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Volumn 22, Issue 10, 2010, Pages 797-803

Making memories that last a lifetime: Heritable functions of self-renewing memory CD8 T cells

Author keywords

CD8 T cell; Epigenetic; Immune memory; Infection; T cell differentiation

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; GAMMA INTERFERON; TRANSCRIPTION FACTOR;

EID: 77957339221     PISSN: 09538178     EISSN: 14602377     Source Type: Journal    
DOI: 10.1093/intimm/dxq437     Document Type: Review
Times cited : (38)

References (77)
  • 1
    • 2442684151 scopus 로고    scopus 로고
    • Memory CD8 T-cell differentiation during viral infection
    • Wherry, E. J. and Ahmed, R. 2004. Memory CD8 T-cell differentiation during viral infection. J. Virol. 78:5535.
    • (2004) J. Virol. , vol.78 , pp. 5535
    • Wherry, E.J.1    Ahmed, R.2
  • 2
    • 0030001674 scopus 로고    scopus 로고
    • Immunological memory and protective immunity: understanding their relation
    • Ahmed, R. and Gray, D. 1996. Immunological memory and protective immunity: understanding their relation. Science 272:54.
    • (1996) Science , vol.272 , pp. 54
    • Ahmed, R.1    Gray, D.2
  • 3
    • 0034192425 scopus 로고    scopus 로고
    • T-cell memory: you must remember this
    • Bevan, M. J. and Goldrath, A. W. 2000. T-cell memory: you must remember this. Curr. Biol. 10:R338.
    • (2000) Curr. Biol. , vol.10
    • Bevan, M.J.1    Goldrath, A.W.2
  • 4
    • 0029665304 scopus 로고    scopus 로고
    • Establishment and persistence of virus-specific CD4+ and CD8+ T cell memory
    • Doherty, P. C., Topham, D. J. and Tripp, R. A. 1996. Establishment and persistence of virus-specific CD4+ and CD8+ T cell memory. Immunol. Rev. 150:23.
    • (1996) Immunol. Rev. , vol.150 , pp. 23
    • Doherty, P.C.1    Topham, D.J.2    Tripp, R.A.3
  • 5
    • 0036668248 scopus 로고    scopus 로고
    • T cell immunity in lymphoid and non-lymphoid tissues
    • Lefrancois, L. and Masopust, D. 2002. T cell immunity in lymphoid and non-lymphoid tissues. Curr. Opin. Immunol. 14:503.
    • (2002) Curr. Opin. Immunol. , vol.14 , pp. 503
    • Lefrancois, L.1    Masopust, D.2
  • 6
    • 67049136157 scopus 로고    scopus 로고
    • Diversity in CD8(+) T cell differentiation
    • Parish, I. A. and Kaech, S. M. 2009. Diversity in CD8(+) T cell differentiation. Curr. Opin. Immunol. 21:291.
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 291
    • Parish, I.A.1    Kaech, S.M.2
  • 7
    • 0041381363 scopus 로고    scopus 로고
    • Similarities and differences in CD4+ and CD8+ effector and memory T cell generation
    • Seder, R. A. and Ahmed, R. 2003. Similarities and differences in CD4+ and CD8+ effector and memory T cell generation. Nat. Immunol. 4:835.
    • (2003) Nat. Immunol. , vol.4 , pp. 835
    • Seder, R.A.1    Ahmed, R.2
  • 8
    • 43449132462 scopus 로고    scopus 로고
    • The effector to memory transition of CD4 T cells
    • McKinstry, K. K., Strutt, T. M. and Swain, S. L. 2008. The effector to memory transition of CD4 T cells. Immunol. Res. 40:114.
    • (2008) Immunol. Res. , vol.40 , pp. 114
    • McKinstry, K.K.1    Strutt, T.M.2    Swain, S.L.3
  • 9
    • 70249100293 scopus 로고    scopus 로고
    • Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity
    • Sallusto, F. and Lanzavecchia, A. 2009. Heterogeneity of CD4+ memory T cells: functional modules for tailored immunity. Eur. J. Immunol. 39:2076.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 2076
    • Sallusto, F.1    Lanzavecchia, A.2
  • 10
    • 0032005477 scopus 로고    scopus 로고
    • Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection
    • Murali-Krishna, K., Altman, J. D., Suresh, M. et al. 1998. Counting antigen-specific CD8 T cells: a reevaluation of bystander activation during viral infection. Immunity 8:177.
