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Volumn 73, Issue 11, 2010, Pages 2267-2276

Pathogen proteomes during infection: A basis for infection research and novel control strategies

Author keywords

Bacterial infection; Pathogen metabolism; Vaccine antigen identification

Indexed keywords

ANTIINFECTIVE AGENT; BACTERIAL ANTIGEN; BACTERIAL PROTEIN;

EID: 77957234670     PISSN: 18743919     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jprot.2010.08.004     Document Type: Review
Times cited : (36)

References (67)
  • 1
    • 12944302098 scopus 로고    scopus 로고
    • Lack of development of new antimicrobial drugs: a potential serious threat to public health
    • Norrby S.R., Nord C.E., Finch R. Lack of development of new antimicrobial drugs: a potential serious threat to public health. Lancet Infect Dis 2005, 5:115-119.
    • (2005) Lancet Infect Dis , vol.5 , pp. 115-119
    • Norrby, S.R.1    Nord, C.E.2    Finch, R.3
  • 2
    • 39049128343 scopus 로고    scopus 로고
    • Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern
    • Pitout J.D., Laupland K.B. Extended-spectrum beta-lactamase-producing Enterobacteriaceae: an emerging public-health concern. Lancet Infect Dis 2008, 8:159-166.
    • (2008) Lancet Infect Dis , vol.8 , pp. 159-166
    • Pitout, J.D.1    Laupland, K.B.2
  • 4
    • 77956652030 scopus 로고    scopus 로고
    • Resistance or decreased susceptibility to glycopeptides, daptomycin, and linezolid in methicillin-resistant Staphylococcus aureus
    • Nannini E., Murray B.E., Arias C.A. Resistance or decreased susceptibility to glycopeptides, daptomycin, and linezolid in methicillin-resistant Staphylococcus aureus. Curr Opin Pharmacol 2010, 30.
    • (2010) Curr Opin Pharmacol , vol.30
    • Nannini, E.1    Murray, B.E.2    Arias, C.A.3
  • 5
    • 57749107808 scopus 로고    scopus 로고
    • Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America
    • Boucher H.W., et al. Bad bugs, no drugs: no ESKAPE! An update from the Infectious Diseases Society of America. Clin Infect Dis 2009, 48:1-12.
    • (2009) Clin Infect Dis , vol.48 , pp. 1-12
    • Boucher, H.W.1
  • 6
    • 0036259796 scopus 로고    scopus 로고
    • Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells
    • Molestina R.E., Klein J.B., Miller R.D., Pierce W.H., Ramirez J.A., Summersgill J.T. Proteomic analysis of differentially expressed Chlamydia pneumoniae genes during persistent infection of HEp-2 cells. Infect Immun 2002, 70:2976-2981.
    • (2002) Infect Immun , vol.70 , pp. 2976-2981
    • Molestina, R.E.1    Klein, J.B.2    Miller, R.D.3    Pierce, W.H.4    Ramirez, J.A.5    Summersgill, J.T.6
  • 7
    • 33646266241 scopus 로고    scopus 로고
    • Proteins unique to intraphagosomally grown Mycobacterium tuberculosis
    • Mattow J., et al. Proteins unique to intraphagosomally grown Mycobacterium tuberculosis. Proteomics 2006, 6:2485-2494.
    • (2006) Proteomics , vol.6 , pp. 2485-2494
    • Mattow, J.1
  • 8
    • 33749424678 scopus 로고    scopus 로고
    • Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages
    • Shi L., et al. Proteomic analysis of Salmonella enterica serovar typhimurium isolated from RAW 264.7 macrophages: identification of a novel protein that contributes to the replication of serovar typhimurium inside macrophages. J Biol Chem 2006, 281:29131-29140.
    • (2006) J Biol Chem , vol.281 , pp. 29131-29140
    • Shi, L.1
  • 9
    • 37049009528 scopus 로고    scopus 로고
    • Quantitative proteomics of intracellular Porphyromonas gingivalis
    • Xia Q., Wang T., Taub F., Park Y., Capestany C.A., Lamont R.J., et al. Quantitative proteomics of intracellular Porphyromonas gingivalis. Proteomics 2007, 7:4323-4337.
