-
1
-
-
70349840435
-
DNA damage responses in skin biology-implications in tumor prevention and aging acceleration
-
Nakanishi M, Niida H, Murakami H, Shima-da M: DNA damage responses in skin biology-implications in tumor prevention and aging acceleration. J Dermatol Sci 2009; 56: 76-81.
-
(2009)
J Dermatol Sci
, vol.56
, pp. 76-81
-
-
Nakanishi, M.1
Niida, H.2
Murakami, H.3
Shima-Da, M.4
-
2
-
-
66149173551
-
Aging and cancer cell biology, 2009
-
Campisi J, Yaswen P: Aging and cancer cell biology, 2009. Aging Cell 2009; 8:221-225.
-
(2009)
Aging Cell
, vol.8
, pp. 221-225
-
-
Campisi, J.1
Yaswen, P.2
-
3
-
-
41549136422
-
Paths of convergence: Sirtu-ins in aging and neurodegeneration
-
Gan L, Mucke L: Paths of convergence: sirtu-ins in aging and neurodegeneration. Neuron 2008; 58: 10-14.
-
(2008)
Neuron
, vol.58
, pp. 10-14
-
-
Gan, L.1
Mucke, L.2
-
4
-
-
56749156405
-
Sirt1 redistribution on chromatin promotes genomic stability but alters gene expression during aging
-
Oberdoerffer P, Michan S, McVay M, Mosto-slavsky R, Vann J, Park SK, Hartlerode A, Stegmu ller J, Ha fner A, L oerch P, Wrig ht SM, Mills KD, Bonni A, Yankner BA, Scully R, Prolla TA, Alt FW, Sinclair DA: Sirt1 redistribution on chromatin promotes genomic stability but alters gene expression during aging. Cell 2008; 135:907-918.
-
(2008)
Cell
, vol.135
, pp. 907-918
-
-
Oberdoerffer, P.1
Michan, S.2
McVay, M.3
Mosto-Slavsky, R.4
Vann, J.5
Park, S.K.6
Hartlerode, A.7
Stegmuller, J.8
Hafner, A.9
Loerch, P.10
Wright, S.M.11
Mills, K.D.12
Bonni, A.13
Yankner, B.A.14
Scully, R.15
Prolla, T.A.16
Alt, F.W.17
Sinclair, D.A.18
-
5
-
-
0036261707
-
Sensing and repairing DNA double-strand breaks
-
Jackson SP: Sensing and repairing DNA double-strand breaks. Carcinogenesis 2002; 23: 687-696.
-
(2002)
Carcinogenesis
, vol.23
, pp. 687-696
-
-
Jackson, S.P.1
-
6
-
-
36248956174
-
Signaling mechanisms involved in the response to genotoxic stress and regulating life span
-
Niedernhofer LJ, Robbins PD: Signaling mechanisms involved in the response to genotoxic stress and regulating life span. Int J Biochem Cell Biol 2008; 40:176-180.
-
(2008)
Int J Biochem Cell Biol
, vol.40
, pp. 176-180
-
-
Niedernhofer, L.J.1
Robbins, P.D.2
-
7
-
-
34848927457
-
Effects of resveratrol on lifes-pan in Drosophila melanogaster and Cae-norhabditis elegans
-
Bass TM, Weinkove D, Houthoofd K, Gems D, Partridge L: Effects of resveratrol on lifes-pan in Drosophila melanogaster and Cae-norhabditis elegans. Mech Ageing Dev 2007; 128:546-552.
-
(2007)
Mech Ageing Dev
, vol.128
, pp. 546-552
-
-
Bass, T.M.1
Weinkove, D.2
Houthoofd, K.3
Gems, D.4
Partridge, L.5
-
8
-
-
0034626747
-
Genetic pathways t hat regu late ageing i n model orga nisms
-
Guarente L, Kenyon C: Genetic pathways t hat regu late ageing i n model orga nisms. Nature 2000; 408:255-262.
