메뉴 건너뛰기




Volumn 30, Issue 10, 2010, Pages 1952-1959

Kruppel-like factor 2 regulates endothelial barrier function

Author keywords

barrier function; endothelium; Kruppel like factor 2

Indexed keywords

ALLYL ISOTHIOCYANATE; EVANS BLUE; FLUORESCEIN ISOTHIOCYANATE DEXTRAN; HYDROGEN PEROXIDE; KRUPPEL LIKE FACTOR 2; MYOSIN LIGHT CHAIN; OCCLUDIN; THROMBIN; KLF2 PROTEIN, HUMAN; KLF2 PROTEIN, MOUSE; KRUPPEL LIKE FACTOR; MEMBRANE PROTEIN; MESSENGER RNA; OCLN PROTEIN, HUMAN; OCLN PROTEIN, MOUSE; RECOMBINANT PROTEIN; SMALL INTERFERING RNA;

EID: 77957695484     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/ATVBAHA.110.211474     Document Type: Article
Times cited : (97)

References (48)
  • 1
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • Mehta D, Malik AB. Signaling mechanisms regulating endothelial permeability. Physiol Rev. 2006;86:279-367.
    • (2006) Physiol Rev , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 3
    • 0032583083 scopus 로고    scopus 로고
    • Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: Role of protein kinases, calcium, and RhoA
    • van Nieuw Amerongen GP, Draijer R, Vermeer MA, van Hinsbergh VW. Transient and prolonged increase in endothelial permeability induced by histamine and thrombin: role of protein kinases, calcium, and RhoA. Circ Res. 1998;83:1115-1123.
    • (1998) Circ Res , vol.83 , pp. 1115-1123
    • Van Nieuw Amerongen, G.P.1    Draijer, R.2    Vermeer, M.A.3    Van Hinsbergh, V.W.4
  • 4
  • 5
    • 0036083071 scopus 로고    scopus 로고
    • Differential effects of histamine and thrombin on endothelial barrier function through actin-myosin tension
    • Moy AB, Blackwell K, Kamath A. Differential effects of histamine and thrombin on endothelial barrier function through actin-myosin tension. Am J Physiol Heart Circ Physiol. 2002;282:H21-H29.
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Moy, A.B.1    Blackwell, K.2    Kamath, A.3
  • 6
    • 34548478100 scopus 로고    scopus 로고
    • Roles of Rho/ROCK and MLCK in TNF-a-induced changes in endothelial morphology and permeability
    • McKenzie JA, Ridley AJ. Roles of Rho/ROCK and MLCK in TNF-a-induced changes in endothelial morphology and permeability. J Cell Physiol. 2007;213:221-228.
    • (2007) J Cell Physiol , vol.213 , pp. 221-228
    • McKenzie, J.A.1    Ridley, A.J.2
  • 7
    • 0028121374 scopus 로고
    • Regulation of vascular endothelial barrier function
    • Lum H, Malik AB. Regulation of vascular endothelial barrier function. Am J Physiol. 1994;267:L223-L241.
    • (1994) Am J Physiol , vol.267
    • Lum, H.1    Malik, A.B.2
  • 8
    • 0042344706 scopus 로고    scopus 로고
    • Rho GTPases and the regulation of endothelial permeability
    • Wojciak-Stothard B, Ridley AJ. Rho GTPases and the regulation of endothelial permeability. Vascul Pharmacol. 2002;39:187-199.
    • (2002) Vascul Pharmacol , vol.39 , pp. 187-199
    • Wojciak-Stothard, B.1    Ridley, A.J.2
  • 9
    • 3042590902 scopus 로고    scopus 로고
    • Endothelial cell-to-cell junctions: Molecular organization and role in vascular homeostasis
    • Bazzoni G, Dejana E. Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol Rev. 2004;84:869-901.
    • (2004) Physiol Rev , vol.84 , pp. 869-901
    • Bazzoni, G.1    Dejana, E.2
  • 10
    • 0025043778 scopus 로고
    • Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction
    • Morel NM, Petruzzo PP, Hechtman HB, Shepro D. Inflammatory agonists that increase microvascular permeability in vivo stimulate cultured pulmonary microvessel endothelial cell contraction. Inflammation. 1990;14: 571-583.
    • (1990) Inflammation , vol.14 , pp. 571-583
    • Morel, N.M.1    Petruzzo, P.P.2    Hechtman, H.B.3    Shepro, D.4
  • 11
    • 0029119895 scopus 로고
    • Myosin light chain kinase-regulated endothelial cell contraction: The relationship between isometric tension, actin polymerization, and myosin phosphorylation
    • Goeckeler ZM, Wysolmerski RB. Myosin light chain kinase-regulated endothelial cell contraction: the relationship between isometric tension, actin polymerization, and myosin phosphorylation. J Cell Biol. 1995;130: 613-627.
    • (1995) J Cell Biol , vol.130 , pp. 613-627
    • Goeckeler, Z.M.1    Wysolmerski, R.B.2
  • 13
    • 0035860820 scopus 로고    scopus 로고
    • Kruppel-like factors: Three fingers in many pies
    • Bieker JJ. Kruppel-like factors: three fingers in many pies. J Biol Chem. 2001;276:34355-34358.
    • (2001) J Biol Chem , vol.276 , pp. 34355-34358
    • Bieker, J.J.1
  • 14
    • 4644265227 scopus 로고    scopus 로고
    • An emerging role for Kruppel-like factors in vascular biology
    • Feinberg MW, Lin Z, Fisch S, Jain MK. An emerging role for Kruppel-like factors in vascular biology. Trends Cardiovasc Med. 2004; 14:241-246.
    • (2004) Trends Cardiovasc Med , vol.14 , pp. 241-246
    • Feinberg, M.W.1    Lin, Z.2    Fisch, S.3    Jain, M.K.4
  • 15
    • 34250868932 scopus 로고    scopus 로고
    • Role of Kruppel-like transcription factors in endothelial biology
    • Atkins GB, Jain MK. Role of Kruppel-like transcription factors in endothelial biology. Circ Res. 2007;100:1686-1695.
    • (2007) Circ Res , vol.100 , pp. 1686-1695
    • Atkins, G.B.1    Jain, M.K.2
  • 20
  • 22
    • 0036122075 scopus 로고    scopus 로고
    • Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor
    • Han ED, MacFarlane RC, Mulligan AN, Scafidi J, Davis AE III. Increased vascular permeability in C1 inhibitor-deficient mice mediated by the bradykinin type 2 receptor. J Clin Invest. 2002;109:1057-1063.
    • (2002) J Clin Invest , vol.109 , pp. 1057-1063
    • Han, E.D.1    MacFarlane, R.C.2    Mulligan, A.N.3    Scafidi, J.4    Davis III, A.E.5
  • 23
    • 0030697515 scopus 로고    scopus 로고
    • The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis
    • Kuo CT, Veselits ML, Barton KP, Lu MM, Clendenin C, Leiden JM. The LKLF transcription factor is required for normal tunica media formation and blood vessel stabilization during murine embryogenesis. Genes Dev. 1997;11:2996-3006.
    • (1997) Genes Dev , vol.11 , pp. 2996-3006
    • Kuo, C.T.1    Veselits, M.L.2    Barton, K.P.3    Lu, M.M.4    Clendenin, C.5    Leiden, J.M.6
  • 24
    • 0030823769 scopus 로고    scopus 로고
    • LKLF: A transcriptional regulator of single-positive T cell quiescence and survival
    • Kuo CT, Veselits ML, Leiden JM. LKLF: a transcriptional regulator of single-positive T cell quiescence and survival. Science. 1997;277: 1986-1990.
    • (1997) Science , vol.277 , pp. 1986-1990
    • Kuo, C.T.1    Veselits, M.L.2    Leiden, J.M.3
  • 26
    • 0035476509 scopus 로고    scopus 로고
    • Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1a
    • Elson DA, Thurston G, Huang LE, Ginzinger DG, McDonald DM, Johnson RS, Arbeit JM. Induction of hypervascularity without leakage or inflammation in transgenic mice overexpressing hypoxia-inducible factor-1a. Genes Dev. 2001;15:2520-2532.
    • (2001) Genes Dev , vol.15 , pp. 2520-2532
    • Elson, D.A.1    Thurston, G.2    Huang, L.E.3    Ginzinger, D.G.4    McDonald, D.M.5    Johnson, R.S.6    Arbeit, J.M.7
  • 27
    • 0034807581 scopus 로고    scopus 로고
    • Cytoskeletal regulation of pulmonary vascular permeability
    • Dudek SM, Garcia JG. Cytoskeletal regulation of pulmonary vascular permeability. J Appl Physiol. 2001;91:1487-1500.
    • (2001) J Appl Physiol , vol.91 , pp. 1487-1500
    • Dudek, S.M.1    Garcia, J.G.2
  • 28
    • 0141456552 scopus 로고    scopus 로고
    • Differential relaxing responses to particulate or soluble guanylyl cyclase activation on endothelial cells: A mechanism dependent on PKG-I a activation by NO/cGMP
    • Rivero-Vilches FJ, de Frutos S, Saura M, Rodriguez-Puyol D, Rodriguez-Puyol M. Differential relaxing responses to particulate or soluble guanylyl cyclase activation on endothelial cells: a mechanism dependent on PKG-I a activation by NO/cGMP. Am J Physiol Cell Physiol. 2003;285:C891-C898.
    • (2003) Am J Physiol Cell Physiol , vol.285
    • Rivero-Vilches, F.J.1    De Frutos, S.2    Saura, M.3    Rodriguez-Puyol, D.4    Rodriguez-Puyol, M.5
  • 29
    • 0030032791 scopus 로고    scopus 로고
    • Cellular consequences of thrombin-receptor activation
    • Grand RJ, Turnell AS, Grabham PW. Cellular consequences of thrombin-receptor activation. Biochem J. 1996;313(pt 2):353-368.
    • (1996) Biochem J , vol.313 , Issue.PART 2 , pp. 353-368
    • Grand, R.J.1    Turnell, A.S.2    Grabham, P.W.3
  • 31
    • 0031595023 scopus 로고    scopus 로고
    • Effects of H1 antagonists on the cutaneous vascular response to histamine and bradykinin: A study using scanning laser Doppler imaging
    • Clough GF, Bennett AR, Church MK. Effects of H1 antagonists on the cutaneous vascular response to histamine and bradykinin: a study using scanning laser Doppler imaging. Br J Dermatol. 1998;138:806-814.
    • (1998) Br J Dermatol , vol.138 , pp. 806-814
    • Clough, G.F.1    Bennett, A.R.2    Church, M.K.3
  • 33
    • 0028980248 scopus 로고
    • Involvement of rho in GTP y S-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: Inhibition of phosphatase activity
    • Noda M, Yasuda-Fukazawa C, Moriishi K, Kato T, Okuda T, Kurokawa K, Takuwa Y. Involvement of rho in GTP y S-induced enhancement of phosphorylation of 20 kDa myosin light chain in vascular smooth muscle cells: inhibition of phosphatase activity. FEBS Lett. 1995;367:246-250.
    • (1995) FEBS Lett , vol.367 , pp. 246-250
    • Noda, M.1    Yasuda-Fukazawa, C.2    Moriishi, K.3    Kato, T.4    Okuda, T.5    Kurokawa, K.6    Takuwa, Y.7
  • 36
    • 33645553318 scopus 로고    scopus 로고
    • Endothelial tight junctions: Permeable barriers of the vessel wall
    • Bazzoni G. Endothelial tight junctions: permeable barriers of the vessel wall. Thromb Haemost. 2006;95:36-42.
    • (2006) Thromb Haemost , vol.95 , pp. 36-42
    • Bazzoni, G.1
  • 37
    • 33747368249 scopus 로고    scopus 로고
    • Blood-brain barrier: Structural components and function under physiologic and pathologic conditions
