SARS coronavirus, but not human coronavirus NL63, utilizes cathepsin L to infect ACE2-expressing cells

Journal of Biological Chemistry

Volumn 281, Issue 6, 2006, Pages 3198-3203

  Huang, I Chueh ^a   Bosch, Berend Jan ^b   Li, Fang ^a   Li, Wenhui ^c   Kyoung, Hoa Lee ^a   Ghiran, Sorina ^a   Vasilieva, Natalya ^a   Dermody, Terence S ^d   Harrison, Stephen C ^a   Dormitzer, Philip R ^a   Farzan, Michael ^c   Rottier, Peter J M ^b   Choe, Hyeryun ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b UTRECHT UNIVERSITY   (Netherlands)

^c HARVARD MEDICAL SCHOOL   (United States)

^d VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELLS; DATA PROCESSING; MEDICAL PROBLEMS; PROTEINS;

ACE2-EXPRESSING CELLS; HCOV-NL63; LYSOSOMAL CYSTEINE PROTEASES; SARS CORONAVIRUS;

VIRUSES;

ALOXISTATIN; CATHEPSIN B; CATHEPSIN L; CATHEPSIN S; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; DIPEPTIDYL CARBOXYPEPTIDASE; GUANINE NUCLEOTIDE BINDING PROTEIN; PEPSTATIN; PHOSPHORAMIDON; SERINE PROTEINASE INHIBITOR; ANGIOTENSIN CONVERTING ENZYME 2; CARBOXYPEPTIDASE; CATHEPSIN; G PROTEIN, VESICULAR STOMATITIS VIRUS; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; VIRUS ENVELOPE PROTEIN;

ACIDIFICATION; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CORONAVIRUS; DRUG EFFECT; DRUG INHIBITION; ENZYME ACTIVITY; FILOVIRUS; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; SARS CORONAVIRUS; VESICULAR STOMATITIS VIRUS; ANIMAL; CELL LINE; CERCOPITHECUS; ENDOSOME; ENZYMOLOGY; GENETICS; LYSOSOME; METABOLISM; PHYSIOLOGY; RETROVIRUS; SPECIES DIFFERENCE; VERO CELL;

CORONAVIRUS; MARBURGVIRUS; SARS CORONAVIRUS; VESICULAR STOMATITIS VIRUS;

ANIMALS; CARBOXYPEPTIDASES; CATHEPSINS; CELL LINE; CERCOPITHECUS AETHIOPS; CORONAVIRUS; CYSTEINE ENDOPEPTIDASES; ENDOSOMES; GREEN FLUORESCENT PROTEINS; HUMANS; LYSOSOMES; MEMBRANE GLYCOPROTEINS; PEPTIDYL-DIPEPTIDASE A; RETROVIRIDAE; SARS VIRUS; SPECIES SPECIFICITY; VERO CELLS; VIRAL ENVELOPE PROTEINS;

EID: 33645635597     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M508381200     Document Type: Article

References (49)

