At least four percent of the Salmonella typhimurium genome is required for fatal infection of mice

Infection and Immunity

Volumn 66, Issue 7, 1998, Pages 3372-3377

  Bowe, Frances ^a,c   Lipps, Craig J ^a   Tsolis, Renee M ^a,d   Groisman, Eduardo ^b   Heffron, Fred ^a   Kusters, Johannes G ^a,e  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d TEXAS A AND M UNIVERSITY   (United States)

^e VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BACTERIAL MUTATION; BACTERIAL VIRULENCE; FATALITY; GENE INSERTION; GENE ISOLATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; TYPHOID FEVER;

SALMONELLA TYPHIMURIUM;

EID: 0031869632     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.7.3372-3377.1998     Document Type: Article

References (43)

1. + dependent malic enzyme involved in pathogenicity. Microb. Pathog. 23:55-61.
2. Altschul S, F., W. Gish, W. Miller, E. W. Myers, and D. J. Lipman. 1990. Basic local alignment search tool. J. Mol. Biol. 215:403-410.
3. Amouroux, C., J. C. Lazzaroni, and R. Portalier. 1991. Isolation and characterization of extragenic suppressor mutants of the tolA-876 periplasmic-leaky allele in Escherichia coli K-12. FEMS Microbiol. Lett. 62:305-313.
4. Benson, N. R., and B. S. Goldman. 1992. Rapid mapping in Salmonella typhimurium with Mud-P22 prophages. J. Bacteriol. 174:1673-1681.
5. Blattner, F. R., G. R. Plunkett, C. A. Bloch, N. T. Perna, V. Burland, M. Riley, J. Collado-Vides, J. D. Glasner, C. K. Rode, G. F. Mayhew, J. Gregor, N. W. Davis, H. A. Kirkpatrick, M. A. Goeden, D. J. Rose, B. Mau, and Y. Shao. 1997. The complete genome sequence of Escherichia coli K-12. Science 277:1453-1462.
6. Buchmeier, N. A., and F. Heffron. 1989. Intracellular survival of wild-type Salmonella typhimurium and macrophage-sensitive mutants in diverse populations of macrophages. Infect. Immun. 57:1-7.
7. Burns, N., B. Grimwade, P. B. Ross-Macdonald, E. Y. Choi, K. Finberg, G. S. Roeder, and M. Snyder. 1994. Large-scale analysis of gene expression, protein localization, and gene disruption in Saccharomyces cerevisiae. Genes Dev. 8:1087-1105.
8. Carter, P. B., and F. M. Collins. 1974. The route of enteric infection in normal mice. J. Exp. Med. 139:1189-1203.
9. Casadaban, M. J., and S. Cohen. 1979. Lactose genes fused to exogenous promoters in one step using a Mu-lac bacteriophage: in vivo probe for transcriptional control sequences. Proc. Natl. Acad. Sci. USA 76:4530-4533.
10. Cornelis, G., C. Sluiters, C. Lambert de Rouvroit, and T. Michiels. 1989. Homology between VirF, the transcriptional activator of the Yersinia virulence regulon, and AraC, the Escherichia coli arabinose operon regulator. J. Bacteriol. 171:254-262.
11. Davis, R. W., D. Botstein, and J. R. Roth. 1982. Advanced bacterial genetics: a manual for genetic engineering. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, N.Y.
12. Fields, P. I., R. V. Swanson, C. G. Haidaris, and F. Heffron. 1986. Mutants of Salmonella typhimurium that cannot survive within the macrophage are avirulent. Proc. Natl. Acad. Sci. USA 83:5189-5193.
13. Finlay, B. B., M. N. Starnbach, C. L. Francis, B. A. D. Stocker, S. Chatfield, G. Dougan, and S. Falkow. 1988. Identification of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayer. Mol. Microbiol. 2:757-766.
14. Friedrich, M. J., N. E. Kinsey, J. Vila, and R. J. Kadner. 1993. Nucleotide sequence of a 13.9kb segment of the 90kb virulence plasmid of Salmonella typhimurium: the presence of fimbrial biosynthetic genes. Mol. Microbiol. 8: 543-558.
15. Gish, W., and D. J. States. 1993. Identification of protein coding regions by database similarity search. Nat. Genet. 3:266-272.
16. f formyltransterase severely impairs growth of Escherichia coli. J. Bacteriol. 174:4294-4301.
17. Gulig, P. A., and R. Curtiss III. 1987. Plasmid-associated virulence of Salmonella typhimurium. Infect. Immun. 55:2891-2901.
18. Hughes, K. and J. Roth. 1988. Transitory cis complementation: a method for providing transposition functions to defective transposons. Genetics 119:9-12.
19. Joe, A., C. S. Murray, and B. C. McBride. 1994. Nucleotide sequence of a Porphyromonas gingivalis gene encoding a surface-associated glutamate dehydrogenase and construction of a glutamate dehydrogenase-deficient isogenic mutant. Infect. Immun. 62:1358-1368.
