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Volumn 5, Issue 4, 2010, Pages

A flanking gene problem leads to the discovery of a Gprc5b splice variant predominantly expressed in C57BL/6J mouse brain and in maturing neurons

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; G PROTEIN COUPLED RECEPTOR; MESSENGER RNA; METABOTROPIC RECEPTOR; PROTEIN GPRC5B; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; GPRC5B PROTEIN, HUMAN; ISOPROTEIN;

EID: 77956398507     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0010351     Document Type: Article
Times cited : (13)

References (44)
  • 1
    • 42149181885 scopus 로고    scopus 로고
    • Structural diversity of G protein-coupled receptors and significance for drug discovery
    • Lagerstrom MC, Schioth HB (2008) Structural diversity of G protein-coupled receptors and significance for drug discovery. Nat Rev Drug Discov 7: 339-357.
    • (2008) Nat Rev Drug Discov , vol.7 , pp. 339-357
    • Lagerstrom, M.C.1    Schioth, H.B.2
  • 2
    • 19244382287 scopus 로고    scopus 로고
    • Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain
    • Brauner-Osborne H, Krogsgaard-Larsen P (2000) Sequence and expression pattern of a novel human orphan G-protein-coupled receptor, GPRC5B, a family C receptor with a short amino-terminal domain. Genomics 65: 121-128.
    • (2000) Genomics , vol.65 , pp. 121-128
    • Brauner-Osborne, H.1    Krogsgaard-Larsen, P.2
  • 3
    • 0034235002 scopus 로고    scopus 로고
    • Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C)
    • Robbins MJ, Michalovich D, Hill J, Calver AR, Medhurst AD, et al. (2000) Molecular cloning and characterization of two novel retinoic acid-inducible orphan G-protein-coupled receptors (GPRC5B and GPRC5C). Genomics 67: 8-18.
    • (2000) Genomics , vol.67 , pp. 8-18
    • Robbins, M.J.1    Michalovich, D.2    Hill, J.3    Calver, A.R.4    Medhurst, A.D.5
  • 4
    • 0029855236 scopus 로고    scopus 로고
    • G protein coupled R7G receptors
    • Strosberg AD (1996) G protein coupled R7G receptors. Cancer Surv 27: 65-83.
    • (1996) Cancer Surv , vol.27 , pp. 65-83
    • Strosberg, A.D.1
  • 5
    • 34249749817 scopus 로고    scopus 로고
    • Retinoic acid-inducible G protein-coupled receptors bind to frizzled receptors and may activate non-canonical Wnt signaling
    • Harada Y, Yokota C, Habas R, Slusarski DC, He X (2007) Retinoic acid-inducible G protein-coupled receptors bind to frizzled receptors and may activate non-canonical Wnt signaling. Biochem Biophys Res Commun 358: 968-975.
    • (2007) Biochem Biophys Res Commun , vol.358 , pp. 968-975
    • Harada, Y.1    Yokota, C.2    Habas, R.3    Slusarski, D.C.4    He, X.5
  • 6
    • 0031080919 scopus 로고    scopus 로고
    • Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A
    • Slusarski DC, Yang-Snyder J, Busa WB, Moon RT (1997) Modulation of embryonic intracellular Ca2+ signaling by Wnt-5A. Dev Biol 182: 114-120.
    • (1997) Dev Biol , vol.182 , pp. 114-120
    • Slusarski, D.C.1    Yang-Snyder, J.2    Busa, W.B.3    Moon, R.T.4
  • 7
    • 0034176626 scopus 로고    scopus 로고
    • Xenopus frizzled 7 can act in canonical and non-canonical Wnt signaling pathways: Implications on early patterning and morphogenesis
    • Medina A, Reintsch W, Steinbeisser H (2000) Xenopus frizzled 7 can act in canonical and non-canonical Wnt signaling pathways: implications on early patterning and morphogenesis. Mech Dev 92: 227-237.
    • (2000) Mech Dev , vol.92 , pp. 227-237
    • Medina, A.1    Reintsch, W.2    Steinbeisser, H.3
  • 9
    • 40549088942 scopus 로고    scopus 로고
    • The FE65 proteins and Alzheimer's disease
    • McLoughlin DM, Miller CC (2008) The FE65 proteins and Alzheimer's disease. J Neurosci Res 86: 744-754.