    • (1998) Immunity , vol.8 , pp. 177
    • Murali-Krishna, K.1    Altman, J.D.2    Suresh, M.3
  • 11
    • 0037018098 scopus 로고    scopus 로고
    • Estimating the precursor frequency of naive antigen-specific CD8 T cells
    • Blattman, J. N., Antia, R., Sourdive, D. J. et al. 2002. Estimating the precursor frequency of naive antigen-specific CD8 T cells. J. Exp. Med. 195:657.
    • (2002) J. Exp. Med. , vol.195 , pp. 657
    • Blattman, J.N.1    Antia, R.2    Sourdive, D.J.3
  • 12
    • 0033548496 scopus 로고    scopus 로고
    • Linear differentiation of cytotoxic effectors into memory T lymphocytes
    • Opferman, J. T., Ober, B. T. and Ashton-Rickardt, P. G. 1999. Linear differentiation of cytotoxic effectors into memory T lymphocytes. Science 283:1745.
    • (1999) Science , vol.283 , pp. 1745
    • Opferman, J.T.1    Ober, B.T.2    Ashton-Rickardt, P.G.3
  • 13
    • 0033542458 scopus 로고    scopus 로고
    • Modelling T-cell memory by genetic marking of memory T cells in vivo
    • Jacob, J. and Baltimore, D. 1999. Modelling T-cell memory by genetic marking of memory T cells in vivo. Nature 399:593.
    • (1999) Nature , vol.399 , pp. 593
    • Jacob, J.1    Baltimore, D.2
  • 14
    • 58849126149 scopus 로고    scopus 로고
    • Secondary replicative function of CD8+ T cells that had developed an effector phenotype
    • Bannard, O., Kraman, M. and Fearon, D. T. 2009. Secondary replicative function of CD8+ T cells that had developed an effector phenotype. Science 323:505.
    • (2009) Science , vol.323 , pp. 505
    • Bannard, O.1    Kraman, M.2    Fearon, D.T.3
  • 15
    • 0347382593 scopus 로고    scopus 로고
    • Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
    • Kaech, S. M., Tan, J. T., Wherry, E. J., Konieczny, B. T., Surh, C. D. and Ahmed, R. 2003. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat. Immunol. 4:1191.
    • (2003) Nat. Immunol. , vol.4 , pp. 1191
    • Kaech, S.M.1    Tan, J.T.2    Wherry, E.J.3    Konieczny, B.T.4    Surh, C.D.5    Ahmed, R.6
  • 16
    • 74549162832 scopus 로고    scopus 로고
    • Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo
    • Kalia, V., Sarkar, S., Subramaniam, S., Haining, W. N., Smith, K. A. and Ahmed, R. 2010. Prolonged interleukin-2Ralpha expression on virus-specific CD8+ T cells favors terminal-effector differentiation in vivo. Immunity 32:91.
    • (2010) Immunity , vol.32 , pp. 91
    • Kalia, V.1    Sarkar, S.2    Subramaniam, S.3    Haining, W.N.4    Smith, K.A.5    Ahmed, R.6
  • 17
    • 41149099559 scopus 로고    scopus 로고
    • Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates
    • Sarkar, S., Kalia, V., Haining, W. N., Konieczny, B. T., Subramaniam, S. and Ahmed, R. 2008. Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates. J. Exp. Med. 205:625.
    • (2008) J. Exp. Med. , vol.205 , pp. 625
    • Sarkar, S.1    Kalia, V.2    Haining, W.N.3    Konieczny, B.T.4    Subramaniam, S.5    Ahmed, R.6
  • 18
    • 33947730608 scopus 로고    scopus 로고
    • Asymmetric T lymphocyte division in the initiation of adaptive immune responses
    • Chang, J. T., Palanivel, V. R., Kinjyo, I. et al. 2007. Asymmetric T lymphocyte division in the initiation of adaptive immune responses. Science 315:1687.
