-
1
-
-
0028025654
-
A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily
-
Apfel R, et al. (1994) A novel orphan receptor specific for a subset of thyroid hormone-responsive elements and its interaction with the retinoid/thyroid hormone receptor subfamily. Mol Cell Biol 14:7025-7035.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 7025-7035
-
-
Apfel, R.1
-
2
-
-
0028918963
-
OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor
-
Teboul M, et al. (1995) OR-1, a member of the nuclear receptor superfamily that interacts with the 9-cis-retinoic acid receptor. Proc Natl Acad Sci USA 92:2096-2100.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 2096-2100
-
-
Teboul, M.1
-
3
-
-
0031042762
-
Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR
-
Willy PJ, Mangelsdorf DJ (1997) Unique requirements for retinoid-dependent transcriptional activation by the orphan receptor LXR. Genes Dev 11:289-298.
-
(1997)
Genes Dev
, vol.11
, pp. 289-298
-
-
Willy, P.J.1
Mangelsdorf, D.J.2
-
4
-
-
0033524420
-
Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta
-
Janowski BA, et al. (1999) Structural requirements of ligands for the oxysterol liver X receptors LXRalpha and LXRbeta. Proc Natl Acad Sci USA 96:266-271.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 266-271
-
-
Janowski, B.A.1
-
5
-
-
0013199471
-
Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha
-
Peet DJ, et al. (1998) Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha. Cell 93:693-704.
-
(1998)
Cell
, vol.93
, pp. 693-704
-
-
Peet, D.J.1
-
6
-
-
15744401435
-
Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion
-
DOI 10.1074/jbc.M411080200
-
Yu L, et al. (2005) Expression of ABCG5 and ABCG8 is required for regulation of biliary cholesterol secretion. J Biol Chem 280:8742-8747. (Pubitemid 40409561)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.10
, pp. 8742-8747
-
-
Yu, L.1
Gupta, S.2
Xu, F.3
Liverman, A.D.B.4
Moschetta, A.5
Mangelsdorf, D.J.6
Repa, J.J.7
Hobbs, H.H.8
Cohen, J.C.9
-
7
-
-
0034669025
-
Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta
-
Repa JJ, et al. (2000) Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. Genes Dev 14:2819-2830.
-
(2000)
Genes Dev
, vol.14
, pp. 2819-2830
-
-
Repa, J.J.1
-
8
-
-
0037192797
-
Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors
-
Joseph SB, et al. (2002) Direct and indirect mechanisms for regulation of fatty acid synthase gene expression by liver X receptors. J Biol Chem 277:11019-11025.
-
(2002)
J Biol Chem
, vol.277
, pp. 11019-11025
-
-
Joseph, S.B.1
-
9
-
-
0037428442
-
Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis
-
Cao G, et al. (2003) Antidiabetic action of a liver x receptor agonist mediated by inhibition of hepatic gluconeogenesis. J Biol Chem 278:1131-1136.
-
(2003)
J Biol Chem
, vol.278
, pp. 1131-1136
-
-
Cao, G.1
-
10
-
-
77950597894
-
Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytes
-
Lo Sasso G, et al. (2010) Down-regulation of the LXR transcriptome provides the requisite cholesterol levels to proliferating hepatocytes. Hepatology 51:1334-1344.
-
(2010)
Hepatology
, vol.51
, pp. 1334-1344
-
-
Lo Sasso, G.1
-
11
-
-
33746176754
-
Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist
-
Chuu CP, et al. (2006) Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist. Cancer Res 66:6482-6486.
-
(2006)
Cancer Res
, vol.66
, pp. 6482-6486
-
-
Chuu, C.P.1
-
12
-
-
64349083106
-
The oxysterol receptor LXR inhibits proliferation of human breast cancer cells
-
Vedin LL, Lewandowski SA, Parini P, Gustafsson JA, Steffensen KR (2009) The oxysterol receptor LXR inhibits proliferation of human breast cancer cells. Carcinogenesis 30:575-579.
-
(2009)
Carcinogenesis
, vol.30
, pp. 575-579
-
-
Vedin, L.L.1
Lewandowski, S.A.2
Parini, P.3
Gustafsson, J.A.4
Steffensen, K.R.5
-
13
-
-
33947367803
-
Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells
-
Wente W, Brenner MB, Zitzer H, Gromada J, Efanov AM (2007) Activation of liver X receptors and retinoid X receptors induces growth arrest and apoptosis in insulin-secreting cells. Endocrinology 148:1843-1849.