-
(2000)
Nature
, vol.408
, pp. 255-262
-
-
Guarente, L.1
Kenyon, C.2
-
9
-
-
67949102053
-
Recent progress in the biology and physiology of sir-tuins
-
Finkel T, Deng CX, Mostoslavsky R: Recent progress in the biology and physiology of sir-tuins. Nature 2009; 460: 587-591.
-
(2009)
Nature
, vol.460
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
10
-
-
0033887456
-
Phylogenetic classification of pro-karyotic and eukaryotic Sir2-like proteins
-
Frye RA: Phylogenetic classification of pro-karyotic and eukaryotic Sir2-like proteins. Biochem Biophys Res Commun 200 0; 273: 793-798.
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 793-798
-
-
Frye, R.A.1
-
11
-
-
77949887506
-
Mammalian sirtu-ins: Biological insights and disease relevance
-
Haigis MC, Sinclair DA: Mammalian sirtu-ins: biological insights and disease relevance. Annu Rev Pathol 2010; 5:253-295.
-
(2010)
Annu Rev Pathol
, vol.5
, pp. 253-295
-
-
Haigis, M.C.1
Sinclair, D.A.2
-
12
-
-
33751113602
-
Mammalian sirtu-ins-emerging roles in physiology, aging, and calorie restriction
-
Haigis MC, Guarente LP: Mammalian sirtu-ins-emerging roles in physiology, aging, and calorie restriction. Genes Dev 2006; 20: 2913-2921.
-
(2006)
Genes Dev
, vol.20
, pp. 2913-2921
-
-
Haigis, M.C.1
Guarente, L.P.2
-
13
-
-
3943054839
-
The Sir2 family of protein deacetylases
-
Blander G, Guarente L: The Sir2 family of protein deacetylases. Annu Rev Biochem 2004; 73: 417-435.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 417-435
-
-
Blander, G.1
Guarente, L.2
-
14
-
-
2942564591
-
Sirtuins: Sir2-related NAD-dependent protein deacetylases
-
North BJ, Verdin E: Sirtuins: Sir2-related NAD-dependent protein deacetylases. Genome Biol 2004; 5:224.
-
(2004)
Genome Biol
, vol.5
, pp. 224
-
-
North, B.J.1
Verdin, E.2
-
15
-
-
4944245398
-
Human SIRT1 interacts with histone H1 and promotes formation of facultative heterochro-matin
-
Vaquero A, Scher M, Lee D, Erdjument-Bro-mage H, Tempst P, Reinberg D: Human SIRT1 interacts with histone H1 and promotes formation of facultative heterochro-matin. Mol Cell 2004; 16:93-105.
-
(2004)
Mol Cell
, vol.16
, pp. 93-105
-
-
Vaquero, A.1
Scher, M.2
Lee, D.3
Erdjument-Bro-Mage, H.4
Tempst, P.5
Reinberg, D.6
-
16
-
-
31044445366
-
Genomic instability and aging-like phenotype in the absence of mammalian SIRT6
-
Mostoslavsky R, Chua KF, Lombard DB, Pang WW, Fischer MR, Gellon L, Liu P, Mo-stoslavsky G, Franco S, Murphy MM, Mills KD, Patel P, Hsu JT, Hong AL, Ford E, Cheng HL, Kennedy C, Nunez N, Bronson R, Frendewey D, Auerbach W, Valenzuela D, Karow M, Hottiger MO, Hursting S, Barrett JC, Guarente L, Mulligan R, Demple B, Yan-copoulos GD, Alt FW: Genomic instability and aging-like phenotype in the absence of mammalian SIRT6. Cell 2006; 124:315-329.
