Extensive sphingolipid depletion does not affect lipid raft integrity or lipid raft localization and efflux function of the ABC transporter MRP1

Biochemical Journal

Volumn 430, Issue 3, 2010, Pages 519-529

  Klappe, Karin ^a   Dijkhuis, Anne Jan ^a   Hummel, Ina ^a   Van Dam, Annie ^b   Ivanova, Pavlina T ^c   Milne, Stephen B ^c   Myers, David S ^c   Brown, H Alex ^c   Permentier, Hjalmar ^b   Kok, Jan W ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Caveolin; Detergent free lipid raft; Flotillin; Multidrug resistance related protein 1 (MRP1); Neuro 2a cell; Src

Indexed keywords

CELL CULTURE; FATTY ACIDS; PHOSPHOLIPIDS;

CAVEOLIN; DETERGENT-FREE LIPID RAFT; FLOTILLIN; MULTIDRUG-RESISTANCE-RELATED PROTEIN 1 (MRP1); NEURO-2A CELL; SRC;

DETERGENTS;

CARBOXYFLUORESCEIN; CAVEOLIN 1; CHOLESTEROL; FLOTILLIN 1; GLYCEROPHOSPHOLIPID; LUBROL; MULTIDRUG RESISTANCE PROTEIN 1; PROTEIN TYROSINE KINASE; SERINE PALMITOYLTRANSFERASE; SPHINGOLIPID; 6-CARBOXYFLUORESCEIN; FATTY ACID; FLUORESCEIN DERIVATIVE; LIPID; MACROGOL DERIVATIVE; MONOUNSATURATED FATTY ACID; MULTIDRUG RESISTANCE PROTEIN; MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1; THERMOZYMOCIDIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CONTROLLED STUDY; DETERGENT RESISTANT MEMBRANE; FATTY ACID ANALYSIS; LIPID COMPOSITION; LIPID RAFT; MEMBRANE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; ANIMAL; CELL LINE; CELL MEMBRANE; CHEMISTRY; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; GENETICS; HUMAN; IMMUNOBLOTTING; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; CELL LINE, TUMOR; CHOLESTEROL; FATTY ACIDS; FATTY ACIDS, MONOUNSATURATED; FLUORESCEINS; GLYCEROPHOSPHOLIPIDS; HUMANS; IMMUNOBLOTTING; LIPIDS; MEMBRANE MICRODOMAINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; POLYETHYLENE GLYCOLS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPHINGOLIPIDS;

EID: 77956681340     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20091882     Document Type: Article

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