Spinal morphine administration reduces the fatty acid contents in spinal cord and brain by increasing oxidative stress

Neurochemical Research

Volumn 32, Issue 1, 2007, Pages 19-25

  Özmen, Ismail ^a   Naziroǧlu, Mustafa ^b   Alici, H Ahmet ^c   Şahin, Fikrettin ^d   Cengiz, Mustafa ^a   Eren, Ibrahim ^b  

^a SULEYMAN DEMIREL UNIVERSITY   (Turkey)

^b SULEYMAN DEMIREL UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

^c ATATURK UNIVERSITY   (Turkey)

^d YEDITEPE UNIVERSITY   (Turkey)

Author keywords

Acids; Brain; Fatty; Glutathione; Lipid peroxidation; Morphine; Spinal cord

Indexed keywords

ESTER DERIVATIVE; FATTY ACID; GLUTATHIONE; LIPID; MORPHINE; UNSATURATED FATTY ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN CORTEX; BRAIN LEVEL; BRAIN TISSUE; CONTROLLED STUDY; FATTY ACID ANALYSIS; LIPID PEROXIDATION; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; SPINAL CORD;

ANIMALS; BRAIN CHEMISTRY; FATTY ACIDS; GLUTATHIONE; INJECTIONS, SPINAL; LIPID PEROXIDATION; MALE; MORPHINE; OXIDATIVE STRESS; RABBITS; RANDOM ALLOCATION; SPINAL CORD;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 33845912689     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11064-006-9217-5     Document Type: Article

References (27)

1. Atalay M, Sen CK (1999) Physical exercise and antioxidant defenses in the heart. Ann N Y Acad Sci 874:169-177
2. Halliwell B, Gutteridge JMC (1999) Free radicals, other reactive species and disease. In Free Radicals in Biology and Medicine, 3rd ed. Halliwell B, Gutteridge JMC, eds, Oxford University Press, New York, pp 639-645
3. Naziroǧlu M (2006) Effects of physical exercise with a dietary vitamins C and E combination on oxidative stress in muscle, liver and brain of streptozotocin- induced diabetic pregnant rat. Vitamin E: New Research. Ed. MH Braunstain, Nova Science Publishers Inc., NY, USA. pp 69-83
4. Guzman DC, Vazquez IE, Brizuela NO, Alvarez RG, Mejia GB, Garcia EH, Santamaria D, de Apreza MR, Olguin HJ (2006) Assessment of oxidative damage induced by acute doses of morphine sulfate in postnatal and adult rat brain. Neurochem Res 31:549-554
5. Xu B, Wang Z, Li G, Li B, Lin H, Zheng R, Zheng Q. (2006) Heroin-administered mice involved in oxidative stress and exogenous antioxidant-alleviated withdrawal syndrome. Basic Clin Pharmacol Toxicol. 99:153-161
6. Zhang YT, Zheng QS, Pan J, Zheng RL. (2004) Oxidative damage of biomolecules in mouse liver induced by morphine and protected by antioxidants. Basic Clin Pharmacol Toxicol. 95:53-58
7. Naziroǧlu M, Brandsch C. (2006) Dietary hydrogenated soybean oil affects lipid and vitamin E metabolism in rats. J Nutr Sci Vitaminol (Tokyo). 52:83-88, 2006
8. Yilmaz O, Celik S, Cay M, Naziroglu M. (1997) Protective role of intraperitoneally administrated vitamin E and selenium on the levels of total lipid, total cholesterol, and fatty acid composition of muscle and liver tissues in rats. Cell Biochem 64:233-241
9. Celik S, Yilmaz O, Asan T, Naziroglu M, Cay M, Aksakal M. (1999) Influence of dietary selenium and vitamin E on the levels of fatty acids in brain and liver tissues of lambs. Cell Biochem Funct 17:115-121
10. Sherlock Microbial Identification System (version 4.0), MIS Operating manual, 145 pp, MIDI, Inc, Newark, DE, USA
11. Mercandate S. (1999) Problems of long-term spinal opioid treatment in advanced cancer patients. Pain 79:1-13
12. Wagemans MF, van der Valk P, Spoelder EM, Zuurmond WW, de Lange JJ (1997) Neurohistopathological findings after continuous intrathecal administration of morphine or a morphine/bupivacaine mixture in cancer pain patients. Acta Anaesthesiol Scand 41:1033-1038
13. Hodgson PS, Neal JM, Pollock JE, Liu SS (1999) The neurotoxicity of drugs given intrathecally (spinal). Anesth Analg 88:797-809
14. Yaksh TL, Noueihed RY, Durant PA (1986) Studies of the pharmacology and pathology of intrathecally administered 4-anilinopiperidine analogues and morphine in the rat and cat. Anesthesiology 64:54-66, 1986
15. Alici HA, Ozmen I, Cesur M, Sahin F (2003) Effect of the spinal drug tramadol on the fatty acid compositions of rabbit spinal cord and brain. Biol Pharm Bull 26:1403-1406
16. Placer ZA, Cushman L, Johnson BC (1966) Estimation of products of lipid peroxidation (malonyl dialdehyde) in biological fluids. Anal Biochem 16:359-364
17. Sedlak J, Lindsay RHC (1968) Estimation of total, protein bound and non-protein sulfhydryl groups in tissue with Ellmann' s reagent. Anal Biochem 25:192-205
18. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin- Phenol reagent. J Biol Chem 193:265-275
19. Di Chiara G, Imperato A. (1988) Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proc Natl Acad Sci USA. 85:5274-5278
20. Olanow CW, Tatton WG. (1999) Etiology and pathogenesis of Parkinson's disease. Annu Rev Neurosci 22:123-144
21. Singhal PC, Pamarthi M, Shah R, Chandra D, Gibbons N (1994) Morphine stimulates superoxide formation by glomerular mesangial cells. Inflammation. 18:293-299
22. Di Bello MG, Masini E, Ioannides C, Fomusi Ndisang J, Raspanti S, Bani Sacchi T, Mannaioni PF (1998) Histamine release from rat mast cells induced by the metabolic activation of drugs of abuse into free radicals. Inflamm Res. 47:122-130
23. Goudas LC, Langlade A, Serrie A, Matson W, Milbury P, Thurel C, Sandouk P, Carr DB. (1999). Acute decreases in cerebrospinal fluid glutathione levels after intracerebroventricular morphine for cancer pain. Anesth Analg. 89:1209-1215
24. Farooqui AA, Yi Ong W, Lu XR, Halliwell B, Horrocks LA. (2001) Neurochemical consequences of kainate-induced toxicity in brain: involvement of arachidonic acid release and prevention of toxicity by phospholipase A(2) inhibitors. Brain Res Brain Res Rev 38:61-78
25. Kumar R, Agarwal AK, Seth PK (1996) Oxidative stress-mediated neurotoxicity of cadmium. Toxicol Lett 89:65-69
26. Subramaniam R, Roediger F, Jordan B, Mattson MP, Keller JN, Waeg G, Butterfield DA (1997) The lipid peroxidation product, 4-hydroxy-2-trans-nonenal, alters the conformation of cortical synaptosomal membrane proteins. J Neurochem 69:1161-1169
27. Alici HA, Ozmen I, Cesur M, Sahin F. (2003) Effect of the spinal drug tramadol on the fatty acid compositions of rabbit spinal cord and brain. Biol Pharm Bull 26:1403-1406