Protection against an intranasal challenge by vaccines formulated with native and recombinant preparations of the Chlamydia trachomatis major outer membrane protein

Vaccine

Volumn 27, Issue 36, 2009, Pages 5020-5025

  Sun, Guifeng ^a   Pal, Sukumar ^a   Weiland, Joseph ^a   Peterson, Ellena M ^a   de la Maza, Luis M ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chlamydia trachomatis; Major outer membrane protein; Mice; Vaccines

Indexed keywords

ADJUVANT; CHLAMYDIA TRACHOMATIS MAJOR OUTER MEMBRANE PROTEIN VACCINE; CHLAMYDIA TRACHOMATIS RECOMBINANT MAJOR OUTER MEMBRANE PROTEIN VACCINE; CPG 1826; GAMMA INTERFERON; INTERLEUKIN 6; MEMBRANE PROTEIN; MONTANIDE ISA 720; NEISSERIA GONORRHOEAE RECOMBINANT PORIN B VACCINE; OUTER MEMBRANE PROTEIN; UNCLASSIFIED DRUG; VACCINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CHLAMYDIA TRACHOMATIS; CONTROLLED STUDY; DRUG CONFORMATION; DRUG FORMULATION; DRUG SYNTHESIS; FEMALE; IMMUNE RESPONSE; INFECTION PREVENTION; MOUSE; NEISSERIA GONORRHOEAE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROVOCATION TEST; VACCINATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, BACTERIAL; BACTERIAL VACCINES; BODY WEIGHT; CELL PROLIFERATION; CHLAMYDIA INFECTIONS; CHLAMYDIA TRACHOMATIS; COLONY COUNT, MICROBIAL; DNA; INJECTIONS, INTRAMUSCULAR; INJECTIONS, SUBCUTANEOUS; LUNG; MANNITOL; MICE; MICE, INBRED BALB C; OLEIC ACIDS; PNEUMONIA; PORINS; T-LYMPHOCYTES; VACCINES, SUBUNIT; VACCINES, SYNTHETIC;

EID: 67650621556     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2009.05.008     Document Type: Article

References (46)

