메뉴 건너뛰기




Volumn 38, Issue 17, 2010, Pages 5784-5796

Multiple roles of the RNA polymerase β′ SW2 region in transcription initiation, promoter escape, and RNA elongation

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; DNA; NUCLEIC ACID; RNA; RNA POLYMERASE; RNA POLYMERASE BETA SUBUNIT; BETA' SUBUNIT OF RNA POLYMERASE; DNA DIRECTED RNA POLYMERASE; PRIMER DNA;

EID: 77957236078     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq355     Document Type: Article
Times cited : (25)

References (51)
  • 1
    • 0035827346 scopus 로고    scopus 로고
    • Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution
    • Cramer,P., Bushnell,D.A. and Kornberg,R.D. (2001) Structural basis of transcription: RNA polymerase II at 2.8 angstrom resolution. Science, 292, 1863-1876.
    • (2001) Science , vol.292 , pp. 1863-1876
    • Cramer, P.1    Bushnell, D.A.2    Kornberg, R.D.3
  • 2
    • 0035827332 scopus 로고    scopus 로고
    • Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution
    • Gnatt,A.L., Cramer,P., Fu,J., Bushnell,D.A. and Kornberg,R.D. (2001) Structural basis of transcription: an RNA polymerase II elongation complex at 3.3 A resolution. Science, 292, 1876-1882.
    • (2001) Science , vol.292 , pp. 1876-1882
    • Gnatt, A.L.1    Cramer, P.2    Fu, J.3    Bushnell, D.A.4    Kornberg, R.D.5
  • 6
    • 0033578701 scopus 로고    scopus 로고
    • Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution
    • Zhang,G., Campbell,E.A., Minakhin,L., Richter,C., Severinov,K. and Darst,S.A. (1999) Crystal structure of Thermus aquaticus core RNA polymerase at 3.3 A resolution. Cell, 98, 811-824.
    • (1999) Cell , vol.98 , pp. 811-824
    • Zhang, G.1    Campbell, E.A.2    Minakhin, L.3    Richter, C.4    Severinov, K.5    Darst, S.A.6
  • 7
    • 58149096676 scopus 로고    scopus 로고
    • Evidence for a tyrosine-adenine stacking interaction and for a short-lived open intermediate subsequent to initial binding of Escherichia coli RNA polymerase to promoter DNA
    • Schroeder,L.A., Gries,T.J., Saecker,R.M., Record,M.T. Jr, Harris,M.E. and DeHaseth,P.L. (2009) Evidence for a tyrosine-adenine stacking interaction and for a short-lived open intermediate subsequent to initial binding of Escherichia coli RNA polymerase to promoter DNA. J. Mol. Biol., 385, 339-349.
    • (2009) J. Mol. Biol. , vol.385 , pp. 339-349
    • Schroeder, L.A.1    Gries, T.J.2    Saecker, R.M.3    Record M.T., Jr.4    Harris, M.E.5    DeHaseth, P.L.6
  • 8
    • 34547640998 scopus 로고    scopus 로고
    • The -11A of promoter DNA and two conserved amino acids in the melting region of sigma70 both directly affect the rate limiting step in formation of the stable RNA polymerase-promoter complex, but they do not necessarily interact
    • Schroeder,L.A., Choi,A.J. and DeHaseth,P.L. (2007) The -11A of promoter DNA and two conserved amino acids in the melting region of sigma70 both directly affect the rate limiting step in formation of the stable RNA polymerase-promoter complex, but they do not necessarily interact. Nucleic Acids Res., 35, 4141-4153.
    • (2007) Nucleic Acids Res. , vol.35 , pp. 4141-4153
    • Schroeder, L.A.1    Choi, A.J.2    DeHaseth, P.L.3
  • 9
    • 0037073077 scopus 로고    scopus 로고
    • Promoter clearance and escape in prokaryotes
    • Hsu,L.M. (2002) Promoter clearance and escape in prokaryotes. Biochim. Biophys. Acta, 1577, 191-207.