20. Levengood, S. K., and R. E. Webster. 1989. Nucleotide sequences of the tolA and tolB genes and localization of their products, components of a multistep translocation system in Escherichia coli. J. Bacteriol. 171:6600-6609.
21. Levine, M. 1957. Mutations in the temperate phage P22 and lysogeny in Salmonella. Virology 3:22-41.
22. Liu, S.-L., A. Hessel, and K. E. Sanderson. 1993. The XbaI-BlnI-CeuI genomic cleavage map of Salmonella typhimurium LT2 determined by double digestion, end labelling, and pulsed-field gel electrophoresis. J. Bacteriol. 175:4104-4120.
23. Liu, S.-L., and K. E. Sanderson. 1992. A physical map of the Salmonella typhimurium LT2 genome made by using XbaI analysis. J. Bacteriol. 174: 1662-1672.
24. Lodge, J., G. R. Douce, I. I. Amin, A. J. Bolton, G. D. Martin, S. Chatfield, G. Dougan, N. L. Brown, and J. Stephen. 1995. Biological and genetic characterization of TnphoA mutants of Salmonella typhimurium TML in the context of gastroenteritis. Infect. Immun. 63:762-769.
25. Lottenberg, R., C. C. Broder, and M. D. P. Boyle. 1992. Cloning, sequence analysis, and expression in Escherichia coli of a streptococcal plasmin receptor. J. Bacteriol. 174:5204-5210.
26. Lundrigan, M. D., M. J. Friedrich, and R. J. Kadner. 1989. Nucleotide sequence of the Escherichia coli porin thermoregulatory gene envY. Nucleic Acids Res. 17:800.
27. Mackaness, G. B., R. V. Blanden, and F. M. Collins. 1966. Host-parasite relations in mouse typhoid. J. Exp. Med. 124:573-583.
28. Miller, V. L., and S. Falkow. 1988. Evidence for two genetic loci in Yersinia enterocolitica that can promote invasion of epithelial cells. Infect. Immun. 56: 1242-1248.
29. Miller, F. D., and C. L. Hershberger. 1984. A quantitative beta-galactosidase alpha-complementation assay for fusion proteins containing human insulin B-chain peptides. Gene 29:247-250.
30. Mizuuchi, K., and R. Craigie. 1986. Mechanism of bacteriophage Mu transposition. Annu. Rev. Genet. 20:385-429.
31. Nou, X., B. Skinner, B. Braaten, D. Blyn, D. Hirsch, and D. Low. 1993. Regulation of pyelonephritis-associated pili phase-variation in Escherichia coli: binding of the PapI and the Lrp regulatory proteins is controlled by DNA methylation. Mol. Microbiol. 7:545-553.
32. O'Callaghan, D., D. Maskell, F. W. Liew, C. F. Easmon, and G. Dougan. 1988. Characterization of aromatic- and purine-dependent Salmonella typhimurium: attenuation, persistence, and ability to induce protective immunity in BALB/c mice. Infect. Immun. 5:419-423.
33. Ochman, H., M. M. Medhora, D. Garza, and D. L. Hartl. 1990. Amplification of flanking DNA by inverse PCR, p. 219-227. In M. A. Innis, D. H. Gelfand, J. J. Sninsku, and T. J. White (ed.), PCR protocols. Academic Press, San Diego, Calif.
34. Pancholi, V., and V. A. Fischetti. 1993. Glyceraldehyde-3-phosphate dehydrogenase on the surface of group A streptococci is also an ADP-ribosylating enzyme. Proc. Natl. Acad. Sci. USA 90:8154-8158.
35. Reed, L. J., and H. Muench. 1938. A simple method for estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
36. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, N.Y.
37. Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463-5467.
38. Stainer, R. Y., J. L. Ingraham, M. L. Wheelis, and P. R. Painter. 1987. General microbiology, 5th ed. MacMillan, London, United Kingdom.
39. Stojiljkovic, I., R. Schonherr, and J. G. Kusters. 1995. Identification of the hopG gene, a component of Escherichia coli K-12 type II export system, and its conservation among different pathogenic Escherichia coli and Shigella isolates. J. Bacteriol. 177:1892-1895.
40. Tsai, C. M., and C. E. Frasch. 1982. A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels. Anal. Biochem. 119:113-119.
41. Tsolis, R. M., A. J. Bäumler, I. Stojiljkovic, and F. Heffron. 1995. Fur regulon of Salmonella typhimurium: identification of new iron-regulated genes. J. Bacteriol. 177:4628-4637.
42. Wang, X., and N. P. Higgins. 1994. "Muprints" of the lac operon demonstrate physiological control over the randomness of in vivo transposition. Mol. Microbiol. 12:665-677.
43. Wong, K. K., and M. McClelland. 1992. A BlnI restriction map of the Salmonella typhimurium LT2 genome. J. Bacteriol. 174:1656-1661.