Jeffamine derivatized tentagel beads and poly(dimethylsiloxane) microbead cassettes for ultrahigh-throughput in situ releasable solution-phase cell-based screening of one-bead-one-compound combinatorial small molecule libraries

Journal of Combinatorial Chemistry

Volumn 12, Issue 5, 2010, Pages 700-712

  Townsend, Jared B ^a   Shaheen, Farzana ^a   Liu, Ruiwu ^a   Lam, Kit S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINE; ANTINEOPLASTIC AGENT; BAYSILON; DIMETICONE; POLYSTYRENE DERIVATIVE; TENTAGEL RESIN;

ARTICLE; CELL SURVIVAL; CHEMICAL STRUCTURE; CHEMISTRY; COMBINATORIAL CHEMISTRY; DOSE RESPONSE; DRUG EFFECT; DRUG SCREENING; HIGH THROUGHPUT SCREENING; HUMAN; LEUKEMIA CELL LINE; SOLUTION AND SOLUBILITY; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE;

AMINES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; COMBINATORIAL CHEMISTRY TECHNIQUES; DIMETHYLPOLYSILOXANES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG SCREENING ASSAYS, ANTITUMOR; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; JURKAT CELLS; MOLECULAR STRUCTURE; POLYSTYRENES; SOLUTIONS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 77956522287     PISSN: 15204766     EISSN: 15204774     Source Type: Journal    
DOI: 10.1021/cc100083f     Document Type: Article

References (57)

