Antiproliferative effect of Tualang honey on oral squamous cell carcinoma and osteosarcoma cell lines

BMC Complementary and Alternative Medicine

Volumn 10, Issue , 2010, Pages

  Ghashm, Abdulmlik A ^a   Othman, Nor H ^b   Khattak, Mohammed N ^b   Ismail, Noorliza M ^a   Saini, Rajan ^a  

^a SCHOOL OF HEALTH SCIENCES   (Malaysia)

^b SCHOOL OF MEDICAL SCIENCES   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HERBACEOUS AGENT;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL COUNT; CELL PROLIFERATION; CELL STRUCTURE; CELL VIABILITY; CHROMATIN CONDENSATION; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HONEY; HUMAN; HUMAN CELL; IC 50; MICROSCOPY; MOUTH CARCINOMA; OPTICAL DENSITY; OSTEOSARCOMA; OSTEOSARCOMA CELL; SQUAMOUS CELL CARCINOMA; TUALANG HONEY; APITHERAPY; BONE TUMOR; CELL SURVIVAL; MOUTH TUMOR; TUMOR CELL LINE;

APITHERAPY; APOPTOSIS; BONE NEOPLASMS; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; FLOW CYTOMETRY; HONEY; HUMANS; MOUTH NEOPLASMS; OSTEOSARCOMA;

EID: 77956461244     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-10-49     Document Type: Article

References (48)