    • (2007) Proteomics , vol.7 , pp. 4323-4337
    • Xia, Q.1    Wang, T.2    Taub, F.3    Park, Y.4    Capestany, C.A.5    Lamont, R.J.6
  • 10
    • 77955119702 scopus 로고    scopus 로고
    • Time-resolved quantitative proteome profiling of host-pathogen interactions: the response of Staphylococcus aureus RN1HG to internalisation by human airway epithelial cells. Proteomics
    • Schmidt, F. et al. Time-resolved quantitative proteome profiling of host-pathogen interactions: the response of Staphylococcus aureus RN1HG to internalisation by human airway epithelial cells. Proteomics 10, 2801-11.
    • , vol.10 , pp. 2801-11
    • Schmidt, F.1
  • 11
    • 0037015610 scopus 로고    scopus 로고
    • Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry
    • Lasonder E., et al. Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry. Nature 2002, 419:537-542.
    • (2002) Nature , vol.419 , pp. 537-542
    • Lasonder, E.1
  • 12
    • 0037015602 scopus 로고    scopus 로고
    • A proteomic view of the Plasmodium falciparum life cycle
    • Florens L., et al. A proteomic view of the Plasmodium falciparum life cycle. Nature 2002, 419:520-526.
    • (2002) Nature , vol.419 , pp. 520-526
    • Florens, L.1
  • 13
    • 19944429644 scopus 로고    scopus 로고
    • A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses
    • Hall N., et al. A comprehensive survey of the Plasmodium life cycle by genomic, transcriptomic, and proteomic analyses. Science 2005, 307:82-86.
    • (2005) Science , vol.307 , pp. 82-86
    • Hall, N.1
  • 14
    • 20444405371 scopus 로고    scopus 로고
    • Proteome analysis of separated male and female gametocytes reveals novel sex-specific Plasmodium biology
    • Khan S.M., Franke-Fayard B., Mair G.R., Lasonder E., Janse C.J., Mann M., et al. Proteome analysis of separated male and female gametocytes reveals novel sex-specific Plasmodium biology. Cell 2005, 121:675-687.
    • (2005) Cell , vol.121 , pp. 675-687
    • Khan, S.M.1    Franke-Fayard, B.2    Mair, G.R.3    Lasonder, E.4    Janse, C.J.5    Mann, M.6
  • 15
    • 55449113575 scopus 로고    scopus 로고
    • Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity
    • Lasonder E., et al. Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity. PLoS Pathog 2008, 4:e1000195.
    • (2008) PLoS Pathog , vol.4
    • Lasonder, E.1
  • 16
    • 52649088373 scopus 로고    scopus 로고
    • Transgenic, fluorescent Leishmania mexicana allow direct analysis of the proteome of intracellular amastigotes
    • Paape D., et al. Transgenic, fluorescent Leishmania mexicana allow direct analysis of the proteome of intracellular amastigotes. Mol Cell Proteomics 2008, 7:1688-1701.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 1688-1701
    • Paape, D.1
  • 18
    • 27644555055 scopus 로고    scopus 로고
    • Interpretation of shotgun proteomic data: the protein inference problem
    • Nesvizhskii A.I., Aebersold R. Interpretation of shotgun proteomic data: the protein inference problem. Mol Cell Proteomics 2005, 4:1419-1440.
    • (2005) Mol Cell Proteomics , vol.4 , pp. 1419-1440
    • Nesvizhskii, A.I.1    Aebersold, R.2
  • 19
    • 77957220211 scopus 로고    scopus 로고
    • Two-dimensional gel electrophoresis in proteomics: past, present and future
    • Rabilloud, T. (2010). Two-dimensional gel electrophoresis in proteomics: past, present and future. 73 (11): 2064-2077.
