A comparison of skin delivery of ferulic acid and its derivatives: Evaluation of their efficacy and safety

International Journal of Pharmaceutics

Volumn 399, Issue 1-2, 2010, Pages 44-51

  Zhang, Li Wen ^a   Al Suwayeh, Saleh A ^b   Hsieh, Pei Wen ^a   Fang, Jia You ^a,b  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

Author keywords

Antioxidant; Derivatives; Ferulic acid; Safety; Skin delivery

Indexed keywords

ANTIOXIDANT; BUFFER; CONIFERYL ALCOHOL; FERULIC ACID; ISOFERULIC ACID; REACTIVE OXYGEN METABOLITE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG SAFETY; ERYTHEMA; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIPID BILAYER; LIPOPHILICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SKIN PERMEABILITY; SKIN WATER LOSS; STRATUM CORNEUM;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTIOXIDANTS; BUFFERS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COUMARIC ACIDS; DERMATITIS, IRRITANT; FEMALE; HYDROGEN-ION CONCENTRATION; MICE; MICE, NUDE; MOLECULAR STRUCTURE; PHYSICOCHEMICAL PHENOMENA; SKIN; SKIN ABSORPTION; SKIN IRRITANCY TESTS; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 77956874445     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.07.054     Document Type: Article

References (39)

