Modulation of immune response during canine distemper virus infection: Therapeutic and vaccine development implications;Modulación de la respuesta inmune durante la infección por virus distemper canino: Implicancias terapéuticas y en el desarrollo de vacunas

Archivos de Medicina Veterinaria

Volumn 42, Issue 2, 2010, Pages 15-28

  Cespedes P F ^a   Cruz, P ^a   Navarro, C O ^a  

^a UNIVERSITY OF CHILE   (Chile)

Author keywords

Canine distemper virus; Dendritic cells; Th1 immune response; Th17 immune response

Indexed keywords

AILUROPODA; AILUROPODA MELANOLEUCA; ANIMALIA; CANINE DISTEMPER VIRUS; FELIDAE;

EID: 77957168200     PISSN: 0301732X     EISSN: 07176201     Source Type: Journal    
DOI: None     Document Type: Article

References (88)

1. Abt M, E Gassert, S Schneider-Schaulies. 2009. Measles virus modulates chemokine release and chemotactic responses of dendritic cells. J Gen Virol 90, 909-914.
2. Aliberti J, O Schulz, D Pennington, H Tsujimura, C Reis e Sousa, K Ozato, A Sher. 2003. Essential role for ICSBP in the in vivo development of murine CD8+ dendritic cells. Blood 101, 305-310.
3. Alldinger S, W Baumgärtner, C Örvell. 1993. Restricted expression of viral surface proteins in canine distemper encephalitis. Acta Neuropathol 85, 635-645.
4. Alldinger S, A Wünschmann, W Baumgärtner, C Voss, E Kremmer. 1996. Up-regulation of major histocompatibility complex class II antigen expression in the central nervous system of dogs with spontaneous canine distemper virus encephalitis. Acta Neuropathol 92, 273-280.
5. Alldinger S, S Gröters, Q Miao, S Fonfara, E Kremmer, W Baumgärtner. 2006. Roles of an extracellular matrix (ECM) receptor and ECM processing enzymes in demyelinating canine distemper encephalitis. Dtsch Tierarztl Wochenschr 113, 151-156.
6. Baumgärtner W, C Örvell, M Reinacher. 1989. Naturally occurring canine distemper virus encephalitis: distribution and expression of viral polypeptides in nervous tissues. Acta Neuropathol 78, 504-512.
7. Baumgärtner W, RW Boyce, S Alldinger, MK Axthelm, SE Weisbrode, S Krakowka, K Gaedke. 1995a. Metaphyseal bone lesions in young dogs with systemic canine distemper virus infection. Vet Microbiol 44, 201-209.
8. Baumgärtner W, RW Boyce, SE Weisbrode, S Alldinger, MK Axthelm, S Krakowka. 1995b. Histologic and immunocytochemical characterization of canine distemper-associated metaphyseal bone lesions in young dogs following experimental infection. Vet Pathol 32, 702-709.
9. Beineke A, S Markus, J Borlak, T Thum, W Baumgärtner. 2008. Increase of pro-inflammatory cytokine expression in non-demyelinating early cerebral lesions in nervous canine distemper. Viral Immunol 21, 401-410.
10. Beineke A, C Puff, F Seehusen, W Baumgärtner. 2009. Pathogenesis and immunopathology of systemic and nervous canine Distemper. Vet Immunol Immunopathol 127, 1-18.
11. Bonami F, P Rudd, V von Messling. 2007. Disease duration determines canine distemper virus neurovirulence. J Virology 81, 1206612070.
12. Bronson E, SL Deem, C Sanchez, S Murray. 2007. Serologic response to a canarypox-vectored canine distemper virus vaccine in the giant panda (Ailuropoda melanoleuca). J Zoo Wildl Med 38, 363-366.
13. Calderon MG, P Remorini, O Periolo, M Iglesias, N Mattion, J La Torre. 2007. Detection by RT-PCR and genetic characterization of canine distemper virus from vaccinated and non-vaccinated dogs in Argentina. Vet Microbiol 125, 341-349.
14. Cocks BG, C-CJ Chang, JM Carballido, H Yssel, JE de Vries, G Aversa. 1995. A novel receptor involved in T-cell activation. Nature 376, 260-263.