    • (2010) , vol.73 , Issue.11 , pp. 2064-2077
    • Rabilloud, T.1
  • 20
    • 0034662907 scopus 로고    scopus 로고
    • Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology
    • Gygi S.P., Corthals G.L., Zhang Y., Rochon Y., Aebersold R. Evaluation of two-dimensional gel electrophoresis-based proteome analysis technology. Proc Natl Acad Sci USA 2000, 97:9390-9395.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 9390-9395
    • Gygi, S.P.1    Corthals, G.L.2    Zhang, Y.3    Rochon, Y.4    Aebersold, R.5
  • 21
    • 0042328144 scopus 로고    scopus 로고
    • Dynamics of bacterial growth and distribution within the liver during Salmonella infection
    • Sheppard M., Webb C., Heath F., Mallows V., Emilianus R., Maskell D., et al. Dynamics of bacterial growth and distribution within the liver during Salmonella infection. Cell Microbiol 2003, 5:593-600.
    • (2003) Cell Microbiol , vol.5 , pp. 593-600
    • Sheppard, M.1    Webb, C.2    Heath, F.3    Mallows, V.4    Emilianus, R.5    Maskell, D.6
  • 22
    • 32944469752 scopus 로고    scopus 로고
    • Analysis of the Pasteurella multocida outer membrane sub-proteome and its response to the in vivo environment of the natural host
    • Boyce J.D., Cullen P.A., Nguyen V., Wilkie I., Adler B. Analysis of the Pasteurella multocida outer membrane sub-proteome and its response to the in vivo environment of the natural host. Proteomics 2006, 6:870-880.
    • (2006) Proteomics , vol.6 , pp. 870-880
    • Boyce, J.D.1    Cullen, P.A.2    Nguyen, V.3    Wilkie, I.4    Adler, B.5
  • 23
    • 33744548258 scopus 로고    scopus 로고
    • In vivo proteomic analysis of the intracellular bacterial pathogen, Francisella tularensis, isolated from mouse spleen
    • Twine S.M., Mykytczuk N.C., Petit M.D., Shen H., Sjostedt A., Wayne Conlan J., et al. In vivo proteomic analysis of the intracellular bacterial pathogen, Francisella tularensis, isolated from mouse spleen. Biochem Biophys Res Commun 2006, 345:1621-1633.
    • (2006) Biochem Biophys Res Commun , vol.345 , pp. 1621-1633
    • Twine, S.M.1    Mykytczuk, N.C.2    Petit, M.D.3    Shen, H.4    Sjostedt, A.5    Wayne Conlan, J.6
  • 24
    • 33645030241 scopus 로고    scopus 로고
    • Robust Salmonella metabolism limits possibilities for new antimicrobials
    • Becker D., Selbach M., Rollenhagen C., Ballmaier M., Meyer T.F., Mann M., et al. Robust Salmonella metabolism limits possibilities for new antimicrobials. Nature 2006, 440:303-307.
    • (2006) Nature , vol.440 , pp. 303-307
    • Becker, D.1    Selbach, M.2    Rollenhagen, C.3    Ballmaier, M.4    Meyer, T.F.5    Mann, M.6
  • 25
    • 38349159563 scopus 로고    scopus 로고
    • A combined transcriptome and proteome survey of malaria parasite liver stages
    • Tarun A.S., et al. A combined transcriptome and proteome survey of malaria parasite liver stages. Proc Natl Acad Sci USA 2008, 105:305-310.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 305-310
    • Tarun, A.S.1
  • 26
    • 0037134794 scopus 로고    scopus 로고
    • Optimization of GFP levels for analyzing Salmonella gene expression during an infection
    • Wendland M., Bumann D. Optimization of GFP levels for analyzing Salmonella gene expression during an infection. FEBS Lett 2002, 521:105-108.
    • (2002) FEBS Lett , vol.521 , pp. 105-108
    • Wendland, M.1    Bumann, D.2
  • 27
    • 0036229497 scopus 로고    scopus 로고
    • Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometry
    • Bumann D. Examination of Salmonella gene expression in an infected mammalian host using the green fluorescent protein and two-colour flow cytometry. Mol Microbiol 2002, 43:1269-1283.
    • (2002) Mol Microbiol , vol.43 , pp. 1269-1283
    • Bumann, D.1
  • 28
    • 77149120797 scopus 로고    scopus 로고
    • Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux
    • Wang Q., et al. Acetylation of metabolic enzymes coordinates carbon source utilization and metabolic flux. Science 2010, 327:1004-1007.
