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See the Supporting Information for a full description of the computational procedure used to locate the respective diastereomeric transition states for lithiation. It should be noted that due to the stereochemical complexity of this deprotonation process, it was necessary to compute thirty-two different transition state structures (i.e., 16 for pro-S and 16 for pro-R deprotonation). The energies and coordinate data of these thirtytwo transition states are also found in the Supporting Information.
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See the Supporting Information for 1H and 3C NMR spectra of all compounds.
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