Sleep in Drosophila is regulated by adult mushroom bodies

Nature

Volumn 441, Issue 7094, 2006, Pages 757-760

  Joiner, William J ^a   Crocker, Amanda ^a   White, Benjamin H ^b   Sehgal, Amita ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ABLATION; BIOLOGICAL ORGANS; BRAIN; ELECTRIC EXCITATION; ENZYMES; METABOLISM;

CYCLIC-AMP-DEPENDENT PROTEIN KINASE (PKA); DROSOPHILA MELANOGASTER; ELECTRICAL SILENCING; VERTEBRATES;

BIOCHEMICAL ENGINEERING;

CYCLIC AMP DEPENDENT PROTEIN KINASE;

BEHAVIORAL RESPONSE; FLY; GENETIC ANALYSIS; METABOLISM; MUSHROOM; SLEEP;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN FUNCTION; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; ENZYME ACTIVITY; FEMALE; GENETIC TRAIT; LEARNING; MEMORY; METABOLISM; MUSHROOM BODY; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SLEEP; WAKEFULNESS;

BASIDIOMYCOTA; DROSOPHILA MELANOGASTER; VERTEBRATA;

EID: 33744546197     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature04811     Document Type: Article

References (30)

1. Hendricks, J. C. et al. Rest in Drosophila is a sleep-like state. Neuron 25, 129-138 (2000).
2. Shaw, P. J., Cirelli, C., Greenspan, R. J. & Tononi, G. Correlates of sleep and waking in Drosophila melanogaster. Science 287, 1834-1837 (2000).
3. Nitz, D. A., van Swinderen, B., Tononi, G. & Greenspan, R. J. Electrophysiological correlates of rest and activity in Drosophila melanogaster. Curr. Biol. 12, 1934-1940 (2002).
4. van Swinderen, B. & Greenspan, R. J. Salience modulates 20-30 Hz brain activity in Drosophila. Nature Neurosci. 6, 579-586 (2003).
5. Hendricks, J. C. et al. A non-circadian role for cAMP signaling and CREB activity in Drosophila rest homeostasis. Nature Neurosci. 4, 1108-1115 (2001).
6. Brand, A. H. & Perrimon, N. Targeted expression as a means of altering cell fates and generating dominant phenotypes. Development 118, 401-415 (1993).
7. Osterwalder, T., Yoon, K. S., White, B. H. & Keshishian, H. A conditional tissue-specific transgene expression system using inducible GAL4. Proc. Natl Acad. Sci. USA 98, 12596-12601 (2001).
8. Joiner, M. A. & Griffith, L. C. Mapping of the anatomical circuit of CaM kinase-dependent courtship conditioning in Drosophila. Learn. Mem. 6, 177-192 (1999).
9. Armstrong, J. D., de Belle, J. S., Wang, Z. & Kaiser, K. Metamorphosis of the mushroom bodies; large-scale rearrangements of the neural substrates for associative learning and memory in Drosophila. Learn. Mem. 5, 102-114 (1998).
10. Zhu, S., Chiang, A. S. & Lee, T. Development of the Drosophila mushroom bodies: elaboration, remodeling and spatial organization of dendrites in the calyx. Development 130, 2603-2610 (2003).
11. Crittenden, J. R., Skoulakis, E. M., Han, K. A., Kalderon, D. & Davis, R. L. Tripartite mushroom body architecture revealed by antigenic markers. Learn. Mem. 5, 38-51 (1998).
12. Mao, Z., Roman, G., Zong, L. & Davis, R. L. Pharmacogenetic rescue in time and space of the rutabaga memory impairment using Gene-Switch. Proc. Natl Acad. Sci. USA 101, 198-203 (2004).
13. Baines, R. A., Uhler, J. P., Thompson, A., Sweeney, S. T. & Bate, M. Altered electrical properties in Drosophila neurons developing without synaptic transmission. J. Neurosci. 21, 1523-1531 (2001).
14. + channel. Neuron 31, 699-711 (2001).
15. Luan, H. et al. Functional dissection of a neuronal network required for cuticle tanning and wing expansion in Drosophila. J. Neurosci. 26, 573-584 (2006).
16. Martin, J. R., Ernst, R. & Heisenberg, M. Mushroom bodies suppress locomotor activity in Drosophila melanogaster. Learn. Mem. 5, 179-191 (1998).
17. Helfrich-Forster, C., Wulf, J. & de Belle, J. S. Mushroom body influence on locomotor activity and circadian rhythms in Drosophila melanogaster. J. Neurogenet. 16, 73-109 (2002).
18. Cirelli, C. et al. Reduced sleep in Drosophila Shaker mutants. Nature 434, 1087-1092 (2005).
19. Walker, M. P. & Stickgold, R. Sleep-dependent learning and memory consolidation. Neuron 44, 121-133 (2004).
20. Frank, M. G., Issa, N. P. & Stryker, M. P. Sleep enhances plasticity in the developing visual cortex. Neuron 30, 275-287 (2001).
21. de Belle, J. S. & Heisenberg, M. Associative odor learning in Drosophila abolished by chemical ablation of mushroom bodies. Science 263, 692-695 (1994).
22. Dubnau, J., Grady, L., Kitamoto, T. & Tully, T. Disruption of neurotransmission in Drosophila mushroom body blocks retrieval but not acquisition of memory. Nature 411, 476-480 (2001).
23. McGuire, S. E., Le, P. T. & Davis, R. L. The role of Drosophila mushroom body signaling in olfactory memory. Science 293, 1330-1333 (2001).
24. Zars, T., Fischer, M., Schulz, R. & Heisenberg, M. Localization of a short-term memory in Drosophila. Science 288, 672-675 (2000).
25. McBride, S. M. et al. Mushroom body ablation impairs short-term memory and long-term memory of courtship conditioning in Drosophila melanogaster. Neuron 24, 967-977 (1999).
26. Liu, L., Wolf, R., Ernst, R. & Heisenberg, M. Context generalization in Drosophila visual learning requires the mushroom bodies. Nature 400, 753-756 (1999).
27. Tang, S. & Guo, A. Choice behavior of Drosophila facing contradictory visual cues. Science 294, 1543-1547 (2001).
28. Pascual, A. & Preat, T. Localization of long-term memory within the Drosophila mushroom body. Science 94, 1115-1117 (2001).
29. Huber, R. et al. Sleep homeostasis in Drosophila melanogaster. Sleep 27, 628-639 (2004).
30. Li, W., Ohlmeyer, J. T., Lane, M. E. & Kalderon, D. Function of protein kinase A in hedgehog signal transduction and Drosophila imaginai disc development. Cell 80, 553-562 (1995).