15. Curran J, D Kolakofsky. 2000. Replication of paramyxoviruses. Adv Virus Res 54, 403-422.
16. Elia G, C Belloli, F Cirone, MS Lucente, M Caruso, V Martella, N Decaro, C Buonavoglia, P Ormas. 2008. In vitro efficacy of ribavirin against canine distemper virus. Antiviral Res 77, 108-113.
17. Frisk AL, W Baumgärtner, A Gröne. 1999. Dominating interleukin-10 mRNA expression induction in cerebrospinal fluid cells of dogs with natural canine distemper virus induced demyelinating and nondemyelinating CNS lesions. J Neuroimmunol 97, 102-109.
18. González PA, CE Prado, ED Leiva, LJ Carreño, SM Bueno, CA Riedel, AM Kalergis. 2008. Respiratory syncytial virus impairs T cell activation by preventing synapse assembly with dendritic cells. P Natl Acad Sci 105, 14999-15004.
19. Gröne A, S Fonfara, W Baumgärtner. 2002. Cell type-dependent cytokine expression after canine Distemper virus infection. Viral Immunol 15, 493-505.
20. Gurer C, T Strowig, F Brilot, M Pack, C Trumpfheller, F Arrey, CH Gyu Park, R Steinman, C Münz. 2008. Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood 112, 1231-1239.
21. Herrada A, F Contreras, N Marini, C Amador, P González, C Cortés, C Riedel, C Carvajal, F Figueroa, L Michea, C Fardella, A Kalergis. 2010. Aldosterone promotes autoimmune damage by enhancing Th17-mediated immunity. J Immunol 184, 191-202.
22. Hirama K, Y Goto, M Uema, Y Endo, R Miura, C Kai. 2004. Phylogenetic analysis of the hemagglutinin (H) gene of canine distemper viruses isolated from wild Masked Palm Civets (Paguma larvata). J Vet Med Sci 66, 1575-1578.
23. Hoover S, R Striker. 2008. Thiopurines inhibit bovine viral diarrhea virus production in a thiopurine methyltransferase-dependent manner. J Gen Virol 89, 1000-1009.
24. Hoyland JA, JA Dixon, JL Berry, M Davies, PL Selby, AP Mee. 2003. A comparison of in situ hybridisation, reverse transcriptase-polymerase chain reaction (RT-PCR) and in situ-RT-PCR for the detection of canine distemper virus RNA in Paget's disease. J Virol Methods 109, 253-259.
25. Iruretagoyena M, S Sep?lveda, JP Lezana, M Hermoso, M Bronfman, M Guti?rrez, S Jacobelli, A Kalergis. 2006. Inhibition of Nuclear Factor-κB enhances the capacity of immature dendritic cells to induce antigen-specific tolerance in experimental autoimmune encephalomyelitis. J Pharmacol Exp Ther 318, 59-67.
26. Kerdiles YM, B Cherif, JC Marie, N Tremillon, B Blanquier, G Libeau, A Diallo, TFWild, MBVilliers, B Horvat. 2006. Immunomodulatory properties of morbillivirus nucleoproteins. Viral Immunol 19, 324-334.
27. Krakowka S, MK Axthelm, GC Johnsen. 1985. Canine Distemper virus. In: Olsen RG, Krakowka S, Blakeslee JR (eds). Comparative pathobiology of viral diseases. Vol 2. CRC Press Inc, Boca Ratón, Florida, USA, Pp 137-164.
28. Lampert PW. 1978. Autoimmune and virus-induced demyelinating diseases. A review. Am J Pathos 91, 176-208.
29. Lan NT, R Yamaguchi, A Inomata, Y Furuya, K Uchida, S Sugano, S Tateyama. 2005. Comparative analyses of canine distemper viral isolates from clinical cases of canine Distemper in vaccinated dogs. Vet Microbiol 115, 32-42.
30. Lappas M, M Permezel, GE Rice. 2003. N-acetyl-cysteine inhibits phospholipid metabolism, proinflammatory cytokine release, protease activity, and Nuclear Factor-?B deoxyribonucleic acid-binding activity in human fetal membranes in vitro. J Clin Endocrinol Metab 88, 1723-1729.
31. Larson LJ, RD Schultz. 2006. Effect of vaccination with recombinant canine distemper virus vaccine immediately before exposure under shelter-like conditions. Vet Ther 7, 113-118.