-
(2006)
Cell
, vol.124
, pp. 315-329
-
-
Mostoslavsky, R.1
Chua, K.F.2
Lombard, D.B.3
Pang, W.W.4
Fischer, M.R.5
Gellon, L.6
Liu, P.7
Mo-Stoslavsky, G.8
Franco, S.9
Murphy, M.M.10
Mills, K.D.11
Patel, P.12
Hsu, J.T.13
Hong, A.L.14
Ford, E.15
Cheng, H.L.16
Kennedy, C.17
Nunez, N.18
Bronson, R.19
Frendewey, D.20
Auerbach, W.21
Valenzuela, D.22
Karow, M.23
Hottiger, M.O.24
Hursting, S.25
Barrett, J.C.26
Guarente, L.27
Mulligan, R.28
Demple, B.29
Yan-Copoulos, G.D.30
Alt, F.W.31
more..
-
17
-
-
12144290563
-
Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
-
Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, Lin Y, Tran H, Ross SE, Mosto-slavsky R, Cohen HY, Hu LS, Cheng HL, Je-drychowski MP, Gygi SP, Sinclair DA, Alt FW, Greenberg ME: Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004; 303: 2011-2015.
-
(2004)
Science
, vol.303
, pp. 2011-2015
-
-
Brunet, A.1
Sweeney, L.B.2
Sturgill, J.F.3
Chua, K.F.4
Greer, P.L.5
Lin, Y.6
Tran, H.7
Ross, S.E.8
Mosto-Slavsky, R.9
Cohen, H.Y.10
Hu, L.S.11
Cheng, H.L.12
Je-Drychowski, M.P.13
Gygi, S.P.14
Sinclair, D.A.15
Alt, F.W.16
Greenberg, M.E.17
-
18
-
-
4143050290
-
The interaction between FOXO and SIRT1: Tipping the balance towards survival
-
Giannakou ME, Partridge L: The interaction between FOXO and SIRT1: tipping the balance towards survival. Trends Cell Biol 2004; 14: 408-412.
-
(2004)
Trends Cell Biol
, vol.14
, pp. 408-412
-
-
Giannakou, M.E.1
Partridge, L.2
-
19
-
-
34548471739
-
Cytoplasm-localized SIRT1 enhances apop-tosis
-
Jin Q, Yan T, Ge X, Sun C, Shi X, Zhai Q: Cytoplasm-localized SIRT1 enhances apop-tosis. J Cell Physiol 2007; 213:88-97.
-
(2007)
J Cell Physiol
, vol.213
, pp. 88-97
-
-
Jin, Q.1
Yan, T.2
Ge, X.3
Sun, C.4
Shi, X.5
Zhai, Q.6
-
20
-
-
54349106390
-
C. el-egans SIR-2.1 translocation is linked to a pro-apoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis
-
Greiss S, Hall J, Ahmed S, Gartner A: C. el-egans SIR-2.1 translocation is linked to a pro-apoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis. Genes Dev 2008; 22:2831-2842.
-
(2008)
Genes Dev
, vol.22
, pp. 2831-2842
-
-
Greiss, S.1
Hall, J.2
Ahmed, S.3
Gartner, A.4
-
21
-
-
68349084590
-
Sir t1 i n-volvement in rd10 mouse retinal degeneration
-
Jaliffa C, Ameqrane I, Dansault A, Leemput J, Vieira V, Lacassagne E, Provost A, Bigot K, Masson C, Menasche M, Abitbol M: Sir t1 i n-volvement in rd10 mouse retinal degeneration. Invest Ophthalmol Vis Sci 2009; 50: 3562-3572.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 3562-3572
-
-
Jaliffa, C.1
Ameqrane, I.2
Dansault, A.3
Leemput, J.4
Vieira, V.5
Lacassagne, E.6
Provost, A.7
Bigot, K.8
Masson, C.9
Menasche, M.10
Abitbol, M.11
-
22
-
-
0141814680
-
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
-
Cheng HL, Mostoslavsky R, Saito S, Manis JP, Gu Y, Patel P, Bronson R, Appella E, Alt FW, Chua KF: Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci USA 2003; 100:10794-10799.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 10794-10799
-
-
Cheng, H.L.1
Mostoslavsky, R.2
Saito, S.3
Manis, J.P.4
Gu, Y.5
Patel, P.6
Bronson, R.7
Appella, E.8
Alt, F.W.9
Chua, K.F.10
-
23
-
-
72449178334
-
Division and apoptosis of E2f-deficient retinal progenitors
-
Chen D, Pacal M, Wenzel P, Knoepfler PS, Leone G, Bremner R: Division and apoptosis of E2f-deficient retinal progenitors. Nature 2009; 462:925-929.
