-
1
-
-
0347989161
-
The causes and consequences of HIV evolution
-
10.1038/nrg1246, 14708016
-
Rambaut A, Posada D, Crandall KA, Holmes EC. The causes and consequences of HIV evolution. Nat Rev Genet 2004, 5:52-61. 10.1038/nrg1246, 14708016.
-
(2004)
Nat Rev Genet
, vol.5
, pp. 52-61
-
-
Rambaut, A.1
Posada, D.2
Crandall, K.A.3
Holmes, E.C.4
-
2
-
-
0034615972
-
HIV-1 nomenclature proposal
-
10.1126/science.288.5463.55d, 10766634
-
Robertson DL, Anderson JP, Bradac JA, Carr JK, Foley B, Funkhouser RK, Gao F, Hahn BH, Kalish ML, Kuiken C, et al. HIV-1 nomenclature proposal. Science 2000, 288:55-56. 10.1126/science.288.5463.55d, 10766634.
-
(2000)
Science
, vol.288
, pp. 55-56
-
-
Robertson, D.L.1
Anderson, J.P.2
Bradac, J.A.3
Carr, J.K.4
Foley, B.5
Funkhouser, R.K.6
Gao, F.7
Hahn, B.H.8
Kalish, M.L.9
Kuiken, C.10
-
3
-
-
0034631503
-
Accelerating the development and future availability of HIV-1 vaccines: why, when, where, and how?
-
10.1016/S0140-6736(00)02360-6, 10885368
-
Esparza J, Bhamarapravati N. Accelerating the development and future availability of HIV-1 vaccines: why, when, where, and how?. Lancet 2000, 355:2061-2066. 10.1016/S0140-6736(00)02360-6, 10885368.
-
(2000)
Lancet
, vol.355
, pp. 2061-2066
-
-
Esparza, J.1
Bhamarapravati, N.2
-
4
-
-
33750253231
-
Global and regional distribution of HIV-1 genetic subtypes and recombinants in 2004
-
10.1097/01.aids.0000247564.73009.bc, 17053344
-
Hemelaar J, Gouws E, Ghys PD, Osmanov S. Global and regional distribution of HIV-1 genetic subtypes and recombinants in 2004. AIDS 2006, 20:W13-23. 10.1097/01.aids.0000247564.73009.bc, 17053344.
-
(2006)
AIDS
, vol.20
-
-
Hemelaar, J.1
Gouws, E.2
Ghys, P.D.3
Osmanov, S.4
-
5
-
-
0024999452
-
Retroviral reverse transcriptase: synthesis, structure, and function
-
Goff SP. Retroviral reverse transcriptase: synthesis, structure, and function. J Acquir Immune Defic Syndr 1990, 3:817-831.
-
(1990)
J Acquir Immune Defic Syndr
, vol.3
, pp. 817-831
-
-
Goff, S.P.1
-
6
-
-
0023268502
-
The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial
-
10.1056/NEJM198707233170401, 3299089
-
Fischl MA, Richman DD, Grieco MH, Gottlieb MS, Volberding PA, Laskin OL, Leedom JM, Groopman JE, Mildvan D, Schooley RT, et al. The efficacy of azidothymidine (AZT) in the treatment of patients with AIDS and AIDS-related complex. A double-blind, placebo-controlled trial. N Engl J Med 1987, 317:185-191. 10.1056/NEJM198707233170401, 3299089.
-
(1987)
N Engl J Med
, vol.317
, pp. 185-191
-
-
Fischl, M.A.1
Richman, D.D.2
Grieco, M.H.3
Gottlieb, M.S.4
Volberding, P.A.5
Laskin, O.L.6
Leedom, J.M.7
Groopman, J.E.8
Mildvan, D.9
Schooley, R.T.10
-
7
-
-
0026693137
-
Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor
-
10.1126/science.1377403, 1377403
-
Kohlstaedt LA, Wang J, Friedman JM, Rice PA, Steitz TA. Crystal structure at 3.5 A resolution of HIV-1 reverse transcriptase complexed with an inhibitor. Science 1992, 256:1783-1790. 10.1126/science.1377403, 1377403.