32. Larson LJ, RD Schultz. 2007. Three years duration of immunity in dogs vaccinated with a canarypox-vectored recombinant canine distemper virus vaccine. Vet Ther 8, 101-106.
33. Lee J-I, GJ Burckart. 1998. Nuclear factor kappa B: important transcription factor and therapeutic target. J Clin Pharmacol 38, 981-993.
34. Markus S, K Failing, W Baumgärtner. 2002. Increased expression of pro-inflammatory cytokines and lack of up-regulation of anti-inflammatory cytokines in early distemper CNS lesions. J Neuroimmunol 125, 30-41.
35. Martella V, A Pratelli, F Cirone, N Zizzo, N Decaro, A Tinelli, M Foti, C Buonavoglia. 2002. Detection and genetic characterization of canine distemper virus (CDV) from free-ranging red foxes in Italy. Mol Cell Probe 16, 77-83.
36. Martella V, F Cirone, G Elia, E Lorusso, N Decaro, M Campolo, C Desario, MS Lucente, AL Bellacicco, M Blixenkrone-Møller, LE Carmichael, C Buonavoglia. 2006. Heterogeneity within the hemagglutinin genes of canine distemper virus (CDV) strains detected in Italy. Vet Microbiol 116, 301-309.
37. Mee AP, PT Sharpe. 1993. Dogs, distemper and Paget's disease. Bioessays 15, 783-789.
38. Mee AP, C May, D Bennett, PT Sharpe. 1995a. Generation of multinucleated osteoclast-like cells from canine bone marrow: effects of canine distemper virus. Bone 17, 47-55.
39. Mee AP, JA Hoyland, P Baird, D Bennett, PT Sharpe. 1995b. Canine bone marrow cell cultures infected with canine distemper virus: an in vitro model of Paget's disease. Bone 17, 461S-466S.
40. Mee AP, JA Dixon, JA Hoyland, M Davies, PL Selby, EB Mawer. 1998. Detection of canine distemper virus in 100% of Paget's disease samples by in situ-reverse transcriptase-polymerase chain reaction. Bone 23, 171-175.
41. Miao Q, W Baumgärtner, K Failing, S Alldinger. 2003. Phase-dependent expression of matrix metalloproteinases and their inhibitors in demyelinating canine distemper encephalitis. Acta neuropathol 106, 486-494.
42. Mochizuki M, M Hashimoto, S Hagiwara, Y Yoshida, S Ishiguro. 1999. Genotypes of canine distemper virus determined by analysis of the hemagglutinin genes of recent isolates from dogs in Japan. J Clin Microbiol 37, 2936-2942.
43. Mok H, S Lee, TJ Utley, BE Shepherd, VV Polosukhin, ML Collier, NL Davis, RE Johnston, JE Crowe Jr. 2007. Venezuelan equine encephalitis virus replicon particles encoding respiratory syncytial virus surface glycoproteins induce protective mucosal responses in mice and cotton rats. J Virol 81, 13710-13722.
44. Moreira R, M Stutzin. 2005. Estudio de la mortalidad de zorros en la IV Región. Boletín Veterinario Oficial. SAG, Chile N° 3, 1-8.
45. Moro L, AS Martins, CM Alves, FG Santos, HL Del Puerto, AC Vasconcelos. 2003. Apoptosis in the cerebellum of dogs with distemper. J Vet Med B 50, 221-225.
46. Müller CF, RS Fatzer, K Beck, M Vandevelde, A Zurbriggen. 1995. Studies on canine distemper virus persistence in the central nervous system. Acta Neuropathol 89, 438-445.
47. Noh K, H Lim, S-K Moon, JS Kang, WJ Lee, D Lee, Y-I Hwang. 2005. Mega-dose Vitamin C modulates T cell functions in Balb/c mice only when administered during T cell activation. Immunol Lett 98, 63-72.
48. Nolting J, C Daniel, S Reuter, C Stuelten, P Li, H Sucov, B-G Kim, JJ Letterio, K Kretschmer, H-J Kim, H von Boehmer. 2009. Retinoic acid can enhance conversion of naive into regulatory T cells independently of secreted cytokines. J Exp Med 206, 2131-2139.
49. Orlando EA, I Imbschweiler, I Gerhauser, W Baumgärtner, K Wewetzer. 2008. In vitro characterization and preferential infection by canine distemper virus of glial precursors with Schwann cell characteristics from adult canine brain. Neuropathol Appl Neurobiol 34, 621-637.