1. Fouchier, R. A., Kuiken, T., Schutten, M., van Amerongen, G., van Doornum, G. J., van den Hoogen, B. G., Peiris, M., Lim, W., Stohr, K., and Osterhaus, A. D. (2003) Nature 423, 240
2. Kuiken, T., Fouchier, R. A., Schutten, M., Rimmelzwaan, G. F., van Amerongen, G., van Riel, D., Laman, J. D., de Jong, T., van Doornum, G., Lim, W., Ling, A. E., Chan, P. K., Tam, J. S., Zambon, M. C., Gopal, R., Drosten, C., van der Werf, S., Escriou, N., Manuguerra, J. C., Stohr, K., Peiris, J. S., and Osterhaus, A. D. (2003) Lancet 362, 263-270
3. Ksiazek, T. G., Erdman, D., Goldsmith, C. S., Zaki, S. R., Peret, T., Emery, S., Tong, S., Urbani, C., Comer, J. A., Lim, W., Rollin, P. E., Dowell, S. F., Ling, A. E., Humphrey, C. D., Shieh, W. J., Guarner, J., Paddock, C. D., Rota, P., Fields, B., DeRisi, J., Yang, J. Y., Cox, N., Hughes, J. M., LeDuc, J. W., Bellini, W. J., and Anderson, L. J. (2003) N. Engl. J. Med. 348, 1953-1966
4. Drosten, C., Gunther, S., Preiser, W., van der Werf, S., Brodt, H. R., Becker, S., Rabenau, H., Panning, M., Kolesnikova, L., Fouchier, R. A., Berger, A., Burguiere, A. M., Cinatl, J., Eickmann, M., Escriou, N., Grywna, K., Kramme, S., Manuguerra, J. C., Muller, S., Rickerts, V., Sturmer, M., Vieth, S., Klenk, H. D., Osterhaus, A. D., Schmitz, H., and Doerr, H. W. (2003) N. Engl. J. Med. 348, 1967-1976
5. Snijder, E. J., Bredenbeek, P. J., Dobbe, J. C., Thiel, V., Ziebuhr, J., Poon, L. L., Guan, Y., Rozanov, M., Spaan, W. J., and Gorbalenya, A. E. (2003) J. Mol. Biol. 331, 991-1004
6. Guan, Y., Peiris, J. S., Zheng, B., Poon, L. L., Chan, K. H., Zeng, F. Y., Chan, C. W., Chan, M. N., Chen, J. D., Chow, K. Y., Hon, C. C., Hui, K. H., Li, J., Li, V. Y., Wang, Y., Leung, S. W., Yuen, K. Y., and Leung, F. C. (2004) Lancet 363, 99-104
7. Woo, P. C., Lau, S. K., Chu, C. M., Chan, K. H., Tsoi, H. W., Huang, Y., Wong, B. H., Poon, R. W., Cai, J. J., Luk, W. K., Poon, L. L., Wong, S. S., Guan, Y., Peiris, J. S., and Yuen, K. Y. (2005) J. Virol. 79, 884-895
8. Kuba, K., Imai, Y., Rao, S., Gao, H., Guo, F., Guan, B., Huan, Y., Yang, P., Zhang, Y., Deng, W., Bao, L., Zhang, B., Liu, G., Wang, Z., Chappell, M., Liu, Y., Zheng, D., Leibbrandt, A., Wada, T., Slutsky, A. S., Liu, D., Qin, C., Jiang, C., and Penninger, J. M. (2005) Nat. Med. 11, 875-879
9. Li, W., Moore, M. J., Vasilieva, N., Sui, J., Wong, S. K., Berne, M. A., Somasundaran, M., Sullivan, J. L., Luzeriaga, C., Greenough, T. C., Choe, H., and Farzan, M. (2003) Nature 426, 450-454
10. Li, W., Zhang, C., Sui, J., Kuhn, J. H., Moore, M. J., Luo, S., Wong, S. K., Huang, I. C., Xu, K., Vasilieva, N., Murakami, A., He, Y., Marasco, W. A., Guan, Y., Choe, H., and Farzan, M. (2005) EMBO J. 24, 1634-1643
11. Hamming, I., Timens, W., Bulthuis, M. L., Lely, A. T., Navis, G. J., and van Goor, H. (2004) J. Pathol. 203, 631-637
12. Ding, Y., He, L., Zhang, Q., Huang, Z., Che, X., Hou, J., Wang, H., Shen, H., Qiu, L., Li, Z., Geng, J., Cai, J., Han, H., Li, X., Kang, W., Weng, D., Liang, P., and Jiang, S. (2004) J. Pathol. 203, 622-630
13. Yeager, C. L., Ashmun, R. A., Williams, R. K., Cardellichio, C. B., Shapiro, L. H., Look, A. T., and Holmes, K. V. (1992) Nature 357, 420-422
14. Tresnan, D. B., and Holmes, K. V. (1998) Adv. Exp. Med. Biol. 440, 69-75
15. van der Hoek, L., Pyrc, K., Jebbink, M. F., Vermeulen-Oost, W., Berkhout, R. J., Wolthers, K. C., Wertheim-van Dillen, P. M., Kaandorp, J., Spaargaren, J., and Berkhout, B. (2004) Nat. Med. 10, 368-373
16. Fouchier, R. A., Hartwig, N. G., Bestebroer, T. M., Niemeyer, B., de Jong, J. C., Simon, J. H., and Osterhaus, A. D. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 6212-6216
17. Esper, F., Weibel, C., Ferguson, D., Landry, M. L., and Kahn, J. S. (2005) J. Infect. Dis. 191, 492-498