    • (2007) Science , vol.315 , pp. 1687
    • Chang, J.T.1    Palanivel, V.R.2    Kinjyo, I.3
  • 19
    • 0037340417 scopus 로고    scopus 로고
    • Lineage relationship and protective immunity of memory CD8 T cell subsets
    • Wherry, E. J., Teichgraber, V., Becker, T. C. et al. 2003. Lineage relationship and protective immunity of memory CD8 T cell subsets. Nat. Immunol. 4:225.
    • (2003) Nat. Immunol. , vol.4 , pp. 225
    • Wherry, E.J.1    Teichgraber, V.2    Becker, T.C.3
  • 20
    • 33646058925 scopus 로고    scopus 로고
    • Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells
    • Kersh, E. N., Fitzpatrick, D. R., Murali-Krishna, K. et al. 2006. Rapid demethylation of the IFN-gamma gene occurs in memory but not naive CD8 T cells. J. Immunol. 176:4083.
    • (2006) J. Immunol. , vol.176 , pp. 4083
    • Kersh, E.N.1    Fitzpatrick, D.R.2    Murali-Krishna, K.3
  • 21
    • 0032921486 scopus 로고    scopus 로고
    • Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection
    • Bachmann, M. F., Barner, M., Viola, A. and Kopf, M. 1999. Distinct kinetics of cytokine production and cytolysis in effector and memory T cells after viral infection. Eur. J. Immunol. 29:291.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 291
    • Bachmann, M.F.1    Barner, M.2    Viola, A.3    Kopf, M.4
  • 22
    • 0345654347 scopus 로고    scopus 로고
    • Kinetics of the response of naive and memory CD8 T cells to antigen: similarities and differences
    • Zimmermann, C., Prevost-Blondel, A., Blaser, C. and Pircher, H. 1999. Kinetics of the response of naive and memory CD8 T cells to antigen: similarities and differences. Eur. J. Immunol. 29:284.
    • (1999) Eur. J. Immunol. , vol.29 , pp. 284
    • Zimmermann, C.1    Prevost-Blondel, A.2    Blaser, C.3    Pircher, H.4
  • 23
    • 0034887110 scopus 로고    scopus 로고
    • Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory
    • Homann, D., Teyton, L. and Oldstone, M. B. 2001. Differential regulation of antiviral T-cell immunity results in stable CD8+ but declining CD4+ T-cell memory. Nat. Med. 7:913.
    • (2001) Nat. Med. , vol.7 , pp. 913
    • Homann, D.1    Teyton, L.2    Oldstone, M.B.3
  • 25
    • 2342584151 scopus 로고    scopus 로고
    • Immunological memory in humans
    • Crotty, S. and Ahmed, R. 2004. Immunological memory in humans. Semin. Immunol. 16:197.
    • (2004) Semin. Immunol. , vol.16 , pp. 197
    • Crotty, S.1    Ahmed, R.2
  • 26
    • 0034889233 scopus 로고    scopus 로고
    • Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR
    • Slifka, M. K. and Whitton, J. L. 2001. Functional avidity maturation of CD8(+) T cells without selection of higher affinity TCR. Nat. Immunol. 2:711.
    • (2001) Nat. Immunol. , vol.2 , pp. 711
    • Slifka, M.K.1    Whitton, J.L.2
  • 27
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • Kaech, S. M., Hemby, S., Kersh, E. and Ahmed, R. 2002. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111:837.
    • (2002) Cell , vol.111 , pp. 837
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 28
    • 35349014587 scopus 로고    scopus 로고
    • Molecular signature of CD8 T cell exhaustion during chronic viral infection
    • Wherry, E. J., Ha, S., Kaech, S. M. et al. 2007. Molecular signature of CD8 T cell exhaustion during chronic viral infection. Immunity 27:670.
    • (2007) Immunity , vol.27 , pp. 670
    • Wherry, E.J.1    Ha, S.2    Kaech, S.M.3
  • 29
    • 27144467425 scopus 로고    scopus 로고
    • Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets
    • Willinger, T., Freeman, T., Hasegawa, H., McMichael, A. J. and Callan, M. F. 2005. Molecular signatures distinguish human central memory from effector memory CD8 T cell subsets. J. Immunol. 175:5895.
