Synthesis and in vitro anti-hepatitis B virus activity of 6H-[1]benzothiopyrano[4,3-b]quinolin-9-ols

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 13, 2009, Pages 4569-4574

  Jia, Wei ^a   Liu, Yajing ^a   Li, Wei ^a   Liu, Yan ^a   Zhang, Dajun ^a   Zhang, Peng ^a   Gong, Ping ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

6H 1 Benzothiopyrano 43 b quinolines; Anti HBV agents; Synthesis

Indexed keywords

10 METHOXY 2 METHYL 8 (MORPHOLINOMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 9 OL; 10 METHOXY 2,4 DIMETHYL 8 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 9 OL; 2 FLUORO 10 METHOXY 8 (PYRROLIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 9 OL; 8 [(DIETHYLAMINO)METHYL] 10 METHOXY 2 METHYL 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 9 OL; 8 [(DIETHYLAMINO)METHYL] 3 FLUORO 10 METHOXY 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 9 OL; QUINOLINOL DERIVATIVE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; DRUG CYTOTOXICITY; DRUG POTENCY; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL;

ANTIVIRAL AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; DNA, VIRAL; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; INHIBITORY CONCENTRATION 50; LIVER; MICROBIAL SENSITIVITY TESTS; QUINOLINES; STRUCTURE-ACTIVITY RELATIONSHIP;

HEPATITIS B VIRUS;

EID: 66449104212     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.05.001     Document Type: Article

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