-
(1992)
Science
, vol.256
, pp. 1783-1790
-
-
Kohlstaedt, L.A.1
Wang, J.2
Friedman, J.M.3
Rice, P.A.4
Steitz, T.A.5
-
8
-
-
43049125772
-
RNase H activity: structure, specificity, and function in reverse transcription
-
10.1016/j.virusres.2007.12.007, 2464458, 18261820
-
Schultz SJ, Champoux JJ. RNase H activity: structure, specificity, and function in reverse transcription. Virus Res 2008, 134:86-103. 10.1016/j.virusres.2007.12.007, 2464458, 18261820.
-
(2008)
Virus Res
, vol.134
, pp. 86-103
-
-
Schultz, S.J.1
Champoux, J.J.2
-
9
-
-
13544276913
-
6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro
-
10.1016/j.antiviral.2004.11.002, 15708638
-
Tramontano E, Esposito F, Badas R, Di Santo R, Costi R, La Colla P. 6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro. Antiviral Res 2005, 65:117-124. 10.1016/j.antiviral.2004.11.002, 15708638.
-
(2005)
Antiviral Res
, vol.65
, pp. 117-124
-
-
Tramontano, E.1
Esposito, F.2
Badas, R.3
Di Santo, R.4
Costi, R.5
La Colla, P.6
-
10
-
-
77949324191
-
Update of the drug resistance mutations in HIV-1: December 2009
-
Johnson VA, Brun-Vezinet F, Clotet B, Gunthard HF, Kuritzkes DR, Pillay D, Schapiro JM, Richman DD. Update of the drug resistance mutations in HIV-1: December 2009. Top HIV Med 2009, 17:138-145.
-
(2009)
Top HIV Med
, vol.17
, pp. 138-145
-
-
Johnson, V.A.1
Brun-Vezinet, F.2
Clotet, B.3
Gunthard, H.F.4
Kuritzkes, D.R.5
Pillay, D.6
Schapiro, J.M.7
Richman, D.D.8
-
11
-
-
58149133507
-
Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition
-
10.1016/j.jmb.2008.10.071, 2881421, 19022262
-
Sarafianos SG, Marchand B, Das K, Himmel DM, Parniak MA, Hughes SH, Arnold E. Structure and function of HIV-1 reverse transcriptase: molecular mechanisms of polymerization and inhibition. J Mol Biol 2009, 385:693-713. 10.1016/j.jmb.2008.10.071, 2881421, 19022262.
-
(2009)
J Mol Biol
, vol.385
, pp. 693-713
-
-
Sarafianos, S.G.1
Marchand, B.2
Das, K.3
Himmel, D.M.4
Parniak, M.A.5
Hughes, S.H.6
Arnold, E.7
-
12
-
-
33745853539
-
HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture
-
10.1097/01.aids.0000232228.88511.0b, 16816549
-
Brenner BG, Oliveira M, Doualla-Bell F, Moisi DD, Ntemgwa M, Frankel F, Essex M, Wainberg MA. HIV-1 subtype C viruses rapidly develop K65R resistance to tenofovir in cell culture. AIDS 2006, 20:F9-13. 10.1097/01.aids.0000232228.88511.0b, 16816549.
-
(2006)
AIDS
, vol.20
-
-
Brenner, B.G.1
Oliveira, M.2
Doualla-Bell, F.3
Moisi, D.D.4
Ntemgwa, M.5
Frankel, F.6
Essex, M.7
Wainberg, M.A.8
-
13
-
-
27544479497
-
K65R and Y181C are less prevalent in HAART-experienced HIV-1 subtype A patients
-
10.1097/01.aids.0000189860.36688.e5, 16227803
-
Gupta RK, Chrystie IL, O'Shea S, Mullen JE, Kulasegaram R, Tong CY. K65R and Y181C are less prevalent in HAART-experienced HIV-1 subtype A patients. AIDS 2005, 19:1916-1919. 10.1097/01.aids.0000189860.36688.e5, 16227803.
-
(2005)
AIDS
, vol.19
, pp. 1916-1919
-
-
Gupta, R.K.1
Chrystie, I.L.2
O'Shea, S.3
Mullen, J.E.4
Kulasegaram, R.5
Tong, C.Y.6
-
14
-
-
70349428513
-
Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C
-
10.1086/605894, 19764886
-
Invernizzi CF, Coutsinos D, Oliveira M, Moisi D, Brenner BG, Wainberg MA. Signature nucleotide polymorphisms at positions 64 and 65 in reverse transcriptase favor the selection of the K65R resistance mutation in HIV-1 subtype C. J Infect Dis 2009, 200:1202-1206. 10.1086/605894, 19764886.
