A single asparagine-linked glycosylation site of the severe acute respiratory syndrome coronavirus spike glycoprotein facilitates inhibition by mannose-binding lectin through multiple mechanisms

Journal of Virology

Volumn 84, Issue 17, 2010, Pages 8753-8764

  Zhou, Yanchen ^a   Lu, Kai ^a   Pfefferle, Susanne ^b   Bertram, Stephanie ^c   Glowacka, Ilona ^c   Drosten, Christian ^d   Pöhlmann, Stefan ^c   Simmons, Graham ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF BONN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN CONVERTING ENZYME 2; ASPARAGINE; CATHEPSIN; CD209 ANTIGEN; MANNOSE BINDING LECTIN; VIRUS GLYCOPROTEIN; CELL ADHESION MOLECULE; CELL SURFACE RECEPTOR; DC-SPECIFIC ICAM-3 GRABBING NONINTEGRIN; LECTIN; MEMBRANE PROTEIN; SPIKE GLYCOPROTEIN, CORONAVIRUS; VIRUS ENVELOPE PROTEIN;

ANIMAL CELL; ARTICLE; BINDING SITE; CONTROLLED STUDY; GLYCOSYLATION; HUMAN; MEMBRANE FUSION; MOUSE; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PSEUDOTYPING; RECEPTOR BINDING; SARS CORONAVIRUS; VIRUS ATTACHMENT; VIRUS ENTRY; VIRUS ENVELOPE; VIRUS INFECTION; VIRUS INHIBITION; ADULT; AGED; CELL LINE; CHEMISTRY; GENETICS; MALE; METABOLISM; MIDDLE AGED; PROTEIN MOTIF; SEVERE ACUTE RESPIRATORY SYNDROME; VIROLOGY;

SARS CORONAVIRUS;

ADULT; AGED; AMINO ACID MOTIFS; ASPARAGINE; CELL ADHESION MOLECULES; CELL LINE; GLYCOSYLATION; HUMANS; LECTINS, C-TYPE; MALE; MANNOSE-BINDING LECTIN; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SARS VIRUS; SEVERE ACUTE RESPIRATORY SYNDROME; VIRAL ENVELOPE PROTEINS; YOUNG ADULT;

EID: 77956625296     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00554-10     Document Type: Article

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