-
(2009)
Nature
, vol.462
, pp. 925-929
-
-
Chen, D.1
Pacal, M.2
Wenzel, P.3
Knoepfler, P.S.4
Leone, G.5
Bremner, R.6
-
24
-
-
34648837170
-
SIRT1 activation confers neuro-protection in experimental optic neuritis
-
Shindler KS, Ventura E, Rex TS, Elliott P, Rostami A: SIRT1 activation confers neuro-protection in experimental optic neuritis. Invest Ophthalmol Vis Sci 2007; 48:3602-3609.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 3602-3609
-
-
Shindler, K.S.1
Ventura, E.2
Rex, T.S.3
Elliott, P.4
Rostami, A.5
-
25
-
-
4043165678
-
Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
-
Araki T, Sasaki Y, Milbrandt J: Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration. Science 2004; 305: 1010-1013.
-
(2004)
Science
, vol.305
, pp. 1010-1013
-
-
Araki, T.1
Sasaki, Y.2
Milbrandt, J.3
-
26
-
-
69449106145
-
Axonal and cell body protection by nicotinamide adenine dinucle-otide in tumor necrosis factor-induced optic neuropathy
-
Kitaoka Y, Hayashi Y, Kumai T, Takeda H, Munemasa Y, Fujino H, Kitaoka Y, Ueno S, Sadun AA, Lam TT: Axonal and cell body protection by nicotinamide adenine dinucle-otide in tumor necrosis factor-induced optic neuropathy. J Neuropathol Exp Neurol 2009; 68:915-927.
-
(2009)
J Neuropathol Exp Neurol
, vol.68
, pp. 915-927
-
-
Kitaoka, Y.1
Hayashi, Y.2
Kumai, T.3
Takeda, H.4
Munemasa, Y.5
Fujino, H.6
Kitaoka, Y.7
Ueno, S.8
Sadun, A.A.9
Lam, T.T.10
-
27
-
-
67649946223
-
Prevention of ocular inflammation in endotoxin-induced uveitis with res-veratrol by inhibiting oxidative damage and nuclear factor-kappaB activation
-
Kubota S, Kurihara T, Mochimaru H, Sato-f u k a S, Nod a K, O z awa Y, Oi k e Y, Ishid a S, Tsubota K: Prevention of ocular inflammation in endotoxin-induced uveitis with res-veratrol by inhibiting oxidative damage and nuclear factor-kappaB activation. Invest Ophthalmol Vis Sci 2009; 50: 3512-3519.
-
(2009)
Invest Ophthalmol Vis Sci
, vol.50
, pp. 3512-3519
-
-
Kubota, S.1
Kurihara, T.2
Mochimaru, H.3
Sato-Fuka, S.4
Noda, K.5
Ozawa, Y.6
Oike, Y.7
Ishida, S.8
Tsubota, K.9
-
28
-
-
77956926306
-
Age-related increase in mitochondrial DNA damage and loss of DNA repair capacity in the neural retina
-
E-pub ahead of print
-
Wang AL, Lukas TJ, Yuan M, Neufeld AH: Age-related increase in mitochondrial DNA damage and loss of DNA repair capacity in the neural retina. Neurobiol Aging, E-pub ahead of print.
-
Neurobiol Aging
-
-
Wang, A.L.1
Lukas, T.J.2
Yuan, M.3
Neufeld, A.H.4
|