Molecular mimics can induce a nonautoaggressive repertoire that preempts induction of autoimmunity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 107, Issue 6, 2010, Pages 2550-2555

  Maverakis, Emanual ^a,b,c   Menezes, Juscilene S ^a,d   Ametani, Akio ^a,d   Han, Mei ^e   Stevens, David B ^a   He, Yong ^b   Wang, Yan ^b   Ono, Yoko ^b   Miyamura, Yoshinori ^b   Lam, Kit S ^b   Ward, E Sally ^e   Sercarz, Eli E ^a,d  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d TORREY PINES INSTITUTE FOR MOLECULAR STUDIES   (United States)

^e UNIVERSITY OF TEXAS AT DALLAS   (United States)

Author keywords

Autoimmune; Driver clones; Experimental autoimmune encephalomyelitis; Molecular mimicry; Multiple sclerosis

Indexed keywords

ALTERED PEPTIDE LIGAND; ENCEPHALITOGENIC PROTEIN; FREUND ADJUVANT; GAMMA INTERFERON; LIGAND; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ALLERGIC ENCEPHALOMYELITIS; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOIMMUNITY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HYBRIDOMA; IN VITRO STUDY; MOLECULAR MIMICRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION;

AMINO ACID SEQUENCE; ANIMALS; AUTOIMMUNITY; CELL PROLIFERATION; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; FLOW CYTOMETRY; IMMUNIZATION; LYMPH NODES; MICE; OLIGOPEPTIDES; RECEPTORS, ANTIGEN, T-CELL; SPLEEN; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES;

EID: 77249092530     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0914508107     Document Type: Article

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