomatis genital tract infection
    • Morrison, S. G., and R. P. Morrison. 2000. In situ analysis of the evolution of the primary immune response in murine Chlamydia trachomatis genital tract infection. Infect. Immun. 68:2870-2879.
    • (2000) Infect. Immun. , vol.68 , pp. 2870-2879
    • Morrison, S.G.1    Morrison, R.P.2
  • 41
    • 23944521365 scopus 로고    scopus 로고
    • The protective effect of antibody in immunity to murine chlamydial genital tract reinfection is independent of immunoglobulin A
    • Morrison, S. G., and R. P. Morrison. 2005. The protective effect of antibody in immunity to murine chlamydial genital tract reinfection is independent of immunoglobulin A. Infect. Immun. 73:6183-6186.
    • (2005) Infect. Immun. , vol.73 , pp. 6183-6186
    • Morrison, S.G.1    Morrison, R.P.2
  • 44
    • 60049085127 scopus 로고    scopus 로고
    • A limited role for antibody in protective immunity induced by rCPAF and CpG vaccination against primary genital Chlamydia muridarum challenge
    • Murthy, A. K., B. K. Chaganty, W. Li, M. N. Guentzel, J. P. Chambers, J. Seshu, G. Zhong, and B. P. Arulanandam. 2009. A limited role for antibody in protective immunity induced by rCPAF and CpG vaccination against primary genital Chlamydia muridarum challenge. FEMS Immunol. Med. Microbiol. 55:271-279.
    • (2009) FEMS Immunol. Med. Microbiol. , vol.55 , pp. 271-279
    • Murthy, A.K.1    Chaganty, B.K.2    Li, W.3    Guentzel, M.N.4    Chambers, J.P.5    Seshu, J.6    Zhong, G.7    Arulanandam, B.P.8
  • 45
    • 33846849093 scopus 로고    scopus 로고
    • Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production
    • Murthy, A. K., J. P. Chambers, P. A. Meier, G. Zhong, and B. P. Arulanandam. 2007. Intranasal vaccination with a secreted chlamydial protein enhances resolution of genital Chlamydia muridarum infection, protects against oviduct pathology, and is highly dependent upon endogenous gamma interferon production. Infect. Immun. 75:666-676.
    • (2007) Infect. Immun. , vol.75 , pp. 666-676
    • Murthy, A.K.1    Chambers, J.P.2    Meier, P.A.3    Zhong, G.4    Arulanandam, B.P.5
  • 46
    • 33845482256 scopus 로고    scopus 로고
    • Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele
    • Murthy, A. K., Y. Cong, C. Murphey, M. N. Guentzel, T. G. Forsthuber, G. Zhong, and B. P. Arulanandam. 2006. Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infect. Immun. 74:6722-6729.
    • (2006) Infect. Immun. , vol.74 , pp. 6722-6729
    • Murthy, A.K.1    Cong, Y.2    Murphey, C.3    Guentzel, M.N.4    Forsthuber, T.G.5    Zhong, G.6    Arulanandam, B.P.7
  • 47
    • 0036719064 scopus 로고    scopus 로고
    • Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein by use of CpG oligodeoxynucleotides as an adjuvant induces a protective immune response against an intranasal chlamydial challenge
    • Pal, S., H. L. Davis, E. M. Peterson, and L. M. de la Maza. 2002. Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein by use of CpG oligodeoxynucleotides as an adjuvant induces a protective immune response against an intranasal chlamydial challenge. Infect. Immun. 70:4812-4817.
    • (2002) Infect. Immun. , vol.70 , pp. 4812-4817
    • Pal, S.1    Davis, H.L.2    Peterson, E.M.3    De La Maza, L.M.4
  • 48
    • 0028085578 scopus 로고
    • Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumonitis biovar of Chlamydia trachomatis
    • Pal, S., T. J. Fielder, E. M. Peterson, and L. M. de la Maza. 1994. Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect. Immun. 62:3354-3362.
    • (1994) Infect. Immun. , vol.62 , pp. 3354-3362
    • Pal, S.1    Fielder, T.J.2    Peterson, E.M.3    De La Maza, L.M.4
  • 49
    • 0029825440 scopus 로고    scopus 로고
    • Intranasal immunization induces long-term protection in mice against a Chlamydia trachomatis genital challenge
    • Pal, S., E. M. Peterson, and L. M. de la Maza. 1996. Intranasal immunization induces long-term protection in mice against a Chlamydia trachomatis genital challenge. Infect. Immun. 64:5341-5348.
    • (1996) Infect. Immun. , vol.64 , pp. 5341-5348
    • Pal, S.1    Peterson, E.M.2    De La Maza, L.M.3
  • 50
    • 27644446376 scopus 로고    scopus 로고
    • Vaccination of newborn mice induces a strong protective immune response against respiratory and genital challenges with Chlamydia trachomatis
    • Pal, S., E. M. Peterson, and L. M. de la Maza. 2005. Vaccination of newborn mice induces a strong protective immune response against respiratory and genital challenges with Chlamydia trachomatis. Vaccine 23:5351-5358.