    • (2002) Biochim. Biophys. Acta , vol.1577 , pp. 191-207
    • Hsu, L.M.1
  • 10
    • 66149123741 scopus 로고    scopus 로고
    • Direct detection of abortive RNA transcripts in vivo
    • Goldman,S.R., Ebright,R.H. and Nickels,B.E. (2009) Direct detection of abortive RNA transcripts in vivo. Science, 324, 927-928.
    • (2009) Science , vol.324 , pp. 927-928
    • Goldman, S.R.1    Ebright, R.H.2    Nickels, B.E.3
  • 11
    • 0037013332 scopus 로고    scopus 로고
    • Generality of the branched pathway in transcription initiation by Escherichia coli RNA polymerase
    • Susa,M., Sen,R. and Shimamoto,N. (2002) Generality of the branched pathway in transcription initiation by Escherichia coli RNA polymerase. J. Biol. Chem., 277, 15407-15412.
    • (2002) J. Biol. Chem. , vol.277 , pp. 15407-15412
    • Susa, M.1    Sen, R.2    Shimamoto, N.3
  • 12
    • 33745832269 scopus 로고    scopus 로고
    • Region 3.2 of the sigma subunit contributes to the binding of the 3′-initiating nucleotide in the RNA polymerase active center and facilitates promoter clearance during initiation
    • Kulbachinskiy,A. and Mustaev,A. (2006) Region 3.2 of the sigma subunit contributes to the binding of the 3′-initiating nucleotide in the RNA polymerase active center and facilitates promoter clearance during initiation. J. Biol. Chem., 281, 18273-18276.
    • (2006) J. Biol. Chem. , vol.281 , pp. 18273-18276
    • Kulbachinskiy, A.1    Mustaev, A.2
  • 13
    • 0037123659 scopus 로고    scopus 로고
    • Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution
    • Murakami,K.S., Masuda,S. and Darst,S.A. (2002) Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution. Science, 296, 1280-1284.
    • (2002) Science , vol.296 , pp. 1280-1284
    • Murakami, K.S.1    Masuda, S.2    Darst, S.A.3
  • 14
    • 15444366146 scopus 로고    scopus 로고
    • The interaction between sigma70 and the beta-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation
    • Nickels,B.E., Garrity,S.J., Mekler,V., Minakhin,L., Severinov,K., Ebright,R.H. and Hochschild,A. (2005) The interaction between sigma70 and the beta-flap of Escherichia coli RNA polymerase inhibits extension of nascent RNA during early elongation. Proc. Natl Acad. Sci. USA, 102, 4488-4493.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 4488-4493
    • Nickels, B.E.1    Garrity, S.J.2    Mekler, V.3    Minakhin, L.4    Severinov, K.5    Ebright, R.H.6    Hochschild, A.7
  • 16
    • 33746827367 scopus 로고    scopus 로고
    • The role of the largest RNA polymerase subunit lid element in preventing the formation of extended RNA-DNA hybrid
    • Naryshkina,T., Kuznedelov,K. and Severinov,K. (2006) The role of the largest RNA polymerase subunit lid element in preventing the formation of extended RNA-DNA hybrid. J. Mol. Biol., 361, 634-643.
    • (2006) J. Mol. Biol. , vol.361 , pp. 634-643
    • Naryshkina, T.1    Kuznedelov, K.2    Severinov, K.3
  • 17
    • 33746811857 scopus 로고    scopus 로고
    • The role of the lid element in transcription by E. coli RNA polymerase
    • Toulokhonov,I. and Landick,R. (2006) The role of the lid element in transcription by E. coli RNA polymerase. J. Mol. Biol., 361, 644-658.
    • (2006) J. Mol. Biol. , vol.361 , pp. 644-658
    • Toulokhonov, I.1    Landick, R.2
  • 18
    • 0032486142 scopus 로고    scopus 로고
    • RNA polymerase mutants that destabilize RNA polymerase-promoter complexes alter NTP-sensing by rrn P1 promoters
    • Bartlett,M.S., Gaal,T., Ross,W. and Gourse,R.L. (1998) RNA polymerase mutants that destabilize RNA polymerase-promoter complexes alter NTP-sensing by rrn P1 promoters. J. Mol. Biol., 279, 331-345.