50. Pardo IDR, GC Johnson, SB Kleiboeker. 2005. Phylogenetic characterization of canine distemper viruses detected in naturally infected dogs in North America. J Clin Microbiol 43, 5009-5017.
51. Pardo MC, P Tanner, J Bauman, K Silver, L Fischer. 2007. Immunization of puppies in the presence of maternally derived antibodies against canine distemper virus. J Comp Pathol 137, 72S-75S.
52. Pillet S, V von Messling. 2009. Canine distemper virus selectively inhibits apoptosis progression in infected immune cells. J Virol 12, 6279-6287.
53. Placek K, M Coffre, S Maiella, E Bianchi, L Rogge. 2009. Genetic and epigenetic networks controlling T helper 1 cell differentiation. Immunology 127, 155-162.
54. Racke MK, D Burnett, S-H Pak, PS Albert, B Cannella, CS Raine, DE McFarlin, DE Scotts. 1995. Retinoid treatment of experimental allergic encephalomyelitis: il-4 production correlates with improved disease course. J Immunol 154, 450-458.
55. Rodeheffer C, V von Messling, S Milot, F Lepine, AR Manges, BJ Ward. 2007. Disease manifestations of canine distemper virus infection in ferrets are modulated by vitamin A status. J Nutr 137, 1916-1922.
56. Rouxel RN, N Svitek, V von Messling. 2009. A chimeric measles virus with canine distemper envelope protects ferrets from lethal distemper challenge. Vaccine 27, 4961-4966.
57. Rudd P, R Cattaneo, V von Messling. 2006. Canine Distemper virus uses both the anterograde and the hematogenous pathway for neuroinvasion. J Virol 80, 9361-9370.
58. Sakurada S, T Kato, T Okamoto. 1996. Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin. Int Immunol 8, 1483-1493.
59. Schneider-Schaulies S, IM Klagge, V ter Meulen. 2003. Dendritic cells and measles virus infection. Curr Top Microbiol Immunol 276, 77-101.
60. Schobesberger M, A Summerfield, MG Doherr, A Zurbriggen, C Griot. 2005. Canine distemper virus-induced depletion of uninfected lymphocytes is associated with apoptosis. Vet Immunol Immunopathol 104, 33-44.
61. Selby PL, M Davies, AP Mee. 2006. Canine distemper virus induces human osteoclastogenesis through NF-kappaB and sequestosome 1/P62 activation. J Bone Miner Res 21, 1750-1756.
62. Sereda AD, KE Gavrilov, LG Fugina. 1999. Distemper of carnivore: proliferative activity of lymphocytes in sick and vaccinated dogs. Vopr Virusol 44, 257-261.
63. Servet-Delprat C, PO Vidalain, H Valentin, C Rabourdin-Combe. 2003. Measles virus and dendritic cell functions: how specific response cohabits with immunosuppression. Curr Top Microbiol Immunol 276, 103-123.
64. Sidhu MS, W Husar, SD Cook, PC Dowling, SA Udem. 1993. Canine distemper terminal and intergenic non-protein coding nucleotide sequences: completion of the entire CDV genome sequence. Virology 193, 66-72.
65. Sidorenko SP, EA Clark. 2003. The dual-function CD150 receptor subfamily: the viral attraction. Nat Immunol 4, 19-24.
66. Steinman RM, D Hawiger, MC Nussenzweig. 2003. Tolerogenic dendritic cells. Annu Rev Immunol 21, 685-711.
67. Strasser A, B May, A Teltscher, E Wistrela, H Niedermüller. 2003. Immune modulation following immunization with polyvalent vaccines in dogs. Vet Immunol Immunopathol 94, 113-121.
68. Summers BA, MJ Appel. 1994. Aspects of canine distemper virus and measles virus encephalomyelitis. Neuropathol Appl Neurobiol 20, 525-534.
69. Suter SE, MB Chein, V von Messling, B Yip, R Cattaneo, W Vernau, BR Madewell, CA London. 2005. In vitro canine distemper virus infection of canine lymphoid cells: a prelude to oncolytic therapy for lymphoma. Clin Cancer Res 11, 1579-1587.