    • (2005) J. Immunol. , vol.175 , pp. 5895
    • Willinger, T.1    Freeman, T.2    Hasegawa, H.3    McMichael, A.J.4    Callan, M.F.5
  • 30
    • 33751184610 scopus 로고    scopus 로고
    • Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response
    • Fann, M., Godlove, J. M., Catalfamo, M. et al. 2006. Histone acetylation is associated with differential gene expression in the rapid and robust memory CD8(+) T-cell response. Blood 108:3363.
    • (2006) Blood , vol.108 , pp. 3363
    • Fann, M.1    Godlove, J.M.2    Catalfamo, M.3
  • 31
    • 0025855079 scopus 로고
    • The myoD gene family: nodal point during specification of the muscle cell lineage
    • Weintraub, H., Davis, R., Tapscott, S. et al. 1991. The myoD gene family: nodal point during specification of the muscle cell lineage. Science 251:761.
    • (1991) Science , vol.251 , pp. 761
    • Weintraub, H.1    Davis, R.2    Tapscott, S.3
  • 32
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori, S., Nomura, T. and Sakaguchi, S. 2003. Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057.
    • (2003) Science , vol.299 , pp. 1057
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 33
    • 34247277666 scopus 로고    scopus 로고
    • Foxp3 in control of the regulatory T cell lineage
    • Zheng, Y. and Rudensky, A. Y. 2007. Foxp3 in control of the regulatory T cell lineage. Nat. Immunol. 8:457.
    • (2007) Nat. Immunol. , vol.8 , pp. 457
    • Zheng, Y.1    Rudensky, A.Y.2
  • 34
    • 0036078187 scopus 로고    scopus 로고
    • Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells
    • Ichii, H., Sakamoto, A., Hatano, M. et al. 2002. Role for Bcl-6 in the generation and maintenance of memory CD8+ T cells. Nat. Immunol. 3:558.
    • (2002) Nat. Immunol. , vol.3 , pp. 558
    • Ichii, H.1    Sakamoto, A.2    Hatano, M.3
  • 35
    • 30044440799 scopus 로고    scopus 로고
    • Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin
    • Intlekofer, A. M., Takemoto, N., Wherry, E. J. et al. 2005. Effector and memory CD8+ T cell fate coupled by T-bet and eomesodermin. Nat. Immunol. 6:1236.
    • (2005) Nat. Immunol. , vol.6 , pp. 1236
    • Intlekofer, A.M.1    Takemoto, N.2    Wherry, E.J.3
  • 36
    • 33846305724 scopus 로고    scopus 로고
    • Transcriptional regulator Id2 mediates CD8+ T cell immunity
    • Cannarile, M. A., Lind, N. A., Rivera, R. et al. 2006. Transcriptional regulator Id2 mediates CD8+ T cell immunity. Nat. Immunol. 7:1317.
    • (2006) Nat. Immunol. , vol.7 , pp. 1317
    • Cannarile, M.A.1    Lind, N.A.2    Rivera, R.3
  • 37
    • 68649111205 scopus 로고    scopus 로고
    • Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties
    • Rutishauser, R. L., Martins, G. A., Kalachikov, S. et al. 2009. Transcriptional repressor Blimp-1 promotes CD8(+) T cell terminal differentiation and represses the acquisition of central memory T cell properties. Immunity 31:296.
    • (2009) Immunity , vol.31 , pp. 296
    • Rutishauser, R.L.1    Martins, G.A.2    Kalachikov, S.3
  • 38
    • 68649096424 scopus 로고    scopus 로고
    • A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection
    • Shin, H., Blackburn, S. D., Intlekofer, A. M. et al. 2009. A role for the transcriptional repressor Blimp-1 in CD8(+) T cell exhaustion during chronic viral infection. Immunity 31:309.