-
(2009)
J Infect Dis
, vol.200
, pp. 1202-1206
-
-
Invernizzi, C.F.1
Coutsinos, D.2
Oliveira, M.3
Moisi, D.4
Brenner, B.G.5
Wainberg, M.A.6
-
15
-
-
59549100674
-
Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: a systematic review of virologic and biochemical evidence
-
Martinez-Cajas JL, Pant-Pai N, Klein MB, Wainberg MA. Role of genetic diversity amongst HIV-1 non-B subtypes in drug resistance: a systematic review of virologic and biochemical evidence. AIDS Rev 2008, 10:212-223.
-
(2008)
AIDS Rev
, vol.10
, pp. 212-223
-
-
Martinez-Cajas, J.L.1
Pant-Pai, N.2
Klein, M.B.3
Wainberg, M.A.4
-
16
-
-
0035887670
-
Human immunodeficiency virus type 1 reverse-transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a northern California clinic-based population
-
10.1086/323601, 2597357, 11574914
-
Gonzales MJ, Machekano RN, Shafer RW. Human immunodeficiency virus type 1 reverse-transcriptase and protease subtypes: classification, amino acid mutation patterns, and prevalence in a northern California clinic-based population. J Infect Dis 2001, 184:998-1006. 10.1086/323601, 2597357, 11574914.
-
(2001)
J Infect Dis
, vol.184
, pp. 998-1006
-
-
Gonzales, M.J.1
Machekano, R.N.2
Shafer, R.W.3
-
17
-
-
0025191211
-
Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography
-
10.1111/j.1432-1033.1990.tb15306.x, 1688798
-
Le Grice SF, Gruninger-Leitch F. Rapid purification of homodimer and heterodimer HIV-1 reverse transcriptase by metal chelate affinity chromatography. Eur J Biochem 1990, 187:307-314. 10.1111/j.1432-1033.1990.tb15306.x, 1688798.
-
(1990)
Eur J Biochem
, vol.187
, pp. 307-314
-
-
Le Grice, S.F.1
Gruninger-Leitch, F.2
-
18
-
-
0029813382
-
Expression and purification of retroviral HIV-1 reverse transcriptase
-
full_text, 9026635
-
Stahlhut MW, Olsen DB. Expression and purification of retroviral HIV-1 reverse transcriptase. Methods Enzymol 1996, 275:122-133. full_text, 9026635.
-
(1996)
Methods Enzymol
, vol.275
, pp. 122-133
-
-
Stahlhut, M.W.1
Olsen, D.B.2
-
19
-
-
0033118205
-
Mixed reconstitution of mutated subunits of HIV-1 reverse transcriptase coexpressed in Escherichia coli - two tags tie it up
-
10.1046/j.1432-1327.1999.00304.x, 10103027
-
Maier G, Dietrich U, Panhans B, Schroder B, Rubsamen-Waigmann H, Cellai L, Hermann T, Heumann H. Mixed reconstitution of mutated subunits of HIV-1 reverse transcriptase coexpressed in Escherichia coli - two tags tie it up. Eur J Biochem 1999, 261:10-18. 10.1046/j.1432-1327.1999.00304.x, 10103027.
-
(1999)
Eur J Biochem
, vol.261
, pp. 10-18
-
-
Maier, G.1
Dietrich, U.2
Panhans, B.3
Schroder, B.4
Rubsamen-Waigmann, H.5
Cellai, L.6
Hermann, T.7
Heumann, H.8
-
20
-
-
0030060362
-
Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis
-
10.1021/bi9516642, 8652558
-
Pandey VN, Kaushik N, Rege N, Sarafianos SG, Yadav PN, Modak MJ. Role of methionine 184 of human immunodeficiency virus type-1 reverse transcriptase in the polymerase function and fidelity of DNA synthesis. Biochemistry 1996, 35:2168-2179. 10.1021/bi9516642, 8652558.
-
(1996)
Biochemistry
, vol.35
, pp. 2168-2179
-
-
Pandey, V.N.1
Kaushik, N.2
Rege, N.3
Sarafianos, S.G.4
Yadav, P.N.5
Modak, M.J.6
-
21
-
-
0028675040
-
Purification and characterization of HIV-1 reverse transcriptase having a 1:1 ratio of p66 and p51 subunits
-
10.1006/prep.1994.1084, 7532052
-
Stahlhut M, Li Y, Condra JH, Fu J, Gotlib L, Graham DJ, Olsen DB. Purification and characterization of HIV-1 reverse transcriptase having a 1:1 ratio of p66 and p51 subunits. Protein Expr Purif 1994, 5:614-621. 10.1006/prep.1994.1084, 7532052.