1. Miller W.C., Ford C.A., Morris M., Handcock M.S., Schmitz J.L., Hubbs M.M., et al. Prevalence of chlamydial and gonococcal infections among young adults in the United States. JAMA 291 (2004) 2229-2236
2. Schachter J., and Dawson C. Human chlamydial infections (1978), PSG Publishing Co., Littleton
3. Grayston J.T., and Wang S. New knowledge of chlamydiae and the diseases they cause. J Infect Dis 132 (1975) 87-105
4. Westrom L., Joesoef R., Reynolds G., Hagdu A., and Thompson S.E. Pelvic inflammatory disease and fertility. A cohort study of 1,844 women with laparoscopically verified disease and 657 control women with normal laparoscopic results. Sex Transm Dis 19 (1992) 185-192
5. Dean D., Suchland R.J., and Stamm W.E. Evidence for long-term cervical persistence of Chlamydia trachomatis by omp1 genotyping. J Infect Dis 182 (2000) 909-916
6. Grayston J.T., and Wang S.P. The potential for vaccine against infection of the genital tract with Chlamydia trachomatis. Sex Transm Dis 5 (1978) 73-77
7. Brunham R.C., and Rey-Ladino J. Immunology of Chlamydia infection: implications for a Chlamydia trachomatis vaccine. Nat Rev Immunol 5 (2005) 149-161
8. Baehr W., Zhang Y.X., Joseph T., Su H., Nano F.E., Everett K.D.E., et al. Mapping antigenic domains expressed by Chlamydia trachomatis major outer membrane protein genes. Proc Natl Acad Sci USA 85 (1988) 4000-4004
9. de la Maza M.A., and de la Maza L.M. A new computer model for estimating the impact of vaccination protocols and its application to the study of Chlamydia trachomatis genital infections. Vaccine 13 (1995) 119-127
10. Morrison R.P., and Caldwell H.D. Immunity to murine chlamydial genital infection. Infect Immun 70 (2002) 2741-2751
11. Caldwell H.D., Kromhout J., and Schachter J. Purification and partial characterization of the major outer membrane protein of Chlamydia trachomatis. Infect Immun 31 (1981) 1161-1176
12. Stephens R.S., Sanchez-Pescador R., Wagar E.A., Inouye C., and Urdea M.S. Diversity of Chlamydia trachomatis major outer membrane protein genes. J Bacteriol 169 (1987) 3879-3885
13. Sun G., Pal S., Sarcon A.K., Kim S., Sugawara T., Nikaido H., et al. Structural and functional analyses of the major outer membrane protein of Chlamydia trachomatis. J Bacteriol 189 (2007) 6222-6235
14. Rodriguez-Maranon M.J., Bush R.M., Peterson E.M., Schirmer T., and de la Maza L.M. Prediction of the membrane-spanning beta-strands of the major outer membrane protein of Chlamydia. Protein Sci 11 (2002) 1854-1861
15. Pal S., Peterson E.M., and de la Maza L.M. Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria. Infect Immun 73 (2005) 8153-8160
16. Wang S.P., and Grayston J.T. Classification of trachoma virus strains by protection of mice from toxic death. J Immunol 90 (1963) 849-856
17. Nigg C. An unidentified virus which produces pneumonia and systemic infection in mice. Science 95 (1942) 49-50
18. Marston F.A. The purification of eukaryotic polypeptides synthesized in Escherichia coli. Biochem J 240 (1986) 1-12
19. Qi H.L., Tai J.Y., and Blake M.S. Expression of large amounts of neisserial porin proteins in Escherichia coli and refolding of the proteins into native trimers. Infect Immun 62 (1994) 2432-2439
20. Blake M.S., and Gotschlich E.C. Purification and partial characterization of the opacity-associated proteins of Neisseria gonorrhoeae. J Exp Med 159 (1984) 452-462
21. Schagger H., and von Jagow G. Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa. Anal Biochem 166 (1987) 368-379
22. Weeratna R.D., McCluskie M.J., Xu Y., and Davis H.L. CpG DNA induces stronger immune responses with less toxicity than other adjuvants. Vaccine 18 (2000) 1755-1762
23. Pal S., Fielder T.J., Peterson E.M., and de la Maza L.M. Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumonitis biovar of Chlamydia trachomatis. Infect Immun 62 (1994) 3354-3362
24. Peterson E.M., Zhong G.M., Carlson E., and de la Maza L.M. Protective role of magnesium in the neutralization by antibodies of Chlamydia trachomatis infectivity. Infect Immun 56 (1988) 885-891
25. Taylor H.R., Whittum-Hudson J., Schachter J., Caldwell H.D., and Prendergast R.A. Oral immunization with chlamydial major outer membrane protein (MOMP). Invest Ophthalmol Vis Sci 29 (1988) 1847-1853
26. Dong-Ji Z., Yang X., Shen C., Lu H., Murdin A., and Brunham R.C. Priming with Chlamydia trachomatis major outer membrane protein (MOMP) DNA followed by MOMP ISCOM boosting enhances protection and is associated with increased immunoglobulin A and Th1 cellular immune responses. Infect Immun 68 (2000) 3074-3078