    • (2010) Science , vol.327 , pp. 1004-1007
    • Wang, Q.1
  • 29
    • 39749166860 scopus 로고    scopus 로고
    • Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation
    • Macek B., Gnad F., Soufi B., Kumar C., Olsen J.V., Mijakovic I., et al. Phosphoproteome analysis of E. coli reveals evolutionary conservation of bacterial Ser/Thr/Tyr phosphorylation. Mol Cell Proteomics 2008, 7:299-307.
    • (2008) Mol Cell Proteomics , vol.7 , pp. 299-307
    • Macek, B.1    Gnad, F.2    Soufi, B.3    Kumar, C.4    Olsen, J.V.5    Mijakovic, I.6
  • 30
    • 33644763936 scopus 로고    scopus 로고
    • Salmonella enterica highly expressed genes are disease specific
    • Rollenhagen C., Bumann D. Salmonella enterica highly expressed genes are disease specific. Infect Immun 2006, 74:1649-1660.
    • (2006) Infect Immun , vol.74 , pp. 1649-1660
    • Rollenhagen, C.1    Bumann, D.2
  • 31
    • 68449102172 scopus 로고    scopus 로고
    • Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans
    • Malmstrom J., Beck M., Schmidt A., Lange V., Deutsch E.W., Aebersold R. Proteome-wide cellular protein concentrations of the human pathogen Leptospira interrogans. Nature 2009, 460:762-765.
    • (2009) Nature , vol.460 , pp. 762-765
    • Malmstrom, J.1    Beck, M.2    Schmidt, A.3    Lange, V.4    Deutsch, E.W.5    Aebersold, R.6
  • 32
    • 33845311869 scopus 로고    scopus 로고
    • Signature-tagged mutagenesis: barcoding mutants for genome-wide screens
    • Mazurkiewicz P., Tang C.M., Boone C., Holden D.W. Signature-tagged mutagenesis: barcoding mutants for genome-wide screens. Nat Rev Genet 2006, 7:929-939.
    • (2006) Nat Rev Genet , vol.7 , pp. 929-939
    • Mazurkiewicz, P.1    Tang, C.M.2    Boone, C.3    Holden, D.W.4
  • 34
    • 77749282898 scopus 로고    scopus 로고
    • The global burden of nontyphoidal Salmonella gastroenteritis. Clin Infect Dis 50
    • Majowicz, S.E. et al. The global burden of nontyphoidal Salmonella gastroenteritis. Clin Infect Dis 50, 882-9.
    • Majowicz, S.E.1
  • 35
    • 23944494081 scopus 로고    scopus 로고
    • Typhoid and paratyphoid fever
    • Bhan M.K., Bahl R., Bhatnagar S. Typhoid and paratyphoid fever. Lancet 2005, 366:749-762.
    • (2005) Lancet , vol.366 , pp. 749-762
    • Bhan, M.K.1    Bahl, R.2    Bhatnagar, S.3
  • 36
    • 33947362035 scopus 로고    scopus 로고
    • Antimicrobial resistance in nontyphoidal Salmonella
    • Alcaine S.D., Warnick L.D., Wiedmann M. Antimicrobial resistance in nontyphoidal Salmonella. J Food Prot 2007, 70:780-790.
    • (2007) J Food Prot , vol.70 , pp. 780-790
    • Alcaine, S.D.1    Warnick, L.D.2    Wiedmann, M.3
  • 37
    • 77952897822 scopus 로고    scopus 로고
    • Typhoid in Kenya is associated with a dominant multidrug-resistant Salmonella enterica serovar Typhi haplotype that is also widespread in Southeast Asia. J Clin Microbiol 48
    • Kariuki, S. et al. Typhoid in Kenya is associated with a dominant multidrug-resistant Salmonella enterica serovar Typhi haplotype that is also widespread in Southeast Asia. J Clin Microbiol 48, 2171-6.