-
(2007)
Endocrinology
, vol.148
, pp. 1843-1849
-
-
Wente, W.1
Brenner, M.B.2
Zitzer, H.3
Gromada, J.4
Efanov, A.M.5
-
14
-
-
57249094223
-
Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest
-
Meng ZX, et al. (2009) Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest. Diabetologia 52:125-135.
-
(2009)
Diabetologia
, vol.52
, pp. 125-135
-
-
Meng, Z.X.1
-
15
-
-
70350724700
-
Liver X receptors interfere with cytokine-induced proliferation and cell survival in normal and leukemic lymphocytes
-
Geyeregger R, et al. (2009) Liver X receptors interfere with cytokine-induced proliferation and cell survival in normal and leukemic lymphocytes. J Leukoc Biol 86:1039-1048.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 1039-1048
-
-
Geyeregger, R.1
-
16
-
-
58849147447
-
Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice
-
Kim HJ, Andersson LC, Bouton D, Warner M, Gustafsson JA (2009) Stromal growth and epithelial cell proliferation in ventral prostates of liver X receptor knockout mice. Proc Natl Acad Sci USA 106:558-563.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 558-563
-
-
Kim, H.J.1
Andersson, L.C.2
Bouton, D.3
Warner, M.4
Gustafsson, J.A.5
-
17
-
-
34547475143
-
Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor
-
Gong H, et al. (2007) Estrogen deprivation and inhibition of breast cancer growth in vivo through activation of the orphan nuclear receptor liver X receptor. Mol Endocrinol 21:1781-1790.
-
(2007)
Mol Endocrinol
, vol.21
, pp. 1781-1790
-
-
Gong, H.1
-
18
-
-
0031963294
-
Cancer statistics, 1998
-
Landis SH, Murray T, Bolden S, Wingo PA (1998) Cancer statistics, 1998. CA Cancer J Clin 48:6-29.
-
(1998)
CA Cancer J Clin
, vol.48
, pp. 6-29
-
-
Landis, S.H.1
Murray, T.2
Bolden, S.3
Wingo, P.A.4
-
19
-
-
0035572863
-
Epidemiology and molecular pathology of gallbladder cancer
-
Lazcano-Ponce EC, et al. (2001) Epidemiology and molecular pathology of gallbladder cancer. CA Cancer J Clin 51:349-364.
-
(2001)
CA Cancer J Clin
, vol.51
, pp. 349-364
-
-
Lazcano-Ponce, E.C.1
-
21
-
-
0026667397
-
Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates
-
Henson DE, Albores-Saavedra J, Corle D (1992) Carcinoma of the gallbladder. Histologic types, stage of disease, grade, and survival rates. Cancer 70:1493-1497.
-
(1992)
Cancer
, vol.70
, pp. 1493-1497
-
-
Henson, D.E.1
Albores-Saavedra, J.2
Corle, D.3
-
22
-
-
0024544133
-
Gallstone growth, size, and risk of gallbladder cancer: An interracial study
-
Lowenfels AB, Walker AM, Althaus DP, Townsend G, Domellöf L (1989) Gallstone growth, size, and risk of gallbladder cancer: An interracial study. Int J Epidemiol 18:50-54.
-
(1989)
Int J Epidemiol
, vol.18
, pp. 50-54
-
-
Lowenfels, A.B.1
Walker, A.M.2
Althaus, D.P.3
Townsend, G.4
Domellöf, L.5
-
23
-
-
67650539345
-
Long term hormone therapy for perimenopausal and postmenopausal women
-
CD004143
-
Farquhar C, Marjoribanks J, Lethaby A, Suckling JA, Lamberts Q (2009) Long term hormone therapy for perimenopausal and postmenopausal women. Cochrane Database Syst Rev 2:CD004143.
-
(2009)
Cochrane Database Syst Rev
, vol.2
-
-
Farquhar, C.1
Marjoribanks, J.2
Lethaby, A.3
Suckling, J.A.4
Lamberts, Q.5
-
24
-
-
0036100518
-
Post-menopausal hormonal therapy and gallbladder cancer risk
-
Gallus S, et al. (2002) Post-menopausal hormonal therapy and gallbladder cancer risk. Int J Cancer 99:762-763.