27. Tuffrey M., Alexander F., Conlan W., Woods C., and Ward M. Heterotypic protection of mice against chlamydial salpingitis and colonization of the lower genital tract with a human serovar F isolate of Chlamydia trachomatis by prior immunization with recombinant serovar L1 major outer-membrane protein. J Gen Microbiol 138 (1992) 1707-1715
28. Berry L.J., Hickey D.K., Skelding K.A., Bao S., Rendina A.M., Hansbro P.M., et al. Transcutaneous immunization with combined cholera toxin and CpG adjuvant protects against Chlamydia muridarum genital tract infection. Infect Immun 72 (2004) 1019-1028
29. Batteiger B.E., Rank R.G., Bavoil P.M., and Soderberg L.S. Partial protection against genital reinfection by immunization of guinea-pigs with isolated outer-membrane proteins of the chlamydial agent of guinea-pig inclusion conjunctivitis. J Gen Microbiol 139 (1993) 2965-2972
30. Su H., Messer R., Whitmire W., Fischer E., Portis J.C., and Caldwell H.D. Vaccination against chlamydial genital tract infection after immunization with dendritic cells pulsed ex vivo with nonviable Chlamydiae. J Exp Med 188 (1998) 809-818
31. Tan T.W., Herring A.J., Anderson I.E., and Jones G.E. Protection of sheep against Chlamydia psittaci infection with a subcellular vaccine containing the major outer membrane protein. Infect Immun 58 (1990) 3101-3108
32. Shaw J., Grund V., Durling L., Crane D., and Caldwell H.D. Dendritic cells pulsed with a recombinant chlamydial major outer membrane protein antigen elicit a CD4(+) type 2 rather than type 1 immune response that is not protective. Infect Immun 70 (2002) 1097-1105
33. Hansen J., Jensen K.T., Follmann F., Agger E.M., Theisen M., and Andersen P. Liposome delivery of Chlamydia muridarum major outer membrane protein primes a Th1 response that protects against genital chlamydial infection in a mouse model. J Infect Dis 198 (2008) 758-767
34. Morrison S.G., Su H., Caldwell H.D., and Morrison R.P. Immunity to murine Chlamydia trachomatis genital tract reinfection involves B cells and CD4(+) T cells but not CD8(+) T cells. Infect Immun 68 (2000) 6979-6987
35. Pal S., Bravo J., Peterson E.M., and de la Maza L.M. Protection of wild-type and severe combined immunodeficiency mice against an intranasal challenge by passive immunization with monoclonal antibodies to the Chlamydia trachomatis mouse pneumonitis major outer membrane protein. Infect Immun 76 (2008) 5581-5587
36. Pal S., Theodor I., Peterson E.M., and de la Maza L.M. Monoclonal immunoglobulin A antibody to the major outer membrane protein of the Chlamydia trachomatis mouse pneumonitis biovar protects mice against a chlamydial genital challenge. Vaccine 15 (1997) 575-582
37. Miller J., Williamson E.D., Lakey J.H., Pearce M.J., Jones S.M., and Titball R.W. Macromolecular organisation of recombinant Yersinia pestis F1 antigen and the effect of structure on immunogenicity. FEMS Immunol Med Microbiol 21 (1998) 213-221
38. Ionescu-Matiu I., Kennedy R.C., Sparrow J.T., Culwell A.R., Sanchez Y., Melnick J.L., et al. Epitopes associated with a synthetic hepatitis B surface antigen peptide. J Immunol 130 (1983) 1947-1952
39. Suzich J.A., Ghim S.J., Palmer-Hill F.J., White W.I., Tamura J.K., Bell J.A., et al. Systemic immunization with papillomavirus L1 protein completely prevents the development of viral mucosal papillomas. Proc Natl Acad Sci USA 92 (1995) 11553-11557
40. Musson J.A., Morton M., Walker N., Harper H.M., Mcneill H.V., Williamson E.D., et al. Sequential proteolytic processing of the capsular Caf1 antigen of Yersinia pestis for major histocompatibility complex class II-restricted presentation to T lymphocytes. J Biol Chem 281 (2006) 26129-26135
41. Hanada K., Yewdell J.W., and Yang J.C. Immune recognition of a human renal cancer antigen through post-translational protein splicing. Nature 427 (2004) 252-256
42. Warren E.H., Vigneron N.J., Gavin M.A., Coulie P.G., Stroobant V., Dalet A., et al. An antigen produced by splicing of noncontiguous peptides in the reverse order. Science 313 (2006) 1444-1447
43. Yen T.Y., Pal S., and de la Maza L.M. Characterization of the disulfide bonds and free cysteine residues of the Chlamydia trachomatis mouse pneumonitis major outer membrane protein. Biochemistry 44 (2005) 6250-6256
44. Collins D.S., Unanue E.R., and Harding C.V. Reduction of disulfide bonds within lysosomes is a key step in antigen processing. J Immunol 147 (1991) 4054-4059
45. Jensen P.E. Recent advances in antigen processing and presentation. Nat Immunol 8 (2007) 1041-1048
46. Watts C. The exogenous pathway for antigen presentation on major histocompatibility complex class II and CD1 molecules. Nat Immunol 5 (2004) 685-692