-
(1994)
Protein Expr Purif
, vol.5
, pp. 614-621
-
-
Stahlhut, M.1
Li, Y.2
Condra, J.H.3
Fu, J.4
Gotlib, L.5
Graham, D.J.6
Olsen, D.B.7
-
22
-
-
34248380089
-
Cross-clade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers
-
10.1128/JVI.01923-06, 1900219, 17329328
-
Held DM, Kissel JD, Thacker SJ, Michalowski D, Saran D, Ji J, Hardy RW, Rossi JJ, Burke DH. Cross-clade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers. J Virol 2007, 81:5375-5384. 10.1128/JVI.01923-06, 1900219, 17329328.
-
(2007)
J Virol
, vol.81
, pp. 5375-5384
-
-
Held, D.M.1
Kissel, J.D.2
Thacker, S.J.3
Michalowski, D.4
Saran, D.5
Ji, J.6
Hardy, R.W.7
Rossi, J.J.8
Burke, D.H.9
-
23
-
-
0028789990
-
Purification and characterization of human immunodeficiency virus type 1 reverse transcriptase
-
full_text, 8594344
-
Le Grice SF, Cameron CE, Benkovic SJ. Purification and characterization of human immunodeficiency virus type 1 reverse transcriptase. Methods Enzymol 1995, 262:130-144. full_text, 8594344.
-
(1995)
Methods Enzymol
, vol.262
, pp. 130-144
-
-
Le Grice, S.F.1
Cameron, C.E.2
Benkovic, S.J.3
-
24
-
-
0032574695
-
Fidelity of mutant HIV-1 reverse transcriptases: interaction with the single-stranded template influences the accuracy of DNA synthesis
-
10.1021/bi972672g, 9558316
-
Kim B, Hathaway TR, Loeb LA. Fidelity of mutant HIV-1 reverse transcriptases: interaction with the single-stranded template influences the accuracy of DNA synthesis. Biochemistry 1998, 37:5831-5839. 10.1021/bi972672g, 9558316.
-
(1998)
Biochemistry
, vol.37
, pp. 5831-5839
-
-
Kim, B.1
Hathaway, T.R.2
Loeb, L.A.3
-
25
-
-
0033600921
-
New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity
-
10.1074/jbc.274.39.27666, 10488107
-
Kim B, Ayran JC, Sagar SG, Adman ET, Fuller SM, Tran NH, Horrigan J. New human immunodeficiency virus, type 1 reverse transcriptase (HIV-1 RT) mutants with increased fidelity of DNA synthesis. Accuracy, template binding, and processivity. J Biol Chem 1999, 274:27666-27673. 10.1074/jbc.274.39.27666, 10488107.
-
(1999)
J Biol Chem
, vol.274
, pp. 27666-27673
-
-
Kim, B.1
Ayran, J.C.2
Sagar, S.G.3
Adman, E.T.4
Fuller, S.M.5
Tran, N.H.6
Horrigan, J.7
-
26
-
-
33646146697
-
Susceptibility to antiretroviral drugs of CRF01_AE, CRF02_AG, and subtype C viruses from untreated patients of Africa and Asia: comparative genotypic and phenotypic data
-
10.1089/aid.2006.22.357, 16623640
-
Fleury HJ, Toni T, Lan NT, Hung PV, Deshpande A, Recordon-Pinson P, Boucher S, Lazaro E, Jauvin V, Lavignolle-Aurillac V, et al. Susceptibility to antiretroviral drugs of CRF01_AE, CRF02_AG, and subtype C viruses from untreated patients of Africa and Asia: comparative genotypic and phenotypic data. AIDS Res Hum Retroviruses 2006, 22:357-366. 10.1089/aid.2006.22.357, 16623640.