-
(2002)
Int J Cancer
, vol.99
, pp. 762-763
-
-
Gallus, S.1
-
25
-
-
49149114649
-
Gallbladder disease and use of transdermal versus oral hormone replacement therapy in postmenopausal women: Prospective cohort study
-
Million Women Study Collaborators
-
Liu B, et al.; Million Women Study Collaborators (2008) Gallbladder disease and use of transdermal versus oral hormone replacement therapy in postmenopausal women: prospective cohort study. Br Med J 337:a386.
-
(2008)
Br Med J
, vol.337
-
-
Liu, B.1
-
26
-
-
0029967274
-
Preneoplastic lesions and gallbladder cancer: An estimate of the period required for progression
-
Roa I, et al. (1996) Preneoplastic lesions and gallbladder cancer: An estimate of the period required for progression. Gastroenterology 111:232-236.
-
(1996)
Gastroenterology
, vol.111
, pp. 232-236
-
-
Roa, I.1
-
28
-
-
4544297463
-
Gallbladder cancer: Lessons from a rare tumour
-
Wistuba II, Gazdar AF (2004) Gallbladder cancer: lessons from a rare tumour. Nat Rev Cancer 4:695-706.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 695-706
-
-
Wistuba, I.I.1
Gazdar, A.F.2
-
29
-
-
0020352386
-
Relation of adenoma to carcinoma in the gallbladder
-
Kozuka S, Tsubone N, Yasui A, Hachisuka K (1982) Relation of adenoma to carcinoma in the gallbladder. Cancer 50:2226-2234.
-
(1982)
Cancer
, vol.50
, pp. 2226-2234
-
-
Kozuka, S.1
Tsubone, N.2
Yasui, A.3
Hachisuka, K.4
-
30
-
-
54449087073
-
Pancreatic exocrine insufficiency in LXRbeta-/- Mice is associated with a reduction in aquaporin-1 expression
-
Gabbi C, et al. (2008) Pancreatic exocrine insufficiency in LXRbeta-/- mice is associated with a reduction in aquaporin-1 expression. Proc Natl Acad Sci USA 105:15052-15057.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 15052-15057
-
-
Gabbi, C.1
-
32
-
-
73449143836
-
Zonula occludens-1, occludin, and E-cadherin protein expression in biliary tract cancers
-
Németh Z, et al. (2009) Zonula occludens-1, occludin, and E-cadherin protein expression in biliary tract cancers. Pathol Oncol Res 15:533-539.
-
(2009)
Pathol Oncol Res
, vol.15
, pp. 533-539
-
-
Németh, Z.1
-
33
-
-
34247120155
-
Frequent occurrence of abnormal E-cadherin/beta-catenin protein expression in advanced gallbladder cancers and its association with decreased apoptosis
-
Hirata K, et al. (2006) Frequent occurrence of abnormal E-cadherin/beta-catenin protein expression in advanced gallbladder cancers and its association with decreased apoptosis. Oncology 71:102-110.
-
(2006)
Oncology
, vol.71
, pp. 102-110
-
-
Hirata, K.1
-
34
-
-
0034852853
-
The E-cadherin/catenin complex: An important gatekeeper in breast cancer tumorigenesis and malignant progression
-
Berx G, Van Roy F (2001) The E-cadherin/catenin complex: an important gatekeeper in breast cancer tumorigenesis and malignant progression. Breast Cancer Res 3:289-293.
-
(2001)
Breast Cancer Res
, vol.3
, pp. 289-293
-
-
Berx, G.1
Van Roy, F.2
-
35
-
-
0032956426
-
Cadherin-catenin expression in primary colorectal cancer: A survival analysis
-
Hugh TJ, et al. (1999) Cadherin-catenin expression in primary colorectal cancer: a survival analysis. Br J Cancer 80:1046-1051.
-
(1999)
Br J Cancer
, vol.80
, pp. 1046-1051
-
-
Hugh, T.J.1
-
36
-
-
0033784843
-
The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression
-
Cano A, et al. (2000) The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression. Nat Cell Biol 2:76-83.
-
(2000)
Nat Cell Biol
, vol.2
, pp. 76-83
-
-
Cano, A.1
-
37
-
-
7444259771
-
Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells
-
Fukuchi J, Kokontis JM, Hiipakka RA, Chuu CP, Liao S (2004) Antiproliferative effect of liver X receptor agonists on LNCaP human prostate cancer cells. Cancer Res 64:7686-7689.