    • (1998) J. Mol. Biol. , vol.279 , pp. 331-345
    • Bartlett, M.S.1    Gaal, T.2    Ross, W.3    Gourse, R.L.4
  • 19
    • 0347616927 scopus 로고    scopus 로고
    • Mutations in β′ subunit of the Escherichia coli RNA polymerase influence interaction with the downstream DNA duplex in the elongation complex
    • Kulbachinskiy,A.V., Ershova,G.V., Korzheva,N.V., Brodolin,K.L. and Nikiforov,V.G. (2002) Mutations in β′ subunit of the Escherichia coli RNA polymerase influence interaction with the downstream DNA duplex in the elongation complex. Genetika, 38, 1207-1211.
    • (2002) Genetika , vol.38 , pp. 1207-1211
    • Kulbachinskiy, A.V.1    Ershova, G.V.2    Korzheva, N.V.3    Brodolin, K.L.4    Nikiforov, V.G.5
  • 20
    • 0031456021 scopus 로고    scopus 로고
    • A mutant RNA polymerase that forms unusual open promoter complexes
    • Severinov,K. and Darst,S.A. (1997) A mutant RNA polymerase that forms unusual open promoter complexes. Proc. Natl Acad. Sci. USA, 94, 13481-13486.
    • (1997) Proc. Natl Acad. Sci. USA , vol.94 , pp. 13481-13486
    • Severinov, K.1    Darst, S.A.2
  • 21
    • 0034682813 scopus 로고    scopus 로고
    • Dissection of two hallmarks of the open promoter complex by mutation in an RNA polymerase core subunit
    • Nechaev,S., Chlenov,M. and Severinov,K. (2000) Dissection of two hallmarks of the open promoter complex by mutation in an RNA polymerase core subunit. J. Biol. Chem., 275, 25516-25522.
    • (2000) J. Biol. Chem. , vol.275 , pp. 25516-25522
    • Nechaev, S.1    Chlenov, M.2    Severinov, K.3
  • 22
    • 0037020252 scopus 로고    scopus 로고
    • The downstream DNA jaw of bacterial RNA polymerase facilitates both transcriptional initiation and pausing
    • Ederth,J., Artsimovitch,I., Isaksson,L.A. and Landick,R. (2002) The downstream DNA jaw of bacterial RNA polymerase facilitates both transcriptional initiation and pausing. J. Biol. Chem., 277, 37456-37463.
    • (2002) J. Biol. Chem. , vol.277 , pp. 37456-37463
    • Ederth, J.1    Artsimovitch, I.2    Isaksson, L.A.3    Landick, R.4
  • 23
    • 10944232674 scopus 로고    scopus 로고
    • Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS
    • Kettenberger,H., Armache,K.J. and Cramer,P. (2004) Complete RNA polymerase II elongation complex structure and its interactions with NTP and TFIIS. Mol. Cell, 16, 955-965.
    • (2004) Mol. Cell , vol.16 , pp. 955-965
    • Kettenberger, H.1    Armache, K.J.2    Cramer, P.3
  • 24
    • 33751235874 scopus 로고    scopus 로고
    • Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis
    • Wang,D., Bushnell,D.A., Westover,K.D., Kaplan,C.D. and Kornberg,R.D. (2006) Structural basis of transcription: role of the trigger loop in substrate specificity and catalysis. Cell, 127, 941-954.
    • (2006) Cell , vol.127 , pp. 941-954
    • Wang, D.1    Bushnell, D.A.2    Westover, K.D.3    Kaplan, C.D.4    Kornberg, R.D.5
  • 25
    • 49449102926 scopus 로고    scopus 로고
    • Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocation
    • Brueckner,F. and Cramer,P. (2008) Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocation. Nat. Struct. Mol. Biol., 15, 811-818.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 811-818
    • Brueckner, F.1    Cramer, P.2
  • 26
    • 58849139777 scopus 로고    scopus 로고
    • Allosteric control of Escherichia coli rRNA promoter complexes by DksA
    • Rutherford,S.T., Villers,C.L., Lee,J.H., Ross,W. and Gourse,R.L. (2009) Allosteric control of Escherichia coli rRNA promoter complexes by DksA. Genes Dev., 23, 236-248.