    • (2009) Immunity , vol.31 , pp. 309
    • Shin, H.1    Blackburn, S.D.2    Intlekofer, A.M.3
  • 39
    • 75649136214 scopus 로고    scopus 로고
    • Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation
    • Crotty, S., Johnston, R. J. and Schoenberger, S. P. 2010. Effectors and memories: Bcl-6 and Blimp-1 in T and B lymphocyte differentiation. Nat. Immunol. 11:114.
    • (2010) Nat. Immunol. , vol.11 , pp. 114
    • Crotty, S.1    Johnston, R.J.2    Schoenberger, S.P.3
  • 40
    • 0036144048 scopus 로고    scopus 로고
    • DNA methylation patterns and epigenetic memory
    • Bird, A. 2002. DNA methylation patterns and epigenetic memory. Genes Dev. 16:6.
    • (2002) Genes Dev , vol.16 , pp. 6
    • Bird, A.1
  • 41
    • 34249299791 scopus 로고    scopus 로고
    • The complex language of chromatin regulation during transcription
    • Berger, S. L. 2007. The complex language of chromatin regulation during transcription. Nature 447:407.
    • (2007) Nature , vol.447 , pp. 407
    • Berger, S.L.1
  • 42
    • 0038638583 scopus 로고    scopus 로고
    • An epigenetic view of helper T cell differentiation
    • Ansel, K. M., Lee, D. U. and Rao, A. 2003. An epigenetic view of helper T cell differentiation. Nat. Immunol. 4:616.
    • (2003) Nat. Immunol. , vol.4 , pp. 616
    • Ansel, K.M.1    Lee, D.U.2    Rao, A.3
  • 43
    • 58849092225 scopus 로고    scopus 로고
    • Epigenetic control of T-helper-cell differentiation
    • Wilson, C. B., Rowell, E. and Sekimata, M. 2009. Epigenetic control of T-helper-cell differentiation. Nat. Rev. Immunol. 9:91.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 91
    • Wilson, C.B.1    Rowell, E.2    Sekimata, M.3
  • 44
    • 0036733675 scopus 로고    scopus 로고
    • Chromatin modification and epigenetic reprogramming in mammalian development
    • Li, E. 2002. Chromatin modification and epigenetic reprogramming in mammalian development. Nat. Rev. Genet. 3:662.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 662
    • Li, E.1
  • 45
    • 33845417885 scopus 로고    scopus 로고
    • The cancer epigenome-components and functional correlates
    • Ting, A. H., McGarvey, K. M. and Baylin, S. B. 2006. The cancer epigenome-components and functional correlates. Genes Dev. 20:3215.
    • (2006) Genes Dev , vol.20 , pp. 3215
    • Ting, A.H.1    McGarvey, K.M.2    Baylin, S.B.3
  • 46
    • 34249279527 scopus 로고    scopus 로고
    • Stability and flexibility of epigenetic gene regulation in mammalian development
    • Reik, W. 2007. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 447:425.
    • (2007) Nature , vol.447 , pp. 425
    • Reik, W.1
  • 47
    • 0037007175 scopus 로고    scopus 로고
    • Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases
    • Jeltsch, A. 2002. Beyond Watson and Crick: DNA methylation and molecular enzymology of DNA methyltransferases. Chembiochem 3:274.
    • (2002) Chembiochem , vol.3 , pp. 274
    • Jeltsch, A.1
  • 48
    • 0034610814 scopus 로고    scopus 로고
    • The language of covalent histone modifications
    • Strahl, B. D. and Allis, C. D. 2000. The language of covalent histone modifications. Nature 403:41.
    • (2000) Nature , vol.403 , pp. 41
    • Strahl, B.D.1    Allis, C.D.2
  • 49
    • 77950678085 scopus 로고    scopus 로고
    • Coordinated chromatin control: structural and functional linkage of DNA and histone methylation
    • Cheng, X. and Blumenthal, R. M. 2010. Coordinated chromatin control: structural and functional linkage of DNA and histone methylation. Biochemistry 49:2999.
    • (2010) Biochemistry , vol.49 , pp. 2999
    • Cheng, X.1    Blumenthal, R.M.2
  • 50
    • 0037068372 scopus 로고    scopus 로고
    • DNA methylation and chromatin-unraveling the tangled web
    • Robertson, K. D. 2002. DNA methylation and chromatin-unraveling the tangled web. Oncogene 21:5361.
