MIP-1β, a novel biomarker for in vitro sensitization test using human monocytic cell line

Toxicology in Vitro

Volumn 20, Issue 5, 2006, Pages 736-742

  Hirota, Morihiko ^a   Moro, Osamu ^a  

^a SHISEIDO RESEARCH CENTER   (Japan)

Author keywords

Alternative methods; CD86; In vitro skin sensitization; MIP 1 ; THP 1

Indexed keywords

1 CHLORO 2,4 DINITROBENZENE; 2 MERCAPTOBENZOTHIAZOLE; BENZALKONIUM CHLORIDE; BIOLOGICAL MARKER; CD86 ANTIGEN; COBALT SULFATE; DODECYL SULFATE SODIUM; MACROPHAGE INFLAMMATORY PROTEIN 1BETA; MESSENGER RNA; NICKEL SULFATE; PHENYLENEDIAMINE; 4 PHENYLENEDIAMINE; 4-PHENYLENEDIAMINE; BETA CHEMOKINE; CATHEPSIN B; CCL4 PROTEIN, HUMAN; HEME OXYGENASE 1; INTERLEUKIN 1; MACROPHAGE INFLAMMATORY PROTEIN 1; NICKEL; PHENYLENEDIAMINE DERIVATIVE;

ARTICLE; CELL LINE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MONOCYTE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SECRETION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY ANALYSIS; SKIN SENSITIZATION; UPREGULATION; BIOSYNTHESIS; DNA MICROARRAY; DRUG EFFECT; GENETICS; METABOLISM; SKIN;

ANTIGENS, CD86; BIOLOGICAL MARKERS; CATHEPSIN B; CELL LINE; CHEMOKINES, CC; DINITROCHLOROBENZENE; HEME OXYGENASE-1; HUMANS; INTERLEUKIN-1; MACROPHAGE INFLAMMATORY PROTEIN-1; MONOCYTES; NICKEL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHENYLENEDIAMINES; SKIN;

EID: 33745479556     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2005.10.013     Document Type: Article

References (32)