    • (2009) Genes Dev. , vol.23 , pp. 236-248
    • Rutherford, S.T.1    Villers, C.L.2    Lee, J.H.3    Ross, W.4    Gourse, R.L.5
  • 28
    • 27144526242 scopus 로고    scopus 로고
    • A functional role for the switch 2 region of yeast RNA polymerase II in transcription start site utilization and abortive initiation
    • Majovski,R.C., Khaperskyy,D.A., Ghazy,M.A. and Ponticelli,A.S. (2005) A functional role for the switch 2 region of yeast RNA polymerase II in transcription start site utilization and abortive initiation. J. Biol. Chem., 280, 34917-34923.
    • (2005) J. Biol. Chem. , vol.280 , pp. 34917-34923
    • Majovski, R.C.1    Khaperskyy, D.A.2    Ghazy, M.A.3    Ponticelli, A.S.4
  • 29
    • 39149093390 scopus 로고    scopus 로고
    • Structure-function analysis of the RNA polymerase cleft loops elucidates initial transcription, DNA unwinding and RNA displacement
    • Naji,S., Bertero,M.G., Spitalny,P., Cramer,P. and Thomm,M. (2008) Structure-function analysis of the RNA polymerase cleft loops elucidates initial transcription, DNA unwinding and RNA displacement. Nucleic Acids Res., 36, 676-687.
    • (2008) Nucleic Acids Res , vol.36 , pp. 676-687
    • Naji, S.1    Bertero, M.G.2    Spitalny, P.3    Cramer, P.4    Thomm, M.5
  • 31
    • 73649138940 scopus 로고    scopus 로고
    • Molecular evolution of multisubunit RNA polymerases: sequence analysis
    • Lane,W.J. and Darst,S.A. (2010) Molecular evolution of multisubunit RNA polymerases: sequence analysis. J. Mol. Biol., 395, 671-685.
    • (2010) J. Mol. Biol. , vol.395 , pp. 671-685
    • Lane, W.J.1    Darst, S.A.2
  • 33
    • 4644265121 scopus 로고    scopus 로고
    • Discrimination against deoxyribonucleotide substrates by bacterial RNA polymerase
    • Svetlov,V., Vassylyev,D.G. and Artsimovitch,I. (2004) Discrimination against deoxyribonucleotide substrates by bacterial RNA polymerase. J. Biol. Chem., 279, 38087-38090.
    • (2004) J. Biol. Chem. , vol.279 , pp. 38087-38090
    • Svetlov, V.1    Vassylyev, D.G.2    Artsimovitch, I.3
  • 34
    • 0028104343 scopus 로고
    • Termination-altering amino acid substitutions in the beta' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation
    • Weilbaecher,R., Hebron,C., Feng,G. and Landick,R. (1994) Termination-altering amino acid substitutions in the beta' subunit of Escherichia coli RNA polymerase identify regions involved in RNA chain elongation. Genes Dev., 8, 2913-2927.
    • (1994) Genes Dev. , vol.8 , pp. 2913-2927
    • Weilbaecher, R.1    Hebron, C.2    Feng, G.3    Landick, R.4
  • 35
    • 57349147214 scopus 로고    scopus 로고
    • Monitoring abortive initiation
    • Hsu,L.M. (2009) Monitoring abortive initiation. Methods, 47, 25-36.
    • (2009) Methods , vol.47 , pp. 25-36
    • Hsu, L.M.1
  • 36
    • 0032113494 scopus 로고    scopus 로고
    • Crucial role of the RNA:DNA hybrid in the processivity of transcription
    • Sidorenkov,I., Komissarova,N. and Kashlev,M. (1998) Crucial role of the RNA:DNA hybrid in the processivity of transcription. Mol. Cell, 2, 55-64.
