4-(3-Halo/amino-4,5-dimethoxyphenyl)-5-aryloxazoles and-N-methylimidazoles That Are cytotoxic against combretastatin a resistant tumor cells and vascular disrupting in a cisplatin resistant germ cell tumor model

Journal of Medicinal Chemistry

Volumn 53, Issue 18, 2010, Pages 6595-6602

  Schobert, Rainer ^b   Biersack, Bernhard ^b   Dietrich, Andrea ^a   Effenberger, Katharina ^b   Knauer, Sebastian ^b   Mueller, Thomas ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^b UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE DERIVATIVE; CISPLATIN; COLCHICINE; COMBRETASTATIN A4; HALOGEN; IMIDAZOLE DERIVATIVE; OXAZOLE DERIVATIVE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; TUBULIN; VINCRISTINE; 1-METHYL-5-(3''-AMINO-4''-METHOXYPHENYL)-4-(3'-CHLORO-4',5'-DIMETHOXYPHENYL)IMIDAZOLE; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; COMBRETASTATIN A4 PHOSPHATE; STILBENE DERIVATIVE; TUBULIN MODULATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CELL STRAIN MCF 7; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG SCREENING; DRUG TOLERABILITY; GERM CELL TUMOR; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; POLYMERIZATION; STRUCTURE ACTIVITY RELATION; TREATMENT RESPONSE; TUMOR BLEEDING; TUMOR MODEL; TUMOR REGRESSION; TUMOR XENOGRAFT; ANGIOGENESIS; ANIMAL; CANCER TRANSPLANTATION; CHEMISTRY; CHICK EMBRYO; DRUG EFFECTS; DRUG RESISTANCE; MALE; MULTIDRUG RESISTANCE; NEOPLASMS, GERM CELL AND EMBRYONAL; NEOVASCULARIZATION, PATHOLOGIC; NUDE MOUSE; SYNTHESIS; TESTICULAR NEOPLASMS; TUMOR CELL LINE; VASCULARIZATION; XENOGRAFT;

ANGIOGENESIS INHIBITORS; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHICK EMBRYO; CISPLATIN; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; IMIDAZOLES; MALE; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOPLASMS, GERM CELL AND EMBRYONAL; NEOVASCULARIZATION, PATHOLOGIC; NEOVASCULARIZATION, PHYSIOLOGIC; OXAZOLES; STILBENES; STRUCTURE-ACTIVITY RELATIONSHIP; TESTICULAR NEOPLASMS; TRANSPLANTATION, HETEROLOGOUS; TUBULIN MODULATORS;

EID: 77956765452     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm100345r     Document Type: Article

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