1. Lam, K. S., Salmon, S. E., Hersh, E. M., Hruby, V. J., Kazmierski, W. M., and Knapp, R. J. Nature 1991, 354 (6348) 82-84
2. Lam, K. S., Lebl, M., Krchnak, V., Lake, D. F., Smith, J., Wade, S., Ferguson, R., Ackerman-Berrier, M., and Wertman, K. In Peptides: Chemistry, Structure and Biology, Proceedings of the 12th American Peptide Symposium; Hodges, R. S. and Smith, J. A., Eds.; ESCOM: Leiden, 1994; pp 1003 - 1004.
3. Lam, K. S., Lebl, M., Wade, S., Stierandova, A., Khattri, P. S., Collins, N., and Hruby, V. J. In Peptides: Chemistry, Structure and Biology, Proceedings of the 13th American Peptide Symposium; ESCOM: Leiden, 1994; pp 1005 - 1006.
4. Aina, O. H., Marik, J., Liu, R., Lau, D. H., and Lam, K. S. Mol. Cancer Ther. 2005, 4, 806-813
5. Aina, O. H., Sroka, T. C., Chen, M., and Lam, K. S. Biopolymers 2002, 66, 184-199
6. Benito, J. M. and Meldal, M. QSAR Comb. Sci. 2004, 23, 117-129
7. Lau, D. H., Guo, L., Liu, R., Song, A., Shao, C., and Lam, K. S. Biotechnol. Lett. 2002, 24, 497-500
8. McBride, J. D., Freeman, H. N. M., and Leatherbarrow, R. J. Eur. J. Biochem. 1999, 266, 403-412
9. McBride, J. D., Freeman, N., Domingo, G. J., and Leatherbarrow, R. J. J. Mol. Biol. 1996, 259, 819-827
10. Mikawa, M., Wang, H., and Guo, L. Mol. Cancer Ther 2004, 3, 1329-1334
11. Wittmann, V. and Seeberger, S. Angew. Chem., Int. Ed. 2000, 39, 4348-4352
12. Liu, B., Alluri, P. G., Yu, P., and Kodadek, T. J. Am. Chem. Soc. 2005, 127, 8254-8255
13. Alluri, P. G., Reddy, M. M., Bachhawat-Sikder, K., Olivos, H. J., and Kodadek, T. J. Am. Chem. Soc. 2003, 125, 13995-14004
14. Reddy, M. M., Bachhawat-Sikder, K., and Kodadek, T. Chem. Biol. 2004, 11, 1127-1137
15. Appell, K. C., Chung, T. D. Y., Ohlmeyer, M. J. H., Sigal, N. H., Baldwin, J. J., and Chelsky, D. J. Biomol. Screening 1996, 1, 27-31
16. Baldwin, J. J., Burbaum, J. J., Henderson, I., and Ohlmeyer, M. H. J. J. Am. Chem. Soc. 1995, 117, 5588-5589
17. Lam, K. S., Liu, R., Miyamoto, S., Lehman, A. L., and Tuscano, J. M. Acc. Chem. Res. 2003, 36, 370-377
18. Lo, M. M. C., Neumann, C. S., Nagayama, S., Perlstein, E. O., and Schreiber, S. L. J. Am. Chem. Soc. 2004, 126, 16077-16086
19. Stavenger, R. A. and Schreiber, S. L. Angew. Chem., Int. Ed. 2001, 40, 3417-3421
20. Al-Obeidi, F. A. and Lam, K. S. Oncogene 2000, 19 (49) 5690-5701
21. Kamath, J. R., Liu, R., Enstrom, A. M., Lou, Q., and Lam, K. S. J. Pept. Res. 2003, 62 (6) 260-268
22. Ramdas, L., Bunnin, B. A., Plunkett, M. J., Sun, G., Ellman, J., Gallick, G., and Budde, R. J. Arch. Biochem. Biophys. 1999, 368 (2) 394-400
23. Lam, K. S., Lebl, M., and Krchnak, V. Chem. Rev. 1997, 97 (2) 411-448
24. Meldal, M. Methods (San Diego, CA, U. S.) 1994, 6, 417-424
25. Meldal, M. and Svendsen, I. J. Chem. Soc., Perkin Trans. 1995, 1591-1596
26. Meldal, M., Svendsen, I., Breddam, K., and Auzanneau, F. I. Proc. Natl. Acad. Sci. U.S.A. 1994, 9, 3314-3318
27. Abato, P., Conroy, J. L., and Seto, C. T. J. Med. Chem. 1999, 42 (19) 4001-4009
28. Kick, E. K., Roe, D. C., Skillman, A. G., Liu, G., Ewing, T. J., Sun, Y., Kuntz, I. D., and Ellman, J. A. Chem. Biol. 1997, 4 (4) 297-307
29. Chirayil, S., Chirayil, R., and Luebke, K. J. Nucleic Acids Res. 2009, 37 (16) 5486-5497
30. Peng, L., Liu, R., Marik, J., Wang, X., Takada, Y., and Lam, K. S. Nat. Chem. Biol. 2006, 2 (7) 381-389