    • (1998) Mol. Cell , vol.2 , pp. 55-64
    • Sidorenkov, I.1    Komissarova, N.2    Kashlev, M.3
  • 37
    • 0036304755 scopus 로고    scopus 로고
    • Kinetic studies and structural models of the association of E. coli sigma(70) RNA polymerase with the lambdaP(R) promoter: large scale conformational changes in forming the kinetically significant intermediates
    • Saecker,R.M., Tsodikov,O.V., McQuade,K.L., Schlax,P.E. Jr, Capp,M.W. and Record,M.T. Jr. (2002) Kinetic studies and structural models of the association of E. coli sigma(70) RNA polymerase with the lambdaP(R) promoter: large scale conformational changes in forming the kinetically significant intermediates. J. Mol. Biol., 319, 649-671.
    • (2002) J. Mol. Biol. , vol.319 , pp. 649-671
    • Saecker, R.M.1    Tsodikov, O.V.2    McQuade, K.L.3    Schlax P.E., Jr.4    Capp, M.W.5    Record M.T., Jr.6
  • 38
    • 39049123619 scopus 로고    scopus 로고
    • Late steps in the formation of E. coli RNA polymerase-lambda PR promoter open complexes: characterization of conformational changes by rapid [perturbant] upshift experiments
    • Kontur,W.S., Saecker,R.M., Capp,M.W. and Record,M.T. Jr (2008) Late steps in the formation of E. coli RNA polymerase-lambda PR promoter open complexes: characterization of conformational changes by rapid [perturbant] upshift experiments. J. Mol. Biol., 376, 1034-1047.
    • (2008) J. Mol. Biol. , vol.376 , pp. 1034-1047
    • Kontur, W.S.1    Saecker, R.M.2    Capp, M.W.3    Record M.T. Jr4
  • 39
    • 0035918272 scopus 로고    scopus 로고
    • The beta' subunit of Escherichia coli RNA polymerase is not required for interaction with initiating nucleotide but is necessary for interaction with rifampicin
    • Naryshkina,T., Mustaev,A., Darst,S.A. and Severinov,K. (2001) The beta' subunit of Escherichia coli RNA polymerase is not required for interaction with initiating nucleotide but is necessary for interaction with rifampicin. J. Biol. Chem., 276, 13308-13313.
    • (2001) J. Biol. Chem. , vol.276 , pp. 13308-13313
    • Naryshkina, T.1    Mustaev, A.2    Darst, S.A.3    Severinov, K.4
  • 40
    • 1142274214 scopus 로고    scopus 로고
    • Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms
    • Bushnell,D.A., Westover,K.D., Davis,R.E. and Kornberg,R.D. (2004) Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms. Science, 303, 983-988.
    • (2004) Science , vol.303 , pp. 983-988
    • Bushnell, D.A.1    Westover, K.D.2    Davis, R.E.3    Kornberg, R.D.4
  • 42
    • 74249102477 scopus 로고    scopus 로고
    • Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism
    • Liu,X., Bushnell,D.A., Wang,D., Calero,G. and Kornberg,R.D. (2010) Structure of an RNA polymerase II-TFIIB complex and the transcription initiation mechanism. Science, 327, 206-2
    • (2010) Science , vol.327 , pp. 206-212
    • Liu, X.1    Bushnell, D.A.2    Wang, D.3    Calero, G.4    Kornberg, R.D.5
  • 43
    • 34648825451 scopus 로고    scopus 로고
    • TFIIB and the regulation of transcription by RNA polymerase II
    • Deng,W. and Roberts,S.G. (2007) TFIIB and the regulation of transcription by RNA polymerase II. Chromosoma, 116, 417-429.
    • (2007) Chromosoma , vol.116 , pp. 417-429
    • Deng, W.1    Roberts, S.G.2
  • 44
    • 47049101233 scopus 로고    scopus 로고
    • Control of the timing of promoter escape and RNA catalysis by the transcription factor IIb fingertip
    • Tran,K. and Gralla,J.D. (2008) Control of the timing of promoter escape and RNA catalysis by the transcription factor IIb fingertip. J. Biol. Chem., 283, 15665-15671.