-
(2006)
AIDS Res Hum Retroviruses
, vol.22
, pp. 357-366
-
-
Fleury, H.J.1
Toni, T.2
Lan, N.T.3
Hung, P.V.4
Deshpande, A.5
Recordon-Pinson, P.6
Boucher, S.7
Lazaro, E.8
Jauvin, V.9
Lavignolle-Aurillac, V.10
-
27
-
-
0042201895
-
Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity
-
10.1128/JVI.77.16.8621-8632.2003, 167213, 12885880
-
Diallo K, Marchand B, Wei X, Cellai L, Gotte M, Wainberg MA. Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity. J Virol 2003, 77:8621-8632. 10.1128/JVI.77.16.8621-8632.2003, 167213, 12885880.
-
(2003)
J Virol
, vol.77
, pp. 8621-8632
-
-
Diallo, K.1
Marchand, B.2
Wei, X.3
Cellai, L.4
Gotte, M.5
Wainberg, M.A.6
-
28
-
-
0037032908
-
The M184V mutation in HIV-1 reverse transcriptase reduces the restoration of wild-type replication by attenuated viruses
-
10.1097/00002030-200212060-00003, 12461412
-
Wei X, Liang C, Gotte M, Wainberg MA. The M184V mutation in HIV-1 reverse transcriptase reduces the restoration of wild-type replication by attenuated viruses. AIDS 2002, 16:2391-2398. 10.1097/00002030-200212060-00003, 12461412.
-
(2002)
AIDS
, vol.16
, pp. 2391-2398
-
-
Wei, X.1
Liang, C.2
Gotte, M.3
Wainberg, M.A.4
-
29
-
-
0029757751
-
Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme
-
452124, 8670908
-
Back NK, Nijhuis M, Keulen W, Boucher CA, Oude Essink BO, van Kuilenburg AB, van Gennip AH, Berkhout B. Reduced replication of 3TC-resistant HIV-1 variants in primary cells due to a processivity defect of the reverse transcriptase enzyme. EMBO J 1996, 15:4040-4049. 452124, 8670908.
-
(1996)
EMBO J
, vol.15
, pp. 4040-4049
-
-
Back, N.K.1
Nijhuis, M.2
Keulen, W.3
Boucher, C.A.4
Oude Essink, B.O.5
van Kuilenburg, A.B.6
van Gennip, A.H.7
Berkhout, B.8
-
30
-
-
0030004944
-
Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication
-
190052, 8642636
-
Caliendo AM, Savara A, An D, DeVore K, Kaplan JC, D'Aquila RT. Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication. J Virol 1996, 70:2146-2153. 190052, 8642636.
-
(1996)
J Virol
, vol.70
, pp. 2146-2153
-
-
Caliendo, A.M.1
Savara, A.2
An, D.3
DeVore, K.4
Kaplan, J.C.5
D'Aquila, R.T.6
-
31
-
-
0037223706
-
Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C
-
10.1128/JVI.77.2.1021-1038.2003, 140829, 12502818
-
Ball SC, Abraha A, Collins KR, Marozsan AJ, Baird H, Quinones-Mateu ME, Penn-Nicholson A, Murray M, Richard N, Lobritz M, et al. Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C. J Virol 2003, 77:1021-1038. 10.1128/JVI.77.2.1021-1038.2003, 140829, 12502818.
-
(2003)
J Virol
, vol.77
, pp. 1021-1038
-
-
Ball, S.C.1
Abraha, A.2
Collins, K.R.3
Marozsan, A.J.4
Baird, H.5
Quinones-Mateu, M.E.6
Penn-Nicholson, A.7
Murray, M.8
Richard, N.9
Lobritz, M.10
-
32
-
-
18844372793
-
Differences in the fitness of two diverse wild-type human immunodeficiency virus type 1 isolates are related to the efficiency of cell binding and entry
-
10.1128/JVI.79.11.7121-7134.2005, 1112120, 15890952
-
Marozsan AJ, Moore DM, Lobritz MA, Fraundorf E, Abraha A, Reeves JD, Arts EJ. Differences in the fitness of two diverse wild-type human immunodeficiency virus type 1 isolates are related to the efficiency of cell binding and entry. J Virol 2005, 79:7121-7134. 10.1128/JVI.79.11.7121-7134.2005, 1112120, 15890952.