18. Chiu, S. S., Chan, K. H., Chu, K. W., Kwan, S. W., Guan, Y., Poon, L. L., and Peiris, J. S. (2005) Clin. Infect. Dis. 40, 1721-1729
19. Hofmann, H., Pyrc, K., van der Hoek, L., Geier, M., Berkhout, B., and Pohlmann, S. (2005) Proc. Natl. Acad. Sci. U. S. A. 102, 7988-7993
20. Moes, E., Vijgen, L., Keyaerts, E., Zlateva, K., Li, S., Maes, P., Pyrc, K., Berkhout, B., van der Hoek, L., and Van Ranst, M. (2005) BMC Infect. Dis. 5, 6
21. Bastien, N., Anderson, K., Hart, L., Van Caeseele, P., Brandt, K., Milley, D., Hatchette, T., Weiss, E. C., and Li, Y. (2005) J. Infect. Dis. 191, 503-506
22. Arden, K. E., Nissen, M. D., Sloots, T. P., and Mackay, I. M. (2005) J. Med. Virol. 75, 455-462
23. Ebihara, T., Endo, R., Ma, X., Ishiguro, N., and Kikuta, H. (2005) J. Med. Virol. 75, 463-465
24. Gallagher, T. M., and Buchmeier, M. J. (2001) Virology 279, 371-374
25. Dimitrov, D. S. (2004) Nat. Rev. Microbiol. 2, 109-122
26. Xiao, X., and Dimitrov, D. S. (2004) Cell. Mol. Life Sci. 61, 2428-2430
27. Tsai, J. C., Zelus, B. D., Holmes, K. V., and Weiss, S. R. (2003) J. Virol. 77, 841-850
28. Kubo, H., Yamada, Y. K., and Taguchi, F. (1994) J. Virol. 68, 5403-5410
29. Wong, S. K., Li, W., Moore, M. J., Choe, H., and Farzan, M. (2004) J. Biol. Chem. 279, 3197-3201
30. Bonavia, A., Zelus, B. D., Wentworth, D. E., Talbot, P. J., and Holmes, K. V. (2003) J. Virol. 77, 2530-2538
31. Turk, V., Turk, B., and Turk, D. (2001) EMBO J. 20, 4629-4633
32. Golden, J. W., Bahe, J. A., Lucas, W. T., Nibert, M. L., and Schiff, L. A. (2004) J. Biol. Chem. 279, 8547-8557
33. Golden, J. W., Linke, J., Schmechel, S., Thoemke, K., and Schiff, L. A. (2002) J. Virol. 76, 7430-7443
34. Ebert, D. H., Deussing, J., Peters, C., and Dermody, T. S. (2002) J. Biol. Chem. 277, 24609-24617
35. Jane-Valbuena, J., Breun, L. A., Schiff, L. A., and Nibert, M. L. (2002) J. Virol. 76, 5184-5197
36. Baer, G. S., Ebert, D. H., Chung, C. J., Erickson, A. H., and Dermody, T. S. (1999) J. Virol. 73, 9532-9543
37. Chandran, K., Parker, J. S., Ehrlich, M., Kirchhausen, T., and Nibert, M. L. (2003) J. Virol. 77, 13361-13375
38. Odegard, A. L., Chandran, K., Liemann, S., Harrison, S. C., and Nibert, M. L. (2003) J. Virol. 77, 5389-5400
39. Chandran, K., Farsetta, D. L., and Nibert, M. L. (2002) J. Virol. 76, 9920-9933
40. Sturzenbecker, L. J., Nibert, M., Furlong, D., and Fields, B. N. (1987) J. Virol. 61, 2351-2361
41. Chandran, K., Sullivan, N. J., Felbor, U., Whelan, S. P., and Cunningham, J. M. (2005) Science 308, 1643-1645
42. Hsieh, C. S., deRoos, P., Honey, K., Beers, C., and Rudensky, A. Y. (2002) J. Immunol. 168, 2618-2625
43. Holmes, K. V., Dveksler, G., Gagneten, S., Yeager, C., Lin, S. H., Beauchemin, N., Look, A. T., Ashmun, R., and Dieffenbach, C. (1993) Adv. Exp. Med. Biol. 342, 261-266
44. Mirzabekov, T., Bannert, N., Farzan, M., Hofmann, W., Kolchinsky, P., Wu, L., Wyatt, R., and Sodroski, J. (1999) J. Biol. Chem. 274, 28745-28750
45. Moore, M. J., Dorfman, T., Li, W., Wong, S. K., Li, Y., Kuhn, J. H., Coderre, J., Vasilieva, N., Han, Z., Greenough, T. C., Farzan, M., and Choe, H. (2004) J. Virol. 78, 10628-10635
46. Simmons, G., Reeves, J. D., Rennekamp, A. J., Amberg, S. M., Piefer, A. J., and Bates, P. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 4240-4245
47. Wei, B. L., Denton, P. W., O'Neill, E., Luo, T., Foster, J. L., and Garcia, J. V. (2005) J. Virol. 79, 5705-5712
48. Urbich, C., Heeschen, C., Aicher, A., Sasaki, K., Bruhl, T., Farhadi, M. R., Vajkoczy, P., Hofmann, W. K., Peters, C., Pennacchio, L. A., Abolmaali, N. D., Chavakis, E., Reinheckel, T., Zeiher, A. M., and Dimmeler, S. (2005) Nat. Med. 11, 206-213
49. To, K. F., and Lo, A. W. (2004) J. Pathol. 203, 740-743