Systemic but not local administration of retinoic acid reduces early transcript levels of pro-inflammatory cytokines after experimental spinal cord injury

Neuroscience Letters

Volumn 485, Issue 1, 2010, Pages 21-25

  van Neerven, S ^a,b,c,d   Mey, J ^c,d   Joosten, E A ^a,d   Steinbusch, H W ^b,d   van Kleef, M ^a   Marcus, M A E ^a   Deumens, R ^a,c,d  

^a MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

^c RWTH AACHEN UNIVERSITY   (Germany)

^d European Graduate School of Neuroscience   (Netherlands)

Author keywords

Cytokines; Inflammation; Nuclear hormone receptors

Indexed keywords

INTERLEUKIN 1BETA; INTERLEUKIN 6; MESSENGER RNA; RETINOIC ACID; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTUSION; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; RISK ASSESSMENT; SPINAL CORD INJURY;

ANIMALS; FEMALE; INFLAMMATION; INJECTIONS, INTRAPERITONEAL; INJECTIONS, SPINAL; INTERLEUKIN-1BETA; INTERLEUKIN-6; NEUROIMMUNOMODULATION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SPINAL CORD INJURIES; TRETINOIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77957231064     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.08.051     Document Type: Article

References (32)

1. Balmer J.E., Blomhoff R. Gene expression regulation by retinoic acid. J. Lipid Res. 2002, 43:1773-1808.
2. Camisa C., Eisenstat B., Ragaz A., Weissmann G. The effects of retinoids on neutrophil functions in vitro. J. Am. Acad. Dermatol. 1982, 6:620-629.
3. Choi B., Kim J., Jung J., Lee Y., Han M., Baek S., Kim B., Kim J., Oh S. Reduction of ischemia-induced cerebral injury by all-trans-retinoic acid. Exp. Brain Res. 2009, 193:581-589.
4. Dheen S., Jun Y., Yan Z., Tay S., Ling E. Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat. Glia 2005, 50:21-31.
5. Donnelly D., Popovich P. Inflammation and its role in neuroprotection, axonal regeneration and functional. Exp. Neurol. 2008, 209:378-388.
6. Genovese T., Mazzon E., Crisafulli C., Di Paola R., Muia C., Esposito E., Bramanti P., Cuzzocrea S. TNF-alpha blockage in a mouse model of SCI: evidence for improved outcome. Shock 2008, 29:32-41.
7. Gruner J.A. A monitored contusion model of spinal cord injury in the rat. J. Neurotrauma 1992, 9:123-126. discussion 126-128.
8. Hanson N., Leachman S. Safety issues in isotretinoin therapy. Semin. Cutan. Med. Surg. 2001, 20:166-183.
9. Harvey B., Shen H., Chen G., Yoshida Y., Wang Y. Midkine and retinoic acid reduce cerebral infarction induced by middle cerebral. Neurosci. Lett. 2004, 369:138-141.
10. Hathcock J.N., Hattan D.G., Jenkins M.Y., McDonald J.T., Sundaresan P.R., Wilkening V.L. Evaluation of vitamin A toxicity. Am. J. Clin. Nutr. 1990, 52:183-202.
11. Hull P.R., D'Arcy C. Isotretinoin use and subsequent depression and suicide: presenting the evidence. Am. J. Clin. Dermatol. 2003, 4:493-505.
12. Kampmann E., Johann S., van Neerven S., Beyer C., Mey J. Anti-inflammatory effect of retinoic acid on prostaglandin synthesis in cultured cortical astrocytes. J. Neurochem. 2008, 106:320-332.
13. Kim B.H., Kang K.S., Lee Y.S. Effect of retinoids on LPS-induced COX-2 expression and COX-2 associated PGE(2) release from mouse peritoneal macrophages and TNF-alpha release from rat peripheral blood mononuclear cells. Toxicol. Lett. 2004, 150:191-201.
14. Luo T., Wagner E., Grun F., Drager U.C. Retinoic acid signaling in the brain marks formation of optic projections, maturation of the dorsal telencephalon, and function of limbic sites. J. Comp. Neurol. 2004, 470:297-316.