-
(2004)
Cancer Res
, vol.64
, pp. 7686-7689
-
-
Fukuchi, J.1
Kokontis, J.M.2
Hiipakka, R.A.3
Chuu, C.P.4
Liao, S.5
-
38
-
-
57249095662
-
Suppression of beta-catenin signaling by liver X receptor ligands
-
Uno S, et al. (2009) Suppression of beta-catenin signaling by liver X receptor ligands. Biochem Pharmacol 77:186-195.
-
(2009)
Biochem Pharmacol
, vol.77
, pp. 186-195
-
-
Uno, S.1
-
39
-
-
0035150432
-
Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2
-
Lee SK, et al. (2001) Two distinct nuclear receptor-interaction domains and CREB-binding protein-dependent transactivation function of activating signal cointegrator-2. Mol Endocrinol 15:241-254.
-
(2001)
Mol Endocrinol
, vol.15
, pp. 241-254
-
-
Lee, S.K.1
-
40
-
-
44049101411
-
RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with Smad2 and Smad3
-
Antonson P, et al. (2008) RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with Smad2 and Smad3. J Biol Chem 283:8995-9001.
-
(2008)
J Biol Chem
, vol.283
, pp. 8995-9001
-
-
Antonson, P.1
-
41
-
-
2442676504
-
An immunohistochemical study of the expression of adhesion molecules in gallbladder lesions
-
Choi YL, et al. (2004) An immunohistochemical study of the expression of adhesion molecules in gallbladder lesions. J Histochem Cytochem 52:591-601.
-
(2004)
J Histochem Cytochem
, vol.52
, pp. 591-601
-
-
Choi, Y.L.1
-
42
-
-
0034087471
-
Factors affecting morphogenesis of rabbit gallbladder epithelial cells cultured in collagen gels
-
Mori M, Miyazaki K (2000) Factors affecting morphogenesis of rabbit gallbladder epithelial cells cultured in collagen gels. Cell Tissue Res 300:331-344.
-
(2000)
Cell Tissue Res
, vol.300
, pp. 331-344
-
-
Mori, M.1
Miyazaki, K.2
-
43
-
-
0032846119
-
Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: Involvement of transforming growth factor beta1
-
Gohongi T, et al. (1999) Tumor-host interactions in the gallbladder suppress distal angiogenesis and tumor growth: Involvement of transforming growth factor beta1. Nat Med 5:1203-1208.
-
(1999)
Nat Med
, vol.5
, pp. 1203-1208
-
-
Gohongi, T.1
-
44
-
-
50949125238
-
Genetic susceptibility of epidermal growth factor +61A>G and transforming growth factor beta1 -509C>T gene polymorphisms with gallbladder cancer
-
Vishnoi M, Pandey SN, Modi DR, Kumar A, Mittal B (2008) Genetic susceptibility of epidermal growth factor +61A>G and transforming growth factor beta1 -509C>T gene polymorphisms with gallbladder cancer. Hum Immunol 69:360-367.
-
(2008)
Hum Immunol
, vol.69
, pp. 360-367
-
-
Vishnoi, M.1
Pandey, S.N.2
Modi, D.R.3
Kumar, A.4
Mittal, B.5
-
45
-
-
0032520915
-
Mutations of the DPC4/Smad4 gene in biliary tract carcinoma
-
Hahn SA, et al. (1998) Mutations of the DPC4/Smad4 gene in biliary tract carcinoma. Cancer Res 58:1124-1126.
-
(1998)
Cancer Res
, vol.58
, pp. 1124-1126
-
-
Hahn, S.A.1
-
46
-
-
64249097105
-
Use of oral contraceptives, intrauterine devices and tubal sterilization and cancer risk in a large prospective study, from 1996 to 2006
-
Dorjgochoo T, et al. (2009) Use of oral contraceptives, intrauterine devices and tubal sterilization and cancer risk in a large prospective study, from 1996 to 2006. Int J Cancer 124:2442-2449.
-
(2009)
Int J Cancer
, vol.124
, pp. 2442-2449
-
-
Dorjgochoo, T.1
-
47
-
-
0037183561
-
Accumulation of foam cells in liver X receptor-deficient mice
-
Schuster GU, et al. (2002) Accumulation of foam cells in liver X receptor-deficient mice. Circulation 106:1147-1153.
-
(2002)
Circulation
, vol.106
, pp. 1147-1153
-
-
Schuster, G.U.1
-
48
-
-
0035101931
-
Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice
-
Alberti S, et al. (2001) Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. J Clin Invest 107:565-573.
-
(2001)
J Clin Invest
, vol.107
, pp. 565-573
-
-
Alberti, S.1
|