The steroid molting hormone ecdysone regulates sleep in adult Drosophila melanogaster

Genetics

Volumn 185, Issue 1, 2010, Pages 269-281

  Ishimoto, Hiroshi ^a   Kitamoto, Toshihiro ^a,b  

^a UNIVERSITY OF IOWA   (United States)

^b UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ECDYSONE; ECDYSONE RECEPTOR; ECDYSTERONE; ISOPROTEIN; STEROID RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DROSOPHILA MELANOGASTER; FEMALE; HOMEOSTASIS; MUSHROOM; MUTANT; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; SLEEP DEPRIVATION; SLEEP PATTERN; SLEEP TIME; SLEEP WAKING CYCLE; WAKEFULNESS; WILD TYPE; AGING; ANIMAL; DRUG EFFECT; GENETICS; HETEROZYGOTE; METABOLISM; MOLTING; MUSHROOM BODY; MUTATION; PHYSIOLOGY; SLEEP; TIME;

BASIDIOMYCOTA; CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; HEXAPODA;

AGING; ANIMALS; DROSOPHILA MELANOGASTER; ECDYSONE; ECDYSTERONE; FEMALE; HETEROZYGOTE; HOMEOSTASIS; MOLTING; MUSHROOM BODIES; MUTATION; PHENOTYPE; PROTEIN ISOFORMS; RECEPTORS, STEROID; SIGNAL TRANSDUCTION; SLEEP; TIME FACTORS;

EID: 77956626359     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.110.114587     Document Type: Article

References (50)