1. WHO Global data on incidence of oral cancer. Oral health programme 2005, Geneva, WHO.
2. Moore SR, Johnson NW, Pierce AM, Wilson DF. The epidemiology of mouth cancer: a review of global incidence. Oral Dis 2000, 6(2):65-74. 10.1111/j.1601-0825.2000.tb00104.x, 10702782.
3. La Vecchia C, Tavani A, Franceschi S, Levi F, Corrao G, Negri E. Epidemiology and prevention of oral cancer. Oral Oncol 1997, 33(5):302-312. 10.1016/S1368-8375(97)00029-8, 9415327.
4. Chen WL, Feng HJ, Li HG. Expression and significance of hypoxemia-inducible factor-1alpha in osteosarcoma of the jaws. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2008, 106(2):254-257. 10.1016/j.tripleo.2008.01.029, 18554951.
5. Day TA, Davis BK, Gillespie MB, Joe JK, Kibbey M, Martin-Harris B, Neville B, Richardson MS, Rosenzweig S, Sharma AK, et al. Oral cancer treatment. Curr Treat Options Oncol 2003, 4(1):27-41. 10.1007/s11864-003-0029-4, 12525277.
6. Bramer JA, van Linge JH, Grimer RJ, Scholten RJ. Prognostic factors in localized extremity osteosarcoma: a systematic review. Eur J Surg Oncol 2009, 35(10):1030-1036.
7. Kim MJ, Lee JH, Kim YK, Myoung H, Yun PY. The role of tamoxifen in combination with cisplatin on oral squamous cell carcinoma cell lines. Cancer Lett 2007, 245(1-2):284-292. 10.1016/j.canlet.2006.01.017, 16513256.
8. Tong D, Poot M, Hu D, Oda D. 5-Fluorouracil-induced apoptosis in cultured oral cancer cells. Oral Oncol 2000, 36(2):236-241. 10.1016/S1368-8375(99)00079-2, 10745178.
9. Wu WC, Hsiao JR, Lian YY, Lin CY, Huang BM. The apoptotic effect of cordycepin on human OEC-M1 oral cancer cell line. Cancer Chemother Pharmacol 2007, 60(1):103-111. 10.1007/s00280-006-0354-y, 17031645.
10. Zhang DY, Wu J, Ye F, Xue L, Jiang S, Yi J, Zhang W, Wei H, Sung M, Wang W, et al. Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. Cancer Res 2003, 63(14):4037-4043.
11. Haghiac M, Walle T. Quercetin induces necrosis and apoptosis in SCC-9 oral cancer cells. Nutr Cancer 2005, 53(2):220-231. 10.1207/s15327914nc5302_11, 16573383.
12. Nam W, Tak J, Ryu JK, Jung M, Yook JI, Kim HJ, Cha IH. Effects of artemisinin and its derivatives on growth inhibition and apoptosis of oral cancer cells. Head Neck 2007, 29(4):335-340. 10.1002/hed.20524, 17163469.
13. Shi SL, Li QF, Liu QR, Xu DH, Tang J, Liang Y, Zhao ZL, Yang LM. Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT). J Cell Biochem 2009, 108(4):926-934. 10.1002/jcb.22324, 19725052.
14. Corbiere C, Liagre B, Bianchi A, Bordji K, Dauca M, Netter P, Beneytout JL. Different contribution of apoptosis to the antiproliferative effects of diosgenin and other plant steroids, hecogenin and tigogenin, on human 1547 osteosarcoma cells. Int J Oncol 2003, 22(4):899-905.
15. Wang J, Yin JQ, Shen JN, Jia Q, Huang G, Jin S, Zou CY. In vitro screening of 32 traditional Chinese herbal extracts against U2OS human osteosarcoma cells. Nan Fang Yi Ke Da Xue Xue Bao 2006, 26(9):1293-1296.
16. Irish J, Carter DA, Blair SE, Heard TA. Antibacterial activity of honey from the Australian stingless bee Trigona carbonaria. Int J Antimicrob Agents 2008, 32(1):89-90. 10.1016/j.ijantimicag.2008.02.012, 18495440.
17. Temaru E, Shimura S, Amano K, Karasawa T. Antibacterial activity of honey from stingless honeybees (Hymenoptera; Apidae; Meliponinae). Pol J Microbiol 2007, 56(4):281-285.
18. Gheldof N, Engeseth NJ. Antioxidant capacity of honeys from various floral sources based on the determination of oxygen radical absorbance capacity and inhibition of in vitro lipoprotein oxidation in human serum samples. J Agric Food Chem 2002, 50(10):3050-3055. 10.1021/jf0114637, 11982440.
19. Estevinho L, Pereira AP, Moreira L, Dias LG, Pereira E. Antioxidant and antimicrobial effects of phenolic compounds extracts of Northeast Portugal honey. Food Chem Toxicol 2008, 46(12):3774-3779. 10.1016/j.fct.2008.09.062, 18940227.
20. Wang XH, Andrae L, Engeseth NJ. Antimutagenic effect of various honeys and sugars against Trp-p-1. J Agric Food Chem 2002, 50(23):6923-6928. 10.1021/jf025641n, 12405798.
21. Swellam T, Miyanaga N, Onozawa M, Hattori K, Kawai K, Shimazui T, Akaza H. Antineoplastic activity of honey in an experimental bladder cancer implantation model: in vivo and in vitro studies. Int J Urol 2003, 10(4):213-219. 10.1046/j.0919-8172.2003.00602.x, 12657101.
22. Orsolic N, Terzic S, S L, Basic I. Honey-bee products in prevention and/or therapy of murine transplantable tumours. J Sci Food Agric 2005, 85:363-370.
23. Boukraa L, Amara K. Synergistic effect of starch on the antibacterial activity of honey. J Med Food 2008, 11(1):195-198. 10.1089/jmf.2007.502, 18361758.