1. Acevedo F., Serra M.A., Ermolli M., Clerici L., and Vesterberg O. Nickel-induced proteins in human HaCaT keratinocytes: annexin II and phosphoglycerate kinase. Toxicology 159 (2001) 33-41
2. Aeby P., Wyss C., Beck H., Griem P., Scheffler H., and Goebel C. Characterization of the sensitizing potential of chemicals by in vitro analysis of dendritic cell activation and skin penetration. Journal of Investigative Dermatology 122 (2004) 1154-1164
3. Aiba S., Terunuma A., Manome H., and Tagami H. Dendritic cells differently respond to haptens and irritants by their production of cytokines and expression of co-stimulatory molecules. European Journal of Immunology 27 (1997) 3031-3038
4. Aiba S., and Tagami H. Dendritic cell activation induced by various stimuli, e.g. exposure to microorganisms, their products, cytokines, and simple chemicals as well as adhesion to extracellular matrix. Journal of Immunological Science 20 (1999) 1-13
5. 2 and 2,4-dinitrochlorobenzene. Journal of Investigative Dermatology 120 (2003) 390-399
6. Ashikaga T., Hoya M., Itagaki H., Katumura Y., and Aiba S. Evaluation of CD86 expression and MHC class II molecule internalization in THP-1 human monocyte cells as predictive endpoints for contact sensitizers. Toxicology In Vitro 16 (2002) 711-716
7. Basketter D.A., Evans P., Feilder R.J., Gerberick G.F., Dearman R.J., and Kimber I. Local lymph node assay-validation and use in practice. Food and Chemical Toxicology 40 (2002) 593-598
8. Becker D., Kolde G., Reske K., and Knop J. An in vitro endocytotic activation of murine epidermal langerhans cells under the influence of contact allergens. Journal of Immunological Methods 169 (1994) 195-204
9. Boisleve F., Kerdine-Romer S., Rougier-Larzat N., and Pallardy M. Nickel and DNCB induce CCR7 expression on Human dendritic cells through different signaling pathways: role of TNF-α and MAPK. Journal of Investigative Dermatology 123 (2004) 494-502
10. Cheng R.Y., Zhao A., Alvord W.G., Powell D.A., Bare R.M., Masuda A., Takahashi T., Anderson L.M., and Kasprzak K.S. Gene expression dose-response changes in microarrays after exposure of human peripheral lung epithelial cells to nickel(II). Toxicology and Applied Pharmacology 191 (2003) 22-39
11. Coutant K.D., de Brugerolle de Fraissinette A., Cordier A., and Ulrich P. Modulation of the activity of human monocyte-derived dendritic cells by chemical haptens, a metal allergen, and a staphylococcal superantigen. Toxicological Sciences 52 (1999) 189-198
12. Fiebiger E., Meraner P., Weber E., Fang I.F., Stingl G., Ploegh H., and Maurer D. Cytokines regulate proteolysis in major histocompatibility complex class II-dependent antigen presentation by dendritic cells. Journal of Experimental Medicine 193 (2001) 881-892
13. + dendritic cell phenotype. Archives of Dermatological Research 293 (2001) 147-158
14. Hulette B.A., Ryan C.A., and Gerberick G.F. Elucidating changes in surface marker expression of dendritic cells following chemical allergen treatment. Toxicology and Applied Pharmacology 182 (2002) 226-233
15. Keyse S.M., and Tyrrell R.M. Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. Proceedings of the National Academy of Sciences of the United States of America 86 (1989) 99-103
16. Kimber I., Dearman R.J., Basketter D.A., Ryan C.A., and Gerberick G.F. The Local lymph node assay: past, present and future. Contact Dermatitis 47 (2002) 315-328
17. Li Q., Milo R., Panitch H., and Bever Jr. C.T. Effect of propranolol and IFN-α on the induction of MHC class II expression and cytokine production by IFN-α in THP-1 human monocyte cells. Immunopharmacology and Immunotoxicology 20 (1988) 39-61
18. Loetsche P., Seitz M., Clark-Lewis I., Baggiolini M., and Moser B. Monocyte chemotactic proteins MCP-1, MCP-2, and MCP-3 are major attractants for human CD4+ and CD8+ T lymphocytes. FASEB Journal 8 (1994) 1055-1060
19. Magnusson B., and Kligman A.M. The identification of contact allergens by animal assay. The guinea pig maximization test. Journal of Investigative Dermatology 52 (1969) 268-276
20. Mossmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. Journal of Immunological Methods 65 (1983) 55-63
21. Murata M., Gong P., Suzuki K., and Koizumi S. Differential metal response and regulation of human heavy metal-inducible genes. Journal of Cellular Physiology 180 (1999) 105-113
22. National Toxicology Program, 1999. The murine local lymph node assay: a test method for assessing the allergic contact dermatitis potential of chemicals/compounds. Available from: .
23. Proost P., Wuyts A., Conings R., Lenaerts J.P., Put W., and Van Damme J. Purification and identification of natural chemokines. Methods 10 (1996) 82-92
24. Raport C.J., Gosling J., Schweickart V.L., Gray P.W., and Charo I.F. Molecular cloning and functional characterization of a novel human CC chemokine receptor (CCR5) for RANTES, MIP-1 beta, and MIP-1 alpha. Journal of Biological Chemistry 271 (1996) 17161-17166
25. Rizzardini M., Terao M., Falciani F., and Cantoni L. Cytokine induction of haem oxygenase mRNA in mouse liver. Interleukin 1 transcriptionally activates the haem oxygenase gene. Biochemical Journal 290 (1993) 343-347
26. Sunderman Jr. F.W. Metal induction of heme oxygenase. Annals of the New York Academy of Sciences 514 (1987) 65-80
27. Sundstrom C., and Nilsson K. Establishment and characterization of a human histiocytic lymphoma cell line (U-937). International Journal of Cancer 17 (1976) 565-577
28. Taub D.D., Sayers T.J., Carter C.R., and Ortaldo J.R. Alpha and beta chemokines induce NK cell migration and enhance NK-mediated cytolysis. Journal of Immunology 15 155 (1995) 3877-3888
29. Tedla N., Wang H.W., McNeil H.P., Di Girolamo N., Hampartzoumian T., Wakefield D., and Lloyd A. Regulation of T lymphocyte trafficking into lymph nodes during an immune response by the chemokines macrophage inflammatory protein (MIP)-1 alpha and MIP-1 beta. Journal of Immunology 161 (1998) 5663-5672
30. Tsuchiya S., Yamabe M., Yamaguchi Y., Kobayashi Y., Konno T., and Tada K. Establishment and characterization of a human acute monocytic leukemia cell line. International Journal of Cancer 26 (1980) 171-176
31. Uguccioni M., D'Apuzzo M., Loetscher M., Dewald B., and Baggiolini M. Actions of the chemotactic cytokines MCP-1, MCP-2, MCP-3, RANTES, MIP-1 alpha and MIP-1 beta on human monocytes. European Journal of Immunology 25 (1995) 64-68
32. Yoshida Y., Sakaguchi H., Ito Y., Okuda M., and Suzuki H. Evaluation of the skin sensitization potential of chemicals using expression of co-stimulatory molecules, CD54 and CD86, on the naïve THP-1 cell line. Toxicology In Vitro 17 (2003) 221-228