    • Kariuki, S.1
  • 38
    • 33749527729 scopus 로고    scopus 로고
    • Multidrug-resistant Salmonella enterica serovar typhi isolates with high-level resistance to ciprofloxacin in Dhaka, Bangladesh
    • Ahmed D., D'Costa L.T., Alam K., Nair G.B., Hossain M.A. Multidrug-resistant Salmonella enterica serovar typhi isolates with high-level resistance to ciprofloxacin in Dhaka, Bangladesh. Antimicrob Agents Chemother 2006, 50:3516-3517.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 3516-3517
    • Ahmed, D.1    D'Costa, L.T.2    Alam, K.3    Nair, G.B.4    Hossain, M.A.5
  • 39
    • 69349099557 scopus 로고    scopus 로고
    • Analysis of pools of targeted Salmonella deletion mutants identifies novel genes affecting fitness during competitive infection in mice
    • Santiviago C.A., Reynolds M.M., Porwollik S., Choi S.H., Long F., Andrews-Polymenis H.L., et al. Analysis of pools of targeted Salmonella deletion mutants identifies novel genes affecting fitness during competitive infection in mice. PLoS Pathog 2009, 5:e1000477.
    • (2009) PLoS Pathog , vol.5
    • Santiviago, C.A.1    Reynolds, M.M.2    Porwollik, S.3    Choi, S.H.4    Long, F.5    Andrews-Polymenis, H.L.6
  • 40
    • 70049087126 scopus 로고    scopus 로고
    • Comprehensive identification of Salmonella enterica serovar typhimurium genes required for infection of BALB/c mice
    • Chaudhuri R.R., et al. Comprehensive identification of Salmonella enterica serovar typhimurium genes required for infection of BALB/c mice. PLoS Pathog 2009, 5:e1000529.
    • (2009) PLoS Pathog , vol.5
    • Chaudhuri, R.R.1
  • 41
    • 0037133671 scopus 로고    scopus 로고
    • Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis
    • Akashi H., Gojobori T. Metabolic efficiency and amino acid composition in the proteomes of Escherichia coli and Bacillus subtilis. Proc Natl Acad Sci USA 2002, 99:3695-3700.
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 3695-3700
    • Akashi, H.1    Gojobori, T.2
  • 42
    • 0031869632 scopus 로고    scopus 로고
    • At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice
    • Bowe F., Lipps C.J., Tsolis R.M., Groisman E., Heffron F., Kusters J.G. At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice. Infect Immun 1998, 66:3372-3377.
    • (1998) Infect Immun , vol.66 , pp. 3372-3377
    • Bowe, F.1    Lipps, C.J.2    Tsolis, R.M.3    Groisman, E.4    Heffron, F.5    Kusters, J.G.6
  • 43
    • 36348937934 scopus 로고    scopus 로고
    • FACS-isolation of Salmonella-infected cells with defined bacterial load from mouse spleen
    • epub ahead of print Sep 11
    • Thöne F., Schwanhäuser B., Becker D., Ballmaier M., Bumann D. FACS-isolation of Salmonella-infected cells with defined bacterial load from mouse spleen. J Microbiol Meth 2007, epub ahead of print Sep 11.
    • (2007) J Microbiol Meth
    • Thöne, F.1    Schwanhäuser, B.2    Becker, D.3    Ballmaier, M.4    Bumann, D.5
  • 44
    • 77957242540 scopus 로고    scopus 로고
    • It's the machine that matters: predicting gene function and phenotype from protein networks
    • Wang, P.I. and Marcotte, E.M. (2010). It's the machine that matters: predicting gene function and phenotype from protein networks. 73 (11): 2277-2289.
    • (2010) , vol.73 , Issue.11 , pp. 2277-2289
    • Wang, P.I.1    Marcotte, E.M.2
  • 45
    • 58149179979 scopus 로고    scopus 로고
    • EcoCyc: a comprehensive view of Escherichia coli biology
    • Keseler I.M., et al. EcoCyc: a comprehensive view of Escherichia coli biology. Nucleic Acids Res 2009, 37:D464-D470.
    • (2009) Nucleic Acids Res , vol.37
    • Keseler, I.M.1
  • 46
    • 38549126643 scopus 로고    scopus 로고
    • KEGG for linking genomes to life and the environment
    • Kanehisa M., et al. KEGG for linking genomes to life and the environment. Nucleic Acids Res 2008, 36:D480-D484.