    • (2008) J Neurosci Res , vol.86 , pp. 744-754
    • McLoughlin, D.M.1    Miller, C.C.2
  • 10
    • 0035816661 scopus 로고    scopus 로고
    • A transcrsiptionally active complex of APP with Fe65 and histone acetyltransferase Tip60
    • Cao X, Sudhof TC (2001) A transcrsiptionally active complex of APP with Fe65 and histone acetyltransferase Tip60. Science 293: 115-120.
    • (2001) Science , vol.293 , pp. 115-120
    • Cao, X.1    Sudhof, T.C.2
  • 11
    • 33645218231 scopus 로고    scopus 로고
    • A dominant role for FE65 (APBB1) in nuclear signaling
    • Yang Z, Cool BH, Martin GM, Hu Q (2006) A dominant role for FE65 (APBB1) in nuclear signaling. J Biol Chem 281: 4207-4214.
    • (2006) J Biol Chem , vol.281 , pp. 4207-4214
    • Yang, Z.1    Cool, B.H.2    Martin, G.M.3    Hu, Q.4
  • 12
    • 9144262348 scopus 로고    scopus 로고
    • Isoform-specific knockout of FE65 leads to impaired learning and memory
    • Wang B, Hu Q, Hearn MG, Shimizu K, Ware CB, et al. (2004) Isoform-specific knockout of FE65 leads to impaired learning and memory. J Neurosci Res 75: 12-24.
    • (2004) J Neurosci Res , vol.75 , pp. 12-24
    • Wang, B.1    Hu, Q.2    Hearn, M.G.3    Shimizu, K.4    Ware, C.B.5
  • 13
    • 0036808580 scopus 로고    scopus 로고
    • Validated genomic approach to study differentially expressed genes in complex tissues
    • Wurmbach E, González-Maeso J, Yuen T, Ebersole BJ, Mastaitis JW, et al. (2002) Validated genomic approach to study differentially expressed genes in complex tissues. Neurochem Res 27: 1027-1033.
    • (2002) Neurochem Res , vol.27 , pp. 1027-1033
    • Wurmbach, E.1    González-Maeso, J.2    Yuen, T.3    Ebersole, B.J.4    Mastaitis, J.W.5
  • 14
    • 0035380762 scopus 로고    scopus 로고
    • Microarrays in brain research: The good, the bad and the ugly
    • Mirnics K (2001) Microarrays in brain research: the good, the bad and the ugly. Nat Rev Neurosci 2: 444-447.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 444-447
    • Mirnics, K.1
  • 15
    • 4444264384 scopus 로고    scopus 로고
    • Flanking gene and genetic background problems in genetically manipulated mice
    • Crusio WE (2004) Flanking gene and genetic background problems in genetically manipulated mice. Biol Psychiatry 56: 381-385.
    • (2004) Biol Psychiatry , vol.56 , pp. 381-385
    • Crusio, W.E.1
  • 16
    • 50149083752 scopus 로고    scopus 로고
    • Mammalian Rho GTPases: New insights into their functions from in vivo studies
    • Heasman SJ, Ridley AJ (2008) Mammalian Rho GTPases: new insights into their functions from in vivo studies. Nat Rev Mol Cell Biol 9: 690-701.
    • (2008) Nat Rev Mol Cell Biol , vol.9 , pp. 690-701
    • Heasman, S.J.1    Ridley, A.J.2
  • 17
    • 48249110960 scopus 로고    scopus 로고
    • Wnt signaling in neural circuit assembly
    • Salinas PC, Zou Y (2008) Wnt signaling in neural circuit assembly. Annu Rev Neurosci 31: 339-358.
    • (2008) Annu Rev Neurosci , vol.31 , pp. 339-358
    • Salinas, P.C.1    Zou, Y.2
  • 18
    • 0024492340 scopus 로고
    • Phenotypic diversification in human neuroblastoma cells: Expression of distinct neural crest lineages
    • Ciccarone V, Spengler BA, Meyers MB, Biedler JL, Ross RA (1989) Phenotypic diversification in human neuroblastoma cells: expression of distinct neural crest lineages. Cancer Res 49: 219-225.
