Synthesis and in-vitro anti-hepatitis-B virus activity of 6H-[1]benzothiopyrano[4,3-b] quinolin-10-ols

Archiv der Pharmazie

Volumn 342, Issue 9, 2009, Pages 507-512

  Jia, Wei ^a   Zhao, Yanfang ^a   Li, Rongdong ^b   Wu, Yanjiao ^a   Li, Zebiao ^a   Gong, Ping ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b HUNAN UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

6H 1 benzothiopyrano 4,3 b quinolin 10 ols; Anti HBV activity; Synthesis

Indexed keywords

11 [(1H IMIDAZOL 1 YL)METHYL] 3 FLUORO 9 METHOXY 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 11 [(DIMETHYLAMINO)METHYL] 3 FLUORO 9 METHOXY 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 2 FLUORO 9 METHOXY 11 (MORPHOLINOMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 2 FLUORO 9 METHOXY 11 (MORPHOLINOMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL 5 OXIDE; 2 FLUORO 9 METHOXY 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 2 FLUORO 9 METHOXY 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL 5 OXIDE; 2,3,9 TRIMETHOXY 11 (MORPHOLINOMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 2,9 DIMETHOXY 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 3 FLUORO 9 METHOXY 11 (MORPHOLINOMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 3 FLUORO 9 METHOXY 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 3 FLUORO 9 METHOXY 11 (PYRROLIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 3 FLUORO 9 METHOXY 11 [(2 METHYL 1H IMIDAZOL 1 YL)METHYL] 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 9 METHOXY 2 METHYL 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 9 METHOXY 2,4 DIMETHYL 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 9 METHOXY 3 METHYL 11 (MORPHOLINOMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 9 METHOXY 3 METHYL 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 9 METHOXY 3 METHYL 11 (PIPERIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL 5 OXIDE; 9 METHOXY 3 METHYL 11 (PYRROLIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL; 9 METHOXY 3 METHYL 11 (PYRROLIDIN 1 YLMETHYL) 6H [1]BENZOTHIOPYRANO[4,3 B]QUINOLIN 10 OL 5 OXIDE; ANTIVIRUS AGENT; LAMIVUDINE; MANNICH BASE; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HEPATITIS B VIRUS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL;

ANTIVIRAL AGENTS; CELL LINE; CELL SURVIVAL; DNA, VIRAL; DRUG EVALUATION, PRECLINICAL; DRUG RESISTANCE, VIRAL; HEPATITIS B VIRUS; HYDROXYQUINOLINES; LAMIVUDINE; MOLECULAR STRUCTURE; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70149092748     PISSN: 03656233     EISSN: 15214184     Source Type: Journal    
DOI: 10.1002/ardp.200900070     Document Type: Article

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