    • (2008) J. Biol. Chem. , vol.283 , pp. 15665-15671
    • Tran, K.1    Gralla, J.D.2
  • 45
    • 77949490923 scopus 로고    scopus 로고
    • Phosphorylation of TFIIB links transcription initiation and termination
    • Wang,Y., Fairley,J.A. and Roberts,S.G. (2010) Phosphorylation of TFIIB links transcription initiation and termination. Curr. Biol., 20, 548-553.
    • (2010) Curr. Biol. , vol.20 , pp. 548-553
    • Wang, Y.1    Fairley, J.A.2    Roberts, S.G.3
  • 46
    • 33751212468 scopus 로고    scopus 로고
    • Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism
    • Kapanidis,A.N., Margeat,E., Ho,S.O., Kortkhonjia,E., Weiss,S. and Ebright,R.H. (2006) Initial transcription by RNA polymerase proceeds through a DNA-scrunching mechanism. Science, 314, 1144-1147.
    • (2006) Science , vol.314 , pp. 1144-1147
    • Kapanidis, A.N.1    Margeat, E.2    Ho, S.O.3    Kortkhonjia, E.4    Weiss, S.5    Ebright, R.H.6
  • 47
    • 33751218319 scopus 로고    scopus 로고
    • Abortive initiation and productive initiation by RNA polymerase involve DNA scrunching
    • Revyakin,A., Liu,C., Ebright,R.H. and Strick,T.R. (2006) Abortive initiation and productive initiation by RNA polymerase involve DNA scrunching. Science, 314, 1139-1143.
    • (2006) Science , vol.314 , pp. 1139-1143
    • Revyakin, A.1    Liu, C.2    Ebright, R.H.3    Strick, T.R.4
  • 48
    • 0029818631 scopus 로고    scopus 로고
    • Transcription processivity: protein-DNA interactions holding together the elongation complex
    • Nudler,E., Avetissova,E., Markovtsov,V. and Goldfarb,A. (1996) Transcription processivity: protein-DNA interactions holding together the elongation complex. Science, 273, 211-217.
    • (1996) Science , vol.273 , pp. 211-217
    • Nudler, E.1    Avetissova, E.2    Markovtsov, V.3    Goldfarb, A.4
  • 49
    • 0034051171 scopus 로고    scopus 로고
    • The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex
    • Kireeva,M.L., Komissarova,N., Waugh,D.S. and Kashlev,M. (2000) The 8-nucleotide-long RNA:DNA hybrid is a primary stability determinant of the RNA polymerase II elongation complex. J. Biol. Chem., 275, 6530-6536.
    • (2000) J. Biol. Chem. , vol.275 , pp. 6530-6536
    • Kireeva, M.L.1    Komissarova, N.2    Waugh, D.S.3    Kashlev, M.4
  • 50
    • 0037086450 scopus 로고    scopus 로고
    • Structure-based analysis of RNA polymerase function: the largest subunit's rudder contributes critically to elongation complex stability and is not involved in the maintenance of RNA-DNA hybrid length
    • Kuznedelov,K., Korzheva,N., Mustaev,A. and Severinov,K. (2002) Structure-based analysis of RNA polymerase function: the largest subunit's rudder contributes critically to elongation complex stability and is not involved in the maintenance of RNA-DNA hybrid length. EMBO J., 21, 1369-1378.
    • (2002) EMBO J. , vol.21 , pp. 1369-1378
    • Kuznedelov, K.1    Korzheva, N.2    Mustaev, A.3    Severinov, K.4
  • 51
    • 70350619725 scopus 로고    scopus 로고
    • Frequency and characterisation of spontaneous lipiarmycin-resistant Enterococcus faecalis mutants selected in vitro
    • Gualtieri,M., Tupin,A., Brodolin,K. and Leonetti,J.P. (2009) Frequency and characterisation of spontaneous lipiarmycin-resistant Enterococcus faecalis mutants selected in vitro. Int. J. Antimicrob. Agents, 34, 605-606.
    • (2009) Int. J. Antimicrob. Agents , vol.34 , pp. 605-606
    • Gualtieri, M.1    Tupin, A.2    Brodolin, K.3    Leonetti, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.