Plant-produced trastuzumab inhibits the growth of HER2 positive cancer cells

Journal of Agricultural and Food Chemistry

Volumn 58, Issue 18, 2010, Pages 10056-10063

  Grohs, Brittany M ^a   Niu, Yongqing ^a   Veldhuis, Linda J ^a   Trabelsi, Salma ^b   Garabagi, Freydoun ^a   Hassell, John A ^b   McLean, Michael D ^a   Hall, J Christopher ^a  

^a UNIVERSITY OF GUELPH   (Canada)

^b MCMASTER UNIVERSITY   (Canada)

Author keywords

Affinity purification; biopharming; biosimilar; HER2; Herceptin; Nicotiana benthamiana; plant produced mAb; therapeutic mAbs; trastuzumab

Indexed keywords

AFFINITY PURIFICATION; BIOPHARMING; BIOSIMILAR; HER2; HERCEPTIN; NICOTIANA BENTHAMIANA; PLANT-PRODUCED MAB; THERAPEUTIC MABS; TRASTUZUMAB;

AFFINITY CHROMATOGRAPHY; AGRICULTURE; AMMONIUM COMPOUNDS; CELLS; DISEASES; PLANT EXTRACTS; PURIFICATION;

MONOCLONAL ANTIBODIES;

ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR 2; HER2 PROTEIN, HUMAN; MONOCLONAL ANTIBODY; PLANTIBODY; TRASTUZUMAB;

ADENOCARCINOMA; ARTICLE; BIOREACTOR; BIOSYNTHESIS; CELL PROLIFERATION; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECT; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; TOBACCO; TRANSGENIC PLANT; TUMOR CELL LINE;

ADENOCARCINOMA; ANTIBODIES, MONOCLONAL; ANTINEOPLASTIC AGENTS; BIOREACTORS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; PLANTIBODIES; PLANTS, GENETICALLY MODIFIED; RECEPTOR, ERBB-2; TOBACCO;

NICOTIANA BENTHAMIANA;

EID: 77956630367     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/jf102284f     Document Type: Article

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