    • (1989) Cancer Res , vol.49 , pp. 219-225
    • Ciccarone, V.1    Spengler, B.A.2    Meyers, M.B.3    Biedler, J.L.4    Ross, R.A.5
  • 19
    • 0034717794 scopus 로고    scopus 로고
    • Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells
    • Tohda C, Kuboyama T, Komatsu K (2000) Dendrite extension by methanol extract of Ashwagandha (roots of Withania somnifera) in SK-N-SH cells. Neuroreport 11: 1981-1985.
    • (2000) Neuroreport , vol.11 , pp. 1981-1985
    • Tohda, C.1    Kuboyama, T.2    Komatsu, K.3
  • 20
    • 33846068084 scopus 로고    scopus 로고
    • Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms
    • Ting JT, Kelley BG, Lambert TJ, Cook DG, Sullivan JM (2007) Amyloid precursor protein overexpression depresses excitatory transmission through both presynaptic and postsynaptic mechanisms. Proc Natl Acad Sci USA 104: 353-358.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 353-358
    • Ting, J.T.1    Kelley, B.G.2    Lambert, T.J.3    Cook, D.G.4    Sullivan, J.M.5
  • 21
    • 0031921466 scopus 로고    scopus 로고
    • Mutant genes in familial Alzheimer's disease and transgenic models
    • Price DL, Sisodia SS (1998) Mutant genes in familial Alzheimer's disease and transgenic models. Annu Rev Neurosci 21: 479-505.
    • (1998) Annu Rev Neurosci , vol.21 , pp. 479-505
    • Price, D.L.1    Sisodia, S.S.2
  • 22
    • 0030740829 scopus 로고    scopus 로고
    • Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: Implications of genetic background for single gene mutations and quantitative trait loci analyses
    • Owen EH, Logue SF, Rasmussen DL, Wehner JM (1997) Assessment of learning by the Morris water task and fear conditioning in inbred mouse strains and F1 hybrids: implications of genetic background for single gene mutations and quantitative trait loci analyses. Neuroscience 80: 1087-1099.
    • (1997) Neuroscience , vol.80 , pp. 1087-1099
    • Owen, E.H.1    Logue, S.F.2    Rasmussen, D.L.3    Wehner, J.M.4
  • 23
    • 69749090759 scopus 로고    scopus 로고
    • The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation. Learning and Memory
    • Wang Y, Zhang M, Moon C, Hu Q, Wang B, et al. (2009) The APP-interacting protein FE65 is required for hippocampus-dependent learning and long-term potentiation. Learning and Memory. Learn Mem 16: 537-544.
    • (2009) Learn Mem , vol.16 , pp. 537-544
    • Wang, Y.1    Zhang, M.2    Moon, C.3    Hu, Q.4    Wang, B.5
  • 24
    • 0029940557 scopus 로고    scopus 로고
    • Gene-targeting studies of mammalian behavior: Is it the mutation or the background genotype?
    • Gerlai R (1996) Gene-targeting studies of mammalian behavior: is it the mutation or the background genotype? Trends Neurosci 19: 177-181.
    • (1996) Trends Neurosci , vol.19 , pp. 177-181
    • Gerlai, R.1
  • 25
    • 77956399778 scopus 로고
    • Techniques for the genetic analysis of brain and behavior: Focus on the mouse
    • Goldowiz D, Wahlsten D, Wilmer RE, eds
    • Festing MFW (1992) In: Goldowiz D, Wahlsten D, Wilmer RE, eds. Techniques for the genetic analysis of brain and behavior: Focus on the mouse. Elsevier. pp 17-38.
    • (1992) Elsevier , pp. 17-38
    • Festing, M.F.W.1
  • 26
    • 0034821770 scopus 로고    scopus 로고
    • Mapping of quantitative trait loci with knockout/congenic strains
    • Bolivar VJ, Cook MN, Flaherty L (2001) Mapping of quantitative trait loci with knockout/congenic strains. Genome Res 11: 1549-1552.