-
(2005)
J Virol
, vol.79
, pp. 7121-7134
-
-
Marozsan, A.J.1
Moore, D.M.2
Lobritz, M.A.3
Fraundorf, E.4
Abraha, A.5
Reeves, J.D.6
Arts, E.J.7
-
33
-
-
0242354002
-
Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase
-
10.1128/AAC.47.11.3377-3383.2003, 253767, 14576091
-
Diallo K, Gotte M, Wainberg MA. Molecular impact of the M184V mutation in human immunodeficiency virus type 1 reverse transcriptase. Antimicrob Agents Chemother 2003, 47:3377-3383. 10.1128/AAC.47.11.3377-3383.2003, 253767, 14576091.
-
(2003)
Antimicrob Agents Chemother
, vol.47
, pp. 3377-3383
-
-
Diallo, K.1
Gotte, M.2
Wainberg, M.A.3
-
34
-
-
58149160464
-
Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity
-
10.1021/cb8001039, 2941776, 18831589
-
Wendeler M, Lee HF, Bermingham A, Miller JT, Chertov O, Bona MK, Baichoo NS, Ehteshami M, Beutler J, O'Keefe BR, et al. Vinylogous ureas as a novel class of inhibitors of reverse transcriptase-associated ribonuclease H activity. ACS Chem Biol 2008, 3:635-644. 10.1021/cb8001039, 2941776, 18831589.
-
(2008)
ACS Chem Biol
, vol.3
, pp. 635-644
-
-
Wendeler, M.1
Lee, H.F.2
Bermingham, A.3
Miller, J.T.4
Chertov, O.5
Bona, M.K.6
Baichoo, N.S.7
Ehteshami, M.8
Beutler, J.9
O'Keefe, B.R.10
-
35
-
-
59649106106
-
Effects of mutations in the connection and RNase H domains of HIV-1 reverse transcriptase on drug susceptibility
-
Ehteshami M, Gotte M. Effects of mutations in the connection and RNase H domains of HIV-1 reverse transcriptase on drug susceptibility. AIDS Rev 2008, 10:224-235.
-
(2008)
AIDS Rev
, vol.10
, pp. 224-235
-
-
Ehteshami, M.1
Gotte, M.2
-
36
-
-
59649120492
-
Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1
-
10.1128/JVI.01349-08, 2643749, 19073730
-
Coutsinos D, Invernizzi CF, Xu H, Moisi D, Oliveira M, Brenner BG, Wainberg MA. Template usage is responsible for the preferential acquisition of the K65R reverse transcriptase mutation in subtype C variants of human immunodeficiency virus type 1. J Virol 2009, 83:2029-2033. 10.1128/JVI.01349-08, 2643749, 19073730.
-
(2009)
J Virol
, vol.83
, pp. 2029-2033
-
-
Coutsinos, D.1
Invernizzi, C.F.2
Xu, H.3
Moisi, D.4
Oliveira, M.5
Brenner, B.G.6
Wainberg, M.A.7
-
37
-
-
57349200456
-
Silent mutations are selected in HIV-1 reverse transcriptase and affect enzymatic efficiency
-
10.1097/QAD.0b013e328318f16c, 19005273
-
Harrigan PR, Sheen CW, Gill VS, Wynhoven B, Hudson E, Lima VD, Lecocq P, Aguirre R, Poon AF, Sluis-Cremer N. Silent mutations are selected in HIV-1 reverse transcriptase and affect enzymatic efficiency. AIDS 2008, 22:2501-2508. 10.1097/QAD.0b013e328318f16c, 19005273.
-
(2008)
AIDS
, vol.22
, pp. 2501-2508
-
-
Harrigan, P.R.1
Sheen, C.W.2
Gill, V.S.3
Wynhoven, B.4
Hudson, E.5
Lima, V.D.6
Lecocq, P.7
Aguirre, R.8
Poon, A.F.9
Sluis-Cremer, N.10
-
38
-
-
77956228894
-
HIV-1 subtype B and C integrase enzymes exhibit differential patterns of resistance to integrase inhibitors in biochemical assays
-
Bar-Magen T, Donahue DA, McDonough EI, Kuhl BD, Faltenbacher VH, Xu H, Michaud V, Sloan RD, Wainberg MA. HIV-1 subtype B and C integrase enzymes exhibit differential patterns of resistance to integrase inhibitors in biochemical assays. AIDS 2010,
-
(2010)
AIDS
-
-
Bar-Magen, T.1
Donahue, D.A.2
McDonough, E.I.3
Kuhl, B.D.4
Faltenbacher, V.H.5
Xu, H.6
Michaud, V.7
Sloan, R.D.8
Wainberg, M.A.9
-
39
-
-
77953764574
-
HIV-1 protease codon 36 polymorphisms and differential development of resistance to nelfinavir, lopinavir, and atazanavir in different HIV-1 subtypes
-
10.1128/AAC.01828-09, 20404123
-
Lisovsky I, Schader SM, Martinez-Cajas JL, Oliveira M, Moisi D, Wainberg MA. HIV-1 protease codon 36 polymorphisms and differential development of resistance to nelfinavir, lopinavir, and atazanavir in different HIV-1 subtypes. Antimicrob Agents Chemother 2010, 54:2878-2885. 10.1128/AAC.01828-09, 20404123.