1. ANDRETIC, R., B. VAN SWINDEREN and R. J. GREENSPAN, 2005 Dopaminergic modulation of arousal in Drosophila. Curr. Biol. 15: 1165-1175.
2. ARANDA, A., and A. PASCUAL, 2001 Nuclear hormone receptors and gene expression. Physiol. Rev. 81: 1269-1304.
3. BENDER, M., F. B. IMAM, W. S. TALBOT, B. GANETZKY and D. S. HOGNESS, 1997 Drosophila ecdysone receptor mutations reveal functional differences among receptor isoforms. Cell 91: 777-788.
4. BENDER, M., G. E. CARNEY, A. A. WADE, T. R. LI, J. W. TRUMAN et al., 1998 Mutational dissection of the Drosophila ecdysone receptor (EcR) gene: EcR is required maternally for normal oogenesis and EcR-B isoforms are required for neuronal remodeling during metamorphosis. Dev. Biol. 198: 221.
5. BENINGTON, J. H., and M. G. FRANK, 2003 Cellular and molecular connections between sleep and synaptic plasticity. Prog. Neurobiol. 69: 71-101.
6. BUSZCZAK, M., M. R. FREEMAN, J. R. CARLSON, M. BENDER, L. COOLEY et al., 1999 Ecdysone response genes govern egg chamber development during mid-oogenesis in Drosophila. Development 126: 4581-4589.
7. CAMPBELL, S. S., and I. TOBLER, 1984 Animal sleep: a review of sleep duration across phylogeny. Neurosci. Biobehav. Rev. 8: 269-300.
8. CAYRE, M., C. STRAMBI, A. STRAMBI, P. CHARPIN and J. P. TERNAUX, 2000 Dual effect of ecdysone on adult cricket mushroom bodies. Eur. J. Neurosci. 12: 633-642.
9. CHUNG, B. Y., V. L. KILMAN, J. R. KEATH, J. L. PITMAN and R. ALLADA, 2009 The GABA(A) receptor RDL acts in peptidergic PDF neurons to promote sleep in Drosophila. Curr. Biol. 19: 386-390.
10. CIRELLI, C., and D. BUSHEY, 2008 Sleep and wakefulness in Drosophila melanogaster. Ann. NY Acad. Sci. 1129: 323-329.
11. EVANS, R. M., 1988 The steroid and thyroid hormone receptor superfamily. Science 240: 889-895.
12. FOLTENYI, K., R. J. GREENSPAN and J. W. NEWPORT, 2007 Activation of EGFR and ERK by rhomboid signaling regulates the consolidation and maintenance of sleep in Drosophila. Nat. Neurosci. 10: 1160-1167.
13. GILESTRO, G. F., and C. CIRELLI, 2009 pySolo: a complete suite for sleep analysis in Drosophila. Bioinformatics 25: 1466-1467.
14. GILESTRO, G. F., G. TONONI and C. CIRELLI, 2009 Widespread changes in synaptic markers as a function of sleep and wakefulness in Drosophila. Science 324: 109-112.
15. GREENSPAN, R. J., G. TONONI, C. CIRELLI and P. J. SHAW, 2001 Sleep and the fruit fly. Trends Neurosci. 24: 142-145.
16. HANDLER, A. M., 1982 Ecdysteroid titers during pupal and adult development in Drosophila melanogaster. Dev. Biol. 93: 73-82.
17. HARTMANN, E., 1973 Functions of Sleep. Yale Univ. Press, New Haven, CT.
18. HENDRICKS, J. C., S. M. FINN, K. A. PANCKERI, J. CHAVKIN, J. A. WILLIAMS et al., 2000 Rest in Drosophila is a sleep-like state. Neuron 25: 129-138.
19. HENDRICKS, J. C., S. LU, K. KUME, J. C. YIN, Z. YANG et al., 2003 Gender dimorphism in the role of cycle (BMAL1) in rest, rest regulation, and longevity in Drosophila melanogaster. J. Biol. Rhythms 18: 12-25.
20. HOLDEN, J. J., and D. T. SUZUKI, 1973 Temperature-sensitive mutations in Drosophila melanogaster. XII. The genetic and developmental effects of dominant lethals on chromosome 3. Genetics 73: 445-458.
21. HORNE, J. A., 1985 Sleep function, with particular reference to sleep deprivation. Ann. Clin. Res. 17: 199-208.
22. HUBER, R., S. L. HILL, C. HOLLADAY, M. BIESIADECKI, G. TONONI et al., 2004 Sleep homeostasis in Drosophila melanogaster. Sleep 27: 628-639.
23. ISHIMOTO, H., T. SAKAI and T. KITAMOTO, 2009 Ecdysone signaling regulates the formation of long-term courtship memory in adult Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 106: 6381-6386.
24. JOINER, W. J., A. CROCKER, B. H. WHITE and A. SEHGAL, 2006 Sleep in Drosophila is regulated by adult mushroom bodies. Nature 441: 757-760. (Pubitemid 43865222)
25. KRAFT, R., R. B. LEVINE and L. L. RESTIFO, 1998 The steroid hormone 20-hydroxyecdysone enhances neurite growth of Drosophila mushroom body neurons isolated during metamorphosis. J. Neurosci. 18: 8886-8899.
26. KUME, K., S. KUME, S. K. PARK, J. HIRSH and F. R. JACKSON, 2005 Dopamine is a regulator of arousal in the fruit fly. J. Neurosci. 25: 7377-7384.