    • (2002) Oncogene , vol.21 , pp. 5361
    • Robertson, K.D.1
  • 51
    • 0037356316 scopus 로고    scopus 로고
    • Epigenetics in carcinogenesis and cancer prevention
    • Jones, P. A. 2003. Epigenetics in carcinogenesis and cancer prevention. Ann. N. Y. Acad. Sci. 983:213.
    • (2003) Ann. N. Y. Acad. Sci. , vol.983 , pp. 213
    • Jones, P.A.1
  • 52
    • 0036274359 scopus 로고    scopus 로고
    • The fundamental role of epigenetic events in cancer
    • Jones, P. A. and Baylin, S. B. 2002. The fundamental role of epigenetic events in cancer. Nat. Rev. Genet. 3:415.
    • (2002) Nat. Rev. Genet. , vol.3 , pp. 415
    • Jones, P.A.1    Baylin, S.B.2
  • 53
    • 0031667275 scopus 로고    scopus 로고
    • Role of the ras-MAPK signaling pathway in the DNA methyltransferase response to DNA hypomethylation
    • Deng, C., Yang, J., Scott, J., Hanash, S. and Richardson, B. C. 1998. Role of the ras-MAPK signaling pathway in the DNA methyltransferase response to DNA hypomethylation. Biol. Chem. 379:1113.
    • (1998) Biol. Chem. , vol.379 , pp. 1113
    • Deng, C.1    Yang, J.2    Scott, J.3    Hanash, S.4    Richardson, B.C.5
  • 54
    • 75749090357 scopus 로고    scopus 로고
    • Key role of ERK pathway signaling in lupus
    • Gorelik, G. and Richardson, B. 2010. Key role of ERK pathway signaling in lupus. Autoimmunity 43:17.
    • (2010) Autoimmunity , vol.43 , pp. 17
    • Gorelik, G.1    Richardson, B.2
  • 55
    • 73849094364 scopus 로고    scopus 로고
    • Quick to remember, slow to forget: rapid recall responses of memory CD8+ T cells
    • DiSpirito, J. R. and Shen, H. 2010. Quick to remember, slow to forget: rapid recall responses of memory CD8+ T cells. Cell Res. 20:13.
    • (2010) Cell Res , vol.20 , pp. 13
    • DiSpirito, J.R.1    Shen, H.2
  • 56
    • 77954462446 scopus 로고    scopus 로고
    • Histone acetylation at the single-cell level: a marker of memory CD8(+) T cell differentiation and functionality
    • Dispirito, J. R. and Shen, H. 2010. Histone acetylation at the single-cell level: a marker of memory CD8(+) T cell differentiation and functionality. J. Immunol. 184:4631.
    • (2010) J. Immunol. , vol.184 , pp. 4631
    • Dispirito, J.R.1    Shen, H.2
  • 57
    • 50949127683 scopus 로고    scopus 로고
    • Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B)
    • Araki, Y., Fann, M., Wersto, R. and Weng, N. P. 2008. Histone acetylation facilitates rapid and robust memory CD8 T cell response through differential expression of effector molecules (eomesodermin and its targets: perforin and granzyme B). J. Immunol. 180:8102.
    • (2008) J. Immunol. , vol.180 , pp. 8102
    • Araki, Y.1    Fann, M.2    Wersto, R.3    Weng, N.P.4
  • 58
    • 33847076248 scopus 로고    scopus 로고
    • Chromatin challenges during DNA replication and repair
    • Groth, A., Rocha, W., Verreault, A. and Almouzni, G. 2007. Chromatin challenges during DNA replication and repair. Cell 128:721.
    • (2007) Cell , vol.128 , pp. 721
    • Groth, A.1    Rocha, W.2    Verreault, A.3    Almouzni, G.4
  • 59
    • 0030006949 scopus 로고    scopus 로고
    • Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences
    • Flynn, J., Glickman, J. F. and Reich, N. O. 1996. Murine DNA cytosine-C5 methyltransferase: pre-steady- and steady-state kinetic analysis with regulatory DNA sequences. Biochemistry 35:7308.