-
(2010)
Antimicrob Agents Chemother
, vol.54
, pp. 2878-2885
-
-
Lisovsky, I.1
Schader, S.M.2
Martinez-Cajas, J.L.3
Oliveira, M.4
Moisi, D.5
Wainberg, M.A.6
-
40
-
-
0028176053
-
Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction
-
Arts EJ, Li X, Gu Z, Kleiman L, Parniak MA, Wainberg MA. Comparison of deoxyoligonucleotide and tRNA(Lys-3) as primers in an endogenous human immunodeficiency virus-1 in vitro reverse transcription/template-switching reaction. J Biol Chem 1994, 269:14672-14680.
-
(1994)
J Biol Chem
, vol.269
, pp. 14672-14680
-
-
Arts, E.J.1
Li, X.2
Gu, Z.3
Kleiman, L.4
Parniak, M.A.5
Wainberg, M.A.6
-
41
-
-
61549120158
-
Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance
-
2644664, 19210791
-
Xu HT, Martinez-Cajas JL, Ntemgwa ML, Coutsinos D, Frankel FA, Brenner BG, Wainberg MA. Effects of the K65R and K65R/M184V reverse transcriptase mutations in subtype C HIV on enzyme function and drug resistance. Retrovirology 2009, 6:14. 2644664, 19210791.
-
(2009)
Retrovirology
, vol.6
, pp. 14
-
-
Xu, H.T.1
Martinez-Cajas, J.L.2
Ntemgwa, M.L.3
Coutsinos, D.4
Frankel, F.A.5
Brenner, B.G.6
Wainberg, M.A.7
-
42
-
-
0141705300
-
Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C
-
10.1089/088922203769232548, 14585205
-
Quan Y, Brenner BG, Marlink RG, Essex M, Kurimura T, Wainberg MA. Drug resistance profiles of recombinant reverse transcriptases from human immunodeficiency virus type 1 subtypes A/E, B, and C. AIDS Res Hum Retroviruses 2003, 19:743-753. 10.1089/088922203769232548, 14585205.
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, pp. 743-753
-
-
Quan, Y.1
Brenner, B.G.2
Marlink, R.G.3
Essex, M.4
Kurimura, T.5
Wainberg, M.A.6
-
43
-
-
0032875344
-
Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val
-
112864, 10482597
-
Sharma PL, Crumpacker CS. Decreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val. J Virol 1999, 73:8448-8456. 112864, 10482597.
-
(1999)
J Virol
, vol.73
, pp. 8448-8456
-
-
Sharma, P.L.1
Crumpacker, C.S.2
-
44
-
-
0026448638
-
Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activities
-
10.1073/pnas.89.22.10763, 50422, 1279694
-
Gopalakrishnan V, Peliska JA, Benkovic SJ. Human immunodeficiency virus type 1 reverse transcriptase: spatial and temporal relationship between the polymerase and RNase H activities. Proc Natl Acad Sci USA 1992, 89:10763-10767. 10.1073/pnas.89.22.10763, 50422, 1279694.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 10763-10767
-
-
Gopalakrishnan, V.1
Peliska, J.A.2
Benkovic, S.J.3
-
45
-
-
33845917770
-
Reduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer
-
10.1074/jbc.M604665200, 16926150
-
Operario DJ, Balakrishnan M, Bambara RA, Kim B. Reduced dNTP interaction of human immunodeficiency virus type 1 reverse transcriptase promotes strand transfer. J Biol Chem 2006, 281:32113-32121. 10.1074/jbc.M604665200, 16926150.
-
(2006)
J Biol Chem
, vol.281
, pp. 32113-32121
-
-
Operario, D.J.1
Balakrishnan, M.2
Bambara, R.A.3
Kim, B.4
|