Poly(ADP-Ribose) polymerase inhibition reverses nitrergic neurovascular dysfunctions in penile erectile tissue from streptozotocin-diabetic mice

Journal of Sexual Medicine

Volumn 7, Issue 10, 2010, Pages 3396-3403

  Nangle, Matthew R ^a,b   Cotter, Mary A ^a   Cameron, Norman E ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

^b UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Diabetes and Erectile Dysfunction; Diabetic Neuropathy; Endothelial Dysfunction; Oxidative Stress; Peroxynitrite; Poly(ADP ribose) Polymerase (PARP)

Indexed keywords

10 (4 METHYLPIPERAZIN 1 YLMETHYL) 2H 7 OXA 1,2 DIAZABENZO[DE]ANTHRACEN 3 ONE; ACETYLCHOLINE; GPI 15427; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; NITRIC OXIDE; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORPUS CAVERNOSUM; DIABETES MELLITUS; DIABETIC NEUROPATHY; DRUG SENSITIVITY; ENDOTHELIAL DYSFUNCTION; ENZYME INHIBITION; ERECTILE DYSFUNCTION; EVOKED RESPONSE; MALE; MOUSE; MOUSE STRAIN; NEUROMUSCULAR ELECTRICAL STIMULATION; NITRERGIC NERVE; NONHUMAN; OXIDATIVE STRESS; PENIS; PRIORITY JOURNAL; SMOOTH MUSCLE CONTRACTION; SMOOTH MUSCLE RELAXATION; SMOOTH MUSCLE TONE; STREPTOZOCIN DIABETES;

EID: 77957332423     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2010.01835.x     Document Type: Article

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