    • (1996) Biochemistry , vol.35 , pp. 7308
    • Flynn, J.1    Glickman, J.F.2    Reich, N.O.3
  • 60
    • 70350046301 scopus 로고    scopus 로고
    • Rethinking how DNA methylation patterns are maintained
    • Jones, P. A. and Liang, G. 2009. Rethinking how DNA methylation patterns are maintained. Nat. Rev. Genet. 10:805.
    • (2009) Nat. Rev. Genet. , vol.10 , pp. 805
    • Jones, P.A.1    Liang, G.2
  • 61
    • 0029094182 scopus 로고
    • Mammalian DNA (cytosine-5-)-methyltransferase expressed in Escherichia coli, purified and characterized
    • Tollefsbol, T. O. and Hutchison, C. A., 3rd 1995. Mammalian DNA (cytosine-5-)-methyltransferase expressed in Escherichia coli, purified and characterized. J. Biol. Chem. 270:18543.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18543
    • Tollefsbol, T.O.1    Hutchison C.A.3rd2
  • 62
    • 0034665756 scopus 로고    scopus 로고
    • X inactivation in the mouse embryo deficient for Dnmt1: distinct effect of hypomethylation on imprinted and random X inactivation
    • Sado, T., Fenner, M. H., Tan, S. S., Tam, P., Shioda, T. and Li, E. 2000. X inactivation in the mouse embryo deficient for Dnmt1: distinct effect of hypomethylation on imprinted and random X inactivation. Dev. Biol. 225:294.
    • (2000) Dev. Biol. , vol.225 , pp. 294
    • Sado, T.1    Fenner, M.H.2    Tan, S.S.3    Tam, P.4    Shioda, T.5    Li, E.6
  • 63
    • 33645770934 scopus 로고    scopus 로고
    • DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion
    • Chappell, C., Beard, C., Altman, J., Jaenisch, R. and Jacob, J. 2006. DNA methylation by DNA methyltransferase 1 is critical for effector CD8 T cell expansion. J. Immunol. 176:4562.
    • (2006) J. Immunol. , vol.176 , pp. 4562
    • Chappell, C.1    Beard, C.2    Altman, J.3    Jaenisch, R.4    Jacob, J.5
  • 64
    • 18244365863 scopus 로고    scopus 로고
    • A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival
    • Lee, P. P., Fitzpatrick, D. R., Beard, C. et al. 2001. A critical role for Dnmt1 and DNA methylation in T cell development, function, and survival. Immunity 15:763.
    • (2001) Immunity , vol.15 , pp. 763
    • Lee, P.P.1    Fitzpatrick, D.R.2    Beard, C.3
  • 65
    • 65549100376 scopus 로고    scopus 로고
    • Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1
    • Josefowicz, S. Z., Wilson, C. B. and Rudensky, A. Y. 2009. Cutting edge: TCR stimulation is sufficient for induction of Foxp3 expression in the absence of DNA methyltransferase 1. J. Immunol. 182:6648.
    • (2009) J. Immunol. , vol.182 , pp. 6648
    • Josefowicz, S.Z.1    Wilson, C.B.2    Rudensky, A.Y.3
  • 66
    • 33748502968 scopus 로고    scopus 로고
    • Impaired memory CD8 T cell development in the absence of methyl-CpG-binding domain protein 2
    • Kersh, E. N. 2006. Impaired memory CD8 T cell development in the absence of methyl-CpG-binding domain protein 2. J. Immunol. 177:3821.
    • (2006) J. Immunol. , vol.177 , pp. 3821
    • Kersh, E.N.1
  • 67
    • 33745861718 scopus 로고    scopus 로고
    • Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells
    • Northrop, J. K., Thomas, R. M., Wells, A. D. and Shen, H. 2006. Epigenetic remodeling of the IL-2 and IFN-gamma loci in memory CD8 T cells is influenced by CD4 T cells. J. Immunol. 177:1062.