    • (2008) Nucleic Acids Res , vol.36
    • Kanehisa, M.1
  • 47
    • 70349751621 scopus 로고    scopus 로고
    • System-level analysis of Salmonella metabolism during infection
    • Bumann D. System-level analysis of Salmonella metabolism during infection. Curr Opin Microbiol 2009, 12:559-567.
    • (2009) Curr Opin Microbiol , vol.12 , pp. 559-567
    • Bumann, D.1
  • 48
    • 61949263942 scopus 로고    scopus 로고
    • Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens
    • Brinster S., Lamberet G., Staels B., Trieu-Cuot P., Gruss A., Poyart C. Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens. Nature 2009, 458:83-86.
    • (2009) Nature , vol.458 , pp. 83-86
    • Brinster, S.1    Lamberet, G.2    Staels, B.3    Trieu-Cuot, P.4    Gruss, A.5    Poyart, C.6
  • 50
    • 77957233793 scopus 로고    scopus 로고
    • Trieu-Cuot, P., Gruss, A. and Poyart, C. Brinster et al. reply. Nature 463, E4-E4
    • Brinster, S., Lamberet, G., Staels, B., Trieu-Cuot, P., Gruss, A. and Poyart, C. Brinster et al. reply. Nature 463, E4-E4.
    • Brinster, S.1    Lamberet, G.2    Staels, B.3
  • 51
    • 38549140094 scopus 로고    scopus 로고
    • RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation
    • Gama-Castro S., et al. RegulonDB (version 6.0): gene regulation model of Escherichia coli K-12 beyond transcription, active (experimental) annotated promoters and Textpresso navigation. Nucleic Acids Res 2008, 36:D120-D124.
    • (2008) Nucleic Acids Res , vol.36
    • Gama-Castro, S.1
  • 52
    • 59649095559 scopus 로고    scopus 로고
    • Coordinated regulation of virulence during systemic infection of Salmonella enterica serovar Typhimurium
    • Yoon H., McDermott J.E., Porwollik S., McClelland M., Heffron F. Coordinated regulation of virulence during systemic infection of Salmonella enterica serovar Typhimurium. PLoS Pathog 2009, 5:e1000306.
    • (2009) PLoS Pathog , vol.5
    • Yoon, H.1    McDermott, J.E.2    Porwollik, S.3    McClelland, M.4    Heffron, F.5
  • 53
    • 0032870794 scopus 로고    scopus 로고
    • Effects of DksA and ClpP protease on sigma S production and virulence in Salmonella typhimurium
    • Webb C., Moreno M., Wilmes-Riesenberg M., Curtiss R., Foster J.W. Effects of DksA and ClpP protease on sigma S production and virulence in Salmonella typhimurium. Mol Microbiol 1999, 34:112-123.
    • (1999) Mol Microbiol , vol.34 , pp. 112-123
    • Webb, C.1    Moreno, M.2    Wilmes-Riesenberg, M.3    Curtiss, R.4    Foster, J.W.5
  • 54
    • 0035055316 scopus 로고    scopus 로고
    • Disruption of the genes for ClpXP protease in Salmonella enterica serovar Typhimurium results in persistent infection in mice, and development of persistence requires endogenous gamma interferon and tumor necrosis factor alpha
    • Yamamoto T., et al. Disruption of the genes for ClpXP protease in Salmonella enterica serovar Typhimurium results in persistent infection in mice, and development of persistence requires endogenous gamma interferon and tumor necrosis factor alpha. Infect Immun 2001, 69:3164-3174.
    • (2001) Infect Immun , vol.69 , pp. 3164-3174
    • Yamamoto, T.1
  • 55
    • 61649121489 scopus 로고    scopus 로고
    • The use of genomics in microbial vaccine development
    • Bambini S., Rappuoli R. The use of genomics in microbial vaccine development. Drug Discov Today 2009, 14:252-260.
    • (2009) Drug Discov Today , vol.14 , pp. 252-260
    • Bambini, S.1    Rappuoli, R.2
  • 56
    • 67650523946 scopus 로고    scopus 로고
    • Genomes2Drugs: identifies target proteins and lead drugs from proteome data
    • Toomey D., Hoppe H.C., Brennan M.P., Nolan K.B., Chubb A.J. Genomes2Drugs: identifies target proteins and lead drugs from proteome data. PLoS ONE 2009, 4:e6195.