1. Alias L.M., Manoharan S., Vellaichamy L., Balakrishnan S., Ramachandran C.R. Protective effect of ferulic acid on 7,12-dimethylbenz[a]anthracene-induced skin carcinogenesis in Swiss albino mice. Exp. Toxicol. Pathol. 2009, 61:205-214.
2. Baert B., Deconinck E., Van Gele M., Slodicka M., Stoppie P., Bodé S., Slegers G., Vander Heyden Y., Lambert J., Beetens J., De Spiegeleer B. Transdermal penetration behaviour of drugs: CART-clustering, QSPR and selection of model compounds. Bioorg. Med. Chem. 2007, 15:6943-6955.
3. Barone E., Calabrese V., Mancuso C. Ferulic acid and its therapeutic potential as a hormetin for age-related diseases. Biogerontology 2009, 10:97-108.
4. Bedi M.K., Shenefelt P.D. Herbal therapy in dermatology. Arch. Dermatol. 2002, 138:232-242.
5. Bourne L.C., Rice-Evans C. Bioavailibility of ferulic acid. Biochem. Biophys. Res. Commun. 1998, 253:222-227.
6. Calabrese V., Calafato S., Puleo E., Cornelius C., Sapienza M., Morganti P., Mancuso Redox regulation of cellular stress response by ferulic acid ethyl ester in human dermal fibroblasts: role of vitagenes. Clin. Dermatol. 2008, 26:358-363.
7. Cal K. How does the type of vehicle influence the in vitro skin absorption and elimination kinetics of terpenes?. Arch. Dermatol. Res. 2006, 297:311-315.
8. Choquenet B., Couteau C., Paparis E., Coiffard L.J. Interest of ferulic acid ethyl ether in photoprotective creams: measure of efficacy by in vitro method. Nat. Prod. Res. 2008, 22:1467-1471.
9. Di Giacomo C., Acquaviva R., Sorrenti V., Vanella A., Grasso S., Barcellona M.L., Galvano F., Vanella L., Renis M. Oxidative and antioxidant status in plasma of runners: effect of oral supplementation with natural antioxidants. J. Med. Food 2009, 12:145-150.
10. Doan K., Bronaugh R.L., Yourick J.J. In vivo and in vitro skin absorption of lipophilic compounds, dibutyl phthalate, farnesol and geraniol in the hairless guinea pig. Food Chem. Toxicol. 2010, 48:18-23.
11. Donnelly R.F., Morrow D.I.J., McCarron P.A., Woolfson A.D., Morrissey A., Juzenas P., Juzeniene A., Iani V., McCarthy H.O., Moan J. Microneedle-mediated intradermal of 5-aminolevulinic acid: potential for enhanced topical photodynamic therapy. J. Control. Release 2008, 129:154-162.
12. Fang J.Y., Hwang T.L., Leu Y.L. Effect of enhancers and retarders on percutaneous absorption of flurbiprofen from hydrogels. Int. J. Pharm. 2003, 250:313-325.
13. Finnin B.C., Morgan T.M. Transdermal penetration enhancers: applications, limitations, and potential. J. Pharm. Sci. 1999, 88:955-958.
14. Frelichowska J., Bolzinger M., Pelletier J., Valour J., Chevalier Y. Topical delivery of lipophilic drugs from o/w Pickering emulsions. Int. J. Pharm. 2009, 371:56-63.
15. Godin B., Touitou E. Transdermal skin delivery: predictions for humans from in vivo, ex vivo and animal models. Adv. Drug Deliv. Rev. 2007, 59:1152-1161.
16. Gu M., Dhanalakshmi S., Mohan S., Singh R.P., Agarwal R. Silibinin inhibits ultraviolet B radiation-induced mitogenic and survival signaling, and associated biological responses in SKH-1 mouse skin. Carcinogenesis 2005, 26:1404-1413.
17. Gwak H.S., Chun I.K. Effect of vehicles and permeation enhancers on the in vitro percutaneous absorption of tenoxicam through hairless mouse skin. Int. J. Pharm. 2002, 236:57-64.
18. Heard C.M., Johnson S., Moss G., Thomas C.P. In vitro transdermal delivery of caffeine, theobromine, theophylline and catechin from extract of Guarana, Paullinia cupana. Int. J. Pharm. 2006, 317:26-31.
19. Huang Z.R., Hung C.F., Lin Y.K., Fang J.Y. In vitro and in vivo evaluation of topical delivery and potential dermal use of soy isoflavones genistein and daidzein. Int. J. Pharm. 2008, 364:36-44.
20. Hung C.F., Lin Y.K., Huang Z.R., Fang J.Y. Delivery of resveratrol, a red wine polyphenol, from solutions and hydrogels via the skin. Biol. Pharm. Bull. 2008, 31:955-962.
21. Hung C.F., Lin Y.K., Zhang L.W., Chang C.H., Fang J.Y. Topical delivery of silymarin constituents via the skin route. Acta Pharmacol. Sin. 2010, 31:118-126.
22. Jain A.K., Panchagnula R. Transdermal drug delivery of tricyclic antidepressants: effect of fatty acids. Methods Find. Exp. Clin. Pharmacol. 2003, 25:413-421.
23. Marti-Mestres G., Mestres J.P., Bres J., Martin S., Ramo J., Vian L. The " in vitro" percutaneous penetration of three antioxidant compounds. Int. J. Pharm. 2007, 331:139-144.
24. Murray J.C., Burch J.A., Streilein R.D., Iannacchione M.A., Hall R.P., Pinnell S.R. A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation. J. Am. Acad. Dermatol. 2008, 59:418-425.
25. Nenadis N., Zhang H.Y., Tsimidou M.Z. Structure-antioxidant activity relationship of ferulic acid derivatives: effect of carbon side chain characteristic groups. J. Agric. Food Chem. 2003, 51:1874-1879.
26. Oresajo C., Stephens T., Hino P.D., Law R.M., Yatskayer M., Foltis P., Pillai S., Pinnell S.R. Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin. J. Cosmet. Dermatol. 2008, 7:290-297.
27. Ou S., Kwok K.C. Ferulic acid: pharmaceutical functions, preparation and application in foods. J. Sci. Food Agric. 2004, 84:1261-1269.
28. Picone P., Bondi M.L., Montana G., Bruno A., Pitarresi G., Giammona G., Di Carlo M. Ferulic acid inhibits oxidative stress and cell death induced by Ab oligomers: improved delivery by solid lipid nanoparticles. Free Radic. Res. 2009, 43:1133-1145.
29. Pinnell S.R. Cutaneous photodamage, oxidative stress, and topical antioxidant protection. J. Am. Acad. Dermatol. 2003, 48:1-19.
30. Riviere J.E., Papich M.G. Potential and problems of developing transdermal patches for veterinary applications. Adv. Drug Deliv. Rev. 2001, 50:175-203.
31. Saija A., Tomaino A., Trombetta D., De Pasquale A., Uccella N., Barbuzzi T., Paolino D., Bonina F. In vitro and in vivo evaluation of caffeic and ferulic acids as topical photoprotective agents. Int. J. Pharm. 2000, 199:39-47.
32. Stratton S.P., Bangert J.L., Alberts D.S., Dorr R.T. Dermal toxicity of topical (-)epigallocatechin-3-gallate in BALB/c and SKH1 mice. Cancer Lett. 2000, 158:47-52.
33. Touitou E., Godin B., Karl Y., Bujanover S., Becker Y. Olei acid, a skin penetration enhancer, affects Langerhans cells and corneocytes. J. Control. Release 2002, 80:1-7.
34. Tournas J.A., Lin F.H., Burch J.A., Selim M.A., Monteiro-Riviere N.A., Zielinski J.E., Pinnell S.R. Ubiquinone, idebenone, and kinetin provide ineffective photoprotection to skin when compared to a topical antioxidant combination of vitamins C and E with ferulic acid. J. Invest. Dermatol. 2006, 126:1185-1187.
35. Vaddi H.K., Hamad M.O., Chen J., Banks S.L., Crooks P.A., Stinchcomb A.L. Human skin permeation of branched-chain 3-O-alkyl ester and carbonate prodrugs of naltrexone. Pharm. Res. 2005, 22:758-765.
36. Valko M., Rhodes C.J., Moncol J., Izakovic M., Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem. Biol. Interact. 2006, 160:1-40.
37. Vávrová K., Lorencová K., Klimentová J., Novotný J., Holý A., Hrabálek A. Transdermal and dermal delivery of adefovir: Effects of pH and permeation enhancers. Eur. J. Pharm. Biopharm. 2008, 69:597-604.
38. Wang J.J., Sung K.C., Huang J.F., Yeh C.H., Fang J.Y. Ester prodrugs of morphine improve transdermal drug delivery: a mechanistic study. J. Pharm. Pharmacol. 2007, 59:917-925.
39. Zhao Z., Egashira Y., Sanada H. Ferulic acid is quickly absorbed from rat stomach as the free form and then conjugated mainly in liver. J. Nutr. 2004, 134:3083-3088.