27. LAVRANOS, G., R. ANGELOPOULOU, P. MANOLAKOU and M. BALLA, 2006 Hormonal and meta-hormonal determinants of sexual dimorphism. Coll. Antropol. 30: 659-663.
28. LEE, T., S. MARTICKE, C. SUNG, S. ROBINOW and L. LUO, 2000 Cell-autonomous requirement of the USP/EcR-B ecdysone receptor for mushroom body neuronal remodeling in Drosophila. Neuron 28: 807-818.
29. MACKIEWICZ, M., N. NAIDOO, J. E. ZIMMERMAN and A. I. PACK, 2008 Molecular mechanisms of sleep and wakefulness. Ann. NY Acad. Sci. 1129: 335-349.
30. NEUBUESER, D., J. T. WARREN, L. I. GILBERT and S. M. COHEN, 2005 molting defective is required for ecdysone biosynthesis. Dev. Biol. 280: 362-372.
31. OSTERWALDER, T., K. S. YOON, B. H. WHITE and H. KESHISHIAN, 2001 A conditional tissue-specific transgene expression system using inducible GAL4. Proc. Natl. Acad. Sci. USA 98: 12596-12601.
32. PARISKY, K. M., J. AGOSTO, S. R. PULVER, Y. SHANG, E. KUKLIN et al., 2008 PDF cells are a GABA-responsive wake-promoting component of the Drosophila sleep circuit. Neuron 60: 672-682.
33. PITMAN, J. L., J. J. MCGILL, K. P. KEEGAN and R. ALLADA, 2006 A dynamic role for the mushroom bodies in promoting sleep in Drosophila. Nature 441: 753-756. (Pubitemid 43865221)
34. RAIZEN, D. M., J. E. ZIMMERMAN, M. H. MAYCOCK, U. D. TA, Y. J. YOU et al., 2008 Lethargus is a Caenorhabditis elegans sleep-like state. Nature 451: 569-572.
35. RAUSCHENBACH, I. Y., M. Z. SUKHANOVA, A. HIRASHIMA, E. SUTSUGU and E. KUANO, 2000 Role of the ecdysteroid system in the regulation of Drosophila reproduction under environmental stress. Dokl. Biol. Sci. 375: 641-643.
36. ROMAN, G., K. ENDO, L. ZONG and R. L. DAVIS, 2001 P[Switch], a system for spatial and temporal control of gene expression in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA 98: 12602-12607.
37. SHAW, P. J., C. CIRELLI, R. J. GREENSPAN and G. TONONI, 2000 Correlates of sleep and waking in Drosophila melanogaster. Science 287: 1834-1837.
38. SIMON, A. F., C. SHIH, A. MACK and S. BENZER, 2003 Steroid control of longevity in Drosophila melanogaster. Science 299: 1407-1410.
39. SRIVASTAVA, D. P., E. J. YU, K. KENNEDY, H. CHATWIN, V. REALE et al., 2005 Rapid, nongenomic responses to ecdysteroids and catecholamines mediated by a novel Drosophila G-protein-coupled receptor. J. Neurosci. 25: 6145-6155.
40. STEIGER, A., 2003 Sleep and endocrinology. J. Intern. Med. 254: 13-22.
41. TALBOT, W. S., E. A. SWYRYD and D. S. HOGNESS, 1993 Drosophila tissues with different metamorphic responses to ecdysone express different ecdysone receptor isoforms. Cell 73: 1323-1337.
42. TERASHIMA, J., K. TAKAKI, S. SAKURAI and M. BOWNES, 2005 Nutritional status affects 20-hydroxyecdysone concentration and progression of oogenesis in Drosophila melanogaster. J. Endocrinol. 187: 69-79.
43. TRUMAN, J. W., and L. M. RIDDIFORD, 2002 Endocrine insights into the evolution of metamorphosis in insects. Annu. Rev. Entomol. 47: 467-500.
44. VELARDE, R. A., G. E. ROBINSON and S. E. FAHRBACH, 2009 Coordinated responses to developmental hormones in the Kenyon cells of the adult worker honey bee brain (Apis mellifera L.). J. Insect Physiol. 55: 59-69.
45. WALKER, V. K., K. L. WATSON, J. J. HOLDEN and C. G. H. STEEL, 1987 Vitellogenesis and fertility in Drosophila females with low ecdysteroid titres; the L(3)3DTS mutation. J. Insect Physiol. 33: 137-142.
46. YOSHIHARA, M., and K. ITO, 2000 Improved Gal4 screening kit for large-scale generation of enhancer-trap strains. Dros. Inf. Serv. 83: 199-202.
47. YUAN, Q., W. J. JOINER and A. SEHGAL, 2006 A sleep-promoting role for the Drosophila serotonin receptor 1A. Curr. Biol. 16: 1051-1062.
48. ZHENG, X., J. WANG, T. E. HAERRY, A. Y. WU, J. MARTIN et al., 2003 TGF-beta signaling activates steroid hormone receptor expression during neuronal remodeling in the Drosophila brain. Cell 112: 303-315.
49. ZIMMERMAN, J. E., N. NAIDOO, D. M. RAIZEN and A. I. PACK, 2008a Conservation of sleep: insights from non-mammalian model systems. Trends Neurosci. 31: 371-376.
50. ZIMMERMAN, J. E., D. M. RAIZEN, M. H. MAYCOCK, G. MAISLIN and A. I. PACK, 2008b A video method to study Drosophila sleep. Sleep 31: 1587-1598.