    • (2009) PLoS ONE , vol.4
    • Toomey, D.1    Hoppe, H.C.2    Brennan, M.P.3    Nolan, K.B.4    Chubb, A.J.5
  • 57
    • 2942526958 scopus 로고    scopus 로고
    • Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen
    • Rollenhagen C., Sorensen M., Rizos K., Hurvitz R., Bumann D. Antigen selection based on expression levels during infection facilitates vaccine development for an intracellular pathogen. Proc Natl Acad Sci USA 2004, 101:8739-8744.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 8739-8744
    • Rollenhagen, C.1    Sorensen, M.2    Rizos, K.3    Hurvitz, R.4    Bumann, D.5
  • 58
    • 0036841283 scopus 로고    scopus 로고
    • Multiparameter selection of Helicobacter pylori antigens identifies two novel antigens with high protective efficacy
    • Sabarth N., Hurwitz R., Meyer T.F., Bumann D. Multiparameter selection of Helicobacter pylori antigens identifies two novel antigens with high protective efficacy. Infect Immun 2002, 70:6499-6503.
    • (2002) Infect Immun , vol.70 , pp. 6499-6503
    • Sabarth, N.1    Hurwitz, R.2    Meyer, T.F.3    Bumann, D.4
  • 59
    • 77957234612 scopus 로고    scopus 로고
    • Identification of in vivo-induced bacterial protein antigens during human infection with Salmonella enterica serovar Typhi
    • Harris Jb Fau - Baresch-Bernal, A. et al. Identification of in vivo-induced bacterial protein antigens during human infection with Salmonella enterica serovar Typhi.
    • Harris Jb Fau - Baresch-Bernal, A.1    et al2
  • 61
    • 77957236423 scopus 로고    scopus 로고
    • ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization
    • Pappalardo F Fau - Halling-Brown, M.D. et al. ImmunoGrid, an integrative environment for large-scale simulation of the immune system for vaccine discovery, design and optimization.
    • Pappalardo F Fau - Halling-Brown, M.D.1
  • 63
    • 67749145750 scopus 로고    scopus 로고
    • Identification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapy
    • Depontieu F.R., et al. Identification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapy. Proc Natl Acad Sci USA 2009, 106:12073-12078.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 12073-12078
    • Depontieu, F.R.1
  • 64
    • 0038433318 scopus 로고    scopus 로고
    • Immune responses dependent on antigen location in recombinant attenuated Salmonella typhimurium vaccines following oral immunization
    • Kang H.Y., Curtiss R. Immune responses dependent on antigen location in recombinant attenuated Salmonella typhimurium vaccines following oral immunization. FEMS Immunol Med Microbiol 2003, 37:99-104.
    • (2003) FEMS Immunol Med Microbiol , vol.37 , pp. 99-104
    • Kang, H.Y.1    Curtiss, R.2
  • 65
    • 34547624348 scopus 로고    scopus 로고
    • Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis
    • Mittrucker H.W., Steinhoff U., Kohler A., Krause M., Lazar D., Mex P., et al. Poor correlation between BCG vaccination-induced T cell responses and protection against tuberculosis. Proc Natl Acad Sci USA 2007, 104:12434-12439.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 12434-12439
    • Mittrucker, H.W.1    Steinhoff, U.2    Kohler, A.3    Krause, M.4    Lazar, D.5    Mex, P.6
  • 66
    • 77957237631 scopus 로고    scopus 로고
    • Proteins accessible to immune surveillance show significant T-cell epitope depletion: implications for vaccine design
    • Halling-Brown M Fau - Shaban, R. et al. Proteins accessible to immune surveillance show significant T-cell epitope depletion: implications for vaccine design.
    • Halling-Brown, M.1    Fau - Shaban, R.2
  • 67
    • 38449101120 scopus 로고    scopus 로고
    • Integration of biological networks and gene expression data using Cytoscape
    • Cline M.S., et al. Integration of biological networks and gene expression data using Cytoscape. Nat Protoc 2007, 2:2366-2382.
    • (2007) Nat Protoc , vol.2 , pp. 2366-2382
    • Cline, M.S.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.