    • Persidsky Y, Ramirez SH, Haorah J, Kanmogne GD. Blood-brain barrier: structural components and function under physiologic and pathologic conditions. J Neuroimmune Pharmacol. 2006;1:223-236.
    • (2006) J Neuroimmune Pharmacol , vol.1 , pp. 223-236
    • Persidsky, Y.1    Ramirez, S.H.2    Haorah, J.3    Kanmogne, G.D.4
  • 38
    • 64549113715 scopus 로고    scopus 로고
    • TG. F-/3 is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature
    • Walshe TE, Saint-Geniez M, Maharaj AS, Sekiyama E, Maldonado AE, D'Amore PA. TG. F-/3 is required for vascular barrier function, endothelial survival and homeostasis of the adult microvasculature. PLoS One. 2009;4:e5149.
    • (2009) PLoS One , vol.4
    • Walshe, T.E.1    Saint-Geniez, M.2    Maharaj, A.S.3    Sekiyama, E.4    Maldonado, A.E.5    D'Amore, P.A.6
  • 39
    • 67449128444 scopus 로고    scopus 로고
    • Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress
    • McCaffrey G, Willis CL, Staatz WD, Nametz N, Quigley CA, Hom S, Lochhead JJ, Davis TP. Occludin oligomeric assemblies at tight junctions of the blood-brain barrier are altered by hypoxia and reoxygenation stress. J Neurochem. 2009;110:58-71.
    • (2009) J Neurochem , vol.110 , pp. 58-71
    • McCaffrey, G.1    Willis, C.L.2    Staatz, W.D.3    Nametz, N.4    Quigley, C.A.5    Hom, S.6    Lochhead, J.J.7    Davis, T.P.8
  • 40
    • 0035021651 scopus 로고    scopus 로고
    • VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly
    • Wang W, Dentler WL, Borchardt RT. VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly. Am J Physiol Heart Circ Physiol. 2001;280:H434-H440.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280
    • Wang, W.1    Dentler, W.L.2    Borchardt, R.T.3
  • 42
    • 0032813661 scopus 로고    scopus 로고
    • Klf4 is a transcription factor required for establishing the barrier function of the skin
    • Segre JA, Bauer C, Fuchs E. Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat Genet. 1999;22: 356-360.
    • (1999) Nat Genet , vol.22 , pp. 356-360
    • Segre, J.A.1    Bauer, C.2    Fuchs, E.3
  • 43
    • 33845509246 scopus 로고    scopus 로고
    • Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition
    • Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA. Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci USA. 2006;103: 18668-18673.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 18668-18673
    • Patel, S.1    Xi, Z.F.2    Seo, E.Y.3    McGaughey, D.4    Segre, J.A.5
  • 44
    • 0041911182 scopus 로고    scopus 로고
    • Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier
    • Jaubert J, Cheng J, Segre JA. Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003;130:2767-2777.
    • (2003) Development , vol.130 , pp. 2767-2777
    • Jaubert, J.1    Cheng, J.2    Segre, J.A.3
  • 48
    • 74249099068 scopus 로고    scopus 로고
    • Garcia-Cardena G Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype
    • Gracia-Sancho J, Villarreal G Jr, Zhang Y, Garcia-Cardena G Activation of SIRT1 by resveratrol induces KLF2 expression conferring an endothelial vasoprotective phenotype. Cardiovasc Res. 85:514-519.
    • Cardiovasc Res. , vol.85 , pp. 514-519
    • Gracia-Sancho, J.1    Villarreal Jr., G.2    Zhang, Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.