    • (2006) J. Immunol. , vol.177 , pp. 1062
    • Northrop, J.K.1    Thomas, R.M.2    Wells, A.D.3    Shen, H.4
  • 68
    • 0037074012 scopus 로고    scopus 로고
    • Molecular and functional profiling of memory CD8 T cell differentiation
    • Kaech, S. M., Hemby, S., Kersh, E. and Ahmed, R. 2002. Molecular and functional profiling of memory CD8 T cell differentiation. Cell 111:837.
    • (2002) Cell , vol.111 , pp. 837
    • Kaech, S.M.1    Hemby, S.2    Kersh, E.3    Ahmed, R.4
  • 69
    • 73349112246 scopus 로고    scopus 로고
    • Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression
    • Juelich, T., Sutcliffe, E. L., Denton, A. et al. 2009. Interplay between chromatin remodeling and epigenetic changes during lineage-specific commitment to granzyme B expression. J. Immunol. 183:7063.
    • (2009) J. Immunol. , vol.183 , pp. 7063
    • Juelich, T.1    Sutcliffe, E.L.2    Denton, A.3
  • 70
    • 33644646837 scopus 로고    scopus 로고
    • Chromatin structure and gene regulation in T cell development and function
    • Wilson, C. B. and Merkenschlager, M. 2006. Chromatin structure and gene regulation in T cell development and function. Curr. Opin. Immunol. 18:143.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 143
    • Wilson, C.B.1    Merkenschlager, M.2
  • 71
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu, J., Yamane, H. and Paul, W. E. 2010. Differentiation of effector CD4 T cell populations (*). Annu. Rev. Immunol. 28:445.
    • (2010) Annu. Rev. Immunol. , vol.28 , pp. 445
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 72
    • 0036345455 scopus 로고    scopus 로고
    • Gene silencing quantitatively controls the function of a developmental trans-activator
    • Hutchins, A. S., Mullen, A. C., Lee, H. W. et al. 2002. Gene silencing quantitatively controls the function of a developmental trans-activator. Mol. Cell. 10:81.
    • (2002) Mol. Cell. , vol.10 , pp. 81
    • Hutchins, A.S.1    Mullen, A.C.2    Lee, H.W.3
  • 73
    • 34250773899 scopus 로고    scopus 로고
    • Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma
    • Schoenborn, J. R., Dorschner, M. O., Sekimata, M. et al. 2007. Comprehensive epigenetic profiling identifies multiple distal regulatory elements directing transcription of the gene encoding interferon-gamma. Nat. Immunol. 8:732.
    • (2007) Nat. Immunol. , vol.8 , pp. 732
    • Schoenborn, J.R.1    Dorschner, M.O.2    Sekimata, M.3
  • 74
    • 0032412441 scopus 로고    scopus 로고
    • Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation
    • Agarwal, S. and Rao, A. 1998. Modulation of chromatin structure regulates cytokine gene expression during T cell differentiation. Immunity 9:765.
    • (1998) Immunity , vol.9 , pp. 765
    • Agarwal, S.1    Rao, A.2
  • 75
    • 76749133610 scopus 로고    scopus 로고
    • Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate
    • Zheng, Y., Josefowicz, S., Chaudhry, A., Peng, X. P., Forbush, K. and Rudensky, A. Y. 2010. Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate. Nature 463:808.
    • (2010) Nature , vol.463 , pp. 808
    • Zheng, Y.1    Josefowicz, S.2    Chaudhry, A.3    Peng, X.P.4    Forbush, K.5    Rudensky, A.Y.6
  • 76
    • 71149106263 scopus 로고    scopus 로고
    • Switching on epigenetic therapy
    • Karberg, S. 2009. Switching on epigenetic therapy. Cell 139:1029.
    • (2009) Cell , vol.139 , pp. 1029
    • Karberg, S.1
  • 77
    • 35948980739 scopus 로고    scopus 로고
    • Deacetylase inhibition promotes the generation and function of regulatory T cells
    • Tao, R., de Zoeten, E. F., Ozkaynak, E. et al. 2007. Deacetylase inhibition promotes the generation and function of regulatory T cells. Nat. Med. 13:1299.
    • (2007) Nat. Med. , vol.13 , pp. 1299
    • Tao, R.1    de Zoeten, E.F.2    Ozkaynak, E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.