    • (2005) Vaccine , vol.23 , pp. 5351-5358
    • Pal, S.1    Peterson, E.M.2    De La Maza, L.M.3
  • 51
    • 28444470161 scopus 로고    scopus 로고
    • Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria
    • Pal, S., E. M. Peterson, and L. M. de la Maza. 2005. Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria. Infect. Immun. 73:8153-8160.
    • (2005) Infect. Immun. , vol.73 , pp. 8153-8160
    • Pal, S.1    Peterson, E.M.2    De La Maza, L.M.3
  • 52
    • 31944451561 scopus 로고    scopus 로고
    • Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse model against a genital challenge
    • Pal, S., E. M. Peterson, R. Rappuoli, G. Ratti, and L. M. de la Maza. 2006. Immunization with the Chlamydia trachomatis major outer membrane protein, using adjuvants developed for human vaccines, can induce partial protection in a mouse model against a genital challenge. Vaccine 24:766-775.
    • (2006) Vaccine , vol.24 , pp. 766-775
    • Pal, S.1    Peterson, E.M.2    Rappuoli, R.3    Ratti, G.4    De La Maza, L.M.5
  • 53
    • 0034819712 scopus 로고    scopus 로고
    • Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein can elicit a protective immune response against a genital challenge
    • Pal, S., I. Theodor, E. Peterson, and L. M. de la Maza. 2001. Immunization with the Chlamydia trachomatis mouse pneumonitis major outer membrane protein can elicit a protective immune response against a genital challenge. Infect. Immun. 69:6240-6247.
    • (2001) Infect. Immun. , vol.69 , pp. 6240-6247
    • Pal, S.1    Theodor, I.2    Peterson, E.3    De La Maza, L.M.4
  • 54
    • 0030934972 scopus 로고    scopus 로고
    • Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge
    • Pal, S., I. Theodor, E. M. Peterson, and L. de la Maza. 1997. Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge. Vaccine 15:575-582.
    • (1997) Vaccine , vol.15 , pp. 575-582
    • Pal, S.1    Theodor, I.2    Peterson, E.M.3    De La Maza, L.4
  • 55
    • 0021720028 scopus 로고
    • In vitro neutralization of Chlamydia trachomatis with monoclonal antibody to an epitope on the major outer membrane protein
    • Peeling, R., I. W. Maclean, and R. C. Brunham. 1984. In vitro neutralization of Chlamydia trachomatis with monoclonal antibody to an epitope on the major outer membrane protein. Infect. Immun. 46:484-488.
    • (1984) Infect. Immun. , vol.46 , pp. 484-488
    • Peeling, R.1    Maclean, I.W.2    Brunham, R.C.3
  • 56
    • 0031112653 scopus 로고    scopus 로고
    • Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-γ-dependent and -independent pathways
    • Perry, L. L., K. Feilzer, and H. D. Caldwell. 1997. Immunity to Chlamydia trachomatis is mediated by T helper 1 cells through IFN-γ-dependent and -independent pathways. J. Immunol. 158:3344-3352.
    • (1997) J. Immunol. , vol.158 , pp. 3344-3352
    • Perry, L.L.1    Feilzer, K.2    Caldwell, H.D.3
  • 57
    • 0030915235 scopus 로고    scopus 로고
    • Effect of immunoglobulin G isotype on the infectivity of Chlamydia trachomatis in a mouse model of intravaginal infection
    • Peterson, E. M., X. Cheng, V. L. Motin, and L. M. de la Maza. 1997. Effect of immunoglobulin G isotype on the infectivity of Chlamydia trachomatis in a mouse model of intravaginal infection. Infect. Immun. 65:2693-2699.
    • (1997) Infect. Immun. , vol.65 , pp. 2693-2699
    • Peterson, E.M.1    Cheng, X.2    Motin, V.L.3    De La Maza, L.M.4
  • 58
    • 0026011410 scopus 로고
    • Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines
    • Ramsey, K. H., and R. G. Rank. 1991. Resolution of chlamydial genital infection with antigen-specific T-lymphocyte lines. Infect. Immun. 59:925-931.
    • (1991) Infect. Immun. , vol.59 , pp. 925-931
    • Ramsey, K.H.1    Rank, R.G.2
  • 59
    • 0021929290 scopus 로고
    • Chronic chlamydial genital infection in congenitally athymic nude mice
    • Rank, R. G., L. S. Soderberg, and A. L. Barron. 1985. Chronic chlamydial genital infection in congenitally athymic nude mice. Infect. Immun. 48:847-849.
    • (1985) Infect. Immun. , vol.48 , pp. 847-849
    • Rank, R.G.1    Soderberg, L.S.2    Barron, A.L.3
  • 60
    • 0031020373 scopus 로고    scopus 로고
    • Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis
    • Rasmussen, S. J., L. Eckmann, A. J. Quayle, L. Shen, Y.-X. Zhang, D. J. Anderson, J. Fierer, R. S. Stephens, and M. F. Kagnoff. 1997. Secretion of proinflammatory cytokines by epithelial cells in response to Chlamydia infection suggests a central role for epithelial cells in chlamydial pathogenesis. J. Clin. Invest. 99:77-87.