31. Lam, K. S., Lou, Q., Zhao, Z. G., Smith, J., Chen, M. L., Pleshko, E., and Salmon, S. E. Biomed. Pept. Proteins Nucleic Acids 1995, 1 (3) 205-210
32. Maverakis, E., Menezes, J. S., Ametani, A., Han, M., Stevens, D. B., He, Y., Wang, Y., Ono, Y., Miyamura, Y., Lam, K. S., Ward, E. S., and Sercarz, E. E. Proc. Natl. Acad. Sci. U.S.A. 2010, 107 (6) 2550-2555
33. Liu, R., Enstrom, A. M., and Lam, K. S. Exp. Hematol. 2003, 31 (1) 11-30
34. Righetti, P. G., Boschetti, E., Lomas, L., and Citterio, A. Proteomics 2006, 6 (14) 3980-3992
35. Guerrier, L., Thulasiraman, V., Castagna, A., Fortis, F., Lin, S., Lomas, L., Righetti, P. G., and Boschetti, E. J. Chromatogr., B: Anal. Technol. Biomed. Life Sci. 2006, 833 (1) 33-40
36. Gregori, L., Gurgel, P. V., Lathrop, J. T., Edwardson, P., Lambert, B. C., Carbonell, R. G., Burton, S. J., Hammond, D. J., and Rohwer, R. G. Lancet 2006, 368 (9554) 2226-2230
37. Tozzi, C., Anfossi, L., Baggiani, C., Giovannoli, C., and Giraudi, G. Anal. Bioanal. Chem. 2003, 375, 994-999
38. Amatschek, K., Necina, R., and Hahn, R. J. High Resolut. Chromatogr. 2000, 23, 47-58
39. Kaufman, D. B., Hentsch, M. E., and Baumbach, G. A. Biotechnol. Bioeng. 2002, 77, 278-289
40. Liu, R., Marik, J., and Lam, K. S. J. Am. Chem. Soc. 2002, 124, 7678-7680
41. Liu, R., Wang, X., Song, A., Bao, T., and Lam, K. S. QSAR Comb. Sci. 2005, 24 (10) 1127-1140
42. Salmon, S. E., Lam, K. S., Lebl, M., Kandola, A., Khattri, P. S., Wade, S., Patek, M., Kocis, P., Krchnak, V., and Thorpe, D. Proc. Natl. Acad. Sci. U.S.A. 1993, 90 (24) 11708-11712
43. Lebl, M., Patek, M., Kocis, P., Krchnak, V., Hruby, V. J., Salmon, S. E., and Lam, K. S. Int. J. Pept. Protein Res. 1993, 41 (2) 201-203
44. Baek, H. G., Liu, R., and Lam, K. S. J. Comb. Chem. 2009, 11 (1) 91-102
45. Evans, B., Pipe, A., Clark, L., and Banks, M. Bioorg. Med. Chem. Lett. 2001, 11 (10) 1297-1300
46. Hiemstra, H. S., Benckhuijsen, W. E., Amons, R., Rapp, W., and Drijfhout, J. W. J. Pept. Sci. 1998, 4 (4) 282-288
47. Silen, J. L., Lu, A. T., Solas, D. W., Gore, M. A., MacLean, D., Shah, N. H., Coffin, J. M., Bhinderwala, N. S., Wang, Y., Tsutsui, K. T., Look, G. C., Campbell, D. A., Hale, R. L., Navre, M., and DeLuca-Flaherty, C. R. Antimicrob. Agents Chemother. 1998, 42 (6) 1447-1453
48. Jayawickreme, C. K., Sauls, H., Bolio, N., Ruan, J., Moyer, M., Burkhart, W., Marron, B., Rimele, T., and Shaffer, J. J. Pharmacol. Toxicol. Methods 1999, 42 (4) 189-197
49. Quillan, J. M., Jayawickreme, C. K., and Lerner, M. R. Proc. Natl. Acad. Sci. U.S.A. 1995, 92 (7) 2894-2898
50. Iuga, A. O., Reddy, V. B., and Lerner, E. A. Peptides 2005, 26 (11) 2124-2128
51. Salmon, S. E., Liu-Stevens, R. H., Zhao, Y., Lebl, M., Krchnak, V., Wertman, K., Sepetov, N., and Lam, K. S. Mol. Diversity 1996, 2 (1-2) 57-63
52. Rissler, K. J. Chromatogr., A 1994, 667 (1-2) 167-174
53. Rissler, K. J. Chromatogr., A 1996, 742 (1-2) 1-54
54. Kim, H., Cho, J. K., Chung, W. J., and Lee, Y. S. Org. Lett. 2004, 6 (19) 3273-3276
55. Noguchi, H., Matsushita, M., Okitsu, T., Moriwaki, A., Tomizawa, K., Kang, S., Li, S. T., Kobayashi, N., Matsumoto, S., Tanaka, K., Tanaka, N., and Matsui, H. Nat. Med. 2004, 10 (3) 305-309
56. Garaud, M. and Pei, D. J. Am. Chem. Soc. 2007, 129 (17) 5366-5367
57. Joo, S. H., Xiao, Q., Ling, Y., Gopishetty, B., and Pei, D. J. Am. Chem. Soc. 2006, 128 (39) 13000-13009