    • (2001) Genome Res , vol.11 , pp. 1549-1552
    • Bolivar, V.J.1    Cook, M.N.2    Flaherty, L.3
  • 27
    • 0029133369 scopus 로고
    • The expression of two splice variants of metabotropic glutamate receptor subtype 5 in the rat brain and neuronal cells during development
    • Minakami R, Iida K, Hirakawa N, Sugiyama H (1995) The expression of two splice variants of metabotropic glutamate receptor subtype 5 in the rat brain and neuronal cells during development. J Neurochem 65: 1536-1542.
    • (1995) J Neurochem , vol.65 , pp. 1536-1542
    • Minakami, R.1    Iida, K.2    Hirakawa, N.3    Sugiyama, H.4
  • 28
    • 5444222139 scopus 로고    scopus 로고
    • Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development
    • Liu XB, Murray KD, Jones EG (2004) Switching of NMDA receptor 2A and 2B subunits at thalamic and cortical synapses during early postnatal development. J Neurosci 24: 8885-8895.
    • (2004) J Neurosci , vol.24 , pp. 8885-8895
    • Liu, X.B.1    Murray, K.D.2    Jones, E.G.3
  • 29
    • 0035654078 scopus 로고    scopus 로고
    • Dendritic spines: Structure, dynamics and regulation
    • Hering H, Sheng M (2001) Dendritic spines: structure, dynamics and regulation. Nat Rev Neurosci 2: 880-888.
    • (2001) Nat Rev Neurosci , vol.2 , pp. 880-888
    • Hering, H.1    Sheng, M.2
  • 30
    • 20444368053 scopus 로고    scopus 로고
    • Neuronal proteins custom designed by alternative splicing
    • Lipscombe D (2005) Neuronal proteins custom designed by alternative splicing. Curr Opin Neurobiol 15: 358-363.
    • (2005) Curr Opin Neurobiol , vol.15 , pp. 358-363
    • Lipscombe, D.1
  • 31
    • 33749054403 scopus 로고    scopus 로고
    • Splicing regulation in neurologic disease
    • Licatalosi DD, Darnell RB (2006) Splicing regulation in neurologic disease. Neuron 52: 93-101.
    • (2006) Neuron , vol.52 , pp. 93-101
    • Licatalosi, D.D.1    Darnell, R.B.2
  • 32
    • 70350512023 scopus 로고    scopus 로고
    • Alternative splicing of G protein-coupled receptors: Physiology and pathophysiology
    • Epub ahead of print
    • Markovic D, Challiss RA (2009) Alternative splicing of G protein-coupled receptors: physiology and pathophysiology. Cell Mol Life Sci [Epub ahead of print].
    • (2009) Cell Mol Life Sci
    • Markovic, D.1    Challiss, R.A.2
  • 33
    • 0035504328 scopus 로고    scopus 로고
    • Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: Prototypic family C G-protein-coupled receptors
    • Hermans E, Challiss RA (2001) Structural, signalling and regulatory properties of the group I metabotropic glutamate receptors: prototypic family C G-protein-coupled receptors. Biochem J 359: 465-484.
    • (2001) Biochem J , vol.359 , pp. 465-484
    • Hermans, E.1    Challiss, R.A.2
  • 34
    • 2442668393 scopus 로고    scopus 로고
    • Desensitization and internalization of metabotropic glutamate receptor 1a following activation of heterologous Gq/11-coupled receptors
    • Mundell SJ, Pula G, McIlhinney RA, Roberts PJ, Kelly E (2004) Desensitization and internalization of metabotropic glutamate receptor 1a following activation of heterologous Gq/11-coupled receptors. Biochemistry 43: 7541-7551.
    • (2004) Biochemistry , vol.43 , pp. 7541-7551
    • Mundell, S.J.1    Pula, G.2    McIlhinney, R.A.3    Roberts, P.J.4    Kelly, E.5
  • 35
    • 0037088919 scopus 로고    scopus 로고
    • Alternative splicing unmasks dendritic and axonal targeting signals in metabotropic glutamate receptor 1
    • Francesconi A, Duvoisin RM (2002) Alternative splicing unmasks dendritic and axonal targeting signals in metabotropic glutamate receptor 1. J Neurosci 22: 2196-2205.
    • (2002) J Neurosci , vol.22 , pp. 2196-2205
    • Francesconi, A.1    Duvoisin, R.M.2
  • 36
    • 0037862083 scopus 로고    scopus 로고
    • The 'magic tail' of G proteincoupled receptors: An anchorage for functional protein networks
    • Bockaert J, Marin P, Dumuis A, Fagni L (2003) The 'magic tail' of G proteincoupled receptors: an anchorage for functional protein networks. FEBS Lett 546: 65-72.