    • (1997) J. Clin. Invest. , vol.99 , pp. 77-87
    • Rasmussen, S.J.1    Eckmann, L.2    Quayle, A.J.3    Shen, L.4    Zhang, Y.-X.5    Anderson, D.J.6    Fierer, J.7    Stephens, R.S.8    Kagnoff, M.F.9
  • 61
    • 36949034351 scopus 로고    scopus 로고
    • Immune-mediated control of Chlamydia infection
    • Roan, N. R., and M. N. Starnbach. 2008. Immune-mediated control of Chlamydia infection. Cell. Microbiol. 10:9-19.
    • (2008) Cell. Microbiol. , vol.10 , pp. 9-19
    • Roan, N.R.1    Starnbach, M.N.2
  • 62
    • 70349906776 scopus 로고    scopus 로고
    • Chlamydia vaccine candidates and tools for chlamydial antigen discovery
    • Rockey, D. D., J. Wang, L. Lei, and G. Zhong. 2009. Chlamydia vaccine candidates and tools for chlamydial antigen discovery. Expert Rev. Vaccines 8:1365-1377.
    • (2009) Expert Rev. Vaccines , vol.8 , pp. 1365-1377
    • Rockey, D.D.1    Wang, J.2    Lei, L.3    Zhong, G.4
  • 64
    • 0029162732 scopus 로고
    • + T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract
    • + T cells play a significant role in adoptive immunity to Chlamydia trachomatis infection of the mouse genital tract. Infect. Immun. 63:3302-3308.
    • (1995) Infect. Immun. , vol.63 , pp. 3302-3308
    • Su, H.1    Caldwell, H.D.2
  • 65
    • 0032494186 scopus 로고    scopus 로고
    • Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable chlamydiae
    • Su, H., R. Messer, W. Whitmire, E. Fischer, J. C. Portis, and H. D. Caldwell. 1998. Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable chlamydiae. J. Exp. Med. 188:809-818.
    • (1998) J. Exp. Med. , vol.188 , pp. 809-818
    • Su, H.1    Messer, R.2    Whitmire, W.3    Fischer, E.4    Portis, J.C.5    Caldwell, H.D.6
  • 66
    • 67650621556 scopus 로고    scopus 로고
    • Protection against an intranasal challenge by vaccines formulated with native and recombinant preparations of the Chlamydia trachomatis major outer membrane protein
    • Sun, G., S. Pal, J. Weiland, E. M. Peterson, and L. M. de la Maza. 2009. Protection against an intranasal challenge by vaccines formulated with native and recombinant preparations of the Chlamydia trachomatis major outer membrane protein. Vaccine 27:5020-5025.
    • (2009) Vaccine , vol.27 , pp. 5020-5025
    • Sun, G.1    Pal, S.2    Weiland, J.3    Peterson, E.M.4    De La Maza, L.M.5
  • 70
    • 63149158728 scopus 로고    scopus 로고
    • Novel Chlamydia muridarum T cell antigens induce protective immunity against lung and genital tract infection in murine models
    • Yu, H., X. Jiang, C. Shen, K. P. Karunakaran, and R. C. Brunham. 2009. Novel Chlamydia muridarum T cell antigens induce protective immunity against lung and genital tract infection in murine models. J. Immunol. 182: 1602-1608.
    • (2009) J. Immunol. , vol.182 , pp. 1602-1608
    • Yu, H.1    Jiang, X.2    Shen, C.3    Karunakaran, K.P.4    Brunham, R.C.5
  • 72
    • 0024492598 scopus 로고
    • Protective monoclonal antibodies to Chlamydia trachomatis serovar- and serogroup-specific major outer membrane protein determinants
    • Zhang, Y.-X., S. J. Stewart, and H. D. Caldwell. 1989. Protective monoclonal antibodies to Chlamydia trachomatis serovar- and serogroup-specific major outer membrane protein determinants. Infect. Immun. 57:636-638.
    • (1989) Infect. Immun. , vol.57 , pp. 636-638
    • Zhang, Y.-X.1    Stewart, S.J.2    Caldwell, H.D.3
  • 73
    • 0023128190 scopus 로고
    • Protective monoclonal antibodies recognize epitopes located on the major outer membrane protein of Chlamydia trachomatis
    • Zhang, Y. X., S. Stewart, T. Joseph, H. R. Taylor, and H. D. Caldwell. 1987. Protective monoclonal antibodies recognize epitopes located on the major outer membrane protein of Chlamydia trachomatis. J. Immunol. 138:575-581.
    • (1987) J. Immunol. , vol.138 , pp. 575-581
    • Zhang, Y.X.1    Stewart, S.2    Joseph, T.3    Taylor, H.R.4    Caldwell, H.D.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.