24. Beretta G, Orioli M, Facino RM. Antioxidant and radical scavenging activity of honey in endothelial cell cultures (EA.hy926). Planta Med 2007, 73(11):1182-1189. 10.1055/s-2007-981598, 17823875.
25. Viuda-Martos M, Ruiz-Navajas Y, Fernandez-Lopez J, Perez-Alvarez JA. Functional properties of honey, propolis, and royal jelly. J Food Sci 2008, 73(9):R117-124. 10.1111/j.1750-3841.2008.00966.x, 19021816.
26. Hegazi AG, Abd El-Hady FK. Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro). Evid Based Complement Alternat Med 2009, 6(1):113-121. 10.1093/ecam/nem071, 2644272, 18955249.
27. Bardy J, Slevin NJ, Mais KL, Molassiotis A. A systematic review of honey uses and its potential value within oncology care. J Clin Nurs 2008, 17(19):2604-2623. 10.1111/j.1365-2702.2008.02304.x, 18808626.
28. Rao CV, Desai D, Rivenson A, Simi B, Amin S, Reddy BS. Chemoprevention of colon carcinogenesis by phenylethyl-3-methylcaffeate. Cancer Res 1995, 55(11):2310-2315.
29. Ghazali FC. Morphological characterization study of Malaysian honey - A VPSEM, EDX randomised attempt. Annals of Microscopy 2009, 9:93-102.
30. Tan HT, Rahman RA, Gan SH, Halim AS, Hassan SA, Sulaiman SA, Kirnpal-Kaur B. The antibacterial properties of Malaysian tualang honey against wound and enteric microorganisms in comparison to manuka honey. BMC Complement Altern Med 2009, 9:34. 10.1186/1472-6882-9-34, 2753561, 19754926.
31. Tumin N, Halim NA, Shahjahan M, Noor Izani NJ, Sattar MA, Khan AH, Mohsin SSJ. Antibacterial activity of local Malaysian honey. Mal J of Pharmaceut Sci 2005, 3(2):1-10.
32. Wang X, Yuan S, Wang J, Lin P, Liu G, Lu Y, Zhang J, Wang W, Wei Y. Anticancer activity of litchi fruit pericarp extract against human breast cancer in vitro and in vivo. Toxicol Appl Pharmacol 2006, 215(2):168-178. 10.1016/j.taap.2006.02.004, 16563451.
33. Allen KL, Molan PC, Reid GM. A survey of the antibacterial activity of some New Zealand honeys. J Pharm Pharmacol 1991, 43(12):817-822.
34. Hsiao JR, Leu SF, Huang BM. Apoptotic mechanism of paclitaxel-induced cell death in human head and neck tumor cell lines. J Oral Pathol Med 2009, 38(2):188-197. 10.1111/j.1600-0714.2008.00732.x, 19200178.
35. Pietra G, Mortarini R, Parmiani G, Anichini A. Phases of apoptosis of melanoma cells, but not of normal melanocytes, differently affect maturation of myeloid dendritic cells. Cancer Res 2001, 61(22):8218-8226.
36. Gomez-Caravaca AM, Gomez-Romero M, Arraez-Roman D, Segura-Carretero A, Fernandez-Gutierrez A. Advances in the analysis of phenolic compounds in products derived from bees. J Pharm Biomed Anal 2006, 41(4):1220-1234. 10.1016/j.jpba.2006.03.002, 16621403.
37. Simon A, Traynor K, Santos K, Blaser G, Bode U, Molan P. Medical honey for wound care--still the 'latest resort'?. Evid Based Complement Alternat Med 2009, 6(2):165-173. 10.1093/ecam/nem175, 2686636, 18955301.
38. Biswal BM, Zakaria A, Ahmad NM. Topical application of honey in the management of radiation mucositis: a preliminary study. Support Care Cancer 2003, 11(4):242-248.
39. Chiba M, Idobata K, Kobayashi N, Sato Y, Muramatsu Y. Use of honey to ease the pain of stomatitis during radiotherapy. Kangogaku Zasshi 1985, 49(2):171-176.
40. English HK, Pack AR, Molan PC. The effects of manuka honey on plaque and gingivitis: a pilot study. J Int Acad Periodontol 2004, 6(2):63-67.
41. Sela M, Maroz D, Gedalia I. Streptococcus mutans in saliva of normal subjects and neck and head irradiated cancer subjects after consumption of honey. J Oral Rehabil 2000, 27(3):269-270. 10.1046/j.1365-2842.2000.00504.x, 10784339.
42. Gribel NV, Pashinskii VG. The antitumor properties of honey. Vopr Onkol 1990, 36(6):704-709.
43. Jaganathan SK, Mandal M. Antiproliferative effects of honey and of its polyphenols: a review. J Biomed Biotechnol 2009, 2009:1-13.
44. Rao CV, Desai D, Simi B, Kulkarni N, Amin S, Reddy BS. Inhibitory effect of caffeic acid esters on azoxymethane-induced biochemical changes and aberrant crypt foci formation in rat colon. Cancer Res 1993, 53(18):4182-4188.
45. Fukuda M, Kobayashi K, Hirono Y, Miyagawa M, Ishida T, Ejiogu EC, Sawai M, Pinkerton KE, Takeuchi M. Jungle Honey Enhances Immune Function and Antitumor Activity. Evid Based Complement Alternat Med 2009, 1-8.
46. Lee HC, Wei YH. Mitochondrial role in life and death of the cell. J Biomed Sci 2000, 7(1):2-15. 10.1007/BF02255913, 10644884.
47. Hengartner MO. The biochemistry of apoptosis. Nature 2000, 407(6805):770-776. 10.1038/35037710, 11048727.
48. Jaganathan SK, Mandal M. Involvement of non-protein thiols, mitochondrial dysfunction, reactive oxygen species and p53 in honey-induced apoptosis. Invest New Drugs 2010, 28(5):624-33. 10.1007/s10637-009-9302-0, 19705065.