    • (2003) FEBS Lett , vol.546 , pp. 65-72
    • Bockaert, J.1    Marin, P.2    Dumuis, A.3    Fagni, L.4
  • 37
    • 0034916230 scopus 로고    scopus 로고
    • PDZ domains and the organization of supramolecular complexes
    • Sheng M, Sala C (2001) PDZ domains and the organization of supramolecular complexes. Annu Rev Neurosci 24: 1-29.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 1-29
    • Sheng, M.1    Sala, C.2
  • 38
    • 0036783234 scopus 로고    scopus 로고
    • Organisation of G-protein-coupled receptor signaling complexes by scaffolding proteins
    • Kreienkamp HJ (2002) Organisation of G-protein-coupled receptor signaling complexes by scaffolding proteins. Curr Opin Pharmacol 2: 581-586.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 581-586
    • Kreienkamp, H.J.1
  • 39
    • 0037083370 scopus 로고    scopus 로고
    • A PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins
    • Kitano J, Kimura K, Yamazaki Y, Soda T, Shigemoto R, et al. (2002) a PDZ domain-containing protein, links a protein complex formation of group 1 metabotropic glutamate receptors and the guanine nucleotide exchange factor cytohesins. J Neurosci 22: 1280-1289.
    • (2002) J Neurosci , vol.22 , pp. 1280-1289
    • Kitano, J.1    Kimura, K.2    Yamazaki, Y.3    Soda, T.4    Shigemoto, R.5
  • 40
    • 0033617473 scopus 로고    scopus 로고
    • Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex
    • Hillier BJ, Christopherson KS, Prehoda KE, Bredt DS, Lim WA (1999) Unexpected modes of PDZ domain scaffolding revealed by structure of nNOS-syntrophin complex. Science 284: 812-815.
    • (1999) Science , vol.284 , pp. 812-815
    • Hillier, B.J.1    Christopherson, K.S.2    Prehoda, K.E.3    Bredt, D.S.4    Lim, W.A.5
  • 41
    • 0033485891 scopus 로고    scopus 로고
    • Alternatively spliced isoforms of FE65 serve as neuron-specific and non-neuronal markers
    • Hu Q, Hearn MG, Jin LW, Bressler SL, Martin GM (1999) Alternatively spliced isoforms of FE65 serve as neuron-specific and non-neuronal markers. J Neurosci Res 58: 632-640.
    • (1999) J Neurosci Res , vol.58 , pp. 632-640
    • Hu, Q.1    Hearn, M.G.2    Jin, L.W.3    Bressler, S.L.4    Martin, G.M.5
  • 42
    • 0034123008 scopus 로고    scopus 로고
    • Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions
    • Hu Q, Jin LW, Starbuck MY, Martin GM (2000) Broadly altered expression of the mRNA isoforms of FE65, a facilitator of beta amyloidogenesis, in Alzheimer cerebellum and other brain regions. J Neurosci Res 60: 73-86.
    • (2000) J Neurosci Res , vol.60 , pp. 73-86
    • Hu, Q.1    Jin, L.W.2    Starbuck, M.Y.3    Martin, G.M.4
  • 43
    • 27344438154 scopus 로고    scopus 로고
    • Hippocampal neurons express a calcineurin-activated adenylyl cyclase
    • Chan GC, Tonegawa S, Storm DR (2005) Hippocampal neurons express a calcineurin-activated adenylyl cyclase. J Neurosci 25: 9913-9918.
    • (2005) J Neurosci , vol.25 , pp. 9913-9918
    • Chan, G.C.1    Tonegawa, S.2    Storm, D.R.3
  • 44
    • 0037372098 scopus 로고    scopus 로고
    • Prediction of beta-turns in proteins from multiple alignment using neural network
    • Kaur H, Raghava GPS (2003) Prediction of beta-turns in proteins from multiple alignment using neural network. Protein Science 12: 627-634.
    • (2003) Protein Science , vol.12 , pp. 627-634
    • Kaur, H.1    Raghava, G.P.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.