15. Marchand F., Tsantoulas C., Singh D., Grist J., Clark A.K., Bradbury E.J., McMahon S.B. Effects of Etanercept and Minocycline in a rat model of spinal cord injury. Eur. J. Pain 2009, 13:673-681.
16. Mucida D., Park Y., Kim G., Turovskaya O., Scott I., Kronenberg M., Cheroutre H. Reciprocal TH17 and regulatory T cell differentiation mediated by retinoic acid. Science 2007, 317:256-260.
17. Na S., Kang B., Chung S., Han S., Ma X., Trinchieri G., Im S., Lee J., Kim T. Retinoids inhibit interleukin-12 production in macrophages through physical. J. Biol. Chem. 1999, 274:7674-7680.
18. Park S.W., Yi J.H., Miranpuri G., Satriotomo I., Bowen K., Resnick D.K., Vemuganti R. Thiazolidinedione class of peroxisome proliferator-activated receptor gamma agonists prevents neuronal damage, motor dysfunction, myelin loss, neuropathic pain, and inflammation after spinal cord injury in adult rats. J. Pharmacol. Exp. Ther. 2007, 320:1002-1012.
19. Patatanian E., Thompson D.F. Retinoic acid syndrome: a review. J. Clin. Pharm. Ther. 2008, 33:331-338.
20. Paterniti I., Genovese T., Mazzon E., Crisafulli C., Di Paola R., Galuppo M., Bramanti P., Cuzzocrea S. Liver X receptor agonist treatment regulates inflammatory response after spinal cord trauma. J. Neurochem. 2010, 112:611-624.
21. Raghavendra V., Tanga F., DeLeo J.A. Inhibition of microglial activation attenuates the development but not existing hypersensitivity in a rat model of neuropathy. J. Pharmacol. Exp. Ther. 2003, 306:624-630.
22. Sato Y., Meller R., Yang T., Taki W., Simon R. Stereo-selective neuroprotection against stroke with vitamin A derivatives. Brain Res. 2008, 19:188-192.
23. Schrage K., Koopmans G., Joosten E.A., Mey J. Macrophages and neurons are targets of retinoic acid signaling after spinal cord contusion injury. Eur. J. Neurosci. 2006, 23:285-295.
24. Shah P., Mudaliar S. Pioglitazone: side effect and safety profile. Expert Opin. Drug Saf. 2010, 9:347-354.
25. Shen H., Luo Y., Kuo C., Deng X., Chang C., Harvey B., Hoffer B., Wang Y. 9-Cis-retinoic acid reduces ischemic brain injury in rodents via bone. J. Neurosci. Res. 2009, 87:545-555.
26. Streit W.J., Semple-Rowland S.L., Hurley S.D., Miller R.C., Popovich P.G., Stokes B.T. Cytokine mRNA profiles in contused spinal cord and axotomized facial nucleus suggest a beneficial role for inflammation and gliosis. Exp. Neurol. 1998, 152(1):74-87.
27. Suh D.Y., Hunt T.K., Spencer E.M. Insulin-like growth factor-I reverses the impairment of wound healing induced by corticosteroids in rats. Endocrinology 1992, 131:2399-2403.
28. Tsai M.C., Wei C.P., Lee D.Y., Tseng Y.T., Tsai M.D., Shih Y.L., Lee Y.H., Chang S.F., Leu S.J. Inflammatory mediators of cerebrospinal fluid from patients with spinal cord injury. Surg. Neurol. 2008, 70(Suppl. 1). S1:19-24; discussion S11:24.
29. van Neerven S., Kampmann E., Mey J. RAR/RXR and PPAR/RXR signaling in neurological and psychiatric diseases. Prog. Neurobiol. 2008, 85:433-451.
30. van Neerven S., Regen T., Wolf D., Nemes A., Johann S., Beyer C., Hanisch U.K., Mey J. Inflammatory chemokine release of astrocytes in vitro is reduced by all-trans retinoic acid. J. Neurochem. 2010, 114(5):1511-1526.
31. Werner E.A., Deluca H.F. Retinoic acid is detected at relatively high levels in the CNS of adult rats. Am. J. Physiol. Endocrinol. Metab. 2002, 282:E672-E678.
32. Xu J., Drew P. 9-Cis-retinoic acid suppresses inflammatory responses of microglia and. J. Neuroimmunol. 2006, 171:135-144.