Synthesis and in vitro anti-hepatitis B virus activity of 1H-benzimidazol-5-ol derivatives

Chinese Chemical Letters

Volumn 21, Issue 11, 2010, Pages 1326-1329

  Chen, Dong ^a   Zhai, Xin ^a   Yuan, Qiu Hui ^a   Luo, Jian ^a   Xie, Si Chang ^a   Gong, Ping ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

1H benzimidazol 5 ol; Anti HBV activity; Synthesis

Indexed keywords

EID: 77957242121     PISSN: 10018417     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cclet.2010.05.011     Document Type: Article

References (11)

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11. -1): 3421.6, 3142.4, 2960.4, 1604.2, 1559.7, 1400.6, 1278.7; ESI-MS (m/z, %): 409.1 (M+H)+; 1H NMR (300MHz, DMSO-d6): δ 8.35 (d, 2H, J=8.3Hz), 7.84 (d, 2H, J=8.2Hz), 7.39 (d, 1H, J=8.6Hz), 7.06 (s, 1H), 6.88 (d, 1H, J=8.6Hz), 6.61 (s, 1H), 5.33 (s, 2H), 2.78 (d, 2H, J=6.9Hz), 2.56 (s, 3H), 2.15-2.04 (m, 1H), 1.11 (d, 3H, J=6.6Hz), 1.01.(d, 3H, J=6.7Hz).