Microarray-assisted high-throughput identification of a cell-permeable small-molecule binder of 14-3-3 proteins

Angewandte Chemie - International Edition

Volumn 49, Issue 37, 2010, Pages 6528-6532

  Wu, Hao ^a   Ge, Jingyan ^a   Yao, Shao Q ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Combinatorial chemistry; Fragment based screening; Microarrays; Protein protein interactions; Proteins

Indexed keywords

14-3-3 PROTEINS; CELL-PERMEABLE; COMBINATORIAL CHEMISTRY; FRAGMENT-BASED SCREENING; HIGH-THROUGHPUT; IN-CELL; IN-VITRO; PROTEIN INTERACTION; PROTEIN-PROTEIN INTERACTIONS; SMALL MOLECULES;

BINDERS; BIOASSAY; BIOCHIPS; MOLECULES;

PROTEINS;

ISOPROTEIN; PROTEIN 14 3 3;

ANIMAL; ARTICLE; CELL LINE; CHEMICAL STRUCTURE; GENETICS; HIGH THROUGHPUT SCREENING; HUMAN; METABOLISM; METHODOLOGY; PROTEIN MICROARRAY;

14-3-3 PROTEINS; ANIMALS; CELL LINE; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; MOLECULAR STRUCTURE; PROTEIN ARRAY ANALYSIS; PROTEIN ISOFORMS;

EID: 77956509771     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201003257     Document Type: Article

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