PTHrP promotes colon cancer cell migration and invasion in an integrin α6β4-dependent manner through activation of Rac1

Cancer Letters

Volumn 298, Issue 1, 2010, Pages 119-127

  Mula, Ramanjaneya V ^a   Bhatia, Vandanajay ^a   Falzon, Miriam ^a,b  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Integrin 6 4; Phosphatidylinositol 3 kinase; PTHrP; Rac1; Tiam1

Indexed keywords

ALPHA6BETA4 INTEGRIN; GROWTH FACTOR RECEPTOR; GUANINE NUCLEOTIDE EXCHANGE FACTOR; PARATHYROID HORMONE RELATED PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN TIAM1; RAC1 PROTEIN; UNCLASSIFIED DRUG; RAC1 PROTEIN, HUMAN; TIAM1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CELL CULTURE; CELL INVASION; CELL MIGRATION; COLON CANCER; CONTROLLED STUDY; CORRELATION FUNCTION; ENZYME ACTIVATION; HORMONE SYNTHESIS; HUMAN; HUMAN CELL; INHIBITION KINETICS; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; BIOSYNTHESIS; CELL MOTION; COLON TUMOR; GENETIC TRANSFECTION; GENETICS; METABOLISM; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; TUMOR INVASION;

CELL LINE, TUMOR; CELL MOVEMENT; COLONIC NEOPLASMS; GUANINE NUCLEOTIDE EXCHANGE FACTORS; HUMANS; INTEGRIN ALPHA6BETA4; NEOPLASM INVASIVENESS; PARATHYROID HORMONE-RELATED PROTEIN; RAC1 GTP-BINDING PROTEIN; TRANSFECTION;

EID: 77956912825     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.canlet.2010.06.009     Document Type: Article

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