70. Tatsuo H, N Ono, Y Yanagi. 2001. Morvilliviruses use signaling lymphocyte activation molecules (CD150) as cellular receptors. J Virol 75, 5842-5850.
71. Tipold A, Moore P, A Zurbriggen, I Burgener, G Barben, M Vandevelde. 1999. Early T cell response in the central nervous system in canine distemper virus infection. Acta Neuropathol 97, 45-56.
72. Tipold A, M Vandevelde, R Wittek, P Moore, A Summerfield, A Zurbriggen. 2001. Partial protection and intrathecal invasion of CD8+ T cells in acute canine distemper virus infection. Vet Microbiol 83, 189-203.
73. Uema M, K Ohashi, C Wasaka, C Kai. 2004. Phylogenetic and restriction fragment length polymorphism analyses of hemagglutinin (H) protein of canine distemper virus isolates from domestic dogs in Japan. Virus Res 109, 59-63.
74. Vandevelde M. 2004. The pathogenesis of nervous distemper. Award Lecture, WSAVA/Waltham International Award for Scientific Achievement, WSAVA FECAVA HVMS World Congress Scientific Proceedings. Rhodes, Greece.
75. Vandevelde M, A Zurbriggen. 2005. Demyelination in canine distemper virus infection: a review. Acta Neuropathol 109, 56-68.
76. Verhasselt V, WV Berghe, N Vanderheyde, F Willems, G Haegeman, M Goldman. 1999. N-acetyl-L-cysteine inhibits primary human T cell responses at the dendritic cell level: association with NF-κB inhibition. J Immunol 162, 2569-2574.
77. Von Boehmer H. 2007. Oral tolerance: is it all retinoic acid? J Exp Med 204, 1737-1739.
78. Von Messling V, G Zimmer, G Herrler, L Haas, R Cattaneo. 2001. The hemagglutinin of canine distemper virus determines tropism and cytopathogenicity. J Virol 75, 6418-6427.
79. Von Messling V, C Springfeld, P Devaux, R Cattaneo. 2003. A ferret model of canine distemper virus virulence and inmunosuppression. J Virol 77, 12579-12591.
80. Von Messling V, D Milosevic, R Cattaneo. 2004. Tropism illuminated: lymphocyte-based pathways blazed by lethal morbillivirus through the host immune system. P Natl Acad Sci 101, 14216-14221.
81. Von Messling V, N Oezguen, Q Zheng, S Vongpunsawad, W Braun, R Cattaneo. 2005. Nearby clusters of hemagglutinin residues sustain SLAM-dependent canine distemper virus entry in peripheral blood mononuclear cells. J Virol 79, 5857-5862.
82. Von Messling V, N Svitek, R Cattaneo. 2006. Receptor (SLAM[CD150]) recognition and the V protein sustain swift lymphocyte-based invasion of mucosal tissue and lymphatic organs by a morvillivirus. J Virol 80, 6084-6092.
83. Wang J, TW Huizinga, RE Toes. 2009. De novo generation and enhanced suppression of human CD4+CD25+ regulatory T cells by retinoic acid. J Immunol 183, 4119-4126.
84. Wünschmann A, S Alldinger, E Kremmer, W Baumgärtner. 1999. Identification of CD4+ and CD8+ T cell subsets and B cells in the brain of dogs with spontaneous acute, subacute-, and chronicdemyelinating distemper encephalitis. Vet Immunol Immunopathol 67, 101-116.
85. Wünschmann A, E Kremmer, W Baumgärtner. 2000. Phenotypical characterization of T and B cell areas in lymphoid tissues of dogs with spontaneous distemper. Vet Immunol Immunopathol 73, 83-98.
86. Xiang Z, A Dayal, MA Jensen, BGW Arnason. 1998. All-trans retinoic acid potentiates the ability of interferon beta-1b to augment suppressor cell function in Multiple Sclerosis. Arch Neurol 55, 315-321.
87. Yokota A, HTakeuchi, N Maeda,Y Ohoka, C Kato, S-Y Song, M Iwata. 2009. GM-CSF and IL-4 synergistically trigger dendritic cells to acquire retinoic acid-producing capacity. Int Immunol 21, 361-377.
88. Zhao J, X Yan, W Wu. 2008. Genetic variations and cellular receptors of canine distemper virus-a review. Wei Sheng Wu Xue Bao 48, 986-991.